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Gencode Genes

UBE2W (ENST00000517608.5) at chr8:73786220-73878910 - Accepts ubiquitin from the E1 complex and catalyzes its  covalent attachment to other proteins. Catalyzes  monoubiquitination. Involved in degradation of misfolded chaperone  substrates by mediating monoubiquitination of STUB1/CHIP, leading  to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and  restriction of the length of ubiquitin chain attached to  STUB1/CHIP substrates by ATXN3. After UV irradiation, but not  after mitomycin-C (MMC) treatment, acts as a specific E2  ubiquitin-conjugating enzyme for the Fanconi anemia complex by  associating with E3 ubiquitin-protein ligase FANCL and catalyzing  monoubiquitination of FANCD2, a key step in the DNA damage  pathway. In vitro catalyzes 'Lys-11'-linked polyubiquitination. (from UniProt Q96B02)
UBE2W (ENST00000651945.1) at chr8:73792363-73878862 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 1, mRNA. (from RefSeq NM_001001481)
UBE2W (ENST00000650817.1) at chr8:73786220-73878910 - ubiquitin conjugating enzyme E2 W (from HGNC UBE2W)
UBE2W (ENST00000602593.6) at chr8:73786219-73878862 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 2, mRNA. (from RefSeq NM_018299)
UBE2W (ENST00000523278.5) at chr8:73780097-73830474 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 3, mRNA. (from RefSeq NM_001271015)
UBE2W (ENST00000519277.5) at chr8:73793824-73878854 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 5, non-coding RNA. (from RefSeq NR_073120)
UBE2W (ENST00000519255.2) at chr8:73794042-73878860 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 4, non-coding RNA. (from RefSeq NR_073119)
UBE2W (ENST00000422906.6) at chr8:73790605-73878875 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 6, non-coding RNA. (from RefSeq NR_073121)
UBE2W (ENST00000419880.7) at chr8:73792363-73878909 - ubiquitin conjugating enzyme E2 W (from HGNC UBE2W)
FANCL (ENST00000233741.8) at chr2:58159247-58241350 - Homo sapiens FA complementation group L (FANCL), transcript variant 2, mRNA. (from RefSeq NM_018062)
FANCL (ENST00000402135.7) at chr2:58159247-58241350 - Homo sapiens FA complementation group L (FANCL), transcript variant 1, mRNA. (from RefSeq NM_001114636)
STUB1 (ENST00000565677.5) at chr16:680224-682746 - Homo sapiens STIP1 homology and U-box containing protein 1 (STUB1), transcript variant 2, mRNA. (from RefSeq NM_001293197)
STUB1 (ENST00000219548.9) at chr16:680410-682801 - Homo sapiens STIP1 homology and U-box containing protein 1 (STUB1), transcript variant 1, mRNA. (from RefSeq NM_005861)
STUB1 (ENST00000564370.5) at chr16:681037-682496 - E3 ubiquitin-protein ligase which targets misfolded  chaperone substrates towards proteasomal degradation. Collaborates  with ATXN3 in the degradation of misfolded chaperone substrates:  ATXN3 restricting the length of ubiquitin chain attached to  STUB1/CHIP substrates and preventing further chain extension.  Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the  activity of several chaperone complexes, including Hsp70, Hsc70  and Hsp90. Mediates transfer of non-canonical short ubiquitin  chains to HSPA8 that have no effect on HSPA8 degradation. Mediates  polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41',  'Lys-61' and 'Lys-81', thereby playing a role in base-excision  repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF-  BP1-dependent monoubiquitination and leading to POLB-degradation  by the proteasome. Mediates polyubiquitination of CYP3A4.  Ubiquitinates EPHA2 and may regulate the receptor stability and  activity through proteasomal degradation. (from UniProt Q9UNE7)
ATXN3 (ENST00000502250.5) at chr14:92063881-92106582 - Homo sapiens ataxin 3 (ATXN3), transcript variant u, mRNA. (from RefSeq NM_001164780)
ATXN3 (ENST00000503767.5) at chr14:92064094-92106600 - Homo sapiens ataxin 3 (ATXN3), transcript variant ad, mRNA. (from RefSeq NM_001127696)
ATXN3 (ENST00000340660.10) at chr14:92064094-92106610 - Homo sapiens ataxin 3 (ATXN3), transcript variant h, mRNA. (from RefSeq NM_030660)
ATXN3 (ENST00000644486.2) at chr14:92058552-92106582 - Homo sapiens ataxin 3 (ATXN3), transcript variant p, non-coding RNA. (from RefSeq NR_028461)
ATXN3 (ENST00000532032.5) at chr14:92070745-92106562 - Deubiquitinating enzyme involved in protein homeostasis  maintenance, transcription, cytoskeleton regulation, myogenesis  and degradation of misfolded chaperone substrates. Binds long  polyubiquitin chains and trims them, while it has weak or no  activity against chains of 4 or less ubiquitins. Involved in  degradation of misfolded chaperone substrates via its interaction  with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and  restricts the length of ubiquitin chain attached to STUB1/CHIP  substrates and preventing further chain extension. In response to  misfolded substrate ubiquitination, mediates deubiquitination of  monoubiquitinated STUB1/CHIP. Interacts with key regulators of  transcription and represses transcription: acts as a histone-  binding protein that regulates transcription. (from UniProt P54252)
FANCD2 (ENST00000431693.1) at chr3:10028620-10041562 - Required for maintenance of chromosomal stability.  Promotes accurate and efficient pairing of homologs during  meiosis. Involved in the repair of DNA double-strand breaks, both  by homologous recombination and single-strand annealing. May  participate in S phase and G2 phase checkpoint activation upon DNA  damage. Plays a role in preventing breakage and loss of  missegregating chromatin at the end of cell division, particularly  after replication stress. Required for the targeting, or  stabilization, of BLM to non-centromeric abnormal structures  induced by replicative stress. Promotes BRCA2/FANCD1 loading onto  damaged chromatin. May also be involved in B-cell immunoglobulin  isotype switching. (from UniProt Q9BXW9)
FANCD2 (ENST00000419585.5) at chr3:10026499-10101930 - Homo sapiens FA complementation group D2 (FANCD2), transcript variant 3, mRNA. (from RefSeq NM_001319984)
FANCD2 (ENST00000383807.5) at chr3:10026429-10101930 - Homo sapiens FA complementation group D2 (FANCD2), transcript variant 2, mRNA. (from RefSeq NM_001018115)
FANCD2 (ENST00000287647.7) at chr3:10026414-10099660 - Homo sapiens FA complementation group D2 (FANCD2), transcript variant 1, mRNA. (from RefSeq NM_033084)
UBE2WP1 (ENST00000362030.3) at chr1:96418594-96418933 - ubiquitin conjugating enzyme E2 W pseudogene 1 (from HGNC UBE2WP1)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_001271015.1 at chr8:73780097-73878910
NM_001001481.2 at chr8:73786220-73878910
NM_018299.4 at chr8:73786220-73878910
NR_073120.1 at chr8:73786220-73878910
NR_073119.1 at chr8:73786220-73878910
NR_073121.1 at chr8:73786220-73878910

NCBI RefSeq and Ensembl transcripts from the MANE Project (v0.6)

UBE2W at chr8:73786219-73878862

RefSeq Genes

UBE2W at chr8:73786219-73878862 - (NM_018299) ubiquitin-conjugating enzyme E2 W isoform 2
UBE2W at chr8:73786219-73878862 - (NM_001001481) ubiquitin-conjugating enzyme E2 W isoform 1
UBE2W at chr8:73780096-73878862 - (NM_001271015) ubiquitin-conjugating enzyme E2 W isoform 3
UBE2W at chr8:73786219-73878862 - (NR_073121) 
UBE2W at chr8:73786219-73878862 - (NR_073120) 
UBE2W at chr8:73786219-73878862 - (NR_073119) 

NCBI RefSeq other annotations (not NM_*, NR_*, XM_*, XR_*, NP_* or YP_*)

UBE2WP1 at chr1:96418592-96418913

Non-Human RefSeq Genes

UBE2W at chr8:73793270-73878831 - (NM_001243317) ubiquitin-conjugating enzyme E2 W
UBE2W at chr8:73793141-73878838 - (NM_001266510) ubiquitin-conjugating enzyme E2 W
ube2w at chr8:73805635-73878839 - (NM_001165151) probable ubiquitin-conjugating enzyme E2 W
UBE2W at chr8:73793173-73878837 - (NM_001199481) ubiquitin-conjugating enzyme E2 W
UBE2W at chr8:73788130-73878860 - (NM_001099122) ubiquitin-conjugating enzyme E2 W
Ube2w at chr8:73792196-73878862 - (NM_001271017) ubiquitin-conjugating enzyme E2 W isoform 3
Ube2w at chr8:73805648-73878862 - (NM_001271016) ubiquitin-conjugating enzyme E2 W isoform 2
Ube2w at chr8:73792196-73878862 - (NM_025773) ubiquitin-conjugating enzyme E2 W isoform 1
Ube2w at chr8:73792196-73878862 - (NR_073122) 
ube2w at chr8:73793570-73878829 - (NM_001016132) ubiquitin-conjugating enzyme E2 W

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878862
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878862
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

UBE2W at chr8:73786220-73878910
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

UBE2W at chr8:73780097-73830474
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73786220-73878910
UBE2W at chr8:73790605-73878875
UBE2W at chr8:73792360-73878825
UBE2W at chr8:73792363-73878909
UBE2W at chr8:73793824-73878854
UBE2W at chr8:73794042-73878860

Retroposed Genes V9, Including Pseudogenes

UBE2W at chr7:45866735-45867961 - (NR_073120.1-208)
UBE2W at chr15:92311049-92311721 - (AK295792.1-3)
UBE2W at chr7:45866735-45867961 - (NR_073120.1-208)
UBE2W at chr15:92311049-92311721 - (AK295792.1-3)
UBE2W at chr1:96418570-96422672 - (NM_001001481.2-13)
UBE2W at chr21:38216857-38217264 - (AK295792.1-4)
UBE2W at chr1:96418570-96422672 - (NM_001001481.2-13)
UBE2W at chr21:38216857-38217264 - (AK295792.1-4)

International Knockout Mouse Consortium Genes Mapped to Human Genome

Ube2w_40454 at chr8:73790605-73878875

Human Aligned mRNA Search Results

BC010900 - Homo sapiens ubiquitin-conjugating enzyme E2W (putative), mRNA (cDNA clone MGC:13396 IMAGE:4081461), complete cds.
BC016326 - Homo sapiens ubiquitin-conjugating enzyme E2W (putative), mRNA (cDNA clone MGC:23711 IMAGE:4093131), complete cds.

Human Unaligned mRNA Search Results

NR_073121 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 6, non-coding RNA.
NR_073120 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 5, non-coding RNA.
NR_073119 - Homo sapiens ubiquitin conjugating enzyme E2 W (UBE2W), transcript variant 4, non-coding RNA.

Non-Human Aligned mRNA Search Results

BC020124 - Mus musculus ubiquitin-conjugating enzyme E2W (putative), mRNA (cDNA clone MGC:28304 IMAGE:4012785), complete cds.
BC146162 - Bos taurus ubiquitin-conjugating enzyme E2W (putative), mRNA (cDNA clone MGC:165835 IMAGE:8974697), complete cds.
BT077286 - Caligus rogercresseyi clone crog-evp-519-152 Probable ubiquitin-conjugating enzyme E2 W putative mRNA, complete cds.
JU320318 - TSA: Macaca mulatta Mamu_512144 mRNA sequence.
JU470972 - TSA: Macaca mulatta Mamu_365431 mRNA sequence.
JV047546 - TSA: Macaca mulatta Mamu_428854 mRNA sequence.
BT074100 - Oncorhynchus mykiss clone omyk-evo-511-081 Probable ubiquitin-conjugating enzyme E2 W putative mRNA, complete cds.