Mouse Gene Pax7 (ENSMUST00000030508.13) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus paired box 7 (Pax7), mRNA. (from RefSeq NM_011039)
Gencode Transcript: ENSMUST00000030508.13
Gencode Gene: ENSMUSG00000028736.13
Transcript (Including UTRs)
   Position: mm10 chr4:139,737,062-139,833,528 Size: 96,467 Total Exon Count: 9 Strand: -
Coding Region
   Position: mm10 chr4:139,740,787-139,832,911 Size: 92,125 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-20

+  Sequence and Links to Tools and Databases
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-  Comments and Description Text from UniProtKB
  ID: PAX7_MOUSE
DESCRIPTION: RecName: Full=Paired box protein Pax-7;
FUNCTION: Probable transcription factor. May have a role in myogenesis.
SUBUNIT: Can bind to DNA as a heterodimer with PAX3. Interacts with DAXX (By similarity).
SUBCELLULAR LOCATION: Nucleus.
DEVELOPMENTAL STAGE: Expressed specifically during the development of the nervous and muscular system.
SIMILARITY: Belongs to the paired homeobox family.
SIMILARITY: Contains 1 homeobox DNA-binding domain.
SIMILARITY: Contains 1 paired domain.

+  Comparative Toxicogenomics Database (CTD)
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -288.10617-0.467 Picture PostScript Text
3' UTR -1283.023725-0.344 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR017970 - Homeobox_CS
IPR001356 - Homeodomain
IPR009057 - Homeodomain-like
IPR001523 - Paired_dom
IPR022106 - Pax7
IPR011991 - WHTH_trsnscrt_rep_DNA-bd

Pfam Domains:
PF00046 - Homeobox domain
PF00292 - 'Paired box' domain
PF05920 - Homeobox KN domain
PF12360 - Paired box protein 7

SCOP Domains:
46689 - Homeodomain-like

ModBase Predicted Comparative 3D Structure on P47239
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD Ensembl  
Protein SequenceProtein Sequence Protein Sequence  
AlignmentAlignment Alignment  

+  Gene Ontology (GO) Annotations with Structured Vocabulary
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-  Descriptions from all associated GenBank mRNAs
  AK133693 - Mus musculus adult male pituitary gland cDNA, RIKEN full-length enriched library, clone:5330440B08 product:paired box gene 7, full insert sequence.
AF254422 - Mus musculus paired box transcription factor PAX7 (Pax7) mRNA, complete cds.
BC156884 - Synthetic construct Mus musculus clone IMAGE:100062729, MGC:190944 paired box gene 7 (Pax7) mRNA, encodes complete protein.
BC156072 - Synthetic construct Mus musculus clone IMAGE:100062368, MGC:190857 paired box gene 7 (Pax7) mRNA, encodes complete protein.
U20792 - Mus musculus Pax7 mRNA, partial cds.

+  Other Names for This Gene
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-  Gene Model Information
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+  Methods, Credits, and Use Restrictions
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