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Gencode Genes

MYC (ENST00000621592.8) at chr8:127736231-127742951 - <b>MYC</b> ENST00000621592.8 Homo sapiens MYC proto-oncogene bHLH transcription factor MYC 
FUBP1 (ENST00000370768.7) at chr1:77944055-77979072 - FUBP1 ENST00000370768.7 Regulates <b>MYC</b> expression by binding to a single-stranded far-upstream element FUSE 
MINCR (ENST00000517411.4) at chr8:143280152-143281705 - MINCR ENST00000517411.4 Homo sapiens <b>MYC-induced</b> long non-coding RNA MINCR transcript variant 1 long non-coding 
MAX (ENST00000358664.9) at chr14:65075127-65102517 - MAX ENST00000358664.9 Homo sapiens <b>MYC</b> associated factor X MAX transcript variant 1 mRNA from 
MAZ (ENST00000322945.11) at chr16:29806529-29811164 - MAZ ENST00000322945.11 Homo sapiens <b>MYC</b> associated zinc finger protein MAZ transcript variant 5 non-coding 
ZBTB14 (ENST00000651870.1) at chr18:5289022-5295726 -  ... O00403 O43829 Q2TB80 ZF161_HUMAN ZFP161 ZNF478 uc287hzl.1 Transcriptional repressor of <b>MYC</b> and thymidine kinase promoters By similarity Transcriptional activator of 
MNT (ENST00000174618.5) at chr17:2384073-2401060 -  ... NM_020310 Q1ED38 Q99583 ROX uc002fur.1 uc002fur.2 uc002fur.3 uc002fur.4 uc002fur.5 The <b>Myc</b> Max Mad network comprises a group of transcription factors 
MGA (ENST00000566586.6) at chr15:41660397-41773081 -  ... Binds to 5 AATTTCACACCTAGGTGTGAAATT-3 core sequence and seems to regulate <b>MYC-MAX</b> target genes Suppresses transcriptional activation by MYC and inhibits 
BCL7A (ENST00000261822.5) at chr12:122021884-122062044 -  ... uc001ubp.2 uc001ubp.3 uc001ubp.4 uc001ubp.5 This gene is directly involved with <b>Myc</b> and IgH in a three-way gene translocation in a 
MXD1 (ENST00000264444.7) at chr2:69915109-69942945 -  ... uc002sfy.3 uc002sfy.4 uc002sfy.5 This gene encodes a member of the <b>MYC</b> MAX MAD network of basic helix-loop-helix leucine zipper transcription 
MXD3 (ENST00000439742.7) at chr5:177307210-177311898 -  ... uc003mgb.2 uc003mgb.3 uc003mgb.4 This gene encodes a member of the <b>Myc</b> superfamily of basic helix-loop-helix leucine zipper transcriptional regulators The 
RIOX2 (ENST00000394198.7) at chr3:97941818-97972431 -  ... Q8IUF8 Q96C17 Q96KB0 uc003dsb.1 uc003dsb.2 uc003dsb.3 MINA is a c-Myc <b>MYC</b> MIM 190080 target gene that may play a role 
CIP2A (ENST00000295746.13) at chr3:108549864-108589438 -  ... uc003dxb.3 uc003dxb.4 uc003dxb.5 uc003dxb.6 Oncoprotein that inhibits PP2A and stabilizes <b>MYC</b> in human malignancies Promotes anchorage-independent cell growth and tumor 
NMI (ENST00000243346.10) at chr2:151270470-151289668 -  ... interacts with NMYC and CMYC two members of the oncogene <b>Myc</b> family and other transcription factors containing a Zip HLH 
NOP16 (ENST00000614830.5) at chr5:176383946-176388598 -  ... nucleolus Expression of this gene is induced by estrogens and <b>Myc</b> protein and is a marker of poor patient survival 
SIN3B (ENST00000248054.10) at chr19:16829398-16880349 -  ... Acts as a transcriptional repressor Interacts with MXI1 to repress <b>MYC</b> responsive genes and antagonize MYC oncogenic activities Interacts with 
MLXIPL (ENST00000313375.8) at chr7:73593202-73624522 -  ... encodes a basic helix-loop-helix leucine zipper transcription factor of the <b>Myc</b> Max Mad superfamily This protein forms a heterodimeric complex 
STAMBP (ENST00000394070.7) at chr2:73828961-73867168 -  ... contains an SH3 domain that is required for induction of <b>MYC</b> and cell growth The protein encoded by this gene 
PIM3 (ENST00000360612.5) at chr22:49960772-49964072 -  ... overexpressed in hematological and epithelial tumors and is associated with <b>MYC</b> coexpression It plays a role in the regulation of 
TCEAL7 (ENST00000332431.5) at chrX:103330239-103332326 -  ... its target gene promoters Associates with cyclin D1 promoter containing <b>Myc</b> E-box sequence and transcriptionally represses cyclin D1 expression Regulates 
PCGEM1 (ENST00000454040.5) at chr2:192749845-192776899 -  ... of apoptosis and may promote activity of androgen receptor and <b>Myc</b> provided by RefSeq Dec 2017 Sequence Note The RefSeq 
BIN1 (ENST00000316724.10) at chr2:127048032-127107154 -  ... adaptor protein one of which was initially identified as a <b>MYC-interacting</b> protein with features of a tumor suppressor Isoforms that 
MXD4 (ENST00000337190.7) at chr4:2247432-2262109 -  ... repression complex The MAD proteins compete for MAX binding with <b>MYC</b> which heterodimerizes with MAX forming a transcriptional activation complex 
TRPC4AP (ENST00000252015.3) at chr20:35002404-35092807 -  ... TRUSS complex specifically mediates the polyubiquitination and subsequent degradation of <b>MYC</b> Also participates in the activation of NFKB1 in response 
YAF2 (ENST00000534854.7) at chr12:42157104-42238248 -  ... protein Yy1 and also interacts with other transcriptional regulators including <b>Myc</b> and Polycomb This protein can promote proteolysis of Yy1 
USP22 (ENST00000261497.9) at chr17:20999596-21043011 -  ... coactivator Recruited to specific gene promoters by activators such as <b>MYC</b> where it is required for transcription Required for nuclear 
CDCA7 (ENST00000306721.8) at chr2:173354872-173368997 -  ... the transformation of lymphoblastoid cells and it complements a transformation-defective <b>Myc</b> Box II mutant suggesting its involvement in c-Myc-mediated cell 
DENND4A (ENST00000443035.8) at chr15:65659123-65792293 -  ... may be involved in regulating the v-myc avian myelocytomatosis viral <b>MYC</b> oncogene Alternate splicing results in multiple transcript variants A 
USP36 (ENST00000449938.7) at chr17:78795652-78840814 -  ... deubiquitinate and stabilize the transcription factor c-Myc also known as <b>MYC</b> an important oncoprotein known to be upregulated in most 
MXI1 (ENST00000332674.9) at chr10:110207605-110287365 -  ... this gene is a transcriptional repressor thought to negatively regulate <b>MYC</b> function and is therefore a potential tumor suppressor This 
NHLH1 (ENST00000302101.6) at chr1:160367071-160372846 -  ... tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors <b>MYC</b> MIM 190080 LYL1 MIM 151440 E2A MIM 147141 and 
CDCA7L (ENST00000406877.8) at chr7:21900899-21945899 -  ... important oncogenic role in mediating the full transforming effect of <b>MYC</b> in medulloblastoma cells Involved in apoptotic signaling pathways May 
EHMT1 (ENST00000460843.6) at chr9:137619005-137836127 -  ... repression This protein may be involved in the silencing of <b>MYC</b> and E2F-responsive genes and therefore could play a role 
RNF17 (ENST00000255324.10) at chr13:24764169-24879921 -  ... Seems to be involved in regulation of transcriptional activity of <b>MYC</b> In vitro inhibits DNA-binding activity of Mad MAX heterodimers 
ATXN7L3 (ENST00000587097.6) at chr17:44191805-44199884 -  ... is recruited to specific gene promoters by activators such as <b>MYC</b> where it is required for transcription Required for nuclear 
CAPRIN1 (ENST00000341394.9) at chr11:34051731-34102610 -  ... G3BP1 in cytoplasmic RNA granules Binds directly and selectively to <b>MYC</b> and CCND2 RNAs In neuronal cells directly binds to 
PUF60 (ENST00000526683.6) at chr8:143816344-143829315 -  ... DNA element FUSE and FUSE-binding protein at the myelocytomatosis oncogene <b>MYC</b> promoter This complex represses MYC transcription through the core-TFIIH 
TFAP2E (ENST00000373235.4) at chr1:35573314-35595328 -  ... number of genes including MCAM MUC18 C EBP alpha and <b>MYC</b> AP-2-epsilon may play a role in the development of 
ENY2 (ENST00000521688.6) at chr8:109334347-109345954 -  ... is recruited to specific gene promoters by activators such as <b>MYC</b> where it is required for transcription Required for nuclear 
SIN3A (ENST00000394947.8) at chr15:75369379-75451690 -  ... transcriptional repressor Corepressor for REST Interacts with MXI1 to repress <b>MYC</b> responsive genes and antagonize MYC oncogenic activities Also interacts 
TFAP2D (ENST00000008391.4) at chr6:50713526-50773033 -  ... number of genes including MCAM MUC18 C EBP alpha and <b>MYC</b> By similarity Binds DNA as a dimer Can form 
STK38 (ENST00000229812.8) at chr6:36493892-36547479 -  ... to regulate the protein stability and transcriptional activity of the <b>MYC</b> oncogene Alternative splicing results in multiple transcript variants provided 
EP400 (ENST00000389561.7) at chr12:131949942-132080460 -  ... transcription May be required for transcriptional activation of E2F1 and <b>MYC</b> target genes during cellular proliferation The NuA4 complex ATPase 
MAP3K12 (ENST00000547488.6) at chr12:53479669-53499458 -  ... factors such as cAMP responsive element binding protein CREB and <b>MYC</b> and thus may play a regulatory role in PKA 
BOP1 (ENST00000569669.6) at chr8:144262045-144291438 -  ... NbExp 3 IntAct EBI-1050828 EBI-2490660 Nucleus nucleolus Nucleus nucleoplasm By <b>MYC</b> Belongs to the WD repeat BOP1 ERB1 family Contains 
DDX18 (ENST00000263239.7) at chr2:117814691-117832377 -  ... encodes a DEAD box protein and it is activated by <b>Myc</b> protein provided by RefSeq Jul 2008 Publication Note This 
AIMP2 (ENST00000223029.8) at chr7:6009272-6023834 -  ... Mediates ubiquitination and degradation of FUBP1 a transcriptional activator of <b>MYC</b> leading to MYC down regulation which is required for 
PARP10 (ENST00000313028.12) at chr8:143977158-143986460 -  ... ADP-D-ribosyl n acceptor nicotinamide ADP-D-ribosyl n 1 acceptor Interacts with <b>MYC</b> Nucleus nucleolus Cytoplasm Note Shuttles between the nuclear and 
CASP5 (ENST00000260315.8) at chr11:104994243-105023168 -  ... induces apoptosis in fibroblasts Max a central component of the <b>Myc</b> Max Mad transcription regulation network important for cell growth 
EFTUD2 (ENST00000426333.7) at chr17:44849948-44899445 -  ... the spliceosome C complex Interacts with ERBB4 and PRPF8 P01106 <b>MYC</b> NbExp 5 IntAct EBI-357897 EBI-447544 Q6P2Q9 PRPF8 NbExp 2 
HNRNPU (ENST00000640218.2) at chr1:244850297-244864543 -  ... RefSeq Jun 2017 Component of the CRD-mediated complex that promotes <b>MYC</b> mRNA stabilization Binds to pre-mRNA Has high affinity for 
CTCFL (ENST00000243914.8) at chr20:57497166-57525140 -  ... promoter Required for dimethylation of H3 lysine 4 H3K4me2 of <b>MYC</b> and BRCA1 promoters from UniProt Q8NI51 A1L4C6 BORIS CTCFL_HUMAN 
RIOX1 (ENST00000304061.8) at chr14:73490933-73493394 -  ... the replication or remodeling of certain heterochromatic region Participates in <b>MYC-induced</b> transcriptional activation Protein N 6 N 6 dimethyl-L-lysine 2 
FOXO3 (ENST00000406360.2) at chr6:108560917-108684774 -  ... 5 AG TAAA TC A-3 Participates in post-transcriptional regulation of <b>MYC</b> following phosphorylation by MAPKAPK5 promotes induction of miR-34b and 
IGF2BP1 (ENST00000290341.8) at chr17:48997385-49056145 -  ... and translation Component of the CRD mediated complex that promotes <b>MYC</b> mRNA stabilization Regulates mRNA stability during the integrated cellular 
CCNY (ENST00000374704.8) at chr10:35336509-35572667 -  ... Isoform 3 might play a role in the activation of <b>MYC-mediated</b> transcription Interacts with CDK14 CDK16 and LRP6 Cell membrane 
NSUN2 (ENST00000264670.11) at chr5:6599239-6633044 -  ... tRNAs at positions 48 or 49 May act downstream of <b>Myc</b> to regulate epidermal cell growth and proliferation Required for 
PIM2 (ENST00000376509.4) at chrX:48913182-48919024 -  ... cell proliferation Exerts its oncogenic activity through the regulation of <b>MYC</b> transcriptional activity the regulation of cell cycle progression the 
RNF213 (ENST00000582970.6) at chr17:80260852-80398794 -  ... 8 17 q24 q25 translocation has been identified with the <b>MYC</b> gene on chromosome 8 Alternative splicing results in multiple 
STAM (ENST00000377524.8) at chr10:17644151-17716824 -  ... plays a role in signaling leading to DNA synthesis and <b>MYC</b> induction May also play a role in T-cell development 
TCF7L2 (ENST00000355995.9) at chr10:112950247-113167678 -  ... 0000332 Evidence-Data-END Participates in the Wnt signaling pathway and modulates <b>MYC</b> expression by binding to its promoter in a sequence-specific 
CCAR1 (ENST00000265872.11) at chr10:68721239-68792377 -  ... mediated altered expression of multiple cell cycle regulatory genes including <b>MYC</b> CCNB1 and CDKN1A Plays a role in cell cycle 
CDK2 (ENST00000266970.9) at chr12:55966830-55972789 -  ... mitosis Phosphorylates CTNNB1 USP37 p53 TP53 NPM1 CDK7 RB1 BRCA2 <b>MYC</b> NPAT EZH2 Interacts with cyclins A B1 B3 D 
RBMS1 (ENST00000348849.8) at chr2:160272151-160493807 -  ... binding protein that interacts with the region upstream of the <b>MYC</b> gene Binds specifically to the DNA sequence motif 5 
MAD1L1 (ENST00000265854.12) at chr7:1815795-2232945 -  ... TERT promoter and represses telomerase expression possibly by interfering with <b>MYC</b> binding Homodimer Heterodimerizes with MAD2L1 in order to form 
DHX9 (ENST00000367549.4) at chr1:182839347-182887982 -  ... transcriptional activator Component of the CRD mediated complex that promotes <b>MYC</b> mRNA stability Involved with LARP6 in the stabilization of 
PFDN5 (ENST00000334478.9) at chr12:53295542-53299450 -  ... competing pathways for nonnative proteins Represses the transcriptional activity of <b>MYC</b> Heterohexamer of two PFD-alpha type and four PFD-beta type 
SYNCRIP (ENST00000369622.8) at chr6:85613976-85642886 -  ... processing mechanisms Component of the CRD mediated complex that promotes <b>MYC</b> mRNA stability Isoform 1 isoform 2 and isoform 3 
SPAG9 (ENST00000262013.12) at chr17:50962174-51120868 -  ... interaction Homooligomer Interacts with MAX MAPK8 MAPK9 MAPK10 MAPK14 MAP3K3 <b>MYC</b> KNS2 and MAP2K4 Interaction with KNS2 is important in 
NCOA5 (ENST00000290231.11) at chr20:46060991-46089962 -  ... nuclear steroid receptors ER as well as the corepression of <b>MYC</b> in response to 17-beta-estradiol E2 Binds HTATIP2 TIP30 Interacts 
PIM1 (ENST00000373509.6) at chr6:37170152-37175428 -  ... in tumorigenesis Exerts its oncogenic activity through the regulation of <b>MYC</b> transcriptional activity the regulation of cell cycle progression and 
MRGBP (ENST00000370487.5) at chr20:62796473-62801729 -  ... GAS41 VPS72 YL1 and MEAF6 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein MRGBP may interact directly 
FRAT1 (ENST00000371021.5) at chr10:97319271-97321915 -  ... a role in tumor progression and collaborate with PIM1 and <b>MYC</b> in lymphomagenesis Binds DVL1 Binds GSK-3 and prevent GSK-3-dependent 
FBXW8 (ENST00000652555.1) at chr12:116910950-117031148 -  ... SKP1 FBXW8 and GLMN isoform 1 Interacts with CUL7 P01106 <b>MYC</b> NbExp 3 IntAct EBI-914770 EBI-447544 Event Alternative splicing Named 
UBTF (ENST00000436088.6) at chr17:44205040-44219675 -  ... to IRS1 and PIK3CA By similarity Interacts with DHX33 P01106 <b>MYC</b> NbExp 2 IntAct EBI-396235 EBI-447544 Nucleus nucleolus By similarity 
ING4 (ENST00000341550.9) at chr12:6650301-6663119 -  ... loss of contact inhibition elicited by activated oncogenes such as <b>MYC</b> Represses hypoxia inducible factor s HIF activity by interacting 
NDUFAF2 (ENST00000296597.10) at chr5:60945205-61153026 -  ... expressed in heart skeletal muscle liver and in fibroblasts By <b>MYC</b> Direct transcriptional target of MYC Defects in NDUFAF2 are 
KDM5B (ENST00000367265.9) at chr1:202724495-202808421 -  ... 2 ion per subunit By similarity Interacts with FOXG1B PAX9 <b>MYC</b> MYCN and RB1 Interacts with HDAC1 HDAC4 HDAC5 and 
SGF29 (ENST00000317058.8) at chr16:28553920-28591790 -  ... required to recruit complexes to H3K4me May be involved in <b>MYC-mediated</b> oncogenic transformation Interacts with TADA3L GCN5L2 SUPT3H and MYC 
CUL1 (ENST00000325222.9) at chr7:148698903-148801110 -  ... of ORC1 CDT1 RBL2 ELF4 CDKN1A RAG2 FOXO1A and probably <b>MYC</b> and TAL1 SCF FBXW7 directs ubiquitination of cyclin E 
GFI1B (ENST00000372122.4) at chr9:132978694-132991687 -  ... cell lines markedly increase apoptosis rate Inhibits down regulation of <b>MYC</b> and MYB as well as the cyclin-dependent kinase inhibitor 
ELAVL1 (ENST00000407627.7) at chr19:7958573-8005641 -  ... on single protein-coding transcript RefSeq-Attributes-END Involved in 3 UTR ARE-mediated <b>MYC</b> stabilization Binds avidly to the AU-rich element in FOS 
EPCAM (ENST00000263735.9) at chr2:47369311-47387020 -  ... stem cells proliferation and differentiation Up-regulates the expression of FABP5 <b>MYC</b> and cyclins A and E Monomer Interacts with phosphorylated 
PURA (ENST00000331327.5) at chr5:140114109-140125619 -  ... single strand of the PUR element located upstream of the <b>MYC</b> gene May play a role in the initiation of 
CTCF (ENST00000264010.10) at chr16:67562526-67639177 -  ... silencers Acts as transcriptional repressor binding to promoters of vertebrate <b>MYC</b> gene and BAG1 gene Also binds to the PLK 
ATAD2 (ENST00000287394.10) at chr8:123319850-123396447 -  ... of a subset of estradiol target genes such as CCND1 <b>MYC</b> and E2F1 May play a role in the recruitment 
PURB (ENST00000395699.5) at chr7:44876299-44885530 -  ... single strand of the PUR element located upstream of the <b>MYC</b> gene Plays a role in the control of vascular 
ENO1 (ENST00000234590.10) at chr1:8861000-8878686 -  ... leukocytes and neurons Stimulates immunoglobulin production MBP1 binds to the <b>myc</b> promoter and acts as a transcriptional repressor May be 
CCAR2 (ENST00000308511.9) at chr8:22604757-22620471 -  ... with SUV39H1 this interaction abolishes the interaction with SIRT1 P01106 <b>MYC</b> NbExp 8 IntAct EBI-355410 EBI-447544 Q9Q2G4 ORF xeno NbExp 
TFAP2C (ENST00000201031.3) at chr20:56629306-56639283 -  ... number of genes including MCAM MUC18 C EBP alpha and <b>MYC</b> Binds DNA as a dimer Can form homodimers or 
MORF4L2 (ENST00000441076.7) at chrX:103675498-103686699 -  ... YEATS4 GAS41 and VPS72 YL1 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein MORF4L1 may also participate 
BCAT1 (ENST00000261192.12) at chr12:24810024-24949101 -  ... During embryogenesis expressed in the brain and kidney Overexpressed in <b>MYC-induced</b> tumors such as Burkitt s lymphoma Belongs to the 
STAM2 (ENST00000263904.5) at chr2:152116801-152175763 -  ... plays a role in signaling leading to DNA synthesis and <b>MYC</b> induction May also play a role in T-cell development 
BRD3 (ENST00000303407.12) at chr9:134030305-134068026 -  ... of histone H2A H2B H3 and H4 in vitro P01106 <b>MYC</b> NbExp 3 IntAct EBI-1383460 EBI-447544 Nucleus Probable Note Detected 
CEP57 (ENST00000325542.10) at chr11:95790498-95832693 -  ... not interact with FGF1 or FGF2 isoform 24 kDa P01106 <b>MYC</b> NbExp 3 IntAct EBI-308614 EBI-447544 Nucleus By similarity Cytoplasm 
FBXW7 (ENST00000281708.10) at chr4:152320544-152536092 -  ... to phosphorylated target proteins Involved in the degradation of cyclin-E <b>MYC</b> NOTCH1 released notch intracellular domain NICD and probably PSEN1 
SNIP1 (ENST00000296215.8) at chr1:37534449-37554293 -  ... Binds the SMAD1 OAZ1 PSMB4 complex Interacts with DROSHA P01106 <b>MYC</b> NbExp 9 IntAct EBI-749336 EBI-447544 Nucleus Ubiquitous with highest 
CHD4 (ENST00000544040.7) at chr12:6570082-6607379 -  ... with ZGPAT the interaction is direct Interacts with PCNT P01106 <b>MYC</b> NbExp 2 IntAct EBI-372916 EBI-447544 Nucleus Cytoplasm cytoskeleton centrosome 
LEF1 (ENST00000265165.6) at chr4:108047548-108168932 -  ... cell migration of pancreatic cancer cells Isoform 1 transcriptionally activates <b>MYC</b> and CCND1 expression and enhances proliferation of pancreatic tumor 
TFAP2B (ENST00000393655.4) at chr6:50818871-50847619 -  ... number of genes including MCAM MUC18 C EBP alpha and <b>MYC</b> AP-2-beta appears to be required for normal face and 
TAF1C (ENST00000566732.6) at chr16:84177855-84187057 -  ... TBP with the transcription factor IID TFIID subunits Interacts with <b>MYC</b> and RRN3 Interacts with p53 TP53 the interaction prevents 
MAPKAPK5 (ENST00000550735.7) at chr12:111842228-111902222 -  ... and phosphorylating p53 TP53 Involved in post transcriptional regulation of <b>MYC</b> by mediating phosphorylation of FOXO3 phosphorylation of FOXO3 leads 
PRKDC (ENST00000314191.7) at chr8:47773111-47960136 -  ... PARP1 POU2F1 DHX9 SRF XRCC1 XRCC1 XRCC4 XRCC5 XRCC6 WRN <b>MYC</b> and RFA2 Can phosphorylate C1D not only in the 
MORF4L1 (ENST00000426013.7) at chr15:78872890-78898139 -  ... GAS41 VPS72 YL1 and MEAF6 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein MORF4L1 may also participate 
LIN28B (ENST00000345080.5) at chr6:104957107-105083332 -  ... loop leading to their terminal uridylation and subsequent degradation Mediates <b>MYC-mediated</b> let-7 repression Isoform 1 when overexpressed stimulates growth of 
ZBTB17 (ENST00000375743.9) at chr1:15941869-15976101 -  ... and inhibiting TRAF2 E3 ligase activity By similarity Interacts with <b>MYC</b> via the C-terminal helix-loop-helix motif the interaction inhibits ZBTB17 
ATAD3B (ENST00000673477.1) at chr1:1471765-1497848 -  ... proliferating embryonic stem cells and down-regulated during differentiation Up-regulated by <b>MYC</b> Belongs to the AAA ATPase family Sequence BAA86587.1 Type 
YEATS4 (ENST00000247843.7) at chr12:69359743-69390870 -  ... GAS41 VPS72 YL1 and MEAF6 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein Component of a NuA4-related 
BRD8 (ENST00000254900.10) at chr5:138139770-138178630 -  ... GAS41 VPS72 YL1 and MEAF6 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein Component of a NuA4-related 
SKP2 (ENST00000274255.11) at chr5:36152111-36184319 -  ... ORC1 CDT1 RBL2 MLL CDK9 RAG2 FOXO1 UBP43 and probably <b>MYC</b> TOB1 and TAL1 Degradation of TAL1 also requires STUB1 
WDR12 (ENST00000261015.5) at chr2:202874261-202911673 -  ... NbExp 3 IntAct EBI-2490660 EBI-1050828 Nucleus nucleolus Nucleus nucleoplasm By <b>MYC</b> Belongs to the WD repeat WDR12 YTM1 family Contains 
RUVBL1 (ENST00000322623.10) at chr3:128080810-128123812 -  ... DNA repair Plays an essential role in oncogenic transformation by <b>MYC</b> and also modulates transcriptional activation by the LEF1 TCF1-CTNNB1 
PES1 (ENST00000354694.12) at chr22:30576625-30591910 -  ... are abnormally elevated in malignant tumors of astrocytic origin By <b>MYC</b> Sumoylated Belongs to the pescadillo family Contains 1 BRCT 
CSNK2A1 (ENST00000217244.9) at chr20:472498-543790 -  ... NF-kappa-B STAT1 CREB1 IRF1 IRF2 ATF1 SRF MAX JUN FOS <b>MYC</b> and MYB Phosphorylates Hsp90 and its co-chaperones FKBP4 and 
CDKN2A (ENST00000579755.2) at chr9:21967752-21994392 -  ... BCL6 and down-regulates BCL6-induced transcriptional repression Binds to E2F1 and <b>MYC</b> and blocks their transcriptional activator activity but has no 
KLF4 (ENST00000374672.5) at chr9:107484852-107489769 -  ... number of yeast and animal transcription factors POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
ING3 (ENST00000315870.10) at chr7:120950777-120977216 -  ... GAS41 VPS72 YL1 and MEAF6 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein HTATTIP TIP60 EPC1 and 
YBX1 (ENST00000321358.12) at chr1:42682418-42703805 -  ... in DNA repair Component of the CRD-mediated complex that promotes <b>MYC</b> mRNA stability Binds preferentially to the 5 CU CUGCG-3 
KDM5A (ENST00000399788.7) at chr12:280057-389320 -  ... with the viral protein-binding domain of RB1 Interacts with ESR1 <b>MYC</b> MYCN and LMO2 Nucleus nucleolus Note Occupies promoters of 
PNPT1 (ENST00000447944.7) at chr2:55634061-55693844 -  ... a 3 to-5 exoribonuclease mediating mRNA degradation activity degrades c <b>myc</b> mRNA upon treatment with IFNB1 IFN-beta resulting in a 
TOP1 (ENST00000361337.3) at chr20:41028822-41124487 -  ... Large T antigen this interactions allows viral DNA replication P01106 <b>MYC</b> NbExp 2 IntAct EBI-876302 EBI-447544 Q99801 NKX3-1 NbExp 6 
EPC1 (ENST00000319778.11) at chr10:32267751-32347158 -  ... BAF53A VPS72 and YEATS4 GAS41 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein EPC1 interacts with TRIM27 
KAT5 (ENST00000341318.9) at chr11:65712252-65719604 -  ... HAT complex termed Piccolo NuA4 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein Interacts with ATM Interacts 
POU5F1 (ENST00000429603.2) at chr6_GL000251v2_alt:2646761-2653135 -  ... WWP2 leading to proteasomal degradation By similarity POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
POU5F1 (ENST00000434616.2) at chr6_GL000252v2_alt:2423653-2430027 -  ... WWP2 leading to proteasomal degradation By similarity POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
POU5F1 (ENST00000383524.4) at chr6_GL000255v2_alt:2422370-2428743 -  ... WWP2 leading to proteasomal degradation By similarity POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
POU5F1 (ENST00000454714.6) at chr6_GL000253v2_alt:2474838-2481213 -  ... WWP2 leading to proteasomal degradation By similarity POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
POU5F1 (ENST00000433063.6) at chr6_GL000254v2_alt:2508452-2514827 -  ... WWP2 leading to proteasomal degradation By similarity POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
POU5F1 (ENST00000437747.6) at chr6_GL000256v2_alt:2467753-2474125 -  ... WWP2 leading to proteasomal degradation By similarity POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
MCM7 (ENST00000303887.10) at chr7:100092728-100101397 -  ... EBI-355924 EBI-374938 Q14566 MCM6 NbExp 4 IntAct EBI-355924 EBI-374900 P01106 <b>MYC</b> NbExp 6 IntAct EBI-355924 EBI-447544 P53350 PLK1 NbExp 4 
POU5F1 (ENST00000259915.13) at chr6:31164337-31170682 -  ... WWP2 leading to proteasomal degradation By similarity POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
SOX2 (ENST00000325404.3) at chr3:181711925-181714436 -  ... microphthalmia and esophageal atresia with trachoesophageal fistula POU5F1 OCT4 SOX2 <b>MYC</b> c-Myc and KLF4 are the four Yamanaka factors When 
RUVBL2 (ENST00000595090.6) at chr19:48993887-49015970 -  ... DNA repair Plays an essential role in oncogenic transformation by <b>MYC</b> and also modulates transcriptional activation by the LEF1 TCF1-CTNNB1 
CSNK2A2 (ENST00000262506.8) at chr16:58157907-58198106 -  ... NF-kappa-B STAT1 CREB1 IRF1 IRF2 ATF1 SRF MAX JUN FOS <b>MYC</b> and MYB Phosphorylates Hsp90 and its co-chaperones FKBP4 and 
SP1 (ENST00000327443.9) at chr12:53380176-53416446 -  ... EBI-298336 EBI-396176 Q13118 KLF10 NbExp 2 IntAct EBI-298336 EBI-1389509 P01106 <b>MYC</b> NbExp 4 IntAct EBI-298336 EBI-447544 P16333 NCK1 NbExp 2 
PIAS2 (ENST00000585916.6) at chr18:46803218-46917507 -  ... into G 1 phase PIAS2-beta interacts with IFIH1 MDA5 P01106 <b>MYC</b> NbExp 4 IntAct EBI-348555 EBI-447544 Q96T51 RUFY1 NbExp 3 
FGF9 (ENST00000382353.6) at chr13:21671073-21704498 -  ... activity of the MAPK1 MAPK2 pathway and decreases CTNNB1 and <b>MYC</b> expression when compared with wild-type protein Binding of mutant 
PRKCB (ENST00000643927.1) at chr16:23835983-24220611 -  ... the inhibition of the insulin gene transcription via regulation of <b>MYC</b> expression In endothelial cells activation of PRKCB induces increased 
HDAC2 (ENST00000519065.6) at chr6:113933028-113971148 -  ... EBI-301821 EBI-301834 Q9UIS9 MBD1 NbExp 2 IntAct EBI-301821 EBI-867196 P01106 <b>MYC</b> NbExp 2 IntAct EBI-301821 EBI-447544 P48382 RFX5 NbExp 4 
SIRT1 (ENST00000212015.11) at chr10:67884656-67918390 -  ... thereby represses rDNA transcription by the RNA polymerase I Deacetylates <b>MYC</b> promotes the association of MYC with MAX and decreases 
PEG10 (ENST00000488574.5) at chr7:94656370-94665698 -  ... and highly activated at 11-12 week of gestation Up-regulated by <b>MYC</b> and dihydrotestosterone DHT Isoform RF1 RF2 undergoes proteolytic cleavage 
ACTL6A (ENST00000429709.7) at chr3:179562926-179588407 -  ... GAS41 VPS72 YL1 and MEAF6 The NuA4 complex interacts with <b>MYC</b> and the adenovirus E1A protein Component of a NuA4-related 
CHUK (ENST00000370397.8) at chr10:100188300-100229596 -  ... EBI-81249 EBI-81279 Q99558 MAP3K14 NbExp 4 IntAct EBI-81249 EBI-358011 P01106 <b>MYC</b> NbExp 3 IntAct EBI-81249 EBI-447544 P25963 NFKBIA NbExp 6 
CDK4 (ENST00000257904.11) at chr12:57747727-57752310 -  ... EBI-295644 EBI-375053 P42772 CDKN2B NbExp 3 IntAct EBI-295644 EBI-711280 P01106 <b>MYC</b> NbExp 2 IntAct EBI-295644 EBI-447544 P28749 RBL1 NbExp 2 
MYCL-AS1 (ENST00000418255.1) at chr1:39897745-39899098 - <b>MYCL-AS1</b> ENST00000418255.1 MYCL-AS1 from geneSymbol uc057fdi.1 uc057fdi.1 
MYCL (ENST00000372816.3) at chr1:39895428-39901917 - <b>MYCL</b> ENST00000372816.3 Homo sapiens MYCL proto-oncogene bHLH transcription factor MYCL 
MYCN (ENST00000281043.4) at chr2:15940550-15947004 - <b>MYCN</b> ENST00000281043.4 Homo sapiens MYCN proto-oncogene bHLH transcription factor MYCN 
MYCT1 (ENST00000367245.6) at chr6:152697897-152724569 - <b>MYCT1</b> ENST00000367245.6 Homo sapiens MYC target 1 MYCT1 transcript variant 
MYCNOS (ENST00000641950.2) at chr2:15918350-15941248 - MYCNOS ENST00000641950.2 <b>MYCN</b> opposite strand from HGNC MYCNOS ENST00000641950.1 S49953 uc061gvl.1 uc061gvl.2 
MYCNUT (ENST00000433810.1) at chr2:15920399-15936017 - MYCNUT ENST00000433810.1 Homo sapiens <b>MYCN</b> upstream transcript MYCNUT long non-coding RNA from RefSeq NR_125783 
MYOCD (ENST00000425538.6) at chr17:12665890-12768949 -  ... 3 mRNA from RefSeq NM_001378306 ENST00000425538.1 ENST00000425538.2 ENST00000425538.3 ENST00000425538.4 ENST00000425538.5 <b>MYCD</b> MYCD_HUMAN NM_001378306 Q5UBU5 Q8IZQ8 Q8N7Q1 uc002gno.1 uc002gno.2 uc002gno.3 uc002gno.4 
SLC2A13 (ENST00000280871.9) at chr12:39755025-40106081 -  ... RefSeq NM_052885 ENST00000280871.1 ENST00000280871.2 ENST00000280871.3 ENST00000280871.4 ENST00000280871.5 ENST00000280871.6 ENST00000280871.7 ENST00000280871.8 <b>MYCT_HUMAN</b> NM_052885 Q17S07 Q96QE2 uc010skm.1 uc010skm.2 uc010skm.3 H myo-inositol cotransporter 
HUWE1 (ENST00000262854.11) at chrX:53532096-53686719 -  ... differentiation and proliferation by catalyzing the polyubiquitination and degradation of <b>MYCN</b> May regulate abundance of CDC6 after DNA damage by 
AURKA (ENST00000395915.8) at chr20:56369390-56392215 -  ... PLK1 phosphorylation Q9NWT8 AURKAIP1 NbExp 2 IntAct EBI-448680 EBI-448665 P04198 <b>MYCN</b> NbExp 2 IntAct EBI-448680 EBI-878369 Q8VDQ8 Sirt2 xeno NbExp 
MYCBP (ENST00000397572.5) at chr1:38862493-38873348 - <b>MYCBP</b> ENST00000397572.5 Homo sapiens MYC binding protein MYCBP transcript variant 
MYCBP2-AS1 (ENST00000636737.1) at chr13:77026767-77077951 - <b>MYCBP2-AS1</b> ENST00000636737.1 MYCBP2 antisense RNA 1 from HGNC MYCBP2-AS1 uc285lay.1 
MYCBP2 (ENST00000544440.7) at chr13:77044657-77327094 - <b>MYCBP2</b> ENST00000544440.7 Homo sapiens MYC binding protein 2 MYCBP2 mRNA 
MYCBP2-AS2 (ENST00000428716.2) at chr13:77080511-77081190 - <b>MYCBP2-AS2</b> ENST00000428716.2 MYCBP2 antisense RNA 2 from HGNC MYCBP2-AS2 ENST00000428716.1 
MYCBPAP (ENST00000323776.11) at chr17:50508439-50531501 - MYCBPAP ENST00000323776.11 Homo sapiens <b>MYCBP</b> associated protein MYCBPAP transcript variant 3 non-coding RNA from 
ENSG00000274944 (ENST00000621281.1) at chr1:38864529-38881602 -  ... the neighboring GJA9 gap junction protein alpha 9 59kDa and <b>MYCBP</b> c-myc binding protein genes on chromosome 1 Alternative splicing 
CFAP91 (ENST00000273390.9) at chr3:119703022-119767102 -  ... with AMY1 Q92667-2 AKAP1 NbExp 3 IntAct EBI-2119735 EBI-2120060 Q99417 <b>MYCBP</b> NbExp 5 IntAct EBI-2119735 EBI-716185 Cytoplasm Mitochondrion Note Isoform 
AKAP1 (ENST00000337714.8) at chr17:57085246-57121344 -  ... outer membrane Q7Z4T9-4 AAT1 NbExp 3 IntAct EBI-2120060 EBI-2119735 Q99417 <b>MYCBP</b> NbExp 2 IntAct EBI-2120060 EBI-716185 Mitochondrion outer membrane Potential 
FBXO45 (ENST00000311630.7) at chr3:196568660-196589059 -  ... and degradation Protein modification protein ubiquitination Forms a complex with <b>MYCBP2</b> and SKP1 but does not appear to form an 
ARFGEF1 (ENST00000262215.8) at chr8:67197658-67343781 -  ... EBI-1044254 EBI-2691397 Q7Z4S6-2 KIF21A NbExp 4 IntAct EBI-1044254 EBI-6251716 Q99417 <b>MYCBP</b> NbExp 3 IntAct EBI-1044254 EBI-716185 Q13459-2 MYO9B NbExp 2 
ARFGEF2 (ENST00000371917.5) at chr20:48921711-49036693 -  ... complexes Interacts with PRKAR1A PRKAR2A PRKAR1B PRKAR2B PPP1CC PDE3A TNFRSF1A <b>MYCBP</b> and EXOC7 Interacts with GABRB1 GABRB2 and GABRB3 By