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I kappa B-alpha → LPS: " LPS induction of I kappa B-alpha degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, Tyrphostin b42 "
I kappa B-alpha → janus kinase 2: " LPS induction of I kappa B-alpha degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, Tyrphostin b42 "
iNOS → LPS: " LPS induction of I kappa B-alpha degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, Tyrphostin b42 "
iNOS → janus kinase 2: " LPS induction of I kappa B-alpha degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, Tyrphostin b42 "
iNOS → JAK2: " In FSDC the expression of iNOS protein and nitric oxide production, in response to the lipopolysaccharide (LPS) stimulus ( 5 microg/ml ), is inhibited by the specific inhibitor of the JAK2 , tyrphostin B42 with an half maximal inhibitory concentration ( IC ( 50 ) ) of 9.65 microM "
I kappa B-alpha ⊣ LPS: " In addition, LPS induces the activation of NF-kappa B, and tyrphostin B42 prevents the degradation of the cytosolic factor I kappa B-alpha and blocks the translocation of the NF-kappa B p65 protein subunit into the nucleus "
LPS → NF-kappa B: " In addition, LPS induces the activation of NF-kappa B , and tyrphostin B42 prevents the degradation of the cytosolic factor I kappa B-alpha and blocks the translocation of the NF-kappa B p65 protein subunit into the nucleus "
iNOS → NF-kappa B: " These results indicate that the JAK family of protein kinases and the transcription factor NF-kappa B are involved in the induction of iNOS protein expression in FSDC stimulated with LPS "