Mouse Gene Rax (ENSMUST00000025396.4) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus retina and anterior neural fold homeobox (Rax), mRNA. (from RefSeq NM_013833)
Gencode Transcript: ENSMUST00000025396.4
Gencode Gene: ENSMUSG00000024518.4
Transcript (Including UTRs)
   Position: mm10 chr18:65,934,636-65,939,089 Size: 4,454 Total Exon Count: 3 Strand: -
Coding Region
   Position: mm10 chr18:65,935,004-65,938,814 Size: 3,811 Coding Exon Count: 3 

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Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-20

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr18:65,934,636-65,939,089)mRNA (may differ from genome)Protein (342 aa)
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-  Comments and Description Text from UniProtKB
  ID: RX_MOUSE
DESCRIPTION: RecName: Full=Retinal homeobox protein Rx; AltName: Full=Retina and anterior neural fold homeobox protein;
FUNCTION: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter (By similarity).
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Expressed in the photoreceptor and inner nuclear layers.
DEVELOPMENTAL STAGE: Strongly expressed in anterior neural plate at E8.5, followed in optic sulci and ventral forebrain at E9.0, and in eye at E10.5 uniformly expressed in neuroretina at E15.5, and at later stages, expression decreases.
SIMILARITY: Belongs to the paired homeobox family. Bicoid subfamily.
SIMILARITY: Contains 1 homeobox DNA-binding domain.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  mRNA Secondary Structure of 3' and 5' UTRs
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+  Protein Domain and Structure Information
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologGenome BrowserNo orthologNo ortholog
      
      
 RGDEnsemblEnsemblWormBase 
 Protein Sequence Protein Sequence  
 Alignment Alignment  

+  Gene Ontology (GO) Annotations with Structured Vocabulary
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-  Descriptions from all associated GenBank mRNAs
  AK053517 - Mus musculus 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130104K16 product:retina and anterior neural fold homeobox, full insert sequence.
BC058757 - Mus musculus retina and anterior neural fold homeobox, mRNA (cDNA clone MGC:68025 IMAGE:6492771), complete cds.
AF001906 - Mus musculus retinal homeobox protein (Rx) mRNA, complete cds.
U73177 - Mus musculus paired-type homeobox (rax) mRNA, complete cds.
AK133951 - Mus musculus 8 days embryo whole body cDNA, RIKEN full-length enriched library, clone:5730556B11 product:retina and anterior neural fold homeobox, full insert sequence.
BC024731 - Mus musculus retina and anterior neural fold homeobox, mRNA (cDNA clone MGC:35992 IMAGE:5366450), complete cds.
AK053732 - Mus musculus 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130303K03 product:retina and anterior neural fold homeobox, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_013833, O08748, O35602, Q6GT92, Rx, RX_MOUSE, uc008ffl.1, uc008ffl.2
UCSC ID: uc008ffl.2
RefSeq Accession: NM_013833
Protein: O35602 (aka RX_MOUSE)
CCDS: CCDS29311.1

+  Gene Model Information
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-  Methods, Credits, and Use Restrictions
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