ID:PAX1_MOUSE DESCRIPTION: RecName: Full=Paired box protein Pax-1; FUNCTION: This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column. SUBCELLULAR LOCATION: Nucleus. DISEASE: Note=Undulated (un) homozygous mice exhibits vertebral malformations along the entire rostro-caudal axis. This is due to a single mutation in the paired box region. SIMILARITY: Contains 1 paired domain. SEQUENCE CAUTION: Sequence=AAA37793.1; Type=Erroneous gene model prediction; Sequence=AAA39888.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
ModBase Predicted Comparative 3D Structure on P09084
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.