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Gencode Genes

PIK3CA (ENST00000263967.4) at chr3:179148357-179240093 - Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), mRNA. (from RefSeq NM_006218)
PIK3CA (ENST00000643187.1) at chr3:179148574-179235098 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (from HGNC PIK3CA)
PIK3CA (ENST00000477735.1) at chr3:179148114-179198888 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt C9J951)
PIK3CA (ENST00000468036.1) at chr3:179149527-179199179 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt C9JAM9)
PIK3CA (ENST00000462255.1) at chr3:179219551-179226017 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (from HGNC PIK3CA)
MTFP1 (ENST00000355143.8) at chr22:30425776-30429053 - Homo sapiens mitochondrial fission process 1 (MTFP1), transcript variant 2, mRNA. (from RefSeq NM_001003704)
MTFP1 (ENST00000266263.10) at chr22:30425768-30429054 - Homo sapiens mitochondrial fission process 1 (MTFP1), transcript variant 1, mRNA. (from RefSeq NM_016498)
APPL1 (ENST00000288266.8) at chr3:57227729-57273471 - Homo sapiens adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), mRNA. (from RefSeq NM_012096)
PIK3R2 (ENST00000617130.4) at chr19:18155880-18169294 - Binds to activated (phosphorylated) protein-tyrosine  kinases, through its SH2 domain, and acts as an adapter, mediating  the association of the p110 catalytic unit to the plasma membrane. (from UniProt O00459)
RIT2 (ENST00000589109.5) at chr18:42743227-43115691 - Homo sapiens Ras like without CAAX 2 (RIT2), transcript variant 2, mRNA. (from RefSeq NM_001272077)
RIT2 (ENST00000326695.10) at chr18:42743227-43115685 - Homo sapiens Ras like without CAAX 2 (RIT2), transcript variant 1, mRNA. (from RefSeq NM_002930)
UBTF (ENST00000533177.5) at chr17:44206595-44219121 - Recognizes the ribosomal RNA gene promoter and activates  transcription mediated by RNA polymerase I through cooperative  interactions with the transcription factor SL1/TIF-IB complex. It  binds specifically to the upstream control element. (from UniProt P17480)
UBTF (ENST00000529383.5) at chr17:44207240-44218502 - Recognizes the ribosomal RNA gene promoter and activates  transcription mediated by RNA polymerase I through cooperative  interactions with the transcription factor SL1/TIF-IB complex. It  binds specifically to the upstream control element. (from UniProt P17480)
UBTF (ENST00000526094.5) at chr17:44207240-44218502 - Recognizes the ribosomal RNA gene promoter and activates  transcription mediated by RNA polymerase I through cooperative  interactions with the transcription factor SL1/TIF-IB complex. It  binds specifically to the upstream control element. (from UniProt P17480)
APPL1 (ENST00000650354.1) at chr3:57227726-57278105 - Required for the regulation of cell proliferation in  response to extracellular signals from an early endosomal  compartment. Links Rab5 to nuclear signal transduction. (from UniProt Q9UKG1)
PIK3R3 (ENST00000372006.5) at chr1:46040140-46132794 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3), transcript variant 4, mRNA. (from RefSeq NM_001303428)
PIK3R3 (ENST00000423209.5) at chr1:46043662-46132616 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3), transcript variant 5, mRNA. (from RefSeq NM_001303429)
PIK3R3 (ENST00000420542.5) at chr1:46040142-46133036 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3), transcript variant 7, mRNA. (from RefSeq NM_001328649)
RUFY3 (ENST00000502653.5) at chr4:70734434-70807102 - Homo sapiens RUN and FYVE domain containing 3 (RUFY3), transcript variant 4, mRNA. (from RefSeq NM_001291993)
PIK3R3 (ENST00000262741.10) at chr1:46040140-46132629 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3), transcript variant 14, non-coding RNA. (from RefSeq NR_137329)
RUFY3 (ENST00000226328.8) at chr4:70722011-70793557 - Homo sapiens RUN and FYVE domain containing 3 (RUFY3), transcript variant 2, mRNA. (from RefSeq NM_014961)
RUFY3 (ENST00000381006.8) at chr4:70721964-70808619 - Homo sapiens RUN and FYVE domain containing 3 (RUFY3), transcript variant 1, mRNA. (from RefSeq NM_001037442)
RUFY3 (ENST00000417478.6) at chr4:70704801-70790082 - Homo sapiens RUN and FYVE domain containing 3 (RUFY3), transcript variant 3, mRNA. (from RefSeq NM_001130709)
RIT1 (ENST00000368322.7) at chr1:155900274-155910915 - Homo sapiens Ras like without CAAX 1 (RIT1), transcript variant 1, mRNA. (from RefSeq NM_001256821)
RIT1 (ENST00000539040.5) at chr1:155900183-155911402 - Homo sapiens Ras like without CAAX 1 (RIT1), transcript variant 3, mRNA. (from RefSeq NM_001256820)
RIT1 (ENST00000368323.8) at chr1:155897808-155911349 - Homo sapiens Ras like without CAAX 1 (RIT1), transcript variant 2, mRNA. (from RefSeq NM_006912)
HRAS (ENST00000493230.5) at chr11:532242-535538 - Ras proteins bind GDP/GTP and possess intrinsic GTPase  activity. (from UniProt P01112)
HRAS (ENST00000397594.5) at chr11:532242-534375 - Ras proteins bind GDP/GTP and possess intrinsic GTPase  activity. (from UniProt P01112)
HRAS (ENST00000634098.1) at chr11_KI270832v1_alt:61883-65179 - Ras proteins bind GDP/GTP and possess intrinsic GTPase  activity. (from UniProt P01112)
HRAS (ENST00000631967.1) at chr11_KI270832v1_alt:61883-64016 - Ras proteins bind GDP/GTP and possess intrinsic GTPase  activity. (from UniProt P01112)
PIK3R1 (ENST00000521657.5) at chr5:68215776-68298753 - Binds to activated (phosphorylated) protein-Tyr kinases,  through its SH2 domain, and acts as an adapter, mediating the  association of the p110 catalytic unit to the plasma membrane.  Necessary for the insulin-stimulated increase in glucose uptake  and glycogen synthesis in insulin-sensitive tissues. Plays an  important role in signaling in response to FGFR1, FGFR2, FGFR3,  FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role  in ITGB2 signaling. (from UniProt P27986)
UBTF (ENST00000302904.8) at chr17:44205033-44221626 - Homo sapiens upstream binding transcription factor (UBTF), transcript variant 4, non-coding RNA. (from RefSeq NR_045058)
UBTF (ENST00000393606.7) at chr17:44207116-44219750 - Homo sapiens upstream binding transcription factor (UBTF), transcript variant 3, mRNA. (from RefSeq NM_001076684)
UBTF (ENST00000343638.9) at chr17:44205033-44220963 - Homo sapiens upstream binding transcription factor (UBTF), transcript variant 2, mRNA. (from RefSeq NM_001076683)
UBTF (ENST00000436088.6) at chr17:44205040-44219675 - Homo sapiens upstream binding transcription factor (UBTF), transcript variant 1, mRNA. (from RefSeq NM_014233)
PIK3R1 (ENST00000523872.1) at chr5:68292568-68298756 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1), transcript variant 4, mRNA. (from RefSeq NM_001242466)
PIK3R1 (ENST00000336483.9) at chr5:68290637-68298583 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1), transcript variant 2, mRNA. (from RefSeq NM_181504)
PIK3R1 (ENST00000320694.12) at chr5:68288368-68298583 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1), transcript variant 3, mRNA. (from RefSeq NM_181524)
PIK3R1 (ENST00000521381.6) at chr5:68215756-68301821 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1), transcript variant 1, mRNA. (from RefSeq NM_181523)
PIK3R2 (ENST00000222254.13) at chr19:18153163-18170532 - Homo sapiens phosphoinositide-3-kinase regulatory subunit 2 (PIK3R2), transcript variant 3, non-coding RNA. (from RefSeq NR_162071)
IRS1 (ENST00000305123.5) at chr2:226731317-226799759 - Homo sapiens insulin receptor substrate 1 (IRS1), mRNA. (from RefSeq NM_005544)
RASD2 (ENST00000216127.5) at chr22:35540831-35553999 - Homo sapiens RASD family member 2 (RASD2), transcript variant 1, mRNA. (from RefSeq NM_014310)
HRAS (ENST00000616241.4) at chr11_KI270832v1_alt:61884-65191 - Homo sapiens HRas proto-oncogene, GTPase (HRAS), transcript variant 2, mRNA. (from RefSeq NM_176795)
HRAS (ENST00000417302.5) at chr11:532243-535550 - Homo sapiens HRas proto-oncogene, GTPase (HRAS), transcript variant 2, mRNA. (from RefSeq NM_176795)
SRC (ENST00000373578.6) at chr20:37346154-37406050 - Homo sapiens SRC proto-oncogene, non-receptor tyrosine kinase (SRC), transcript variant 2, mRNA. (from RefSeq NM_198291)
AKT2 (ENST00000392038.7) at chr19:40230317-40285345 - Homo sapiens AKT serine/threonine kinase 2 (AKT2), transcript variant 1, mRNA. (from RefSeq NM_001626)
AKT2 (ENST00000424901.5) at chr19:40230318-40285395 - Homo sapiens AKT serine/threonine kinase 2 (AKT2), transcript variant 4, mRNA. (from RefSeq NM_001330511)
AKT1 (ENST00000555528.5) at chr14:104769371-104793700 - Homo sapiens AKT serine/threonine kinase 1 (AKT1), transcript variant 1, mRNA. (from RefSeq NM_005163)
AKT1 (ENST00000349310.7) at chr14:104769349-104795751 - Homo sapiens AKT serine/threonine kinase 1 (AKT1), transcript variant 2, mRNA. (from RefSeq NM_001014432)
AKT1 (ENST00000407796.6) at chr14:104769349-104795679 - Homo sapiens AKT serine/threonine kinase 1 (AKT1), transcript variant 3, mRNA. (from RefSeq NM_001014431)
SRC (ENST00000373567.6) at chr20:37383668-37406050 - Non-receptor protein tyrosine kinase which is activated  following engagement of many different classes of cellular  receptors including immune response receptors, integrins and other  adhesion receptors, receptor protein tyrosine kinases, G protein-  coupled receptors as well as cytokine receptors. Participates in  signaling pathways that control a diverse spectrum of biological  activities including gene transcription, immune response, cell  adhesion, cell cycle progression, apoptosis, migration, and  transformation. Due to functional redundancy between members of  the SRC kinase family, identification of the specific role of each  SRC kinase is very difficult. SRC appears to be one of the primary  kinases activated following engagement of receptors and plays a  role in the activation of other protein tyrosine kinase (PTK)  families. Receptor clustering or dimerization leads to recruitment  of SRC to the receptor complexes where it phosphorylates the  tyrosine residues within the receptor cytoplasmic domains. Plays  an important role in the regulation of cytoskeletal organization  through phosphorylation of specific substrates such as AFAP1.  Phosphorylation of AFAP1 allows the SRC SH2 domain to bind AFAP1  and to localize to actin filaments. Cytoskeletal reorganization is  also controlled through the phosphorylation of cortactin (CTTN).  When cells adhere via focal adhesions to the extracellular matrix,  signals are transmitted by integrins into the cell resulting in  tyrosine phosphorylation of a number of focal adhesion proteins,  including PTK2/FAK1 and paxillin (PXN). In addition to  phosphorylating focal adhesion proteins, SRC is also active at the  sites of cell-cell contact adherens junctions and phosphorylates  substrates such as beta-catenin (CTNNB1), delta-catenin (CTNND1),  and plakoglobin (JUP). Another type of cell-cell junction, the gap  junction, is also a target for SRC, which phosphorylates connexin-  43 (GJA1). SRC is implicated in regulation of pre-mRNA-processing  and phosphorylates RNA-binding proteins such as KHDRBS1. Also  plays a role in PDGF-mediated tyrosine phosphorylation of both  STAT1 and STAT3, leading to increased DNA binding activity of  these transcription factors. Involved in the RAS pathway through  phosphorylation of RASA1 and RASGRF1. Plays a role in EGF-mediated  calcium-activated chloride channel activation. Required for  epidermal growth factor receptor (EGFR) internalization through  phosphorylation of clathrin heavy chain (CLTC and CLTCL1) at 'Tyr-  1477'. Involved in beta-arrestin (ARRB1 and ARRB2) desensitization  through phosphorylation and activation of ADRBK1, leading to beta-  arrestin phosphorylation and internalization. Has a critical role  in the stimulation of the CDK20/MAPK3 mitogen-activated protein  kinase cascade by epidermal growth factor. Might be involved not  only in mediating the transduction of mitogenic signals at the  level of the plasma membrane but also in controlling progression  through the cell cycle via interaction with regulatory proteins in  the nucleus. Plays an important role in osteoclastic bone  resorption in conjunction with PTK2B/PYK2. Both the formation of a  SRC-PTK2B/PYK2 complex and SRC kinase activity are necessary for  this function. Recruited to activated integrins by PTK2B/PYK2,  thereby phosphorylating CBL, which in turn induces the activation  and recruitment of phosphatidylinositol 3-kinase to the cell  membrane in a signaling pathway that is critical for osteoclast  function. Promotes energy production in osteoclasts by activating  mitochondrial cytochrome C oxidase. Phosphorylates DDR2 on  tyrosine residues, thereby promoting its subsequent  autophosphorylation. Phosphorylates RUNX3 and COX2 on tyrosine  residues, TNK2 on 'Tyr-284' and CBL on 'Tyr-731'. Enhances  DDX58/RIG-I-elicited antiviral signaling. Phosphorylates PDPK1 at  'Tyr-9', 'Tyr-373' and 'Tyr-376'. (from UniProt P12931)
SRC (ENST00000373558.2) at chr20:37384150-37406050 - Non-receptor protein tyrosine kinase which is activated  following engagement of many different classes of cellular  receptors including immune response receptors, integrins and other  adhesion receptors, receptor protein tyrosine kinases, G protein-  coupled receptors as well as cytokine receptors. Participates in  signaling pathways that control a diverse spectrum of biological  activities including gene transcription, immune response, cell  adhesion, cell cycle progression, apoptosis, migration, and  transformation. Due to functional redundancy between members of  the SRC kinase family, identification of the specific role of each  SRC kinase is very difficult. SRC appears to be one of the primary  kinases activated following engagement of receptors and plays a  role in the activation of other protein tyrosine kinase (PTK)  families. Receptor clustering or dimerization leads to recruitment  of SRC to the receptor complexes where it phosphorylates the  tyrosine residues within the receptor cytoplasmic domains. Plays  an important role in the regulation of cytoskeletal organization  through phosphorylation of specific substrates such as AFAP1.  Phosphorylation of AFAP1 allows the SRC SH2 domain to bind AFAP1  and to localize to actin filaments. Cytoskeletal reorganization is  also controlled through the phosphorylation of cortactin (CTTN).  When cells adhere via focal adhesions to the extracellular matrix,  signals are transmitted by integrins into the cell resulting in  tyrosine phosphorylation of a number of focal adhesion proteins,  including PTK2/FAK1 and paxillin (PXN). In addition to  phosphorylating focal adhesion proteins, SRC is also active at the  sites of cell-cell contact adherens junctions and phosphorylates  substrates such as beta-catenin (CTNNB1), delta-catenin (CTNND1),  and plakoglobin (JUP). Another type of cell-cell junction, the gap  junction, is also a target for SRC, which phosphorylates connexin-  43 (GJA1). SRC is implicated in regulation of pre-mRNA-processing  and phosphorylates RNA-binding proteins such as KHDRBS1. Also  plays a role in PDGF-mediated tyrosine phosphorylation of both  STAT1 and STAT3, leading to increased DNA binding activity of  these transcription factors. Involved in the RAS pathway through  phosphorylation of RASA1 and RASGRF1. Plays a role in EGF-mediated  calcium-activated chloride channel activation. Required for  epidermal growth factor receptor (EGFR) internalization through  phosphorylation of clathrin heavy chain (CLTC and CLTCL1) at 'Tyr-  1477'. Involved in beta-arrestin (ARRB1 and ARRB2) desensitization  through phosphorylation and activation of ADRBK1, leading to beta-  arrestin phosphorylation and internalization. Has a critical role  in the stimulation of the CDK20/MAPK3 mitogen-activated protein  kinase cascade by epidermal growth factor. Might be involved not  only in mediating the transduction of mitogenic signals at the  level of the plasma membrane but also in controlling progression  through the cell cycle via interaction with regulatory proteins in  the nucleus. Plays an important role in osteoclastic bone  resorption in conjunction with PTK2B/PYK2. Both the formation of a  SRC-PTK2B/PYK2 complex and SRC kinase activity are necessary for  this function. Recruited to activated integrins by PTK2B/PYK2,  thereby phosphorylating CBL, which in turn induces the activation  and recruitment of phosphatidylinositol 3-kinase to the cell  membrane in a signaling pathway that is critical for osteoclast  function. Promotes energy production in osteoclasts by activating  mitochondrial cytochrome C oxidase. Phosphorylates DDR2 on  tyrosine residues, thereby promoting its subsequent  autophosphorylation. Phosphorylates RUNX3 and COX2 on tyrosine  residues, TNK2 on 'Tyr-284' and CBL on 'Tyr-731'. Enhances  DDX58/RIG-I-elicited antiviral signaling. Phosphorylates PDPK1 at  'Tyr-9', 'Tyr-373' and 'Tyr-376'. (from UniProt P12931)
SRC (ENST00000358208.8) at chr20:37382604-37405432 - Non-receptor protein tyrosine kinase which is activated  following engagement of many different classes of cellular  receptors including immune response receptors, integrins and other  adhesion receptors, receptor protein tyrosine kinases, G protein-  coupled receptors as well as cytokine receptors. Participates in  signaling pathways that control a diverse spectrum of biological  activities including gene transcription, immune response, cell  adhesion, cell cycle progression, apoptosis, migration, and  transformation. Due to functional redundancy between members of  the SRC kinase family, identification of the specific role of each  SRC kinase is very difficult. SRC appears to be one of the primary  kinases activated following engagement of receptors and plays a  role in the activation of other protein tyrosine kinase (PTK)  families. Receptor clustering or dimerization leads to recruitment  of SRC to the receptor complexes where it phosphorylates the  tyrosine residues within the receptor cytoplasmic domains. Plays  an important role in the regulation of cytoskeletal organization  through phosphorylation of specific substrates such as AFAP1.  Phosphorylation of AFAP1 allows the SRC SH2 domain to bind AFAP1  and to localize to actin filaments. Cytoskeletal reorganization is  also controlled through the phosphorylation of cortactin (CTTN).  When cells adhere via focal adhesions to the extracellular matrix,  signals are transmitted by integrins into the cell resulting in  tyrosine phosphorylation of a number of focal adhesion proteins,  including PTK2/FAK1 and paxillin (PXN). In addition to  phosphorylating focal adhesion proteins, SRC is also active at the  sites of cell-cell contact adherens junctions and phosphorylates  substrates such as beta-catenin (CTNNB1), delta-catenin (CTNND1),  and plakoglobin (JUP). Another type of cell-cell junction, the gap  junction, is also a target for SRC, which phosphorylates connexin-  43 (GJA1). SRC is implicated in regulation of pre-mRNA-processing  and phosphorylates RNA-binding proteins such as KHDRBS1. Also  plays a role in PDGF-mediated tyrosine phosphorylation of both  STAT1 and STAT3, leading to increased DNA binding activity of  these transcription factors. Involved in the RAS pathway through  phosphorylation of RASA1 and RASGRF1. Plays a role in EGF-mediated  calcium-activated chloride channel activation. Required for  epidermal growth factor receptor (EGFR) internalization through  phosphorylation of clathrin heavy chain (CLTC and CLTCL1) at 'Tyr-  1477'. Involved in beta-arrestin (ARRB1 and ARRB2) desensitization  through phosphorylation and activation of ADRBK1, leading to beta-  arrestin phosphorylation and internalization. Has a critical role  in the stimulation of the CDK20/MAPK3 mitogen-activated protein  kinase cascade by epidermal growth factor. Might be involved not  only in mediating the transduction of mitogenic signals at the  level of the plasma membrane but also in controlling progression  through the cell cycle via interaction with regulatory proteins in  the nucleus. Plays an important role in osteoclastic bone  resorption in conjunction with PTK2B/PYK2. Both the formation of a  SRC-PTK2B/PYK2 complex and SRC kinase activity are necessary for  this function. Recruited to activated integrins by PTK2B/PYK2,  thereby phosphorylating CBL, which in turn induces the activation  and recruitment of phosphatidylinositol 3-kinase to the cell  membrane in a signaling pathway that is critical for osteoclast  function. Promotes energy production in osteoclasts by activating  mitochondrial cytochrome C oxidase. Phosphorylates DDR2 on  tyrosine residues, thereby promoting its subsequent  autophosphorylation. Phosphorylates RUNX3 and COX2 on tyrosine  residues, TNK2 on 'Tyr-284' and CBL on 'Tyr-731'. Enhances  DDX58/RIG-I-elicited antiviral signaling. Phosphorylates PDPK1 at  'Tyr-9', 'Tyr-373' and 'Tyr-376'. (from UniProt P12931)
AKT2 (ENST00000311278.10) at chr19:40233841-40265312 - AKT2 is one of 3 closely related serine/threonine-  protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and  which regulate many processes including metabolism, proliferation,  cell survival, growth and angiogenesis. This is mediated through  serine and/or threonine phosphorylation of a range of downstream  substrates. Over 100 substrate candidates have been reported so  far, but for most of them, no isoform specificity has been  reported. AKT is responsible of the regulation of glucose uptake  by mediating insulin-induced translocation of the SLC2A4/GLUT4  glucose transporter to the cell surface. Phosphorylation of PTPN1  at 'Ser-50' negatively modulates its phosphatase activity  preventing dephosphorylation of the insulin receptor and the  attenuation of insulin signaling. Phosphorylation of TBC1D4  triggers the binding of this effector to inhibitory 14-3-3  proteins, which is required for insulin-stimulated glucose  transport. AKT regulates also the storage of glucose in the form  of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at  'Ser-9', resulting in inhibition of its kinase activity.  Phosphorylation of GSK3 isoforms by AKT is also thought to be one  mechanism by which cell proliferation is driven. AKT regulates  also cell survival via the phosphorylation of MAP3K5 (apoptosis  signal-related kinase). Phosphorylation of 'Ser-83' decreases  MAP3K5 kinase activity stimulated by oxidative stress and thereby  prevents apoptosis. AKT mediates insulin-stimulated protein  synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462',  thereby activating mTORC1 signaling and leading to both  phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is  involved in the phosphorylation of members of the FOXO factors  (Forkhead family of transcription factors), leading to binding of  14-3-3 proteins and cytoplasmic localization. In particular, FOXO1  is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and  FOXO4 are phosphorylated on equivalent sites. AKT has an important  role in the regulation of NF-kappa-B-dependent gene transcription  and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-  response element binding protein). The phosphorylation of CREB1  induces the binding of accessory proteins that are necessary for  the transcription of pro-survival genes such as BCL2 and MCL1. AKT  phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby  potentially regulating ACLY activity and fatty acid synthesis.  Activates the 3B isoform of cyclic nucleotide phosphodiesterase  (PDE3B) via phosphorylation of 'Ser-273', resulting in reduced  cyclic AMP levels and inhibition of lipolysis. Phosphorylates  PIKFYVE on 'Ser-318', which results in increased PI(3)P-5  activity. The Rho GTPase-activating protein DLC1 is another  substrate and its phosphorylation is implicated in the regulation  cell proliferation and cell growth. AKT plays a role as key  modulator of the AKT-mTOR signaling pathway controlling the tempo  of the process of newborn neurons integration during adult  neurogenesis, including correct neuron positioning, dendritic  development and synapse formation. Signals downstream of  phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of  various growth factors such as platelet-derived growth factor  (PDGF), epidermal growth factor (EGF), insulin and insulin-like  growth factor I (IGF-I). AKT mediates the antiapoptotic effects of  IGF-I. Essential for the SPATA13-mediated regulation of cell  migration and adhesion assembly and disassembly. May be involved  in the regulation of the placental development. (from UniProt P31751)
AKT1 (ENST00000649815.1) at chr14:104769371-104795555 - AKT1 is one of 3 closely related serine/threonine-  protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and  which regulate many processes including metabolism, proliferation,  cell survival, growth and angiogenesis. This is mediated through  serine and/or threonine phosphorylation of a range of downstream  substrates. Over 100 substrate candidates have been reported so  far, but for most of them, no isoform specificity has been  reported. AKT is responsible of the regulation of glucose uptake  by mediating insulin-induced translocation of the SLC2A4/GLUT4  glucose transporter to the cell surface. Phosphorylation of PTPN1  at 'Ser-50' negatively modulates its phosphatase activity  preventing dephosphorylation of the insulin receptor and the  attenuation of insulin signaling. Phosphorylation of TBC1D4  triggers the binding of this effector to inhibitory 14-3-3  proteins, which is required for insulin-stimulated glucose  transport. AKT regulates also the storage of glucose in the form  of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at  'Ser-9', resulting in inhibition of its kinase activity.  Phosphorylation of GSK3 isoforms by AKT is also thought to be one  mechanism by which cell proliferation is driven. AKT regulates  also cell survival via the phosphorylation of MAP3K5 (apoptosis  signal-related kinase). Phosphorylation of 'Ser-83' decreases  MAP3K5 kinase activity stimulated by oxidative stress and thereby  prevents apoptosis. AKT mediates insulin-stimulated protein  synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462',  thereby activating mTORC1 signaling and leading to both  phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is  involved in the phosphorylation of members of the FOXO factors  (Forkhead family of transcription factors), leading to binding of  14-3-3 proteins and cytoplasmic localization. In particular, FOXO1  is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and  FOXO4 are phosphorylated on equivalent sites. AKT has an important  role in the regulation of NF-kappa-B-dependent gene transcription  and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-  response element binding protein). The phosphorylation of CREB1  induces the binding of accessory proteins that are necessary for  the transcription of pro-survival genes such as BCL2 and MCL1. AKT  phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby  potentially regulating ACLY activity and fatty acid synthesis.  Activates the 3B isoform of cyclic nucleotide phosphodiesterase  (PDE3B) via phosphorylation of 'Ser-273', resulting in reduced  cyclic AMP levels and inhibition of lipolysis. Phosphorylates  PIKFYVE on 'Ser-318', which results in increased PI(3)P-5  activity. The Rho GTPase-activating protein DLC1 is another  substrate and its phosphorylation is implicated in the regulation  cell proliferation and cell growth. AKT plays a role as key  modulator of the AKT-mTOR signaling pathway controlling the tempo  of the process of newborn neurons integration during adult  neurogenesis, including correct neuron positioning, dendritic  development and synapse formation. Signals downstream of  phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of  various growth factors such as platelet-derived growth factor  (PDGF), epidermal growth factor (EGF), insulin and insulin-like  growth factor I (IGF-I). AKT mediates the antiapoptotic effects of  IGF-I. Essential for the SPATA13-mediated regulation of cell  migration and adhesion assembly and disassembly. May be involved  in the regulation of the placental development. Phosphorylates  STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its:  kinase activity, nuclear translocation, autophosphorylation and  ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-  117' and 'Thr-384' leading to inhibition of its: cleavage, kinase  activity, autophosphorylation at Thr-180, binding to RASSF1 and  nuclear translocation. Phosphorylates SRPK2 and enhances its  kinase activity towards SRSF2 and ACIN1 and promotes its nuclear  translocation. Phosphorylates RAF1 at 'Ser-259' and negatively  regulates its activity. Phosphorylation of BAD stimulates its pro-  apoptotic activity. (from UniProt P31749)
AKT1 (ENST00000554848.5) at chr14:104770341-104794191 - AKT1 is one of 3 closely related serine/threonine-  protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and  which regulate many processes including metabolism, proliferation,  cell survival, growth and angiogenesis. This is mediated through  serine and/or threonine phosphorylation of a range of downstream  substrates. Over 100 substrate candidates have been reported so  far, but for most of them, no isoform specificity has been  reported. AKT is responsible of the regulation of glucose uptake  by mediating insulin-induced translocation of the SLC2A4/GLUT4  glucose transporter to the cell surface. Phosphorylation of PTPN1  at 'Ser-50' negatively modulates its phosphatase activity  preventing dephosphorylation of the insulin receptor and the  attenuation of insulin signaling. Phosphorylation of TBC1D4  triggers the binding of this effector to inhibitory 14-3-3  proteins, which is required for insulin-stimulated glucose  transport. AKT regulates also the storage of glucose in the form  of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at  'Ser-9', resulting in inhibition of its kinase activity.  Phosphorylation of GSK3 isoforms by AKT is also thought to be one  mechanism by which cell proliferation is driven. AKT regulates  also cell survival via the phosphorylation of MAP3K5 (apoptosis  signal-related kinase). Phosphorylation of 'Ser-83' decreases  MAP3K5 kinase activity stimulated by oxidative stress and thereby  prevents apoptosis. AKT mediates insulin-stimulated protein  synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462',  thereby activating mTORC1 signaling and leading to both  phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is  involved in the phosphorylation of members of the FOXO factors  (Forkhead family of transcription factors), leading to binding of  14-3-3 proteins and cytoplasmic localization. In particular, FOXO1  is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and  FOXO4 are phosphorylated on equivalent sites. AKT has an important  role in the regulation of NF-kappa-B-dependent gene transcription  and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-  response element binding protein). The phosphorylation of CREB1  induces the binding of accessory proteins that are necessary for  the transcription of pro-survival genes such as BCL2 and MCL1. AKT  phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby  potentially regulating ACLY activity and fatty acid synthesis.  Activates the 3B isoform of cyclic nucleotide phosphodiesterase  (PDE3B) via phosphorylation of 'Ser-273', resulting in reduced  cyclic AMP levels and inhibition of lipolysis. Phosphorylates  PIKFYVE on 'Ser-318', which results in increased PI(3)P-5  activity. The Rho GTPase-activating protein DLC1 is another  substrate and its phosphorylation is implicated in the regulation  cell proliferation and cell growth. AKT plays a role as key  modulator of the AKT-mTOR signaling pathway controlling the tempo  of the process of newborn neurons integration during adult  neurogenesis, including correct neuron positioning, dendritic  development and synapse formation. Signals downstream of  phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of  various growth factors such as platelet-derived growth factor  (PDGF), epidermal growth factor (EGF), insulin and insulin-like  growth factor I (IGF-I). AKT mediates the antiapoptotic effects of  IGF-I. Essential for the SPATA13-mediated regulation of cell  migration and adhesion assembly and disassembly. May be involved  in the regulation of the placental development. Phosphorylates  STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its:  kinase activity, nuclear translocation, autophosphorylation and  ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-  117' and 'Thr-384' leading to inhibition of its: cleavage, kinase  activity, autophosphorylation at Thr-180, binding to RASSF1 and  nuclear translocation. Phosphorylates SRPK2 and enhances its  kinase activity towards SRSF2 and ACIN1 and promotes its nuclear  translocation. Phosphorylates RAF1 at 'Ser-259' and negatively  regulates its activity. Phosphorylation of BAD stimulates its pro-  apoptotic activity. (from UniProt P31749)
AKT1 (ENST00000554581.5) at chr14:104769349-104794124 - AKT1 is one of 3 closely related serine/threonine-  protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and  which regulate many processes including metabolism, proliferation,  cell survival, growth and angiogenesis. This is mediated through  serine and/or threonine phosphorylation of a range of downstream  substrates. Over 100 substrate candidates have been reported so  far, but for most of them, no isoform specificity has been  reported. AKT is responsible of the regulation of glucose uptake  by mediating insulin-induced translocation of the SLC2A4/GLUT4  glucose transporter to the cell surface. Phosphorylation of PTPN1  at 'Ser-50' negatively modulates its phosphatase activity  preventing dephosphorylation of the insulin receptor and the  attenuation of insulin signaling. Phosphorylation of TBC1D4  triggers the binding of this effector to inhibitory 14-3-3  proteins, which is required for insulin-stimulated glucose  transport. AKT regulates also the storage of glucose in the form  of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at  'Ser-9', resulting in inhibition of its kinase activity.  Phosphorylation of GSK3 isoforms by AKT is also thought to be one  mechanism by which cell proliferation is driven. AKT regulates  also cell survival via the phosphorylation of MAP3K5 (apoptosis  signal-related kinase). Phosphorylation of 'Ser-83' decreases  MAP3K5 kinase activity stimulated by oxidative stress and thereby  prevents apoptosis. AKT mediates insulin-stimulated protein  synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462',  thereby activating mTORC1 signaling and leading to both  phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is  involved in the phosphorylation of members of the FOXO factors  (Forkhead family of transcription factors), leading to binding of  14-3-3 proteins and cytoplasmic localization. In particular, FOXO1  is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and  FOXO4 are phosphorylated on equivalent sites. AKT has an important  role in the regulation of NF-kappa-B-dependent gene transcription  and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-  response element binding protein). The phosphorylation of CREB1  induces the binding of accessory proteins that are necessary for  the transcription of pro-survival genes such as BCL2 and MCL1. AKT  phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby  potentially regulating ACLY activity and fatty acid synthesis.  Activates the 3B isoform of cyclic nucleotide phosphodiesterase  (PDE3B) via phosphorylation of 'Ser-273', resulting in reduced  cyclic AMP levels and inhibition of lipolysis. Phosphorylates  PIKFYVE on 'Ser-318', which results in increased PI(3)P-5  activity. The Rho GTPase-activating protein DLC1 is another  substrate and its phosphorylation is implicated in the regulation  cell proliferation and cell growth. AKT plays a role as key  modulator of the AKT-mTOR signaling pathway controlling the tempo  of the process of newborn neurons integration during adult  neurogenesis, including correct neuron positioning, dendritic  development and synapse formation. Signals downstream of  phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of  various growth factors such as platelet-derived growth factor  (PDGF), epidermal growth factor (EGF), insulin and insulin-like  growth factor I (IGF-I). AKT mediates the antiapoptotic effects of  IGF-I. Essential for the SPATA13-mediated regulation of cell  migration and adhesion assembly and disassembly. May be involved  in the regulation of the placental development. Phosphorylates  STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its:  kinase activity, nuclear translocation, autophosphorylation and  ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-  117' and 'Thr-384' leading to inhibition of its: cleavage, kinase  activity, autophosphorylation at Thr-180, binding to RASSF1 and  nuclear translocation. Phosphorylates SRPK2 and enhances its  kinase activity towards SRSF2 and ACIN1 and promotes its nuclear  translocation. Phosphorylates RAF1 at 'Ser-259' and negatively  regulates its activity. Phosphorylation of BAD stimulates its pro-  apoptotic activity. (from UniProt P31749)
AKT1 (ENST00000402615.6) at chr14:104769352-104794528 - AKT1 is one of 3 closely related serine/threonine-  protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and  which regulate many processes including metabolism, proliferation,  cell survival, growth and angiogenesis. This is mediated through  serine and/or threonine phosphorylation of a range of downstream  substrates. Over 100 substrate candidates have been reported so  far, but for most of them, no isoform specificity has been  reported. AKT is responsible of the regulation of glucose uptake  by mediating insulin-induced translocation of the SLC2A4/GLUT4  glucose transporter to the cell surface. Phosphorylation of PTPN1  at 'Ser-50' negatively modulates its phosphatase activity  preventing dephosphorylation of the insulin receptor and the  attenuation of insulin signaling. Phosphorylation of TBC1D4  triggers the binding of this effector to inhibitory 14-3-3  proteins, which is required for insulin-stimulated glucose  transport. AKT regulates also the storage of glucose in the form  of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at  'Ser-9', resulting in inhibition of its kinase activity.  Phosphorylation of GSK3 isoforms by AKT is also thought to be one  mechanism by which cell proliferation is driven. AKT regulates  also cell survival via the phosphorylation of MAP3K5 (apoptosis  signal-related kinase). Phosphorylation of 'Ser-83' decreases  MAP3K5 kinase activity stimulated by oxidative stress and thereby  prevents apoptosis. AKT mediates insulin-stimulated protein  synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462',  thereby activating mTORC1 signaling and leading to both  phosphorylation of 4E-BP1 and in activation of RPS6KB1. AKT is  involved in the phosphorylation of members of the FOXO factors  (Forkhead family of transcription factors), leading to binding of  14-3-3 proteins and cytoplasmic localization. In particular, FOXO1  is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319'. FOXO3 and  FOXO4 are phosphorylated on equivalent sites. AKT has an important  role in the regulation of NF-kappa-B-dependent gene transcription  and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-  response element binding protein). The phosphorylation of CREB1  induces the binding of accessory proteins that are necessary for  the transcription of pro-survival genes such as BCL2 and MCL1. AKT  phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby  potentially regulating ACLY activity and fatty acid synthesis.  Activates the 3B isoform of cyclic nucleotide phosphodiesterase  (PDE3B) via phosphorylation of 'Ser-273', resulting in reduced  cyclic AMP levels and inhibition of lipolysis. Phosphorylates  PIKFYVE on 'Ser-318', which results in increased PI(3)P-5  activity. The Rho GTPase-activating protein DLC1 is another  substrate and its phosphorylation is implicated in the regulation  cell proliferation and cell growth. AKT plays a role as key  modulator of the AKT-mTOR signaling pathway controlling the tempo  of the process of newborn neurons integration during adult  neurogenesis, including correct neuron positioning, dendritic  development and synapse formation. Signals downstream of  phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of  various growth factors such as platelet-derived growth factor  (PDGF), epidermal growth factor (EGF), insulin and insulin-like  growth factor I (IGF-I). AKT mediates the antiapoptotic effects of  IGF-I. Essential for the SPATA13-mediated regulation of cell  migration and adhesion assembly and disassembly. May be involved  in the regulation of the placental development. Phosphorylates  STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its:  kinase activity, nuclear translocation, autophosphorylation and  ability to phosphorylate FOXO3. Phosphorylates STK3/MST2 at 'Thr-  117' and 'Thr-384' leading to inhibition of its: cleavage, kinase  activity, autophosphorylation at Thr-180, binding to RASSF1 and  nuclear translocation. Phosphorylates SRPK2 and enhances its  kinase activity towards SRSF2 and ACIN1 and promotes its nuclear  translocation. Phosphorylates RAF1 at 'Ser-259' and negatively  regulates its activity. Phosphorylation of BAD stimulates its pro-  apoptotic activity. (from UniProt P31749)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_006218.3 at chr3:179148523-179240093

NCBI RefSeq genes, predicted subset (XM_* or XR_*)

XM_006713658.4 at chr3:179148114-179235137
XM_011512894.2 at chr3:179149530-179235137

NCBI RefSeq and Ensembl transcripts from the MANE Project (v0.6)

PIK3CA at chr3:179148357-179240093

RefSeq Genes

PIK3CA at chr3:179148357-179240093 - (NM_006218) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Non-Human RefSeq Genes

PIK3CA at chr3:179148579-179234654 - (NM_001260668) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
pik3ca at chr3:179198826-179234346 - (NM_001126500) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
PIK3CA at chr3:179198825-179234381 - (NM_001004410) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Pik3ca at chr3:179198826-179237525 - (NM_133399) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
PIK3CA at chr3:179198826-179234364 - (NM_174574) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Pik3ca at chr3:179198776-179237915 - (NM_008839) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

PIK3CA at chr3:179148357-179240093
PIK3CA at chr3:179148574-179235098

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148357-179240093
PIK3CA at chr3:179148574-179235098
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179148574-179235098

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179148574-179235098
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179148574-179235098

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179148574-179235098
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

PIK3CA at chr3:179148523-179240093

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

PIK3CA at chr3:179148523-179240093

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

PIK3CA at chr3:179148523-179240093

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

PIK3CA at chr3:179148523-179240093

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

PIK3CA at chr3:179148523-179240093

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

PIK3CA at chr3:179148523-179240093

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

PIK3CA at chr3:179148523-179240093

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

PIK3CA at chr3:179148114-179198888
PIK3CA at chr3:179148523-179240093
PIK3CA at chr3:179149527-179199179
PIK3CA at chr3:179219551-179226017

International Knockout Mouse Consortium Genes Mapped to Human Genome

Pik3ca_28086 at chr3:179148523-179234712
Pik3ca_49296 at chr3:179148523-179234712
Pik3ca_69628 at chr3:179148523-179234712
Pik3ca_VG18469 at chr3:179148523-179234712

Human Aligned mRNA Search Results

AB210020 - Homo sapiens mRNA for PIK3CA variant protein, clone: fk03260.
BC113601 - Homo sapiens phosphoinositide-3-kinase, catalytic, alpha polypeptide, mRNA (cDNA clone MGC:142161 IMAGE:8322653), complete cds.
BC113603 - Homo sapiens phosphoinositide-3-kinase, catalytic, alpha polypeptide, mRNA (cDNA clone MGC:142163 IMAGE:8322655), complete cds.
HM437241 - Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform variant (PIK3CA) mRNA, partial cds.
LN626316 - Homo sapiens miRNA for PIK3CA-mir1-3p1.
LN626315 - Homo sapiens miRNA for PIK3CA-mir1-3p.

Non-Human Aligned mRNA Search Results

KF921496 - Tupaia chinensis PIK3CA mRNA, complete cds.
BC089038 - Mus musculus phosphatidylinositol 3-kinase, catalytic, alpha polypeptide, mRNA (cDNA clone MGC:115793 IMAGE:30692343), complete cds.
BC130228 - Mus musculus phosphatidylinositol 3-kinase, catalytic, alpha polypeptide, mRNA (cDNA clone MGC:161268 IMAGE:40141870), complete cds.
HQ890081 - Equus caballus clone 06_f01 phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha isoform-like protein (PIK3CA) mRNA, partial cds.
AB479386 - Mesocricetus auratus PIK3CA mRNA for phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, partial cds.
DQ073082 - Cricetulus griseus phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) mRNA, partial cds.
AY335705 - Synthetic construct Homo sapiens phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA) mRNA, partial cds.
JU335001 - TSA: Macaca mulatta Mamu_516751 mRNA sequence.
JU476009 - TSA: Macaca mulatta Mamu_361555 mRNA sequence.

GeneReviews

PIK3CA-Related Segmental Overgrowth at chr3:179148357-179240093 - (PIK3CA)