ID:SCMC1_MOUSE DESCRIPTION: RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-1; AltName: Full=Small calcium-binding mitochondrial carrier protein 1; AltName: Full=Solute carrier family 25 member 24; FUNCTION: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (By similarity). SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity). SIMILARITY: Belongs to the mitochondrial carrier family. SIMILARITY: Contains 4 EF-hand domains. SIMILARITY: Contains 3 Solcar repeats.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00153 - Mitochondrial carrier protein PF13202 - EF hand PF13405 - EF-hand domain PF13499 - EF-hand domain pair PF13833 - EF-hand domain pair
SCOP Domains: 63446 - Type I dockerin domain 47473 - EF-hand 69318 - Integrin alpha N-terminal domain 81508 - Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 103506 - Mitochondrial carrier
ModBase Predicted Comparative 3D Structure on Q8BMD8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005347 ATP transmembrane transporter activity GO:0005509 calcium ion binding GO:0015217 ADP transmembrane transporter activity GO:0046872 metal ion binding