ID:PAX5_MOUSE DESCRIPTION: RecName: Full=Paired box protein Pax-5; AltName: Full=B-cell-specific transcription factor; Short=BSAP; FUNCTION: May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. SUBUNIT: Interacts with ETS1, altering its DNA-binding properties (By similarity). Interacts with DAXX and TLE4. Binds DNA as a monomer. INTERACTION: Q9UER7:DAXX (xeno); NbExp=4; IntAct=EBI-296260, EBI-77321; SUBCELLULAR LOCATION: Nucleus. DEVELOPMENTAL STAGE: Expressed at early B-cell differentiation, in the developing CNS and in adult testis. PTM: O-glycosylated (Probable). SIMILARITY: Contains 1 paired domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Press "+" in the title bar above to open this section.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
