Mouse Gene Pax8 (ENSMUST00000028355.10) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus paired box 8 (Pax8), mRNA. (from RefSeq NM_011040)
RefSeq Summary (NM_011040): This gene encodes a member of a family of transcription factors that contain a characteristic N-terminal paired DNA-binding domain. The encoded protein is important for proper differentiation of the thyroid and the kidney. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Mar 2013].
Gencode Transcript: ENSMUST00000028355.10
Gencode Gene: ENSMUSG00000026976.15
Transcript (Including UTRs)
   Position: mm10 chr2:24,420,560-24,475,599 Size: 55,040 Total Exon Count: 12 Strand: -
Coding Region
   Position: mm10 chr2:24,421,548-24,475,097 Size: 53,550 Coding Exon Count: 11 

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Other SpeciesGO AnnotationsmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-20

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr2:24,420,560-24,475,599)mRNA (may differ from genome)Protein (457 aa)
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-  Comments and Description Text from UniProtKB
  ID: PAX8_MOUSE
DESCRIPTION: RecName: Full=Paired box protein Pax-8;
FUNCTION: Thought to encode a transcription factor. It may have a role in kidney cell differentiation. May play a regulatory role in mammalian development.
SUBUNIT: Interacts with WWTR1 (By similarity).
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Expressed in the developing excretory system and the thyroid gland.
SIMILARITY: Contains 1 paired domain.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  mRNA Secondary Structure of 3' and 5' UTRs
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+  Protein Domain and Structure Information
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+  Orthologous Genes in Other Species
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+  Gene Ontology (GO) Annotations with Structured Vocabulary
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+  Descriptions from all associated GenBank mRNAs
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-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
mmu05200 - Pathways in cancer
mmu05216 - Thyroid cancer

-  Other Names for This Gene
  Alternate Gene Symbols: NM_011040, P97342, Pax-8, PAX8_MOUSE, Q00288, Q6GU20, uc008ipb.1, uc008ipb.2, uc008ipb.3
UCSC ID: uc008ipb.3
RefSeq Accession: NM_011040
Protein: Q00288 (aka PAX8_MOUSE)
CCDS: CCDS15738.1

+  Gene Model Information
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+  Methods, Credits, and Use Restrictions
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