Gene interactions and pathways from curated databases and text-mining

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EGFR — MRXS5

Text-mined interactions from Literome

Merchant et al., Surgery 2005 (Colonic Neoplasms) : We have shown that activation of the EGFR induces up-regulation of cyclooxygenase 2, basolateral release of prostaglandins (PGs) , and mitogenesis in a polarizing human colon cancer cell line, HCA-7
Akhtar et al., Acta Ophthalmol 2009 (Diabetes Mellitus, Experimental) : This study examined the role of epidermal growth factor receptor (EGFR) signalling on the organization and remodelling of collagen fibrils ( CFs ) and proteoglycans (PGs) in the stroma of diabetic rat cornea
Coffey et al., Proc Natl Acad Sci U S A 1997 : These findings show that activation of the EGFR stimulates COX-2 production and its translocation to the nucleus, vectorial release of PGs , and mitogenesis in polarized HCA-7 Colony 29 cells