Mouse Gene Prrx2 (ENSMUST00000041659.6) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus paired related homeobox 2 (Prrx2), mRNA. (from RefSeq NM_009116)
Gencode Transcript: ENSMUST00000041659.6
Gencode Gene: ENSMUSG00000039476.13
Transcript (Including UTRs)
   Position: mm10 chr2:30,845,059-30,881,251 Size: 36,193 Total Exon Count: 4 Strand: +
Coding Region
   Position: mm10 chr2:30,845,435-30,880,930 Size: 35,496 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-20

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr2:30,845,059-30,881,251)mRNA (may differ from genome)Protein (247 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
MGIPubMedStanford SOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: A2APZ7_MOUSE
DESCRIPTION: SubName: Full=Paired mesoderm homeobox protein 2; SubName: Full=Paired related homeobox 2;
SUBCELLULAR LOCATION: Nucleus (By similarity).
SIMILARITY: Contains 1 homeobox DNA-binding domain.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -177.60376-0.472 Picture PostScript Text
3' UTR -111.20321-0.346 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR017970 - Homeobox_CS
IPR001356 - Homeodomain
IPR009057 - Homeodomain-like
IPR003654 - OAR_dom

Pfam Domains:
PF00046 - Homeobox domain
PF03826 - OAR domain

SCOP Domains:
46689 - Homeodomain-like

ModBase Predicted Comparative 3D Structure on A2APZ7
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD Ensembl  
Protein SequenceProtein Sequence Protein Sequence  
AlignmentAlignment Alignment  

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding

Biological Process:
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organism development

Cellular Component:
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  AK019971 - Mus musculus 8 days embryo whole body cDNA, RIKEN full-length enriched library, clone:5730524N22 product:paired related homeobox 2, full insert sequence.
X52875 - Mouse homeobox gene Prx2 mRNA.
BC137872 - Mus musculus paired related homeobox 2, mRNA (cDNA clone MGC:169496 IMAGE:8860891), complete cds.
BC137874 - Mus musculus paired related homeobox 2, mRNA (cDNA clone MGC:169498 IMAGE:8860893), complete cds.
X14572 - Mouse S8 mRNA containing homeo box.

-  Other Names for This Gene
  Alternate Gene Symbols: A2APZ7, A2APZ7_MOUSE, NM_009116, RP23-221O14.5-002, uc008jcy.1, uc008jcy.2, uc008jcy.3
UCSC ID: uc008jcy.3
RefSeq Accession: NM_009116
Protein: A2APZ7 CCDS: CCDS15888.1

+  Gene Model Information
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-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.