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Gencode Genes

PELI1 (ENST00000358912.5) at chr2:64092652-64144420 - <b>PELI1</b> ENST00000358912.5 Homo sapiens pellino E3 ubiquitin protein ligase 1 
IRAK1 (ENST00000369980.8) at chrX:154010507-154019902 -  ... autophosphorylation and kinase activation Phosphorylates E3 ubiquitin ligases Pellino proteins <b>PELI1</b> PELI2 and PELI3 to promote pellino-mediated polyubiquitination of IRAK1 
IRAK4 (ENST00000613694.5) at chr12:43758951-43789541 -  ... intensive autophosphorylation of IRAK1 Phosphorylates E3 ubiquitin ligases Pellino proteins <b>PELI1</b> PELI2 and PELI3 to promote pellino-mediated polyubiquitination of IRAK1 
IRAK2 (ENST00000256458.5) at chr3:10164919-10243745 -  ... which dissociates from the IL-1 receptor following the binding of <b>PELI1</b> P10398 ARAF NbExp 2 IntAct EBI-447733 EBI-365961 P51617 IRAK1 
TRAF6 (ENST00000526995.6) at chr11:36483769-36510272 -  ... ternary complex with SQSTM1 and PRKCZ By similarity Interacts with <b>PELI1</b> PELI2 and PELI3 Binds UBE2V1 Interacts with MAVS IPS1 
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