Mouse Gene Slc25a45 (ENSMUST00000125114.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity). (from UniProt Q8CFJ7)
Gencode Transcript: ENSMUST00000125114.7
Gencode Gene: ENSMUSG00000024818.15
Transcript (Including UTRs)
Position: mm10 chr19:5,877,817-5,885,766 Size: 7,950 Total Exon Count: 5 Strand: +
Coding Region
Position: mm10 chr19:5,878,655-5,884,644 Size: 5,990 Coding Exon Count: 5
Data last updated at UCSC: 2019-09-20
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: S2545_MOUSE
DESCRIPTION: RecName: Full=Solute carrier family 25 member 45;
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity).SIMILARITY: Belongs to the mitochondrial carrier family.SIMILARITY: Contains 3 Solcar repeats.SEQUENCE CAUTION: Sequence=AAH22156.1; Type=Erroneous initiation; Sequence=BAE42082.1; Type=Frameshift; Positions=259;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR002067 - Mit_carrier
IPR018108 - Mitochondrial_sb/sol_carrier
IPR023395 - Mt_carrier_dom
Pfam Domains: PF00153 - Mitochondrial carrier protein
SCOP Domains: 103506 - Mitochondrial carrier
ModBase Predicted Comparative 3D Structure on Q8CFJ7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK133879 - Mus musculus 8 days embryo whole body cDNA, RIKEN full-length enriched library, clone:5730478M19 product:hypothetical Mitochondrial substrate carrier containing protein, full insert sequence.AK155754 - Mus musculus B6-derived CD11 +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F730216B10 product:hypothetical Adenine nucleotide translocator 1/Mitochondrial carrier protein/Mitochondrial substrate carrier containing protein, full insert sequence.AK169876 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630002E17 product:hypothetical Adenine nucleotide translocator 1/Mitochondrial carrier protein/Mitochondrial substrate carrier containing protein, full insert sequence.AK170869 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630206H20 product:hypothetical Mitochondrial carrier protein/Mitochondrial substrate carrier containing protein, full insert sequence.BC037680 - Mus musculus solute carrier family 25, member 45, mRNA (cDNA clone MGC:47212 IMAGE:3481846), complete cds.BC022156 - Mus musculus solute carrier family 25, member 45, mRNA (cDNA clone IMAGE:5133804), partial cds.
Other Names for This Gene
Alternate Gene Symbols: AK133879, Q3TC75, Q3UZE9, Q8CFJ7, Q8VBZ7, S2545_MOUSE, uc008gfr.1, uc008gfr.2UCSC ID: uc008gfr.2RefSeq Accession: NM_134154
Protein: Q8CFJ7
(aka S2545_MOUSE)
Gene Model Information
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.