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Gencode Genes

SSTR2 (ENST00000357585.4) at chr17:73165010-73176633 - Homo sapiens somatostatin receptor 2 (SSTR2), mRNA. (from RefSeq NM_001050)
SSTR2 (ENST00000579323.5) at chr17:73165012-73169311 - somatostatin receptor 2 (from HGNC SSTR2)
TCF4 (ENST00000636400.2) at chr18:55222334-55589778 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
TCF4 (ENST00000626584.2) at chr18:55228225-55422356 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
TCF4 (ENST00000616053.4) at chr18:55222331-55588629 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
TCF4 (ENST00000570177.6) at chr18:55227984-55402240 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
TCF4 (ENST00000567880.5) at chr18:55227911-55587116 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
TCF4 (ENST00000566279.5) at chr18:55227911-55588617 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
TCF4 (ENST00000565018.6) at chr18:55227911-55589777 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
TCF4 (ENST00000564999.5) at chr18:55226646-55588625 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
TCF4 (ENST00000537856.7) at chr18:55227849-55401757 - Transcription factor that binds to the immunoglobulin  enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal  differentiation. Activates transcription by binding to the E box  (5'-CANNTG-3'). Binds to the E-box present in the somatostatin  receptor 2 initiator element (SSTR2-INR) to activate transcription  (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or  5'-CCANNTGG-3'. (from UniProt P15884)
SHANK1 (ENST00000359082.3) at chr19:50661965-50716919 - Seems to be an adapter protein in the postsynaptic  density (PSD) of excitatory synapses that interconnects receptors  of the postsynaptic membrane including NMDA-type and metabotropic  glutamate receptors via complexes with GKAP/PSD-95 and Homer,  respectively, and the actin-based cytoskeleton. Plays a role in  the structural and functional organization of the dendritic spine  and synaptic junction. (from UniProt Q9Y566)
SHANK1 (ENST00000391813.5) at chr19:50661827-50689404 - Seems to be an adapter protein in the postsynaptic  density (PSD) of excitatory synapses that interconnects receptors  of the postsynaptic membrane including NMDA-type and metabotropic  glutamate receptors via complexes with GKAP/PSD-95 and Homer,  respectively, and the actin-based cytoskeleton. Plays a role in  the structural and functional organization of the dendritic spine  and synaptic junction. (from UniProt Q9Y566)
SSTR3 (ENST00000610913.2) at chr22:37204237-37212477 - Homo sapiens somatostatin receptor 3 (SSTR3), transcript variant 1, mRNA. (from RefSeq NM_001051)
SSTR3 (ENST00000617123.1) at chr22:37206480-37210965 - Homo sapiens somatostatin receptor 3 (SSTR3), transcript variant 2, mRNA. (from RefSeq NM_001278687)
TCF4 (ENST00000570287.6) at chr18:55226644-55321986 - Homo sapiens transcription factor 4 (TCF4), transcript variant 20, mRNA. (from RefSeq NM_001348214)
TCF4 (ENST00000566286.5) at chr18:55227911-55588535 - Homo sapiens transcription factor 4 (TCF4), transcript variant 6, mRNA. (from RefSeq NM_001243230)
TCF4 (ENST00000564228.5) at chr18:55227911-55403714 - Homo sapiens transcription factor 4 (TCF4), transcript variant 14, mRNA. (from RefSeq NM_001306208)
TCF4 (ENST00000561992.5) at chr18:55227864-55422492 - Homo sapiens transcription factor 4 (TCF4), transcript variant 18, mRNA. (from RefSeq NM_001348212)
TCF4 (ENST00000561831.7) at chr18:55227878-55302626 - Homo sapiens transcription factor 4 (TCF4), transcript variant 22, mRNA. (from RefSeq NM_001348216)
TCF4 (ENST00000356073.8) at chr18:55222334-55588629 - Homo sapiens transcription factor 4 (TCF4), transcript variant 2, mRNA. (from RefSeq NM_003199)
TCF4 (ENST00000544241.6) at chr18:55227855-55403995 - Homo sapiens transcription factor 4 (TCF4), transcript variant 8, mRNA. (from RefSeq NM_001243232)
TCF4 (ENST00000543082.5) at chr18:55227689-55510772 - Homo sapiens transcription factor 4 (TCF4), transcript variant 17, mRNA. (from RefSeq NM_001348211)
TCF4 (ENST00000457482.7) at chr18:55227683-55322222 - Homo sapiens transcription factor 4 (TCF4), transcript variant 10, mRNA. (from RefSeq NM_001243234)
TCF4 (ENST00000568673.5) at chr18:55227679-55585908 - Homo sapiens transcription factor 4 (TCF4), transcript variant 41, mRNA. (from RefSeq NM_001369581)
TCF4 (ENST00000629387.2) at chr18:55226793-55589807 - Homo sapiens transcription factor 4 (TCF4), transcript variant 27, mRNA. (from RefSeq NM_001369567)
TCF4 (ENST00000537578.5) at chr18:55227752-55589836 - Homo sapiens transcription factor 4 (TCF4), transcript variant 46, mRNA. (from RefSeq NM_001369586)
TCF4 (ENST00000540999.5) at chr18:55227690-55586105 - Homo sapiens transcription factor 4 (TCF4), transcript variant 43, mRNA. (from RefSeq NM_001369583)
TCF4 (ENST00000354452.8) at chr18:55222185-55588192 - Homo sapiens transcription factor 4 (TCF4), transcript variant 28, mRNA. (from RefSeq NM_001369568)
SHANK1 (ENST00000293441.5) at chr19:50661827-50716938 - Homo sapiens SH3 and multiple ankyrin repeat domains 1 (SHANK1), mRNA. (from RefSeq NM_016148)
OPRM1 (ENST00000519083.5) at chr6:154039495-154109018 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1Y, non-coding RNA. (from RefSeq NR_104351)
OPRM1 (ENST00000522739.5) at chr6:154039475-154118807 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1Y3, non-coding RNA. (from RefSeq NR_104348)
OPRM1 (ENST00000522555.5) at chr6:154086507-154118969 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1K2, mRNA. (from RefSeq NM_001285526)
OPRM1 (ENST00000524163.5) at chr6:154039495-154107652 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1B4, mRNA. (from RefSeq NM_001145285)
OPRM1 (ENST00000518759.5) at chr6:154010501-154118809 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1G2, mRNA. (from RefSeq NM_001145281)
OPRM1 (ENST00000435918.6) at chr6:154039495-154109018 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1B2, mRNA. (from RefSeq NM_001145283)
OPRM1 (ENST00000419506.6) at chr6:154039495-154107652 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1B5, mRNA. (from RefSeq NM_001145286)
OPRM1 (ENST00000337049.8) at chr6:154039495-154246867 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1O, mRNA. (from RefSeq NM_001008503)
OPRM1 (ENST00000229768.9) at chr6:154039495-154093520 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1X, mRNA. (from RefSeq NM_001008505)
OPRM1 (ENST00000522236.1) at chr6:154086507-154118969 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1K1, mRNA. (from RefSeq NM_001145287)
OPRM1 (ENST00000520708.5) at chr6:154010501-154118809 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1W, mRNA. (from RefSeq NM_001285527)
OPRM1 (ENST00000452687.6) at chr6:154039456-154110453 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1Y2, non-coding RNA. (from RefSeq NR_104349)
OPRM1 (ENST00000434900.6) at chr6:154010501-154118754 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1CA, mRNA. (from RefSeq NM_001285524)
OPRM1 (ENST00000428397.6) at chr6:154039349-154091593 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1A, mRNA. (from RefSeq NM_001008504)
OPRM1 (ENST00000414028.6) at chr6:154039495-154109018 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1B3, mRNA. (from RefSeq NM_001145284)
OPRM1 (ENST00000330432.12) at chr6:154039240-154132356 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1S, mRNA. (from RefSeq NM_001285522)
OPRM1 (ENST00000524150.2) at chr6:154039479-154246860 - Receptor for endogenous opioids such as beta-endorphin  and endomorphin. Receptor for natural and synthetic opioids  including morphine, heroin, DAMGO, fentanyl, etorphine,  buprenorphin and methadone. Agonist binding to the receptor  induces coupling to an inactive GDP-bound heterotrimeric G-protein  complex and subsequent exchange of GDP for GTP in the G-protein  alpha subunit leading to dissociation of the G-protein complex  with the free GTP-bound G-protein alpha and the G-protein beta-  gamma dimer activating downstream cellular effectors. The agonist-  and cell type-specific activity is predominantly coupled to  pertussis toxin-sensitive G(i) and G(o) G alpha proteins, GNAI1,  GNAI2, GNAI3 and GNAO1 isoforms Alpha-1 and Alpha-2, and to a  lesser extend to pertussis toxin-insensitive G alpha proteins GNAZ  and GNA15. They mediate an array of downstream cellular responses,  including inhibition of adenylate cyclase activity and both N-type  and L-type calcium channels, activation of inward rectifying  potassium channels, mitogen-activated protein kinase (MAPK),  phospholipase C (PLC), phosphoinositide/protein kinase (PKC),  phosphoinositide 3-kinase (PI3K) and regulation of NF-kappa-B.  Also couples to adenylate cyclase stimulatory G alpha proteins.  The selective temporal coupling to G-proteins and subsequent  signaling can be regulated by RGSZ proteins, such as RGS9, RGS17  and RGS4. Phosphorylation by members of the GPRK subfamily of  Ser/Thr protein kinases and association with beta-arrestins is  involved in short-term receptor desensitization. Beta-arrestins  associate with the GPRK-phosphorylated receptor and uncouple it  from the G-protein thus terminating signal transduction. The  phosphorylated receptor is internalized through endocytosis via  clathrin-coated pits which involves beta-arrestins. The activation  of the ERK pathway occurs either in a G-protein-dependent or a  beta-arrestin-dependent manner and is regulated by agonist-  specific receptor phosphorylation. Acts as a class A G-protein  coupled receptor (GPCR) which dissociates from beta-arrestin at or  near the plasma membrane and undergoes rapid recycling. Receptor  down-regulation pathways are varying with the agonist and occur  dependent or independent of G-protein coupling. Endogenous ligands  induce rapid desensitization, endocytosis and recycling whereas  morphine induces only low desensitization and endocytosis.  Heterooligomerization with other GPCRs can modulate agonist  binding, signaling and trafficking properties. Involved in  neurogenesis. Isoform 12 couples to GNAS and is proposed to be  involved in excitatory effects. Isoform 16 and isoform 17 do not  bind agonists but may act through oligomerization with binding-  competent OPRM1 isoforms and reduce their ligand binding activity. (from UniProt P35372)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_001050.3 at chr17:73165010-73176633

NCBI RefSeq and Ensembl transcripts from the MANE Project (v0.6)

SSTR2 at chr17:73165010-73176633

RefSeq Genes

SSTR2 at chr17:73165010-73176633 - (NM_001050) somatostatin receptor type 2

Non-Human RefSeq Genes

SSTR2 at chr17:73165015-73170567 - (NM_001246599) somatostatin receptor type 2
SSTR2 at chr17:73169311-73170680 - (NM_001309046) somatostatin receptor type 2
Sstr2 at chr17:73169311-73170314 - (NM_009217) somatostatin receptor type 2 isoform B
Sstr2 at chr17:73169305-73170430 - (NM_019348) somatostatin receptor type 2
SSTR2 at chr17:73169320-73170429 - (NM_001031817) somatostatin receptor type 2
SSTR2 at chr17:73169320-73170429 - (NM_001011694) somatostatin receptor type 2
SSTR2 at chr17:73169340-73170429 - (NM_174467) somatostatin receptor type 2
Sstr2 at chr17:73169311-73170511 - (NM_001042606) somatostatin receptor type 2 isoform A
SSTR2 at chr17:73169414-73170444 - (NM_001030345) somatostatin receptor type 2
sstr2.L at chr17:73169428-73170429 - (NM_001092075) somatostatin receptor 2 L homeolog

Basic Gene Annotation Set from GENCODE Version 33 (Ensembl 99)

SSTR2 at chr17:73165010-73176633

Comprehensive Gene Annotation Set from GENCODE Version 33 (Ensembl 99)

SSTR2 at chr17:73165010-73176633
SSTR2 at chr17:73165012-73169311

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

SSTR2 at chr17:73165010-73176633

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

SSTR2 at chr17:73165010-73176633
SSTR2 at chr17:73165012-73169311

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

SSTR2 at chr17:73165012-73176633

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73176633

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

SSTR2 at chr17:73165012-73176633

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73176633

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

SSTR2 at chr17:73165012-73176633

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73176633

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

SSTR2 at chr17:73165012-73176633

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73176633

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

SSTR2 at chr17:73165012-73176633

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73176633

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

SSTR2 at chr17:73165012-73176633

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73176633

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

SSTR2 at chr17:73165012-73176633

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73176633

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

SSTR2 at chr17:73165012-73176633

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73176633

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

SSTR2 at chr17:73165012-73171046

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

SSTR2 at chr17:73165012-73169311
SSTR2 at chr17:73165012-73171046

International Knockout Mouse Consortium Genes Mapped to Human Genome

Sstr2_102569 at chr17:73165021-73171955
Sstr2_44307 at chr17:73165021-73171955
Sstr2_92556 at chr17:73165021-73171955

Alias of STS Marker

SSTR2 at chr17:73069620-73270023 - (SSTR2)

Human Aligned mRNA Search Results

BC019610 - Homo sapiens somatostatin receptor 2, mRNA (cDNA clone MGC:24950 IMAGE:3875163), complete cds.
BC095495 - Homo sapiens somatostatin receptor 2, mRNA (cDNA clone MGC:111698 IMAGE:6971895), complete cds.
AK313866 - Homo sapiens cDNA, FLJ94499, highly similar to Homo sapiens somatostatin receptor 2 (SSTR2), mRNA.

Non-Human Aligned mRNA Search Results

X68951 - M.musculus mRNA for somatostatin receptor.
KT261513 - Gasterosteus aculeatus somatostatin receptor 2b (SSTR2b) mRNA, partial cds.
KT261512 - Gasterosteus aculeatus somatostatin receptor 2a (SSTR2a) mRNA, partial cds.
BC140348 - Synthetic construct Mus musculus clone IMAGE:100014382, MGC:173389 somatostatin receptor 2 (Sstr2) mRNA, encodes complete protein.
BC146535 - Synthetic construct Mus musculus clone IMAGE:100014956, MGC:180320 somatostatin receptor 2 (Sstr2) mRNA, encodes complete protein.
FJ418171 - Cavia porcellus somatostatin receptor 2 (sstr2) mRNA, partial cds.
MK153163 - Epinephelus akaara somatostatin receptor type 2 (sstr2) mRNA, complete cds.
AY305401 - Canis familiaris somatostatin receptor 2 (SSTR2) mRNA, partial cds.
LC020103 - Felis catus SSTR2 mRNA for somatostatin receptor type 2, complete cds.
AY888419 - Synthetic construct Homo sapiens clone FLH020477.01X somatostatin receptor 2 (SSTR2) mRNA, complete cds.
AY888420 - Synthetic construct Homo sapiens clone FLH020478.01X somatostatin receptor 2 (SSTR2) mRNA, complete cds.
AY891051 - Synthetic construct Homo sapiens clone FLH020473.01L somatostatin receptor 2 (SSTR2) mRNA, partial cds.
AY893098 - Synthetic construct Homo sapiens clone FLH135323.01L somatostatin receptor 2 (SSTR2) mRNA, partial cds.
AY894021 - Synthetic construct Homo sapiens clone FLH131050.01L somatostatin receptor 2 (SSTR2) mRNA, partial cds.
JU336077 - TSA: Macaca mulatta Mamu_524264 mRNA sequence.
EU571473 - Ctenopharyngodon idella somatostatin receptor 2 (SSTR2) mRNA, complete cds.