Mouse Gene Slc25a35 (ENSMUST00000102606.9) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus solute carrier family 25, member 35 (Slc25a35), mRNA. (from RefSeq NM_028048)
Gencode Transcript: ENSMUST00000102606.9
Gencode Gene: ENSMUSG00000018740.14
Transcript (Including UTRs)
   Position: mm10 chr11:68,968,131-68,972,516 Size: 4,386 Total Exon Count: 5 Strand: +
Coding Region
   Position: mm10 chr11:68,968,663-68,972,123 Size: 3,461 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-20

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:68,968,131-68,972,516)mRNA (may differ from genome)Protein (300 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: S2535_MOUSE
DESCRIPTION: RecName: Full=Solute carrier family 25 member 35;
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity).
SIMILARITY: Belongs to the mitochondrial carrier family.
SIMILARITY: Contains 3 Solcar repeats.
SEQUENCE CAUTION: Sequence=AAH04569.1; Type=Erroneous initiation; Sequence=CAI25535.1; Type=Erroneous gene model prediction;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -99.80532-0.188 Picture PostScript Text
3' UTR -93.24393-0.237 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR018108 - Mitochondrial_sb/sol_carrier
IPR023395 - Mt_carrier_dom

Pfam Domains:
PF00153 - Mitochondrial carrier protein

SCOP Domains:
103506 - Mitochondrial carrier

ModBase Predicted Comparative 3D Structure on Q5SWT3
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGDEnsemblEnsembl  
Protein SequenceProtein Sequence Protein Sequence  
AlignmentAlignment Alignment  

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0022857 transmembrane transporter activity

Biological Process:
GO:0006839 mitochondrial transport
GO:0055085 transmembrane transport

Cellular Component:
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  LF198579 - JP 2014500723-A/6082: Polycomb-Associated Non-Coding RNAs.
AK171131 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630226K08 product:weakly similar to Hypothetical mitochondrial energy transfer proteins [Mus musculus], full insert sequence.
AK007453 - Mus musculus 10 day old male pancreas cDNA, RIKEN full-length enriched library, clone:1810012H11 product:hypothetical Mitochondrial energy transfer proteins (carrier protein) containing protein, full insert sequence.
AK157873 - Mus musculus adult inner ear cDNA, RIKEN full-length enriched library, clone:F930002I03 product:hypothetical Mitochondrial substrate carrier containing protein, full insert sequence.
AK035739 - Mus musculus adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530097O21 product:RAN guanine nucleotide release factor, full insert sequence.
BC019996 - Mus musculus solute carrier family 25, member 35, mRNA (cDNA clone MGC:28559 IMAGE:4207271), complete cds.
BC004569 - Mus musculus solute carrier family 25, member 35, mRNA (cDNA clone IMAGE:3586188), partial cds.
AK201153 - Mus musculus cDNA, clone:Y1G0137D15, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000018884, based on BLAT search.
AK181743 - Mus musculus cDNA, clone:Y0G0119E13, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000018884, based on BLAT search.
AK186841 - Mus musculus cDNA, clone:Y0G0138P10, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000018884, based on BLAT search.
AK189727 - Mus musculus cDNA, clone:Y0G0150E03, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000018884, based on BLAT search.
LF228298 - JP 2014500723-A/35801: Polycomb-Associated Non-Coding RNAs.
LF228299 - JP 2014500723-A/35802: Polycomb-Associated Non-Coding RNAs.
MA434156 - JP 2018138019-A/6082: Polycomb-Associated Non-Coding RNAs.
MA463875 - JP 2018138019-A/35801: Polycomb-Associated Non-Coding RNAs.
MA463876 - JP 2018138019-A/35802: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_028048, Q3TBP2, Q5SWT3, Q99KM5, Q9D913, S2535_MOUSE, uc007jop.1, uc007jop.2
UCSC ID: uc007jop.2
RefSeq Accession: NM_028048
Protein: Q5SWT3 (aka S2535_MOUSE)
CCDS: CCDS24874.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.