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IL10 — MKNK1
Text-mined interactions from Literome
Chan et al., J Biol Chem 2012
:
Furthermore, activating SHIP1 using a small-molecule agonist mimics the inhibitory
effect of
IL-10 on
Mnk1 phosphorylation and TNFa translation
Fukunaga et al., EMBO J 1997
:
Further,
MNK1 was activated upon
stimulation of HeLa cells with 12-O-tetradecanoylphorbol-13-acetate, fetal calf serum, anisomycin, UV irradiation, tumor necrosis factor-alpha,
interleukin-1beta , or osmotic shock, and the activation by these stimuli was differentially inhibited by the MEK inhibitor PD098059 or the p38 MAP kinase inhibitor SB202190