Mouse Gene Pax2 (ENSMUST00000004340.10) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Nucleus (By similarity). (from UniProt G3X8Q7)
Gencode Transcript: ENSMUST00000004340.10
Gencode Gene: ENSMUSG00000004231.15
Transcript (Including UTRs)
   Position: mm10 chr19:44,757,394-44,837,871 Size: 80,478 Total Exon Count: 11 Strand: +
Coding Region
   Position: mm10 chr19:44,757,394-44,836,027 Size: 78,634 Coding Exon Count: 11 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Data last updated at UCSC: 2019-09-20

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr19:44,757,394-44,837,871)mRNA (may differ from genome)Protein (416 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold

-  Comments and Description Text from UniProtKB
DESCRIPTION: SubName: Full=Paired box gene 2; SubName: Full=Paired box protein Pax-2;
SUBCELLULAR LOCATION: Nucleus (By similarity).
SIMILARITY: Contains 1 paired domain.

-  Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -628.001844-0.341 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR009057 - Homeodomain-like
IPR001523 - Paired_dom
IPR022130 - Pax2_C
IPR011991 - WHTH_trsnscrt_rep_DNA-bd

Pfam Domains:
PF00292 - 'Paired box' domain
PF12403 - Paired-box protein 2 C terminal

SCOP Domains:
46689 - Homeodomain-like
46785 - "Winged helix" DNA-binding domain

ModBase Predicted Comparative 3D Structure on G3X8Q7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003677 DNA binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organism development

Cellular Component:
GO:0005634 nucleus

-  Descriptions from all associated GenBank mRNAs
  LF204748 - JP 2014500723-A/12251: Polycomb-Associated Non-Coding RNAs.
BC150484 - Mus musculus paired box gene 2, mRNA (cDNA clone MGC:161329 IMAGE:40142579), complete cds.
BC148232 - Mus musculus paired box gene 2, mRNA (cDNA clone MGC:161328 IMAGE:40142573), complete cds.
MA440325 - JP 2018138019-A/12251: Polycomb-Associated Non-Coding RNAs.
LF201797 - JP 2014500723-A/9300: Polycomb-Associated Non-Coding RNAs.
BC031455 - Mus musculus, Similar to proline rich protein 2, clone IMAGE:4235142, mRNA.
LF258365 - JP 2014500723-A/65868: Polycomb-Associated Non-Coding RNAs.
MA437374 - JP 2018138019-A/9300: Polycomb-Associated Non-Coding RNAs.
MA493942 - JP 2018138019-A/65868: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: BC148232, G3X8Q7, G3X8Q7_MOUSE, mCG_142475, uc289sdj.1
UCSC ID: uc289sdj.1
RefSeq Accession: NM_001368746
Protein: G3X8Q7

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.