Mouse Gene Slc25a21 (ENSMUST00000044634.11) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 (Slc25a21), transcript variant 1, mRNA. (from RefSeq NM_172577)
Gencode Transcript: ENSMUST00000044634.11
Gencode Gene: ENSMUSG00000035472.14
Transcript (Including UTRs)
   Position: mm10 chr12:56,712,634-57,197,472 Size: 484,839 Total Exon Count: 10 Strand: -
Coding Region
   Position: mm10 chr12:56,713,813-57,196,939 Size: 483,127 Coding Exon Count: 10 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsPathwaysOther NamesModel Information
Data last updated at UCSC: 2019-09-20

+  Sequence and Links to Tools and Databases
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-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Mitochondrial 2-oxodicarboxylate carrier; AltName: Full=Solute carrier family 25 member 21;
FUNCTION: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate (By similarity).
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity).
SIMILARITY: Belongs to the mitochondrial carrier family.
SIMILARITY: Contains 3 Solcar repeats.

+  Comparative Toxicogenomics Database (CTD)
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -185.80533-0.349 Picture PostScript Text
3' UTR -220.401179-0.187 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

+  Protein Domain and Structure Information
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserGenome BrowserNo ortholog
Gene Details    Gene Details
Gene Sorter    Gene Sorter
Protein SequenceProtein Sequence Protein SequenceProtein Sequence 
AlignmentAlignment AlignmentAlignment 

+  Gene Ontology (GO) Annotations with Structured Vocabulary
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-  Biochemical and Signaling Pathways
  Reactome (by CSHL, EBI, and GO)

Protein Q8BZ09 (Reactome details) participates in the following event(s):

R-MMU-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]
R-MMU-71064 Lysine catabolism
R-MMU-6788656 Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism
R-MMU-71291 Metabolism of nitrogenous molecules
R-MMU-1430728 Metabolism

-  Other Names for This Gene
  Alternate Gene Symbols: NM_172577, Odc, ODC_MOUSE, Q8BY72, Q8BZ09, uc007npj.1, uc007npj.2
UCSC ID: uc007npj.2
RefSeq Accession: NM_172577
Protein: Q8BZ09 (aka ODC_MOUSE)
CCDS: CCDS25925.1

+  Gene Model Information
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-  Methods, Credits, and Use Restrictions
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