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Gencode Genes

SMAD2 (ENST00000262160.11) at chr18:47808957-47930659 - Homo sapiens SMAD family member 2 (SMAD2), transcript variant 1, mRNA. (from RefSeq NM_005901)
SMAD2 (ENST00000591214.5) at chr18:47844912-47930842 - SMAD family member 2 (from HGNC SMAD2)
SMAD2 (ENST00000589877.5) at chr18:47870473-47930855 - SMAD family member 2 (from HGNC SMAD2)
SMAD2 (ENST00000587421.5) at chr18:47869352-47930362 - SMAD family member 2 (from HGNC SMAD2)
SMAD2 (ENST00000587353.5) at chr18:47868263-47886923 - SMAD family member 2 (from HGNC SMAD2)
SMAD2 (ENST00000587269.5) at chr18:47868326-47930599 - SMAD family member 2 (from HGNC SMAD2)
SMAD2 (ENST00000586514.5) at chr18:47868327-47930837 - SMAD family member 2 (from HGNC SMAD2)
SMAD2 (ENST00000586487.2) at chr18:47869422-47895725 - SMAD family member 2 (from HGNC SMAD2)
SMAD2 (ENST00000586040.5) at chr18:47841225-47896811 - Receptor-regulated SMAD (R-SMAD) that is an  intracellular signal transducer and transcriptional modulator  activated by TGF-beta (transforming growth factor) and activin  type 1 receptor kinases. Binds the TRE element in the promoter  region of many genes that are regulated by TGF-beta and, on  formation of the SMAD2/SMAD4 complex, activates transcription. May  act as a tumor suppressor in colorectal carcinoma. Positively  regulates PDPK1 kinase activity by stimulating its dissociation  from the 14-3-3 protein YWHAQ which acts as a negative regulator. (from UniProt Q15796)
SMAD2 (ENST00000585978.1) at chr18:47870475-47923642 - SMAD family member 2 (from HGNC SMAD2)
SMAD2 (ENST00000402690.6) at chr18:47831551-47931141 - Homo sapiens SMAD family member 2 (SMAD2), transcript variant 2, mRNA. (from RefSeq NM_001003652)
SMAD2 (ENST00000356825.8) at chr18:47833096-47931146 - Homo sapiens SMAD family member 2 (SMAD2), transcript variant 3, mRNA. (from RefSeq NM_001135937)
ZFYVE9 (ENST00000371591.1) at chr1:52216380-52346686 - Early endosomal protein that functions to recruit  SMAD2/SMAD3 to intracellular membranes and to the TGF-beta  receptor. Plays a significant role in TGF-mediated signaling by  regulating the subcellular location of SMAD2 and SMAD3 and  modulating the transcriptional activity of the SMAD3/SMAD4  complex. Possibly associated with TGF-beta receptor  internalization. (from UniProt O95405)
SMAD4 (ENST00000398417.6) at chr18:51029614-51085045 - Common SMAD (co-SMAD) is the coactivator and mediator of  signal transduction by TGF-beta (transforming growth factor).  Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that  forms in the nucleus and is required for the TGF-mediated  signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to  DNA and provides an activation function required for SMAD1 or  SMAD2 to stimulate transcription. Component of the multimeric  SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site;  required for syngernistic transcriptional activity in response to  TGF-beta. May act as a tumor suppressor. Positively regulates  PDPK1 kinase activity by stimulating its dissociation from the 14-  3-3 protein YWHAQ which acts as a negative regulator. (from UniProt Q13485)
NEDD4L (ENST00000256830.13) at chr18:58044661-58396573 - E3 ubiquitin-protein ligase which accepts ubiquitin from  an E2 ubiquitin-conjugating enzyme in the form of a thioester and  then directly transfers the ubiquitin to targeted substrates.  Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1  ubiquitination and proteasome-dependent degradation. Promotes  ubiquitination and internalization of various plasma membrane  channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8,  Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of  SGK1 and TNK2. (from UniProt Q96PU5)
FOXH1 (ENST00000377317.5) at chr8:144473412-144475849 - Homo sapiens forkhead box H1 (FOXH1), mRNA. (from RefSeq NM_003923)
TGIF1 (ENST00000472042.1) at chr18:3455414-3458411 - Binds to a retinoid X receptor (RXR) responsive element  from the cellular retinol-binding protein II promoter (CRBPII-  RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha  transcription activation of the retinoic acid responsive element.  Active transcriptional corepressor of SMAD2. Links the nodal  signaling pathway to the bifurcation of the forebrain and the  establishment of ventral midline structures. May participate in  the transmission of nuclear signals during development and in the  adult, as illustrated by the down-modulation of the RXR alpha  activities. (from UniProt Q15583)
TGIF1 (ENST00000407501.6) at chr18:3449882-3458349 - Binds to a retinoid X receptor (RXR) responsive element  from the cellular retinol-binding protein II promoter (CRBPII-  RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha  transcription activation of the retinoic acid responsive element.  Active transcriptional corepressor of SMAD2. Links the nodal  signaling pathway to the bifurcation of the forebrain and the  establishment of ventral midline structures. May participate in  the transmission of nuclear signals during development and in the  adult, as illustrated by the down-modulation of the RXR alpha  activities. (from UniProt Q15583)
TGIF1 (ENST00000345133.9) at chr18:3451670-3458123 - Binds to a retinoid X receptor (RXR) responsive element  from the cellular retinol-binding protein II promoter (CRBPII-  RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha  transcription activation of the retinoic acid responsive element.  Active transcriptional corepressor of SMAD2. Links the nodal  signaling pathway to the bifurcation of the forebrain and the  establishment of ventral midline structures. May participate in  the transmission of nuclear signals during development and in the  adult, as illustrated by the down-modulation of the RXR alpha  activities. (from UniProt Q15583)
SKOR2 (ENST00000400404.1) at chr18:47231123-47249183 - Homo sapiens SKI family transcriptional corepressor 2 (SKOR2), transcript variant 2, mRNA. (from RefSeq NM_001037802)
SKOR1 (ENST00000380035.3) at chr15:67825509-67834582 - Homo sapiens SKI family transcriptional corepressor 1 (SKOR1), mRNA. (from RefSeq NM_001365915)
SKOR1 (ENST00000341418.10) at chr15:67819704-67833836 - Acts as a transcriptional corepressor of LBX1 (By  similarity). Inhibits BMP signaling. (from UniProt P84550)
TGFBRAP1 (ENST00000595531.5) at chr2:105264391-105308321 - Plays a role in the TGF-beta/activin signaling pathway.  It associates with inactive heteromeric TGF-beta and activin  receptor complexes, mainly through the type II receptor, and is  released upon activation of signaling. May recruit SMAD4 to the  vicinity of the receptor complex and facilitate its interaction  with receptor-regulated Smads, such as SMAD2. (from UniProt Q8WUH2)
TGFBRAP1 (ENST00000258449.2) at chr2:105267121-105308321 - Plays a role in the TGF-beta/activin signaling pathway.  It associates with inactive heteromeric TGF-beta and activin  receptor complexes, mainly through the type II receptor, and is  released upon activation of signaling. May recruit SMAD4 to the  vicinity of the receptor complex and facilitate its interaction  with receptor-regulated Smads, such as SMAD2. (from UniProt Q8WUH2)
ZEB2 (ENST00000558170.6) at chr2:144389285-144517551 - Transcriptional inhibitor that binds to DNA sequence 5'-  CACCT-3' in different promoters. Represses transcription of E-  cadherin. (from UniProt O60315)
ZEB2 (ENST00000409487.7) at chr2:144388018-144517825 - Transcriptional inhibitor that binds to DNA sequence 5'-  CACCT-3' in different promoters. Represses transcription of E-  cadherin. (from UniProt O60315)
ZFYVE9 (ENST00000287727.7) at chr1:52142094-52346685 - Homo sapiens zinc finger FYVE-type containing 9 (ZFYVE9), transcript variant 3, mRNA. (from RefSeq NM_004799)
ZFYVE9 (ENST00000357206.6) at chr1:52142374-52346515 - Homo sapiens zinc finger FYVE-type containing 9 (ZFYVE9), transcript variant 1, mRNA. (from RefSeq NM_007324)
DOCK9 (ENST00000376460.5) at chr13:98793487-98977990 - Homo sapiens dedicator of cytokinesis 9 (DOCK9), transcript variant 8, mRNA. (from RefSeq NM_001366678)
DOCK9 (ENST00000652315.1) at chr13:98793490-99086406 - Homo sapiens dedicator of cytokinesis 9 (DOCK9), transcript variant 1, mRNA. (from RefSeq NM_015296)
DOCK9 (ENST00000627024.2) at chr13:98860181-98978084 - Homo sapiens dedicator of cytokinesis 9 (DOCK9), transcript variant 4, mRNA. (from RefSeq NM_001130050)
ELAC2 (ENST00000426905.7) at chr17:12992560-13017999 - Homo sapiens elaC ribonuclease Z 2 (ELAC2), transcript variant 3, mRNA. (from RefSeq NM_001165962)
ELAC2 (ENST00000338034.9) at chr17:12991612-13018027 - Homo sapiens elaC ribonuclease Z 2 (ELAC2), transcript variant 2, mRNA. (from RefSeq NM_173717)
FHL3 (ENST00000373016.4) at chr1:37996770-38005514 - Homo sapiens four and a half LIM domains 3 (FHL3), transcript variant 1, mRNA. (from RefSeq NM_004468)
WWP1 (ENST00000265428.4) at chr8:86374041-86467476 - E3 ubiquitin-protein ligase which accepts ubiquitin from  an E2 ubiquitin-conjugating enzyme in the form of a thioester and  then directly transfers the ubiquitin to targeted substrates.  Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5  and TP63 and promotes their proteasomal degradation. Ubiquitinates  RNF11 without targeting it for degradation. Ubiquitinates and  promotes degradation of TGFBR1; the ubiquitination is enhanced by  SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes  degradation of SMAD2 in response to TGF-beta signaling, which  requires interaction with TGIF. (from UniProt Q9H0M0)
USP9Y (ENST00000651177.1) at chrY:12662368-12860802 - May function as a ubiquitin-protein or polyubiquitin  hydrolase involved both in the processing of ubiquitin precursors  and of ubiquitinated proteins. May therefore play an important  role regulatory role at the level of protein turnover by  preventing degradation of proteins through the removal of  conjugated ubiquitin. Essential component of TGF-beta/BMP  signaling cascade. Deubiquitinates monoubiquitinated SMAD4,  opposing the activity of E3 ubiquitin-protein ligase TRIM33.  Monoubiquitination of SMAD4 hampers its ability to form a stable  complex with activated SMAD2/3 resulting in inhibition of TGF-  beta/BMP signaling cascade. Deubiqitination of SMAD4 by USP9X re-  empowers its competence to mediate TGF-beta signaling (By  similarity). (from UniProt O00507)
SMURF2 (ENST00000262435.14) at chr17:64542282-64662307 - Homo sapiens SMAD specific E3 ubiquitin protein ligase 2 (SMURF2), mRNA. (from RefSeq NM_022739)
EID2 (ENST00000390658.4) at chr19:39538707-39540161 - Homo sapiens EP300 interacting inhibitor of differentiation 2 (EID2), mRNA. (from RefSeq NM_153232)
TGIF1 (ENST00000548489.6) at chr18:3412856-3458406 - Homo sapiens TGFB induced factor homeobox 1 (TGIF1), transcript variant 11, mRNA. (from RefSeq NM_001278686)
TGIF1 (ENST00000400167.6) at chr18:3453774-3458406 - Homo sapiens TGFB induced factor homeobox 1 (TGIF1), transcript variant 7, mRNA. (from RefSeq NM_173211)
LEMD3 (ENST00000308330.3) at chr12:65169583-65248355 - Homo sapiens LEM domain containing 3 (LEMD3), transcript variant 1, mRNA. (from RefSeq NM_014319)
TGIF1 (ENST00000343820.9) at chr18:3449704-3458411 - Homo sapiens TGFB induced factor homeobox 1 (TGIF1), transcript variant 3, mRNA. (from RefSeq NM_173208)
TGIF1 (ENST00000618001.4) at chr18:3447609-3459978 - Homo sapiens TGFB induced factor homeobox 1 (TGIF1), transcript variant 2, mRNA. (from RefSeq NM_173207)
TGIF1 (ENST00000551541.5) at chr18:3451593-3457944 - Homo sapiens TGFB induced factor homeobox 1 (TGIF1), transcript variant 6, mRNA. (from RefSeq NM_173210)
TGIF1 (ENST00000405385.7) at chr18:3449651-3458406 - Homo sapiens TGFB induced factor homeobox 1 (TGIF1), transcript variant 5, mRNA. (from RefSeq NM_173209)
TGIF1 (ENST00000401449.5) at chr18:3411927-3458406 - Homo sapiens TGFB induced factor homeobox 1 (TGIF1), transcript variant 8, mRNA. (from RefSeq NM_174886)
TGIF1 (ENST00000330513.9) at chr18:3451677-3458411 - Homo sapiens TGFB induced factor homeobox 1 (TGIF1), transcript variant 1, mRNA. (from RefSeq NM_170695)
VPS39 (ENST00000318006.9) at chr15:42158701-42208316 - Homo sapiens VPS39 subunit of HOPS complex (VPS39), transcript variant 2, mRNA. (from RefSeq NM_015289)
VPS39 (ENST00000348544.4) at chr15:42160754-42208153 - Homo sapiens VPS39 subunit of HOPS complex (VPS39), transcript variant 1, mRNA. (from RefSeq NM_001301138)
ZEB2 (ENST00000539609.7) at chr2:144389213-144520119 - Homo sapiens zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 2, mRNA. (from RefSeq NM_001171653)
ZEB2 (ENST00000627532.3) at chr2:144384081-144520119 - Homo sapiens zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 1, mRNA. (from RefSeq NM_014795)
NEFM (ENST00000433454.3) at chr8:24914942-24919098 - Homo sapiens neurofilament medium (NEFM), transcript variant 2, mRNA. (from RefSeq NM_001105541)
NEFM (ENST00000221166.10) at chr8:24913761-24919093 - Homo sapiens neurofilament medium (NEFM), transcript variant 1, mRNA. (from RefSeq NM_005382)
SKIL (ENST00000426052.6) at chr3:170357734-170392947 - Homo sapiens SKI like proto-oncogene (SKIL), transcript variant 3, mRNA. (from RefSeq NM_001145098)
SKIL (ENST00000458537.7) at chr3:170359623-170396835 - Homo sapiens SKI like proto-oncogene (SKIL), transcript variant 4, mRNA. (from RefSeq NM_001248008)
SKIL (ENST00000413427.6) at chr3:170359623-170392493 - Homo sapiens SKI like proto-oncogene (SKIL), transcript variant 2, mRNA. (from RefSeq NM_001145097)
SKIL (ENST00000259119.9) at chr3:170357715-170396835 - Homo sapiens SKI like proto-oncogene (SKIL), transcript variant 1, mRNA. (from RefSeq NM_005414)
RBPMS (ENST00000320203.8) at chr8:30384511-30572256 - Homo sapiens RNA binding protein, mRNA processing factor (RBPMS), transcript variant 4, mRNA. (from RefSeq NM_006867)
RBPMS (ENST00000287771.9) at chr8:30384527-30572256 - Homo sapiens RNA binding protein, mRNA processing factor (RBPMS), transcript variant 2, mRNA. (from RefSeq NM_001008711)
ACVR1C (ENST00000409680.7) at chr2:157533742-157597560 - Homo sapiens activin A receptor type 1C (ACVR1C), transcript variant 2, mRNA. (from RefSeq NM_001111031)
ACVR1C (ENST00000348328.9) at chr2:157533742-157628727 - Homo sapiens activin A receptor type 1C (ACVR1C), transcript variant 4, mRNA. (from RefSeq NM_001111033)
RBPMS (ENST00000397323.9) at chr8:30384541-30572256 - Homo sapiens RNA binding protein, mRNA processing factor (RBPMS), transcript variant 1, mRNA. (from RefSeq NM_001008710)
ACVR1C (ENST00000335450.7) at chr2:157533742-157628727 - Homo sapiens activin A receptor type 1C (ACVR1C), transcript variant 3, mRNA. (from RefSeq NM_001111032)
RBPMS (ENST00000339877.8) at chr8:30384511-30547522 - Homo sapiens RNA binding protein, mRNA processing factor (RBPMS), transcript variant 3, mRNA. (from RefSeq NM_001008712)
ACVR1C (ENST00000243349.13) at chr2:157526767-157628864 - Homo sapiens activin A receptor type 1C (ACVR1C), transcript variant 1, mRNA. (from RefSeq NM_145259)
CHGB (ENST00000378961.9) at chr20:5911510-5925353 - Homo sapiens chromogranin B (CHGB), mRNA. (from RefSeq NM_001819)
ADAMTSL2 (ENST00000393060.1) at chr9:133534853-133575518 - Interacts with LTBP1. (from UniProt Q86TH1)
SMAD7 (ENST00000589634.1) at chr18:48921372-48950424 - Homo sapiens SMAD family member 7 (SMAD7), transcript variant 2, mRNA. (from RefSeq NM_001190821)
SMAD7 (ENST00000591805.5) at chr18:48920993-48949333 - Homo sapiens SMAD family member 7 (SMAD7), transcript variant 3, mRNA. (from RefSeq NM_001190822)
SMAD7 (ENST00000262158.7) at chr18:48919853-48952052 - Homo sapiens SMAD family member 7 (SMAD7), transcript variant 1, mRNA. (from RefSeq NM_005904)
TGFBRAP1 (ENST00000393359.7) at chr2:105264414-105329735 - Homo sapiens transforming growth factor beta receptor associated protein 1 (TGFBRAP1), transcript variant 4, non-coding RNA. (from RefSeq NR_137328)
DAB2 (ENST00000509337.5) at chr5:39373021-39394400 - Adapter protein that functions as clathrin-associated  sorting protein (CLASP) required for clathrin-mediated endocytosis  of selected cargo proteins. Can bind and assemble clathrin, and  binds simultaneously to phosphatidylinositol 4,5-bisphosphate  (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY  internalization motifs, such as the LDL receptor, to recruit them  to clathrin-coated pits. Can function in clathrin-mediated  endocytosis independently of the AP-2 complex. Involved in  endocytosis of integrin beta-1; this function seems to redundant  with the AP-2 complex and seems to require DAB2 binding to  endocytosis accessory EH domain-containing proteins such as EPS15,  EPS15L1 and ITSN1. Involved in endocytosis of cystic fibrosis  transmembrane conductance regulator/CFTR. Involved in endocytosis  of megalin/LRP2 lipoprotein receptor during embryonal development.  Required for recycling of the TGF-beta receptor. Involved in CFTR  trafficking to the late endosome. Involved in several receptor-  mediated signaling pathways. Involved in TGF-beta receptor  signaling and facilitates phosphorylation of the signal transducer  SMAD2. Mediates TFG-beta-stimulated JNK activation. May inhibit  the canoniocal Wnt/beta-catenin signaling pathway by stabilizing  the beta-catenin destruction complex through a competing  association with axin preventing its dephosphorylation through  protein phosphatase 1 (PP1). Sequesters LRP6 towards clathrin-  mediated endocytosis, leading to inhibition of Wnt/beta-catenin  signaling. May activate non-canonical Wnt signaling. In cell  surface growth factor/Ras signaling pathways proposed to inhibit  ERK activation by interrupting the binding of GRB2 to SOS1 and to  inhibit SRC by preventing its activating phosphorylation at 'Tyr-  419'. Proposed to be involved in modulation of androgen receptor  (AR) signaling mediated by SRC activation; seems to compete with  AR for interaction with SRC. Plays a role in the CSF-1 signal  transduction pathway. Plays a role in cellular differentiation.  Involved in cell positioning and formation of visceral endoderm  (VE) during embryogenesis and proposed to be required in the VE to  respond to Nodal signaling coming from the epiblast. Required for  the epithelial to mesenchymal transition, a process necessary for  proper embryonic development. May be involved in myeloid cell  differentiation and can induce macrophage adhesion and spreading.  May act as a tumor suppressor. (from UniProt P98082)
DAB2 (ENST00000339788.10) at chr5:39371678-39424980 - Adapter protein that functions as clathrin-associated  sorting protein (CLASP) required for clathrin-mediated endocytosis  of selected cargo proteins. Can bind and assemble clathrin, and  binds simultaneously to phosphatidylinositol 4,5-bisphosphate  (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY  internalization motifs, such as the LDL receptor, to recruit them  to clathrin-coated pits. Can function in clathrin-mediated  endocytosis independently of the AP-2 complex. Involved in  endocytosis of integrin beta-1; this function seems to redundant  with the AP-2 complex and seems to require DAB2 binding to  endocytosis accessory EH domain-containing proteins such as EPS15,  EPS15L1 and ITSN1. Involved in endocytosis of cystic fibrosis  transmembrane conductance regulator/CFTR. Involved in endocytosis  of megalin/LRP2 lipoprotein receptor during embryonal development.  Required for recycling of the TGF-beta receptor. Involved in CFTR  trafficking to the late endosome. Involved in several receptor-  mediated signaling pathways. Involved in TGF-beta receptor  signaling and facilitates phosphorylation of the signal transducer  SMAD2. Mediates TFG-beta-stimulated JNK activation. May inhibit  the canoniocal Wnt/beta-catenin signaling pathway by stabilizing  the beta-catenin destruction complex through a competing  association with axin preventing its dephosphorylation through  protein phosphatase 1 (PP1). Sequesters LRP6 towards clathrin-  mediated endocytosis, leading to inhibition of Wnt/beta-catenin  signaling. May activate non-canonical Wnt signaling. In cell  surface growth factor/Ras signaling pathways proposed to inhibit  ERK activation by interrupting the binding of GRB2 to SOS1 and to  inhibit SRC by preventing its activating phosphorylation at 'Tyr-  419'. Proposed to be involved in modulation of androgen receptor  (AR) signaling mediated by SRC activation; seems to compete with  AR for interaction with SRC. Plays a role in the CSF-1 signal  transduction pathway. Plays a role in cellular differentiation.  Involved in cell positioning and formation of visceral endoderm  (VE) during embryogenesis and proposed to be required in the VE to  respond to Nodal signaling coming from the epiblast. Required for  the epithelial to mesenchymal transition, a process necessary for  proper embryonic development. May be involved in myeloid cell  differentiation and can induce macrophage adhesion and spreading.  May act as a tumor suppressor. (from UniProt P98082)
RANBP3 (ENST00000340578.10) at chr19:5916139-5978140 - Homo sapiens RAN binding protein 3 (RANBP3), transcript variant RANBP3-d, mRNA. (from RefSeq NM_007322)
RANBP3 (ENST00000439268.6) at chr19:5916139-5978108 - Homo sapiens RAN binding protein 3 (RANBP3), transcript variant RANBP3-a, mRNA. (from RefSeq NM_003624)
RANBP3 (ENST00000034275.12) at chr19:5917352-5978086 - Homo sapiens RAN binding protein 3 (RANBP3), transcript variant RANBP3-b, mRNA. (from RefSeq NM_007320)
ACVR1B (ENST00000426655.6) at chr12:51951702-51992341 - Transmembrane serine/threonine kinase activin type-1  receptor forming an activin receptor complex with activin receptor  type-2 (ACVR2A or ACVR2B). Transduces the activin signal from the  cell surface to the cytoplasm and is thus regulating a many  physiological and pathological processes including neuronal  differentiation and neuronal survival, hair follicle development  and cycling, FSH production by the pituitary gland, wound healing,  extracellular matrix production, immunosuppression and  carcinogenesis. Activin is also thought to have a paracrine or  autocrine role in follicular development in the ovary. Within the  receptor complex, type-2 receptors (ACVR2A and/or ACVR2B) act as a  primary activin receptors whereas the type-1 receptors like ACVR1B  act as downstream transducers of activin signals. Activin binds to  type-2 receptor at the plasma membrane and activates its serine-  threonine kinase. The activated receptor type-2 then  phosphorylates and activates the type-1 receptor such as ACVR1B.  Once activated, the type-1 receptor binds and phosphorylates the  SMAD proteins SMAD2 and SMAD3, on serine residues of the C-  terminal tail. Soon after their association with the activin  receptor and subsequent phosphorylation, SMAD2 and SMAD3 are  released into the cytoplasm where they interact with the common  partner SMAD4. This SMAD complex translocates into the nucleus  where it mediates activin-induced transcription. Inhibitory SMAD7,  which is recruited to ACVR1B through FKBP1A, can prevent the  association of SMAD2 and SMAD3 with the activin receptor complex,  thereby blocking the activin signal. Activin signal transduction  is also antagonized by the binding to the receptor of inhibin-B  via the IGSF1 inhibin coreceptor. ACVR1B also phosphorylates TDP2. (from UniProt P36896)
ACVR1B (ENST00000415850.6) at chr12:51951744-51987346 - Transmembrane serine/threonine kinase activin type-1  receptor forming an activin receptor complex with activin receptor  type-2 (ACVR2A or ACVR2B). Transduces the activin signal from the  cell surface to the cytoplasm and is thus regulating a many  physiological and pathological processes including neuronal  differentiation and neuronal survival, hair follicle development  and cycling, FSH production by the pituitary gland, wound healing,  extracellular matrix production, immunosuppression and  carcinogenesis. Activin is also thought to have a paracrine or  autocrine role in follicular development in the ovary. Within the  receptor complex, type-2 receptors (ACVR2A and/or ACVR2B) act as a  primary activin receptors whereas the type-1 receptors like ACVR1B  act as downstream transducers of activin signals. Activin binds to  type-2 receptor at the plasma membrane and activates its serine-  threonine kinase. The activated receptor type-2 then  phosphorylates and activates the type-1 receptor such as ACVR1B.  Once activated, the type-1 receptor binds and phosphorylates the  SMAD proteins SMAD2 and SMAD3, on serine residues of the C-  terminal tail. Soon after their association with the activin  receptor and subsequent phosphorylation, SMAD2 and SMAD3 are  released into the cytoplasm where they interact with the common  partner SMAD4. This SMAD complex translocates into the nucleus  where it mediates activin-induced transcription. Inhibitory SMAD7,  which is recruited to ACVR1B through FKBP1A, can prevent the  association of SMAD2 and SMAD3 with the activin receptor complex,  thereby blocking the activin signal. Activin signal transduction  is also antagonized by the binding to the receptor of inhibin-B  via the IGSF1 inhibin coreceptor. ACVR1B also phosphorylates TDP2. (from UniProt P36896)
NEDD4L (ENST00000456986.5) at chr18:58047226-58401540 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant f, mRNA. (from RefSeq NM_001144965)
PDPK1 (ENST00000441549.7) at chr16:2537997-2597920 - Homo sapiens 3-phosphoinositide dependent protein kinase 1 (PDPK1), transcript variant 3, mRNA. (from RefSeq NM_001261816)
PDPK1 (ENST00000268673.11) at chr16:2538003-2601095 - Homo sapiens 3-phosphoinositide dependent protein kinase 1 (PDPK1), transcript variant 2, mRNA. (from RefSeq NM_031268)
PDPK1 (ENST00000342085.9) at chr16:2538021-2603188 - Homo sapiens 3-phosphoinositide dependent protein kinase 1 (PDPK1), transcript variant 1, mRNA. (from RefSeq NM_002613)
PPM1A (ENST00000325658.3) at chr14:60249441-60288555 - Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A), transcript variant 2, mRNA. (from RefSeq NM_177951)
PPM1A (ENST00000325642.7) at chr14:60245752-60292731 - Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A), transcript variant 3, mRNA. (from RefSeq NM_177952)
NEDD4L (ENST00000586263.5) at chr18:58149337-58396573 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant h, mRNA. (from RefSeq NM_001144969)
NEDD4L (ENST00000435432.6) at chr18:58149333-58396551 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant k, mRNA. (from RefSeq NM_001144971)
NEDD4L (ENST00000357895.9) at chr18:58149333-58396705 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant g, mRNA. (from RefSeq NM_001144968)
PPM1A (ENST00000395076.9) at chr14:60249221-60299087 - Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A), transcript variant 1, mRNA. (from RefSeq NM_021003)
NEDD4L (ENST00000456173.6) at chr18:58195390-58398157 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant c, mRNA. (from RefSeq NM_001144970)
NEDD4L (ENST00000431212.6) at chr18:58221535-58396578 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant a, mRNA. (from RefSeq NM_001144966)
NEDD4L (ENST00000382850.8) at chr18:58044548-58401539 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant d, mRNA. (from RefSeq NM_015277)
NEDD4L (ENST00000356462.10) at chr18:58044367-58396574 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant i, mRNA. (from RefSeq NM_001243960)
NEDD4L (ENST00000400345.8) at chr18:58044226-58401539 - Homo sapiens NEDD4 like E3 ubiquitin protein ligase (NEDD4L), transcript variant j, mRNA. (from RefSeq NM_001144967)
USP15 (ENST00000312635.10) at chr12:62260397-62336690 - Homo sapiens ubiquitin specific peptidase 15 (USP15), transcript variant 3, mRNA. (from RefSeq NM_001252079)
TRIM33 (ENST00000358465.7) at chr1:114392790-114511203 - Homo sapiens tripartite motif containing 33 (TRIM33), transcript variant a, mRNA. (from RefSeq NM_015906)
TRIM33 (ENST00000369543.6) at chr1:114397608-114511160 - Homo sapiens tripartite motif containing 33 (TRIM33), transcript variant b, mRNA. (from RefSeq NM_033020)
WWTR1 (ENST00000467467.5) at chr3:149520610-149658025 - Homo sapiens WW domain containing transcription regulator 1 (WWTR1), transcript variant 3, mRNA. (from RefSeq NM_001168280)
WWTR1 (ENST00000465804.5) at chr3:149517235-149703273 - Homo sapiens WW domain containing transcription regulator 1 (WWTR1), transcript variant 4, mRNA. (from RefSeq NM_001348362)
WWTR1 (ENST00000360632.7) at chr3:149520245-149658101 - Homo sapiens WW domain containing transcription regulator 1 (WWTR1), transcript variant 1, mRNA. (from RefSeq NM_015472)
SKI (ENST00000378536.5) at chr1:2228319-2310213 - Homo sapiens SKI proto-oncogene (SKI), mRNA. (from RefSeq NM_003036)
MAGI2 (ENST00000354212.9) at chr7:78017055-79453667 - Homo sapiens membrane associated guanylate kinase, WW and PDZ domain containing 2 (MAGI2), transcript variant 1, mRNA. (from RefSeq NM_012301)
MAGI2 (ENST00000419488.5) at chr7:78017076-79453555 - Homo sapiens membrane associated guanylate kinase, WW and PDZ domain containing 2 (MAGI2), transcript variant 2, mRNA. (from RefSeq NM_001301128)
FKBP1A (ENST00000381719.7) at chr20:1371722-1393028 - Homo sapiens FKBP prolyl isomerase 1A (FKBP1A), transcript variant 2, mRNA. (from RefSeq NM_054014)
FKBP1A (ENST00000400137.9) at chr20:1368978-1393054 - Homo sapiens FKBP prolyl isomerase 1A (FKBP1A), transcript variant 1, mRNA. (from RefSeq NM_000801)
USP9Y (ENST00000338981.7) at chrY:12701231-12860839 - Homo sapiens ubiquitin specific peptidase 9 Y-linked (USP9Y), mRNA. (from RefSeq NM_004654)
ZFR (ENST00000265069.13) at chr5:32354350-32444740 - Homo sapiens zinc finger RNA binding protein (ZFR), non-coding RNA. (from RefSeq NR_144318)
TGFBR1 (ENST00000552516.5) at chr9:99105150-99153658 - Homo sapiens transforming growth factor beta receptor 1 (TGFBR1), transcript variant 3, mRNA. (from RefSeq NM_001306210)
TGFBR1 (ENST00000374990.6) at chr9:99105111-99153649 - Homo sapiens transforming growth factor beta receptor 1 (TGFBR1), transcript variant 2, mRNA. (from RefSeq NM_001130916)
USP15 (ENST00000353364.7) at chr12:62260338-62416389 - Homo sapiens ubiquitin specific peptidase 15 (USP15), transcript variant 16, non-coding RNA. (from RefSeq NR_147082)
USP15 (ENST00000280377.10) at chr12:62260404-62416389 - Homo sapiens ubiquitin specific peptidase 15 (USP15), transcript variant 13, non-coding RNA. (from RefSeq NR_147079)
TGFBR2 (ENST00000295754.9) at chr3:30606502-30694134 - Homo sapiens transforming growth factor beta receptor 2 (TGFBR2), transcript variant 2, mRNA. (from RefSeq NM_003242)
TGFBR2 (ENST00000359013.4) at chr3:30606601-30694142 - Homo sapiens transforming growth factor beta receptor 2 (TGFBR2), transcript variant 1, mRNA. (from RefSeq NM_001024847)
WWP2 (ENST00000569174.5) at chr16:69776187-69910250 - Homo sapiens WW domain containing E3 ubiquitin protein ligase 2 (WWP2), transcript variant 6, mRNA. (from RefSeq NM_001270455)
WWP2 (ENST00000356003.6) at chr16:69838737-69941741 - Homo sapiens WW domain containing E3 ubiquitin protein ligase 2 (WWP2), transcript variant 4, mRNA. (from RefSeq NM_001270453)
WWP2 (ENST00000359154.6) at chr16:69762306-69941741 - Homo sapiens WW domain containing E3 ubiquitin protein ligase 2 (WWP2), transcript variant 1, mRNA. (from RefSeq NM_007014)
CITED2 (ENST00000536159.2) at chr6:139372255-139374362 - Homo sapiens Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 (CITED2), transcript variant 2, mRNA. (from RefSeq NM_001168388)
MEN1 (ENST00000315422.9) at chr11:64803514-64810551 - Homo sapiens menin 1 (MEN1), transcript variant 6, mRNA. (from RefSeq NM_001370261)
WWP2 (ENST00000568684.1) at chr16:69924990-69941738 - Homo sapiens WW domain containing E3 ubiquitin protein ligase 2 (WWP2), transcript variant 2, mRNA. (from RefSeq NM_199424)
CITED2 (ENST00000367651.4) at chr6:139371807-139374648 - Homo sapiens Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 (CITED2), transcript variant 1, mRNA. (from RefSeq NM_006079)
MEN1 (ENST00000312049.10) at chr11:64803516-64810716 - Homo sapiens menin 1 (MEN1), transcript variant 2, mRNA. (from RefSeq NM_130799)
MEN1 (ENST00000394376.5) at chr11:64803524-64811294 - Homo sapiens menin 1 (MEN1), transcript variant e1F1, mRNA. (from RefSeq NM_130804)
MEN1 (ENST00000394374.6) at chr11:64803524-64810741 - Homo sapiens menin 1 (MEN1), transcript variant e1D, mRNA. (from RefSeq NM_130802)
MEN1 (ENST00000377321.5) at chr11:64803516-64810558 - Homo sapiens menin 1 (MEN1), transcript variant 8, mRNA. (from RefSeq NM_001370263)
MEN1 (ENST00000337652.5) at chr11:64803524-64811294 - Homo sapiens menin 1 (MEN1), transcript variant e1E, mRNA. (from RefSeq NM_130803)
WWP1 (ENST00000517970.6) at chr8:86342547-86468503 - Homo sapiens WW domain containing E3 ubiquitin protein ligase 1 (WWP1), mRNA. (from RefSeq NM_007013)
ACVR1B (ENST00000542485.1) at chr12:51953380-51994925 - Homo sapiens activin A receptor type 1B (ACVR1B), transcript variant 2, mRNA. (from RefSeq NM_020327)
ACVR1B (ENST00000541224.5) at chr12:51951701-51994217 - Homo sapiens activin A receptor type 1B (ACVR1B), transcript variant 3, mRNA. (from RefSeq NM_020328)
ACVR1B (ENST00000257963.9) at chr12:51951699-51997078 - Homo sapiens activin A receptor type 1B (ACVR1B), transcript variant 1, mRNA. (from RefSeq NM_004302)
MEN1 (ENST00000377326.7) at chr11:64803516-64810608 - Essential component of a MLL/SET1 histone  methyltransferase (HMT) complex, a complex that specifically  methylates 'Lys-4' of histone H3 (H3K4). Functions as a  transcriptional regulator. Binds to the TERT promoter and  represses telomerase expression. Plays a role in TGFB1-mediated  inhibition of cell-proliferation, possibly regulating SMAD3  transcriptional activity. Represses JUND-mediated transcriptional  activation on AP1 sites, as well as that mediated by NFKB subunit  RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be  involved in normal hematopoiesis through the activation of HOXA9  expression (By similarity). May be involved in DNA repair. (from UniProt O00255)
MEN1 (ENST00000377313.6) at chr11:64803514-64810132 - Essential component of a MLL/SET1 histone  methyltransferase (HMT) complex, a complex that specifically  methylates 'Lys-4' of histone H3 (H3K4). Functions as a  transcriptional regulator. Binds to the TERT promoter and  represses telomerase expression. Plays a role in TGFB1-mediated  inhibition of cell-proliferation, possibly regulating SMAD3  transcriptional activity. Represses JUND-mediated transcriptional  activation on AP1 sites, as well as that mediated by NFKB subunit  RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be  involved in normal hematopoiesis through the activation of HOXA9  expression (By similarity). May be involved in DNA repair. (from UniProt O00255)
DAB2 (ENST00000545653.5) at chr5:39371675-39425233 - Homo sapiens DAB adaptor protein 2 (DAB2), transcript variant 2, mRNA. (from RefSeq NM_001244871)
ADAMTSL2 (ENST00000651351.1) at chr9:133534704-133575519 - Homo sapiens ADAMTS like 2 (ADAMTSL2), transcript variant 1, mRNA. (from RefSeq NM_014694)
SMAD3 (ENST00000540846.6) at chr15:67125716-67190762 - Homo sapiens SMAD family member 3 (SMAD3), transcript variant 2, mRNA. (from RefSeq NM_001145102)
SMAD3 (ENST00000537194.6) at chr15:67166019-67190762 - Homo sapiens SMAD family member 3 (SMAD3), transcript variant 4, mRNA. (from RefSeq NM_001145104)
SMAD3 (ENST00000439724.7) at chr15:67138001-67190894 - Homo sapiens SMAD family member 3 (SMAD3), transcript variant 3, mRNA. (from RefSeq NM_001145103)
DAB2 (ENST00000320816.11) at chr5:39371677-39424980 - Homo sapiens DAB adaptor protein 2 (DAB2), transcript variant 1, mRNA. (from RefSeq NM_001343)
ADAMTSL2 (ENST00000354484.8) at chr9:133532164-133575519 - Homo sapiens ADAMTS like 2 (ADAMTSL2), transcript variant 2, mRNA. (from RefSeq NM_001145320)
SMAD3 (ENST00000327367.9) at chr15:67065602-67195169 - Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA. (from RefSeq NM_005902)
MED15 (ENST00000382974.6) at chr22:20507641-20586867 - Homo sapiens mediator complex subunit 15 (MED15), transcript variant 5, mRNA. (from RefSeq NM_001293236)
MED15 (ENST00000292733.11) at chr22:20507602-20587632 - Homo sapiens mediator complex subunit 15 (MED15), transcript variant 2, mRNA. (from RefSeq NM_015889)
MED15 (ENST00000263205.11) at chr22:20507610-20587619 - Homo sapiens mediator complex subunit 15 (MED15), transcript variant 1, mRNA. (from RefSeq NM_001003891)
PRDM16 (ENST00000378391.6) at chr1:3069197-3435421 - Homo sapiens PR/SET domain 16 (PRDM16), transcript variant 2, mRNA. (from RefSeq NM_199454)
PRDM16 (ENST00000270722.10) at chr1:3069203-3438621 - Homo sapiens PR/SET domain 16 (PRDM16), transcript variant 1, mRNA. (from RefSeq NM_022114)
SMAD4 (ENST00000342988.7) at chr18:51030213-51085039 - Homo sapiens SMAD family member 4 (SMAD4), mRNA. (from RefSeq NM_005359)
CREBBP (ENST00000262367.9) at chr16:3725054-3880726 - Homo sapiens CREB binding protein (CREBBP), transcript variant 1, mRNA. (from RefSeq NM_004380)
CREBBP (ENST00000382070.7) at chr16:3727539-3880120 - Homo sapiens CREB binding protein (CREBBP), transcript variant 2, mRNA. (from RefSeq NM_001079846)
CITED2 (ENST00000618718.1) at chr6:139373074-139374605 - Transcriptional coactivator of the p300/CBP-mediated  trancription complex. Acts as a bridge, linking TFAP2  transcription factors and the p300/CBP transcriptional coactivator  complex in order to stimulate TFAP2-mediated transcriptional  activation. Positively regulates TGF-beta signaling through its  association with the SMAD/p300/CBP-mediated transcriptional  coactivator complex. Stimulates the peroxisome proliferator-  activated receptors PPARA transcriptional activity. Enhances  estrogen-dependent transactivation mediated by estrogen receptors.  Acts also as a transcriptional corepressor; interferes with the  binding of the transcription factors HIF1A or STAT2 and the  p300/CBP transcriptional coactivator complex. Participates in sex  determination and early gonad development by stimulating  transcription activation of SRY. Plays a role in controlling left-  right patterning during embryogenesis; potentiates transcriptional  activation of NODAL-mediated gene transcription in the left  lateral plate mesoderm (LPM). Plays an essential role in  differentiation of the adrenal cortex from the adrenogonadal  primordium (AGP); stimulates WT1-mediated transcription activation  thereby up-regulating the nuclear hormone receptor NR5A1 promoter  activity. Associates with chromatin to the PITX2 P1 promoter  region. (from UniProt Q99967)
HGS (ENST00000329138.9) at chr17:81684011-81702121 - Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), mRNA. (from RefSeq NM_004712)
TP63 (ENST00000456148.1) at chr3:189789801-189894502 - Acts as a sequence specific DNA binding transcriptional  activator or repressor. The isoforms contain a varying set of  transactivation and auto-regulating transactivation inhibiting  domains thus showing an isoform specific activity. Isoform 2  activates RIPK4 transcription. May be required in conjunction with  TP73/p73 for initiation of p53/TP53 dependent apoptosis in  response to genotoxic insults and the presence of activated  oncogenes. Involved in Notch signaling by probably inducing JAG1  and JAG2. Plays a role in the regulation of epithelial  morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may  govern the maintenance of epithelial stem cell compartments and  regulate the initiation of epithelial stratification from the  undifferentiated embryonal ectoderm. Required for limb formation  from the apical ectodermal ridge. Activates transcription of the  p21 promoter. (from UniProt Q9H3D4)
HIPK2 (ENST00000428878.6) at chr7:139572629-139777778 - Homo sapiens homeodomain interacting protein kinase 2 (HIPK2), transcript variant 2, mRNA. (from RefSeq NM_001113239)
HIPK2 (ENST00000406875.8) at chr7:139561570-139777998 - Homo sapiens homeodomain interacting protein kinase 2 (HIPK2), transcript variant 1, mRNA. (from RefSeq NM_022740)
TP63 (ENST00000449992.5) at chr3:189789801-189894502 - Homo sapiens tumor protein p63 (TP63), transcript variant 9, mRNA. (from RefSeq NM_001329146)
TP63 (ENST00000440651.6) at chr3:189631516-189894502 - Homo sapiens tumor protein p63 (TP63), transcript variant 10, mRNA. (from RefSeq NM_001329148)
TP63 (ENST00000392461.7) at chr3:189789801-189894231 - Homo sapiens tumor protein p63 (TP63), transcript variant 12, mRNA. (from RefSeq NM_001329150)
TP63 (ENST00000320472.9) at chr3:189631488-189894702 - Homo sapiens tumor protein p63 (TP63), transcript variant 7, mRNA. (from RefSeq NM_001329144)
TP63 (ENST00000264731.8) at chr3:189631389-189897276 - Homo sapiens tumor protein p63 (TP63), transcript variant 1, mRNA. (from RefSeq NM_003722)
TP63 (ENST00000437221.5) at chr3:189789801-189881496 - Homo sapiens tumor protein p63 (TP63), transcript variant 6, mRNA. (from RefSeq NM_001114982)
TP63 (ENST00000418709.6) at chr3:189631488-189881496 - Homo sapiens tumor protein p63 (TP63), transcript variant 3, mRNA. (from RefSeq NM_001114979)
TP63 (ENST00000392463.6) at chr3:189789801-189894221 - Homo sapiens tumor protein p63 (TP63), transcript variant 5, mRNA. (from RefSeq NM_001114981)
TP63 (ENST00000392460.7) at chr3:189631516-189894221 - Homo sapiens tumor protein p63 (TP63), transcript variant 2, mRNA. (from RefSeq NM_001114978)
TP63 (ENST00000354600.9) at chr3:189789660-189897268 - Homo sapiens tumor protein p63 (TP63), transcript variant 4, mRNA. (from RefSeq NM_001114980)
ACVR2B (ENST00000352511.5) at chr3:38453890-38493142 - Homo sapiens activin A receptor type 2B (ACVR2B), mRNA. (from RefSeq NM_001106)
RHOA (ENST00000418115.6) at chr3:49359145-49411976 - Homo sapiens ras homolog family member A (RHOA), transcript variant 1, mRNA. (from RefSeq NM_001664)
PML (ENST00000564428.5) at chr15:73994744-74043338 - Homo sapiens promyelocytic leukemia (PML), transcript variant 10, mRNA. (from RefSeq NM_033249)
PML (ENST00000436891.7) at chr15:73994744-74036394 - Homo sapiens promyelocytic leukemia (PML), transcript variant 5, mRNA. (from RefSeq NM_033244)
PML (ENST00000435786.6) at chr15:73994744-74036394 - Homo sapiens promyelocytic leukemia (PML), transcript variant 2, mRNA. (from RefSeq NM_033240)
PML (ENST00000395135.7) at chr15:73994673-74043337 - Homo sapiens promyelocytic leukemia (PML), transcript variant 6, mRNA. (from RefSeq NM_002675)
PML (ENST00000395132.6) at chr15:73994717-74036394 - Homo sapiens promyelocytic leukemia (PML), transcript variant 8, mRNA. (from RefSeq NM_033247)
PML (ENST00000359928.8) at chr15:73994744-74043338 - Homo sapiens promyelocytic leukemia (PML), transcript variant 7, mRNA. (from RefSeq NM_033246)
PML (ENST00000354026.10) at chr15:73994717-74036394 - Homo sapiens promyelocytic leukemia (PML), transcript variant 11, mRNA. (from RefSeq NM_033250)
PML (ENST00000268059.10) at chr15:73994717-74036394 - Homo sapiens promyelocytic leukemia (PML), transcript variant 9, mRNA. (from RefSeq NM_033239)
PML (ENST00000268058.8) at chr15:73994716-74047827 - Homo sapiens promyelocytic leukemia (PML), transcript variant 1, mRNA. (from RefSeq NM_033238)
PML (ENST00000569477.5) at chr15:73994731-74035590 - Key component of PML nuclear bodies that regulate a  large number of cellular processes by facilitating post-  translational modification of target proteins, promoting protein-  protein contacts, or by sequestering proteins. Functions as tumor  suppressor. Required for normal, caspase-dependent apoptosis in  response to DNA damage, FAS, TNF, or interferons. Plays a role in  transcription regulation, DNA damage response, DNA repair and  chromatin organization. Plays a role in processes regulated by  retinoic acid, regulation of cell division, terminal  differentiation of myeloid precursor cells and differentiation of  neural progenitor cells. Required for normal immunity to microbial  infections. Plays a role in antiviral response. In the cytoplasm,  plays a role in TGFB1-dependent processes. Regulates p53/TP53  levels by inhibiting its ubiquitination and proteasomal  degradation. Regulates activation of p53/TP53 via phosphorylation  at 'Ser-20'. Sequesters MDM2 in the nucleolus after DNA damage,  and thereby inhibits ubiquitination and degradation of p53/TP53.  Regulates translation of HIF1A by sequestering MTOR, and thereby  plays a role in neoangiogenesis and tumor vascularization.  Regulates RB1 phosphorylation and activity. Required for normal  development of the brain cortex during embryogenesis. Can  sequester herpes virus and varicella virus proteins inside PML  bodies, and thereby inhibit the formation of infectious viral  particles. Regulates phosphorylation of ITPR3 and plays a role in  the regulation of calcium homeostasis at the endoplasmic reticulum  (By similarity). Regulates transcription activity of ELF4.  Inhibits specifically the activity of the tetrameric form of PKM.  Together with SATB1, involved in local chromatin-loop remodeling  and gene expression regulation at the MHC-I locus. Regulates PTEN  compartmentalization through the inhibition of USP7-mediated  deubiquitination. (from UniProt P29590)
PML (ENST00000569965.5) at chr15:73994733-74043338 - Key component of PML nuclear bodies that regulate a  large number of cellular processes by facilitating post-  translational modification of target proteins, promoting protein-  protein contacts, or by sequestering proteins. Functions as tumor  suppressor. Required for normal, caspase-dependent apoptosis in  response to DNA damage, FAS, TNF, or interferons. Plays a role in  transcription regulation, DNA damage response, DNA repair and  chromatin organization. Plays a role in processes regulated by  retinoic acid, regulation of cell division, terminal  differentiation of myeloid precursor cells and differentiation of  neural progenitor cells. Required for normal immunity to microbial  infections. Plays a role in antiviral response. In the cytoplasm,  plays a role in TGFB1-dependent processes. Regulates p53/TP53  levels by inhibiting its ubiquitination and proteasomal  degradation. Regulates activation of p53/TP53 via phosphorylation  at 'Ser-20'. Sequesters MDM2 in the nucleolus after DNA damage,  and thereby inhibits ubiquitination and degradation of p53/TP53.  Regulates translation of HIF1A by sequestering MTOR, and thereby  plays a role in neoangiogenesis and tumor vascularization.  Regulates RB1 phosphorylation and activity. Required for normal  development of the brain cortex during embryogenesis. Can  sequester herpes virus and varicella virus proteins inside PML  bodies, and thereby inhibit the formation of infectious viral  particles. Regulates phosphorylation of ITPR3 and plays a role in  the regulation of calcium homeostasis at the endoplasmic reticulum  (By similarity). Regulates transcription activity of ELF4.  Inhibits specifically the activity of the tetrameric form of PKM.  Together with SATB1, involved in local chromatin-loop remodeling  and gene expression regulation at the MHC-I locus. Regulates PTEN  compartmentalization through the inhibition of USP7-mediated  deubiquitination. (from UniProt P29590)
PML (ENST00000567543.5) at chr15:73994744-74034558 - Key component of PML nuclear bodies that regulate a  large number of cellular processes by facilitating post-  translational modification of target proteins, promoting protein-  protein contacts, or by sequestering proteins. Functions as tumor  suppressor. Required for normal, caspase-dependent apoptosis in  response to DNA damage, FAS, TNF, or interferons. Plays a role in  transcription regulation, DNA damage response, DNA repair and  chromatin organization. Plays a role in processes regulated by  retinoic acid, regulation of cell division, terminal  differentiation of myeloid precursor cells and differentiation of  neural progenitor cells. Required for normal immunity to microbial  infections. Plays a role in antiviral response. In the cytoplasm,  plays a role in TGFB1-dependent processes. Regulates p53/TP53  levels by inhibiting its ubiquitination and proteasomal  degradation. Regulates activation of p53/TP53 via phosphorylation  at 'Ser-20'. Sequesters MDM2 in the nucleolus after DNA damage,  and thereby inhibits ubiquitination and degradation of p53/TP53.  Regulates translation of HIF1A by sequestering MTOR, and thereby  plays a role in neoangiogenesis and tumor vascularization.  Regulates RB1 phosphorylation and activity. Required for normal  development of the brain cortex during embryogenesis. Can  sequester herpes virus and varicella virus proteins inside PML  bodies, and thereby inhibit the formation of infectious viral  particles. Regulates phosphorylation of ITPR3 and plays a role in  the regulation of calcium homeostasis at the endoplasmic reticulum  (By similarity). Regulates transcription activity of ELF4.  Inhibits specifically the activity of the tetrameric form of PKM.  Together with SATB1, involved in local chromatin-loop remodeling  and gene expression regulation at the MHC-I locus. Regulates PTEN  compartmentalization through the inhibition of USP7-mediated  deubiquitination. (from UniProt P29590)
PML (ENST00000565898.5) at chr15:73994729-74047812 - Key component of PML nuclear bodies that regulate a  large number of cellular processes by facilitating post-  translational modification of target proteins, promoting protein-  protein contacts, or by sequestering proteins. Functions as tumor  suppressor. Required for normal, caspase-dependent apoptosis in  response to DNA damage, FAS, TNF, or interferons. Plays a role in  transcription regulation, DNA damage response, DNA repair and  chromatin organization. Plays a role in processes regulated by  retinoic acid, regulation of cell division, terminal  differentiation of myeloid precursor cells and differentiation of  neural progenitor cells. Required for normal immunity to microbial  infections. Plays a role in antiviral response. In the cytoplasm,  plays a role in TGFB1-dependent processes. Regulates p53/TP53  levels by inhibiting its ubiquitination and proteasomal  degradation. Regulates activation of p53/TP53 via phosphorylation  at 'Ser-20'. Sequesters MDM2 in the nucleolus after DNA damage,  and thereby inhibits ubiquitination and degradation of p53/TP53.  Regulates translation of HIF1A by sequestering MTOR, and thereby  plays a role in neoangiogenesis and tumor vascularization.  Regulates RB1 phosphorylation and activity. Required for normal  development of the brain cortex during embryogenesis. Can  sequester herpes virus and varicella virus proteins inside PML  bodies, and thereby inhibit the formation of infectious viral  particles. Regulates phosphorylation of ITPR3 and plays a role in  the regulation of calcium homeostasis at the endoplasmic reticulum  (By similarity). Regulates transcription activity of ELF4.  Inhibits specifically the activity of the tetrameric form of PKM.  Together with SATB1, involved in local chromatin-loop remodeling  and gene expression regulation at the MHC-I locus. Regulates PTEN  compartmentalization through the inhibition of USP7-mediated  deubiquitination. (from UniProt P29590)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_005901.5 at chr18:47833095-47930599
NM_001003652.3 at chr18:47833095-47931146
NM_001135937.2 at chr18:47833095-47931146

NCBI RefSeq genes, predicted subset (XM_* or XR_*)

XM_011525984.2 at chr18:47833103-47886884
XM_024451173.1 at chr18:47833103-47930594
XM_017025748.2 at chr18:47833103-47930845
XM_006722451.4 at chr18:47833103-47930872
XM_017025750.2 at chr18:47833103-47930872
XM_017025745.2 at chr18:47833103-47931188
XM_011525985.3 at chr18:47833103-47931188
XM_017025746.2 at chr18:47833103-47931188
XM_017025747.2 at chr18:47833103-47931188
XM_005258259.4 at chr18:47833104-47930880
XM_017025749.1 at chr18:47857376-47930534

NCBI RefSeq and Ensembl transcripts from the MANE Project (v0.6)

SMAD2 at chr18:47808957-47930659

RefSeq Genes

SMAD2 at chr18:47808957-47930659 - (NM_005901) mothers against decapentaplegic homolog 2 isoform 1
SMAD2 at chr18:47808957-47930872 - (NM_001003652) mothers against decapentaplegic homolog 2 isoform 1
SMAD2 at chr18:47833095-47931146 - (NM_001135937) mothers against decapentaplegic homolog 2 isoform 2

Non-Human RefSeq Genes

smad2 at chr18:47841725-47896759 - (NM_001011168) mothers against decapentaplegic homolog 2
SMAD2 at chr18:47841315-47931143 - (NM_001266803) mothers against decapentaplegic homolog 2
SMAD2 at chr18:47841771-47896757 - (NM_001256148) mothers against decapentaplegic homolog 2
SMAD2 at chr18:47841245-47930511 - (NM_001132904) mothers against decapentaplegic homolog 2
SMAD2 at chr18:47841248-47896804 - (NM_001046218) mothers against decapentaplegic homolog 2
Smad2 at chr18:47833369-47931081 - (NM_010754) mothers against decapentaplegic homolog 2 isoform 1
Smad2 at chr18:47833369-47896797 - (NM_001252481) mothers against decapentaplegic homolog 2 isoform 1
Smad2 at chr18:47840826-47930950 - (NM_001277450) mothers against decapentaplegic homolog 2
Smad2 at chr18:47840826-47930450 - (NM_019191) mothers against decapentaplegic homolog 2
Smad2 at chr18:47833369-47896797 - (NM_001311070) mothers against decapentaplegic homolog 2 isoform 2
smad2 at chr18:47841827-47896762 - (NM_001290015) mothers against decapentaplegic homolog 2
smad2 at chr15:67066123-67190536 - (NM_001290015) mothers against decapentaplegic homolog 2
smad2 at chr18:47841827-47896762 - (NM_131366) mothers against decapentaplegic homolog 2
smad2 at chr15:67066123-67190536 - (NM_131366) mothers against decapentaplegic homolog 2
smad2.S at chr18:47841827-47896759 - (NM_001091495) SMAD family member 2 S homeolog
SMAD2Z at chr18:47841725-47896757 - (NM_204561) mothers against decapentaplegic homolog 2
LOC100178575 at chr18:47841827-47896744 - (NM_001078349) Smad2/3b protein
smad2/3a at chr18:47841827-47865134 - (NM_001078348) Smad2/3a protein
LOC101867532 at chr15:67066149-67190536 - (NM_001281308) Smad2a
LOC101268919 at chr18:47841827-47896756 - (NM_001281334) Smad2b
LOC101268919 at chr15:67066155-67190536 - (NM_001281334) Smad2b
Smad2/3 at chr18:47841827-47896759 - (NM_001168186) Smad2/3 transcription factor
Smad2/3 at chr15:67066155-67190536 - (NM_001168186) Smad2/3 transcription factor

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

SMAD2 at chr18:47808957-47930659
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

SMAD2 at chr18:47808957-47930659
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

SMAD2 at chr18:47808957-47930559
SMAD2 at chr18:47831551-47931141
SMAD2 at chr18:47833096-47931146
SMAD2 at chr18:47841225-47896811
SMAD2 at chr18:47844912-47930842
SMAD2 at chr18:47868263-47886923
SMAD2 at chr18:47868326-47930599
SMAD2 at chr18:47868327-47930837
SMAD2 at chr18:47869352-47930362
SMAD2 at chr18:47869422-47895725
SMAD2 at chr18:47870473-47930855
SMAD2 at chr18:47870475-47923642

International Knockout Mouse Consortium Genes Mapped to Human Genome

Smad2_118421 at chr18:47833095-47931144
Smad2_46953 at chr18:47833095-47931144
Smad2_76533 at chr18:47833095-47931144

Human Aligned mRNA Search Results

AF027964 - Homo sapiens MAD-related protein Smad2 mRNA, complete cds.
BC014840 - Homo sapiens SMAD family member 2, mRNA (cDNA clone MGC:22139 IMAGE:4449540), complete cds.
BC025699 - Homo sapiens SMAD family member 2, mRNA (cDNA clone MGC:34440 IMAGE:5221801), complete cds.

Non-Human Aligned mRNA Search Results

MK356389 - Strongylocentrotus intermedius smad2-3 mRNA, complete cds.
MK356390 - Mesocentrotus nudus smad2-3 mRNA, complete cds.
BC165346 - Danio rerio MAD homolog 2 (Drosophila), mRNA (cDNA clone MGC:192434 IMAGE:100060880), complete cds.
HQ184937 - Oncorhynchus mykiss Smad2a mRNA, complete cds.
HQ184936 - Oncorhynchus mykiss Smad2b mRNA, complete cds.
AF230190 - Gallus gallus TGF effector Smad2 mRNA, partial cds.
AF229022 - Danio rerio transcription factor Smad2 mRNA, complete cds.
JP287013 - TSA: Pipa carvalhoi Pipa_carvalhoi.contig1053 mRNA sequence.
AY334552 - Mus musculus SMAD2 delta-exon3 isoform mRNA, complete cds, alternatively spliced.
AB017912 - Rattus norvegicus mRNA for Smad2 protein, complete cds.
AF056001 - Rattus norvegicus Smad2 protein (Smad2) mRNA, complete cds.
BC089184 - Mus musculus MAD homolog 2 (Drosophila), mRNA (cDNA clone MGC:102511 IMAGE:5322611), complete cds.
AF168774 - Danio rerio Smad2 protein (smad2) mRNA, complete cds.
BC123801 - Bos taurus SMAD family member 2, mRNA (cDNA clone MGC:143023 IMAGE:8308175), complete cds.
MF967590 - Hemicentrotus pulcherrimus SMAD2/3 mRNA, complete cds.
AF101386 - Drosophila melanogaster transcription factor SMAD2 (smad2) mRNA, complete cds.
JN380193 - Mnemiopsis leidyi Smad2 mRNA, complete cds.
AF215934 - Schistosoma mansoni Smad2 (Smad2) mRNA, complete cds.
KY328719 - Helicoverpa armigera Smad2 mRNA, complete cds.
AB071949 - Equus caballus mRNA for Smad2, partial cds.
AF508025 - Ovis aries Smad2 mRNA, partial cds.
AY185300 - Ovis aries Smad2 mRNA, partial cds.
AB010147 - Rattus norvegicus mRNA for Smad2, complete cds.
EF043881 - Synthetic construct clone ATCC 10374419 Smad2 mRNA, complete cds.
DQ912858 - Ctenopharyngodon idella Smad2 mRNA, complete cds.
KC986816 - Eleutherodactylus coqui clone B Smad2 mRNA, complete cds, alternatively spliced.
KC986817 - Eleutherodactylus coqui clone 3 Smad2 mRNA, complete cds, alternatively spliced.
AY550112 - Carassius auratus Smad2 mRNA, complete cds.
KT383019 - Ambystoma mexicanum Smad2 mRNA, complete cds.
JN032010 - Trichinella spiralis smad2 mRNA, complete cds.
AB267397 - Strongylocentrotus purpuratus mRNA for Sp-Smad2/3, complete cds.
AB210687 - Ciona intestinalis mRNA for Smad2/3b, complete cds, clone: cilv057j23.
AB210686 - Ciona intestinalis mRNA for Smad2/3a, complete cds, clone: cima815d13.
KJ658756 - Hofstenia miamia smad2/3 mRNA, complete cds.
HQ588924 - Branchiostoma belcheri tsingtauense Smad2/3 mRNA, complete cds.
KC161225 - Schmidtea mediterranea Smad2/3 mRNA, partial cds.
MF589730 - Oopsacas minuta Smad2/3 mRNA, complete cds.
GU076121 - Saccoglossus kowalevskii Smad2/3 transcription factor mRNA, complete cds.
AY915914 - Schistosoma japonicum TGF-beta signal transducer Smad2 mRNA, partial cds.
AF232025 - Schistosoma mansoni TGF-beta signal transducer Smad2 (Smad2) mRNA, complete cds.
DQ432067 - Bos taurus mothers against DPP homolog 2 (Drosophila) (SMAD2) mRNA, complete cds.
FM995263 - Sus scrofa partial mRNA for SMAD family member 2 (SMAD2 gene).
JT416142 - TSA: Ictalurus punctatus aby_k57:961285 mRNA sequence.
JU319695 - TSA: Macaca mulatta Mamu_501311 mRNA sequence.
JU334506 - TSA: Macaca mulatta Mamu_501310 mRNA sequence.
JU334507 - TSA: Macaca mulatta Mamu_501312 mRNA sequence.
JU475607 - TSA: Macaca mulatta Mamu_369364 mRNA sequence.
JU475608 - TSA: Macaca mulatta Mamu_369365 mRNA sequence.
JV047059 - TSA: Macaca mulatta Mamu_437935 mRNA sequence.
HQ687751 - Sus scrofa mothers against decapentaplegic-like 2 (Smad2) mRNA, complete cds, alternatively spliced.
HQ687752 - Sus scrofa mothers against decapentaplegic-like 2 transcript variant 1 (Smad2) mRNA, complete cds, alternatively spliced.
KU820913 - Sus scrofa breed Bamei Black pig SMAD family member 2 (Smad2) mRNA, complete cds.
BC021342 - Mus musculus MAD homolog 2 (Drosophila), mRNA (cDNA clone MGC:29095 IMAGE:5066237), complete cds.
BC127497 - Rattus norvegicus SMAD family member 2, mRNA (cDNA clone MGC:156656 IMAGE:8364718), complete cds.
MG134350 - Synthetic construct Xenopus tropicalis clone IMAGE:6991760 SMAD family member 2 (smad2) gene, encodes complete protein.
CR761970 - Xenopus tropicalis finished cDNA, clone TNeu107i17.
BC044338 - Danio rerio MAD homolog 2 (Drosophila), mRNA (cDNA clone MGC:55212 IMAGE:2641434), complete cds.
KU847979 - Rana sylvatica SMAD family member 2 (smad2) mRNA, partial cds.
BC084994 - Xenopus tropicalis SMAD family member 2, mRNA (cDNA clone MGC:89473 IMAGE:6991760), complete cds.
BC097043 - Danio rerio MAD homolog 2 (Drosophila), mRNA (cDNA clone MGC:113963 IMAGE:7395088), complete cds.

GeneReviews

SMAD2 at chr18:47808957-47930659