Gene interactions and pathways from curated databases and text-mining

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CTNNB1 — IL8

Text-mined interactions from Literome

Lévy et al., J Biol Chem 2002 : Transcriptional activation of interleukin-8 by beta-catenin-Tcf4 ... The IL-8 promoter contains a unique consensus Tcf/Lef site that is critical for IL-8 activation by beta-catenin ... Ectopic expression of beta-catenin in hepatoma cells promoted IL-8 secretion, which stimulated endothelial cell migration ... These data define IL-8 as a Wnt target and suggest that IL-8 induction by beta-catenin might be implicated in developmental and tumorigenic processes
Sun et al., Am J Physiol Gastrointest Liver Physiol 2005 (Salmonella Infections) : Accordingly, constitutively active beta-catenin was found to inhibit the secretion of IL-8
Masckauchán et al., Angiogenesis 2005 : Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells