◀ Back to MYLIP
AGO2 — MYLIP
Text-mined interactions from Literome
Verrier et al., Glia 2009
:
Over-expression of
miR-29a enhances the association of PMP22 RNA with
Argonaute 2 , a protein involved in miRNA function, and reduces the steady-state levels of PMP22
Elcheva et al., Mol Cell 2009
:
Argonaute2 interacts with the same region of betaTrCP1 mRNA in an
miR-183 dependent manner ... Here we demonstrate that CRD-BP prevents degradation of betaTrCP1 mRNA by attenuating its
miR-183 dependent interaction with
Ago2
Tsai et al., Biochem J 2009
:
Furthermore, the activity of
mir346 does not
require Ago-2 ( Argonaute 2 )
Kim et al., Aging Cell 2011
:
Silencing of
Ago2 in ATSCs significantly
induces upregulation of miR10b and
miR23b expression
Zhang et al., PloS one 2012
:
Transfection assay revealed that both Ago1 and
Ago2 synergistically
induced miR-21 and miR-21* when the mir-21 plasmid was co-transfected with either
Shimakami et al., J Virol 2012
(Genomic Instability) :
These 3 ' supplementary base pair interactions of
miR-122 are functionally important and are
required for
Ago2 recruitment to HCV RNA by miR-122, miR-122 mediated stabilization of HCV RNA, and production of infectious virus
Zhang et al., J Biol Chem 2013
(Carcinoma, Hepatocellular...) :
The up-regulation by
miR-490-3p also
required the participation of
Ago2
Tattikota et al., Mol Cell Proteomics 2013
:
In addition, the loss of
Ago2 resulted in the increased expression of
miR-375 target genes, including gephyrin and ywhaz
Conrad et al., PloS one 2013
(Carcinoma, Hepatocellular...) :
Here, we show that
Argonaute (Ago) 2 protein binds to the HCV 5'-UTR in a
miR-122 dependent manner, whereas the HCV 3'-UTR does not bind Ago2
Bradrick et al., RNA 2013
:
Similar to functional assays, we found that association of immobilized HCV internal ribosome entry site ( IRES ) RNA with endogenous
Ago2 requires both
miR-122 expression and intact miR-122 target sites in cis