Mouse Gene Prim1 (ENSMUST00000026461.8) from GENCODE VM30
  Description: Mus musculus DNA primase, p49 subunit (Prim1), mRNA. (from RefSeq NM_008921)
Gencode Transcript: ENSMUST00000026461.8
Gencode Gene: ENSMUSG00000025395.15
Transcript (Including UTRs)
   Position: mm39 chr10:127,851,041-127,865,906 Size: 14,866 Total Exon Count: 13 Strand: +
Coding Region
   Position: mm39 chr10:127,851,118-127,865,654 Size: 14,537 Coding Exon Count: 13 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2022-06-02 18:33:23

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:127,851,041-127,865,906)mRNA (may differ from genome)Protein (417 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsMGIPubMedStanford SOURCE
UniProtKB

-  Comments and Description Text from UniProtKB
  ID: Q5FW94_MOUSE
DESCRIPTION: RecName: Full=DNA primase; EC=2.7.7.-;
SIMILARITY: Belongs to the eukaryotic-type primase small subunit family.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • D013749 Tetrachlorodibenzodioxin
  • D010634 Phenobarbital
  • C006780 bisphenol A
  • C006253 pirinixic acid
  • C049325 1,2-dithiol-3-thione
  • C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene
  • C111118 2',3,3',4',5-pentachloro-4-hydroxybiphenyl
  • C029497 2,3-bis(3'-hydroxybenzyl)butyrolactone
  • C023514 2,6-dinitrotoluene
  • D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
          more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -16.4077-0.213 Picture PostScript Text
3' UTR -39.70252-0.158 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002755 - DNA_primase_S
IPR014052 - DNA_primase_ssu_euk/arc

Pfam Domains:
PF01896 - DNA primase small subunit

ModBase Predicted Comparative 3D Structure on Q5FW94
FrontTopSide
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserNo orthologGenome BrowserGenome Browser
Gene Details    Gene Details
Gene Sorter    Gene Sorter
 RGDEnsembl WormBaseSGD
Protein SequenceProtein SequenceProtein Sequence Protein SequenceProtein Sequence
AlignmentAlignmentAlignment AlignmentAlignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003896 DNA primase activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016740 transferase activity

Biological Process:
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of RNA primer


-  Descriptions from all associated GenBank mRNAs
  J04620 - Mouse primase p49 subunit (priA) mRNA, complete cds.
BC089544 - Mus musculus DNA primase, p49 subunit, mRNA (cDNA clone MGC:107288 IMAGE:30504228), complete cds.
AK089063 - Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:E430038C03 product:DNA primase, p49 subunit, full insert sequence.
AK160831 - Mus musculus 10 days embryo whole body cDNA, RIKEN full-length enriched library, clone:3426401K05 product:DNA primase, p49 subunit, full insert sequence.
AK088557 - Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:E430020E06 product:DNA primase, p49 subunit, full insert sequence.
D13544 - Mus musculus mRNA for primase small subunit, complete cds.
AK169632 - Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:E430002P10 product:DNA primase, p49 subunit, full insert sequence.
AK133878 - Mus musculus 8 days embryo whole body cDNA, RIKEN full-length enriched library, clone:5730478J06 product:DNA primase, p49 subunit, full insert sequence.
AK011456 - Mus musculus 10 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2610019C06 product:DNA primase, p49 subunit, full insert sequence.
AK178164 - Mus musculus cDNA, clone:Y0G0105K17, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000047864, based on BLAT search.

-  Other Names for This Gene
  Alternate Gene Symbols: ENSMUST00000026461.1, ENSMUST00000026461.2, ENSMUST00000026461.3, ENSMUST00000026461.4, ENSMUST00000026461.5, ENSMUST00000026461.6, ENSMUST00000026461.7, NM_008921, Q5FW94, Q5FW94_MOUSE, uc011xpx.1, uc011xpx.2, uc011xpx.3, uc011xpx.4
UCSC ID: ENSMUST00000026461.8
RefSeq Accession: NM_008921
Protein: Q5FW94

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.