Mouse Gene Phox2a (ENSMUST00000008090.10) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus paired-like homeobox 2a (Phox2a), mRNA. (from RefSeq NM_008887)
Gencode Transcript: ENSMUST00000008090.10
Gencode Gene: ENSMUSG00000007946.11
Transcript (Including UTRs)
   Position: mm10 chr7:101,818,313-101,822,726 Size: 4,414 Total Exon Count: 3 Strand: +
Coding Region
   Position: mm10 chr7:101,818,498-101,822,145 Size: 3,648 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-20

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:101,818,313-101,822,726)mRNA (may differ from genome)Protein (280 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
MGIPubMedStanford SOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: PHX2A_MOUSE
DESCRIPTION: RecName: Full=Paired mesoderm homeobox protein 2A; AltName: Full=Aristaless homeobox protein homolog; AltName: Full=PHOX2A homeodomain protein; AltName: Full=Paired-like homeobox 2A;
FUNCTION: May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype (By similarity).
SUBCELLULAR LOCATION: Nucleus (By similarity).
SIMILARITY: Belongs to the paired homeobox family.
SIMILARITY: Contains 1 homeobox DNA-binding domain.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  mRNA Secondary Structure of 3' and 5' UTRs
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+  Protein Domain and Structure Information
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
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Protein SequenceProtein Sequence    
AlignmentAlignment    

+  Gene Ontology (GO) Annotations with Structured Vocabulary
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-  Descriptions from all associated GenBank mRNAs
  X75014 - M.musculus Phox2 mRNA for homeodomain protein.
BC172615 - Synthetic construct Mus musculus clone IMAGE:100069423, MGC:199325 paired-like homeobox 2a (Phox2a) mRNA, encodes complete protein.
BC172722 - Synthetic construct Mus musculus clone IMAGE:100069530, MGC:199432 paired-like homeobox 2a (Phox2a) mRNA, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: Arix, NM_008887, Phox2, PHX2A_MOUSE, Pmx2, Pmx2a, Q62066, uc009ipe.1, uc009ipe.2
UCSC ID: uc009ipe.2
RefSeq Accession: NM_008887
Protein: Q62066 (aka PHX2A_MOUSE)
CCDS: CCDS21514.1

+  Gene Model Information
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-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.