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MAPK → IL-20: " We found that IL-20 significantly increased the expression of matrix metalloproteinase (MMP)-9 via binding activity of NF-?B and AP-1 in bladder cancer cells and stimulated the activation of ERK1/2, JNK, p38 MAPK , and JAK-STAT signaling "
ERK1/2 → IL-20: " We found that IL-20 significantly increased the expression of matrix metalloproteinase (MMP)-9 via binding activity of NF-?B and AP-1 in bladder cancer cells and stimulated the activation of ERK1/2 , JNK, p38 MAPK, and JAK-STAT signaling "
JAK-STAT → IL-20: " We found that IL-20 significantly increased the expression of matrix metalloproteinase (MMP)-9 via binding activity of NF-?B and AP-1 in bladder cancer cells and stimulated the activation of ERK1/2, JNK, p38 MAPK, and JAK-STAT signaling "
matrix metalloproteinase (MMP)-9 → IL-20: " We found that IL-20 significantly increased the expression of matrix metalloproteinase (MMP)-9 via binding activity of NF-?B and AP-1 in bladder cancer cells and stimulated the activation of ERK1/2, JNK, p38 MAPK, and JAK-STAT signaling "
ERK1/2 → IL-20: " Moreover, siRNA knockdown of IL-20R1 suppressed migration, invasion, ERK1/2 activation, and NF-?B mediated MMP-9 expression induced by IL-20 "
ERK1/2 → IL-20: " Moreover, siRNA knockdown of IL-20R1 suppressed migration, invasion, ERK1/2 activation, and NF-?B mediated MMP-9 expression induced by IL-20 "
MMP-9 → IL-20: " Moreover, siRNA knockdown of IL-20R1 suppressed migration, invasion, ERK1/2 activation, and NF-?B mediated MMP-9 expression induced by IL-20 "
p21 → IL-20: " Unexpectedly, the cell cycle inhibitor p21 ( WAF1 ) was induced by IL-20 treatment without altering cell cycle progression "
MMP-9 → ERK: " Blockade of p21 ( WAF1 ) function by siRNA reversed migration, invasion, activation of ERK signaling, MMP-9 expression, and activation of NF-?B in IL-20 treated cells "
p65 → IL-20: " In addition, IL-20 induced the activation of I?B kinase, the degradation and phosphorylation of I?Ba, and NF-?B p65 nuclear translocation, which was regulated by ERK1/2 "
NF-?B p65 → IL-20: " In addition, IL-20 induced the activation of I?B kinase, the degradation and phosphorylation of I?Ba, and NF-?B p65 nuclear translocation, which was regulated by ERK1/2 "
MMP-9 → p21: " This is the first report that p21 ( WAF1 ) is involved in ERK1/2 mediated MMP-9 expression via increased binding activity of NF-?B, which resulted in the induction of migration in IL-20/IL-20R1 dyad induced bladder cancer cells "
MMP-9 → ERK1/2: " This is the first report that p21 ( WAF1 ) is involved in ERK1/2 mediated MMP-9 expression via increased binding activity of NF-?B, which resulted in the induction of migration in IL-20/IL-20R1 dyad induced bladder cancer cells "