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AGTR1 — AKT2
Text-mined interactions from Literome
Kawahara et al., J Cardiovasc Pharmacol 2005
(Hypertension) :
Recent studies have shown that
angiotensin II type 1 (AT1) receptor mediated
Akt activation induces vascular smooth muscle cell ( VSMC ) dedifferentiation in vitro
Olivares-Reyes et al., Mol Pharmacol 2005
:
The dependence of these responses on caveolin was indicated by the finding that cholesterol depletion of C9 cells abolished Ang II-induced inositol phosphate production,
activation of
Akt/PKB and ERK1/2, and
AT(1)-R internalization
Yu et al., J Cell Biochem 2007
:
Activation of ERK, JNK,
Akt , and G-protein coupled signaling by hybrid angiotensin II
AT1/bradykinin B2 receptors expressed in HEK-293 cells
Wang et al., Biochem Pharmacol 2013
:
It was found that mRNA, protein, and current density of K ( Ca ) 3.1 channels were greatly enhanced in cultured cardiac fibroblasts treated with 1 µM Ang II, and the effects were countered by the
angiotensin type 1 receptor ( AT1R ) blocker losartan, the p38-MAPK inhibitor SB203580, the ERK1/2 inhibitor PD98059, and the
PI3K/Akt inhibitor LY294002