Mouse Gene Slc25a31 (ENSMUST00000091184.9) from GENCODE VM33
  Description: Mus musculus solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 (Slc25a31), mRNA. (from RefSeq NM_178386)
Gencode Transcript: ENSMUST00000091184.9
Gencode Gene: ENSMUSG00000069041.9
Transcript (Including UTRs)
   Position: mm39 chr3:40,663,285-40,680,527 Size: 17,243 Total Exon Count: 6 Strand: +
Coding Region
   Position: mm39 chr3:40,663,422-40,679,499 Size: 16,078 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-16 04:06:27

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:40,663,285-40,680,527)mRNA (may differ from genome)Protein (320 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: ADT4_MOUSE
DESCRIPTION: RecName: Full=ADP/ATP translocase 4; AltName: Full=ADP,ATP carrier protein 4; AltName: Full=Adenine nucleotide translocator 4; Short=ANT 4; AltName: Full=Solute carrier family 25 member 31; AltName: Full=Sperm flagellar energy carrier protein;
FUNCTION: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity). Cell projection, cilium, flagellum (By similarity). Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region (By similarity).
SIMILARITY: Belongs to the mitochondrial carrier family.
SIMILARITY: Contains 3 Solcar repeats.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -41.30137-0.301 Picture PostScript Text
3' UTR -212.201028-0.206 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002113 - Aden_trnslctor
IPR002067 - Mit_carrier
IPR018108 - Mitochondrial_sb/sol_carrier
IPR023395 - Mt_carrier_dom

Pfam Domains:
PF00153 - Mitochondrial carrier protein

ModBase Predicted Comparative 3D Structure on Q3V132
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0022857 transmembrane transporter activity

Biological Process:
GO:0006839 mitochondrial transport
GO:0055085 transmembrane transport

Cellular Component:
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005929 cilium
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031514 motile cilium
GO:0042995 cell projection


-  Descriptions from all associated GenBank mRNAs
  AK006599 - Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:1700034J06 product:similar to ADP,ATP CARRIER PROTEIN, HEART/SKELETAL MUSCLE ISOFORM T1 (ADP/ATP TRANSLOCASE 1) (ADENINE NUCLEOTIDE TRANSLOCATOR 1) (ANT 1) [Homo sapiens], full insert sequence.
AK132722 - Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4922503A02 product:similar to ADP-ATP translocator [Ethmostigmus rubripes], full insert sequence.
AY550241 - Mus musculus sperm flagellar energy carrier protein (Sfec) mRNA, complete cds.
BC050810 - Mus musculus solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31, mRNA (cDNA clone MGC:58785 IMAGE:6772660), complete cds.
BC139243 - Mus musculus solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31, mRNA (cDNA clone MGC:170870 IMAGE:8862265), complete cds.
BC139245 - Mus musculus solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31, mRNA (cDNA clone MGC:170872 IMAGE:8862267), complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: Aac4, ADT4_MOUSE, Ant4, ENSMUST00000091184.1, ENSMUST00000091184.2, ENSMUST00000091184.3, ENSMUST00000091184.4, ENSMUST00000091184.5, ENSMUST00000091184.6, ENSMUST00000091184.7, ENSMUST00000091184.8, NM_178386, Q3V132, Q80W28, Sfec, uc008pbi.1, uc008pbi.2, uc008pbi.3, uc008pbi.4
UCSC ID: ENSMUST00000091184.9
RefSeq Accession: NM_178386
Protein: Q3V132 (aka ADT4_MOUSE)

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.