Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
TLR3 ▸ ICAM1 ▸ NM ▸ TLR5 ▸ CD40 ▸ PTGS2 ▸ IL13 ▸
VEGFA ▸ AHSA1 ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ TLR7 ▸
TLR8 ▸ IL3 ▸ TLR6 ▸ RNF19A ▸ IL15 ▸ TLR10 ▸ IL33 ▸
TGFB1 ▸ IL5 ▸ LTA ▸ TCF4 ▸ F2RL1 ▸ IL18 ▸ TCF21 ▸
NOS2 ▸ TCF20 ▸ TCF23 ▸ TCF25 ▸ TCF12 ▸ CRK ▸ IL22 ▸
TCF19 ▸ TCF7 ▸ TCF3 ▸ TCF15 ▸ TCF24 ▸ PIK3CA ▸ NFKBIA ▸
PIK3R1 ▸ CSE ▸ NA ▸ IL1RN ▸ MMP9 ▸ IL32 ▸ LPA ▸
WDR61 ▸ HGF ▸ EGF ▸ CTR9 ▸ CDC73 ▸ IL31 ▸ GRAP2 ▸
APOB ▸ LEO1 ▸ PAF1 ▸ IFNB1 ▸ S100A8 ▸ CXCR1 ▸ IL7 ▸
IL11 ▸ MMP2 ▸ IL16 ▸ IL9 ▸ IL25 ▸ IL20 ▸ IL19 ▸
IL21 ▸ FGF2 ▸ ITGAM ▸ POLDIP2 ▸ IL26 ▸ IL34 ▸ IL37 ▸
IL24 ▸ FAS ▸ MMP3 ▸ INS ▸ IL27 ▸ SAA1 ▸ NOS1 ▸
MIF ▸ EGFR ▸ AKT3 ▸ PI3 ▸ ALB ▸ CXCR2 ▸ AKT1 ▸
AKT2 ▸ CRP ▸ IKBKB ▸ MMP13 ▸ CASP3 ▸ NOX1 ▸ CASP4 ▸
CD14 ▸ MMP1 ▸ CALM3 ▸ CD40LG ▸ NOX4 ▸ F2R ▸ CASP9 ▸
CASP8 ▸ CASP6 ▸ CASP5 ▸ CASP1 ▸ CASP10 ▸ CASP12 ▸ CASP16 ▸
NOS3 ▸ CASP7 ▸ CASP2 ▸ CASP14 ▸ PTX3 ▸ NOX5 ▸ NOX3 ▸
PLG ▸ HMGB1 ▸ TGFB2 ▸ CHUK ▸ PTK7 ▸ TNFSF10 ▸ ITGB2 ▸
NOD1 ▸ SELE ▸ PTK6 ▸ MYLIP ▸ IGF1 ▸ PTK2 ▸ MYD88 ▸
LIF ▸ TREM1 ▸ PRG2 ▸ MMP8 ▸ IFNA2 ▸ MAP3K7 ▸ MUC1 ▸
PRG3 ▸ IKBKG ▸ GP6 ▸ LEP ▸ GP2 ▸ SRC ▸ IL12B ▸
ERVK-6 ▸ GP9 ▸ PRG4 ▸ PTX4 ▸ GP5 ▸ STAT3 ▸ CXCL12 ▸
IFNA16 ▸ SOD2 ▸ PLD2 ▸ CSF3 ▸ HNRNPH1 ▸ IFNA21 ▸ WNK1 ▸
PRKAR2A ▸ LTB ▸ IFNA17 ▸ IFNA13 ▸ IFNA10 ▸ HDAC2 ▸ HNRNPF ▸
MMP14 ▸ SOD3 ▸ IFNA6 ▸ S100A12 ▸ IFNA14 ▸ VCAM1 ▸ IFNA8 ▸
CRH ▸ MPO ▸ PTBP1 ▸ IFNA1 ▸ IFNA5 ▸ PRKACG ▸ PTBP2 ▸
SOD1 ▸ MMP7 ▸ PAM ▸ PRKAR2B ▸ IL12A ▸ PRKAR1B ▸ VIP ▸
IFNA4 ▸ PRKAR1A ▸ SERPINE1 ▸ IFNA7 ▸ PRKACB ▸ CCL3 ▸ MMP25 ▸
MMP24 ▸ MMP16 ▸ CAT ▸ MMP26 ▸ MMP10 ▸ TGFB3 ▸ FGF1 ▸
ELANE ▸ MMP21 ▸ MMP17 ▸ SPP1 ▸ PLD1 ▸ EGR1 ▸ EDN1 ▸
CSK ▸ TNFRSF1A ▸ IL1R1 ▸ MMP28 ▸ CXCL10 ▸ MMP27 ▸ SETD2 ▸
MSH3 ▸ HDAC1 ▸ MMP15 ▸ MMP19 ▸ NOD2 ▸ MMP12 ▸ MMP20 ▸
MMP11 ▸ QRICH1 ▸ PLA2G1B ▸ CD4 ▸ ANGPT2 ▸ FGF7 ▸ QRICH2 ▸
SST ▸ PLD6 ▸ CD8A ▸ MSH6 ▸ PLD5 ▸ PLD4 ▸ MAP2K1 ▸
MSH2 ▸ AHR ▸ FASLG ▸ TAB1 ▸ MSH5 ▸ SYT1 ▸ PLD3 ▸
TRAF6 ▸ MSH4 ▸ NAALADL1 ▸ HDAC6 ▸ CXCL1 ▸ SAA2 ▸ P2RY6 ▸
FGF23 ▸ FGF19 ▸ C1QA ▸ STAT1 ▸ FGF3 ▸ ADIPOQ ▸ SELP ▸
FGF5 ▸ TNFSF12 ▸ FGF12 ▸ ETS1 ▸ SELL ▸ CD38 ▸ TXN ▸
CSF1 ▸ FGF16 ▸ FGF22 ▸ FGF10 ▸ HDAC5 ▸ ITGB1 ▸ FGF9 ▸
LTF ▸ FGF11 ▸ FGF20 ▸ PPARG ▸ HDAC3 ▸ CD28 ▸ HMOX1 ▸
FGF13 ▸ FGF17 ▸ HSPD1 ▸ STX2 ▸ PDLIM7 ▸ SOCS3 ▸ RAC1 ▸
CD46 ▸ CSRP1 ▸ FGF21 ▸ NGF ▸ C1QB ▸ FGF6 ▸ FGF8 ▸
FGF14 ▸ FGF4 ▸ FGF18 ▸ CD8B ▸ TNMD ▸ MUC13 ▸ TNFSF13B ▸
TRPV1 ▸ SETBP1 ▸ CISH ▸ HDAC4 ▸ RHO ▸ CR1 ▸ MUC12 ▸
PRTN3 ▸ HDAC7 ▸ ANGPT1 ▸ GPI ▸ SAA4 ▸ STX1A ▸ RHOA ▸
APC ▸ PF4 ▸ MTX1 ▸ CXCR4 ▸ MUC16 ▸ ST8SIA2 ▸ STAT4 ▸
ANG ▸ PPARA ▸ PLAU ▸ MUC15 ▸ HDAC8 ▸ MUC17 ▸ HSPG2 ▸
CPOX ▸ RBBP7 ▸ MUC20 ▸ RBBP4 ▸ HDAC11 ▸ PLA2G4A ▸ HSPB1 ▸
HDAC10 ▸ MUC6 ▸ NAP1L4 ▸ MUC4 ▸ ITIH4 ▸ HDAC9 ▸ CXCR3 ▸
CD79A ▸ TAT ▸ CFTR ▸ BCL3 ▸ PRKCD ▸ MUC19 ▸ HES1 ▸
AGTR2 ▸ PDGFB ▸ IL2RA ▸ PDCD11 ▸ MUC7 ▸ ECM2 ▸ ECM1 ▸
MTOR ▸ NPS ▸ MUC22 ▸ MUC2 ▸ MUC21 ▸ MUC8 ▸ PRR21 ▸
PRR16 ▸ PRR26 ▸ OSM ▸ PRR5 ▸ SIGLEC7 ▸ MET ▸ SELPLG ▸
BCL10 ▸ ADAM11 ▸ SMAD3 ▸ HES7 ▸ TF ▸ PRR14 ▸ ADCYAP1 ▸
BCL2 ▸ RENBP ▸ FCGR1A ▸ TAC3 ▸ ETS2 ▸ NR4A2 ▸ PRKAA2 ▸
CXCL9 ▸ HES3 ▸ MAP2K7 ▸ IBD4 ▸ RNASE3 ▸ ESR1 ▸ NR0B1 ▸
MUC5AC ▸ HES2 ▸ TPO ▸ MT3 ▸ PRR25 ▸ CCL20 ▸ ELF3 ▸
FGG ▸ PRDX2 ▸ BRAF ▸ ICAM5 ▸ IL17F ▸ UTP6 ▸ IFI44 ▸
IBD8 ▸ ICOSLG ▸ PRKAB1 ▸ A2M ▸ CXCL6 ▸ IRAK1 ▸ PAEP ▸
LPL ▸ HDC ▸ PRR22 ▸ PRR12 ▸ MPL ▸ TAC1 ▸ FOXO3 ▸
CHI3L1 ▸ CALM1 ▸ DUSP1 ▸ IBD6 ▸ ADAM17 ▸ ICAM2 ▸ MT4 ▸
APEX1 ▸ IBD5 ▸ PGF ▸ GRP ▸ SEA ▸ PRKAB2 ▸ PRR24 ▸
CTNNB1 ▸ PRKCA ▸ ELF4 ▸ IL1R2 ▸ IBD2 ▸ ICAM4 ▸ IRAK3 ▸
PRR3 ▸ PRR11 ▸ CYP1A1 ▸ FGA ▸ DEFA1 ▸ PTAFR ▸ IBD9 ▸
TFPI ▸ CALM2 ▸ EMD ▸ PRR13 ▸ PRKAG2 ▸ ARG2 ▸ PRR4 ▸
PRR15 ▸ TAC4 ▸ EPO ▸ PRL ▸ MAP3K1 ▸ IBD7 ▸ HES6 ▸
PKD1 ▸ ARG1 ▸ PRR7 ▸ DDIT3 ▸ HES5 ▸ CXCL11 ▸ UTP20 ▸
AZU1 ▸ CXCL17 ▸ PRKAA1 ▸ TGFA ▸ ICAM3 ▸ UTP18 ▸ UTP3 ▸
ROCK2 ▸ HES4 ▸ IBD3 ▸ CCR5 ▸ PRR19 ▸ NTS ▸ UTP15 ▸
NUP43 ▸ TP53 ▸ PRR18 ▸ JAK2 ▸ PRR9 ▸ RELB ▸ PRKAG1 ▸
UTP23 ▸ HBEGF ▸ PGD ▸ WNT16 ▸ PARK2 ▸ KLRB1 ▸ MRXS5 ▸
MAP2K5 ▸ SCARB1 ▸ IFIH1 ▸ CYP1A2 ▸ HIF1A ▸ CAPN15 ▸ TNFRSF1B ▸
ADAM10 ▸ NR4A1 ▸ PAK3 ▸ AGTR1 ▸ FUT7 ▸ FGB ▸ WNT6 ▸
SERPINE2 ▸ HCG14 ▸ PAK6 ▸ BCR ▸ HLA-DRB1 ▸ HMGB4 ▸ CAPN11 ▸
C3 ▸ ALX1 ▸ ALX3 ▸ IRS1 ▸ SERPINB2 ▸ TPT1 ▸ HCG17 ▸
CAPN14 ▸ ACKR3 ▸ FUT9 ▸ SYK ▸ CNR2 ▸ ELF1 ▸ DEFA1B ▸
ELF5 ▸ CEACAM1 ▸ ELF2 ▸ FOXO6 ▸ AREG ▸ BCL6 ▸ CCL5 ▸
CDH5 ▸ PAK4 ▸ CXCL14 ▸ CAPN7 ▸ ROCK1 ▸ CAPN2 ▸ UCN2 ▸
GRPR ▸ MAPKAPK2 ▸ NPY4R ▸ DUOX1 ▸ CAPN1 ▸ POU2F1 ▸ GAST ▸
CSH1 ▸ MYO16 ▸ PTPN11 ▸ FXYD1 ▸ HRAS ▸ SOAT1 ▸ VASP ▸
CP ▸ MAP2K4 ▸ SMAD5 ▸ ATP8A2 ▸ DPM1 ▸ CX3CL1 ▸ FCGR2B ▸
GHRH ▸ KDR ▸ HMGB2 ▸ ANPEP ▸ HRH1 ▸ KRT10 ▸ HCG23 ▸
CSH2 ▸ PTGS1 ▸ BLM ▸ HCG11 ▸ MEPE ▸ FOXP3 ▸ APOE ▸
SMAD1 ▸ C1orf228 ▸ PINK1 ▸ KSR2 ▸ RNASE2 ▸ FMR1 ▸ PTPN22 ▸
FUT10 ▸ RAC3 ▸ CYP19A1 ▸ MAP2K2 ▸ HMGB3 ▸ HCG27 ▸ VAV1 ▸
CEACAM6 ▸ VDR ▸ GH1 ▸ CD86 ▸ CAPN8 ▸ KLK3 ▸ TBP ▸
CD163 ▸ MEFV ▸ F10 ▸ TRNAI1 ▸ CNR1 ▸ GRB10 ▸ CTSB ▸
HCG24 ▸ SMAD4 ▸ GRB7 ▸ CAPN6 ▸ CDC42 ▸ CCL4 ▸ CPB1 ▸
TACR1 ▸ MKNK1 ▸ HCG9 ▸ SFXN1 ▸ SPP2 ▸ NLRP3 ▸ APOA1 ▸
IL23A ▸ TNFRSF9 ▸ CPB2 ▸ CAPN10 ▸ LBP ▸ HCG26 ▸ CAPN5 ▸
PROK1 ▸ MYO19 ▸ WNT2 ▸ HCG18 ▸ MAP2K6 ▸ PTHLH ▸ CTGF ▸
SPESP1 ▸ CXCL5 ▸ GAL ▸ HCG16 ▸ CAPN13 ▸ ABL1 ▸ CXCL13 ▸
CTSS ▸ DDX58 ▸ FUT6 ▸ HCG21 ▸ CDH1 ▸ THBD ▸ TNPO1 ▸
STAT5A ▸ TNP1 ▸ CXCL3 ▸ PAK1 ▸ FUT5 ▸ ALOX5 ▸ FGFR2 ▸
IGF2 ▸ CD1D ▸ WNT4 ▸ FCER2 ▸ PARK7 ▸ RETN ▸ FOSL1 ▸
CD69 ▸ MTA1 ▸ PAH ▸ CSTA ▸ REL ▸ TSC22D3 ▸ CXCR6 ▸
FUT2 ▸ CEBPB ▸ ADAM19 ▸ PDGFA ▸ WNT1 ▸ CAPN12 ▸ PAK2 ▸
PGP ▸ CGN ▸ BPI ▸ FUT4 ▸ MBP ▸ NAMPT ▸ OXA1L ▸
SMAD2 ▸ CXCL2 ▸ RAC2 ▸ HCG4 ▸ APOA2 ▸ NPY6R ▸ FUT1 ▸
GRB14 ▸ ARSA ▸ CEBPA ▸ DNASE1 ▸ DPM2 ▸ ELAVL1 ▸ CAPN3 ▸
HCG20 ▸ S100A9 ▸ NPY ▸ ASIP ▸ DNASE2 ▸ ADM ▸ IDO1 ▸
JAK3 ▸ WNT11 ▸ DPM3 ▸ HCG15 ▸ TMSB4X ▸ PDCD4 ▸ PITX1 ▸
SMAD7 ▸ MTA2 ▸ RABEPK ▸ CD2 ▸ MAP2K3 ▸ F2RL2 ▸ HCG25 ▸
FUT11 ▸ CA1 ▸ GRB2 ▸ SMAD6 ▸ FUT3 ▸ ITGA5 ▸ HCG22 ▸
GSTM1 ▸ RAG1 ▸ MPG ▸ HBD ▸ VCP ▸ MTA3 ▸ ALX4 ▸
PAK7 ▸ FOXO4 ▸ CD83 ▸ AR ▸ SMAD9 ▸ GIP ▸ CD44 ▸
JAK1 ▸ HCG8 ▸ TNFSF11 ▸ NFKBIZ ▸ MYO10 ▸ SLPI ▸ CAPN9 ▸
F7 ▸ TRAF2 ▸ MYO6 ▸ FOXO1 ▸ TEC ▸ WNT3 ▸ TNP2 ▸
BMP2 ▸ FUT8 ▸ CXCL16 ▸ ADRA2A ▸ LPAR5 ▸ GPER1 ▸ C5AR1 ▸
TAS2R30 ▸ U2AF1 ▸ MTNR1B ▸ TAS2R13 ▸ XCR1 ▸ CHRM2 ▸ INSL5 ▸
NPY2R ▸ GNG2 ▸ S1PR2 ▸ PPBP ▸ ADORA3 ▸ GNAI1 ▸ HCAR3 ▸
PTGER3 ▸ HTR1E ▸ APLNR ▸ CCR2 ▸ GALR3 ▸ ADRA2B ▸ CCL16 ▸
ADORA1 ▸ DRD2 ▸ RXFP3 ▸ GNB1 ▸ HCAR1 ▸ HTR5A ▸ S1PR3 ▸
CCR8 ▸ MTNR1A ▸ TAS2R19 ▸ CCL28 ▸ P2RY13 ▸ P2RY12 ▸ S1PR5 ▸
TAS2R9 ▸ HTR1A ▸ PENK ▸ PTGDR2 ▸ CCL27 ▸ TAS2R40 ▸ PNOC ▸
TAS2R41 ▸ CCL25 ▸ TAS2R4 ▸ GABBR2 ▸ GALR2 ▸ DRD4 ▸ GALR1 ▸
TAS2R1 ▸ CHRM4 ▸ SUCNR1 ▸ GRM3 ▸ GNAT3 ▸ GNAI2 ▸ TAS2R42 ▸
TAS2R31 ▸ HTR1D ▸ PYY ▸ NPY1R ▸ SSTR4 ▸ TAS2R39 ▸ TAS2R16 ▸
GRM2 ▸ MCHR1 ▸ RXFP4 ▸ DARC ▸ C3AR1 ▸ SSTR2 ▸ OXGR1 ▸
OPRL1 ▸ GRM4 ▸ TAS2R10 ▸ DRD3 ▸ MT-RNR2 ▸ TAS2R20 ▸ CCR6 ▸
HEBP1 ▸ SSTR3 ▸ NMUR1 ▸ ANXA1 ▸ CCL19 ▸ CX3CR1 ▸ NPY5R ▸
P2RY4 ▸ GRM8 ▸ GABBR1 ▸ TAS2R5 ▸ CCR7 ▸ KNG1 ▸ PPY ▸
OPRK1 ▸ HCAR2 ▸ MCHR2 ▸ HRH3 ▸ TAS2R3 ▸ TAS2R45 ▸ NPBWR2 ▸
GRM6 ▸ CCR10 ▸ OPRD1 ▸ TAS2R8 ▸ FPR3 ▸ NMU ▸ HRH4 ▸
NPB ▸ FPR1 ▸ HTR1F ▸ TAS2R43 ▸ TAS2R38 ▸ S1PR1 ▸ GNAI3 ▸
TAS2R7 ▸ PDYN ▸ NMUR2 ▸ PMCH ▸ TAS2R50 ▸ OXER1 ▸ TAS2R14 ▸
NPBWR1 ▸ SSTR1 ▸ CCR4 ▸ CCR1 ▸ GRM7 ▸ CCR9 ▸ BDKRB2 ▸
TAS2R60 ▸ SSTR5 ▸ BDKRB1 ▸ ADRA2C ▸ HTR1B ▸ TAS2R46 ▸ S1PR4 ▸
Data information
Please see the Gene Interactions Track Manual.