Mouse Gene Pax9 (ENSMUST00000001538.9) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus paired box 9 (Pax9), mRNA. (from RefSeq NM_011041) RefSeq Summary (NM_011041): This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. Mice lacking this gene exhibit impaired development of organs, musculature and the skeleton, including absent and abnormally developed teeth, and neonatal lethality. Mutations in the human gene are associated with selective tooth agenesis-3. [provided by RefSeq, Sep 2015]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENSMUST00000001538.9 Gencode Gene: ENSMUSG00000001497.18 Transcript (Including UTRs) Position: mm10 chr12:56,695,639-56,712,822 Size: 17,184 Total Exon Count: 4 Strand: + Coding Region Position: mm10 chr12:56,695,861-56,709,907 Size: 14,047 Coding Exon Count: 4
ModBase Predicted Comparative 3D Structure on Q3V1K1
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Orthologous Genes in Other Species
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Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0003677 DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding
Biological Process: GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006366 transcription from RNA polymerase II promoter GO:0007275 multicellular organism development GO:0007492 endoderm development GO:0009887 animal organ morphogenesis GO:0042476 odontogenesis GO:0042481 regulation of odontogenesis GO:0045892 negative regulation of transcription, DNA-templated GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0060325 face morphogenesis GO:0071363 cellular response to growth factor stimulus
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