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Gencode Genes

PPP1R15A (ENST00000200453.6) at chr19:48872421-48876058 - <b>PPP1R15A</b> ENST00000200453.6 Homo sapiens protein phosphatase 1 regulatory subunit 15A 
PPP1R1A (ENST00000257905.13) at chr12:54579246-54588659 -  ... calcineurin or PP2B Does not inhibit type-2 phosphatases Interacts with <b>PPP1R15A</b> O75807 PPP1R15A NbExp 4 IntAct EBI-1568511 EBI-714746 Phosphorylation of 
BAG1 (ENST00000634734.3) at chr9:33252471-33264708 -  ... HSC70 by promoting substrate release Inhibits the pro-apoptotic function of <b>PPP1R15A</b> and has anti-apoptotic activity Markedly increases the anti-cell death 
SMAD7 (ENST00000262158.8) at chr18:48919853-48950965 -  ... to the TGF-beta receptor complex Also acts by recruiting the <b>PPP1R15A</b> PP1 complex to TGFBR1 which promotes its dephosphorylation Positively 
CTBP2 (ENST00000309035.11) at chr10:124984317-125028071 -  ... EBI-741533 EBI-741406 Q14526 HIC1 NbExp 2 IntAct EBI-741533 EBI-2507362 O75807 <b>PPP1R15A</b> NbExp 2 IntAct EBI-741533 EBI-714746 Q92786 PROX1 NbExp 2 
PPP1CC (ENST00000335007.10) at chr12:110719680-110742891 -  ... Inactivated by binding to URI1 The phosphatase activity of the <b>PPP1R15A-PP1</b> complex toward EIF2S1 is specifically inhibited by Salubrinal a 
KMT2A (ENST00000534358.8) at chr11:118436492-118526832 -  ... acetylated on Lys-9 Required for transcriptional activation of HOXA9 Promotes <b>PPP1R15A-induced</b> apoptosis S-adenosyl-L-methionine L-lysine histone S-adenosyl-L-homocysteine N 6 methyl-L-lysine histone 
PPP1CA (ENST00000376745.9) at chr11:67398183-67401858 -  ... 1 manganese ion per subunit The phosphatase activity of the <b>PPP1R15A-PP1</b> complex toward EIF2S1 is specifically inhibited by Salubrinal a 
PCNA (ENST00000379143.10) at chr20:5114953-5119958 -  ... complex with DNTTIP2 and core histone Interacts with KCTD10 and <b>PPP1R15A</b> By similarity Interacts with POLD1 POLD3 and POLD4 Interacts 
SMARCB1 (ENST00000644036.2) at chr22:23786966-23838009 -  ... to double-stranded DNA Interacts with MYK and MAEL Interacts with <b>PPP1R15A</b> Binds tightly to the human immunodeficiency virus-type 1 HIV-1 
LYN (ENST00000519728.6) at chr8:55879835-56014169 -  ... CD19 CD22 CD79A and CD79B Interacts via SH3 domain with <b>PPP1R15A</b> and PDE4A Interacts with TGFB1I1 Interacts via SH3 domain 
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