Your search resulted in multiple matches. Please select a position:

Gencode Genes

ITGB2 (ENST00000652462.1) at chr21:44885953-44920899 - <b>ITGB2</b> ENST00000652462.1 Homo sapiens integrin subunit beta 2 ITGB2 transcript 
ITGB2-AS1 (ENST00000441379.5) at chr21:44921051-44929678 - <b>ITGB2-AS1</b> ENST00000441379.5 Homo sapiens ITGB2 antisense RNA 1 ITGB2-AS1 transcript 
ITGAX (ENST00000268296.9) at chr16:31355176-31382999 -  ... beta chain This protein combines with the beta 2 chain <b>ITGB2</b> to form a leukocyte-specific integrin referred to as inactivated-C3b 
ITGAM (ENST00000544665.9) at chr16:31259975-31332877 -  ... I-domain containing alpha integrin combines with the beta 2 chain <b>ITGB2</b> to form a leukocyte-specific integrin referred to as macrophage 
ITGAL (ENST00000356798.11) at chr16:30472742-30523185 -  ... I-domain containing alpha integrin combines with the beta 2 chain <b>ITGB2</b> to form the integrin lymphocyte function-associated antigen-1 LFA-1 which 
P2RX7 (ENST00000328963.10) at chr12:121132876-121188032 -  ... are organized as homomeric and heteromeric trimers Interacts with LAMA3 <b>ITGB2</b> ACTB ACTN4 SVIL MPP3 HSPA1 HSPCB HSPA8 PIK230 and 
RANBP9 (ENST00000011619.6) at chr6:13621498-13711835 -  ... to intracellular signaling pathways May be involved in signaling of <b>ITGB2</b> LFA-1 and other integrins Enhances HGF-MET signaling by recruiting 
PIK3R1 (ENST00000521381.6) at chr5:68215756-68301821 -  ... SCF KIT PDGFRA and PDGFRB Likewise plays a role in <b>ITGB2</b> signaling Heterodimer of a regulatory subunit PIK3R1 and a 
FERMT3 (ENST00000345728.10) at chr11:64206721-64223891 -  ... in hematopoietic cells Acts by activating the integrin beta-1-3 ITGB1 <b>ITGB2</b> and ITGB3 Required for integrin-mediated platelet adhesion and leukocyte 
YWHAZ (ENST00000395958.6) at chr8:100916523-100952020 -  ... it in the cytoplasm By similarity Interacts with Thr phosphorylated <b>ITGB2</b> By similarity Interacts with BCL2L11 By similarity Homodimer Heterodimerizes 
HCK (ENST00000375852.5) at chr20:32052242-32101856 -  ... IL2 IL6 and IL8 and integrins such as ITGB1 and <b>ITGB2</b> During the phagocytic process mediates mobilization of secretory lysosomes 
FGR (ENST00000374005.8) at chr1:27612064-27635185 -  ... FCER1B FCGR2A and or FCGR2B Acts downstream of ITGB1 and <b>ITGB2</b> and regulates actin cytoskeleton reorganization cell spreading and adhesion 
VAV3 (ENST00000370056.9) at chr1:107571161-107965180 -  ... preceding macrophage phagocytosis of apoptotic neutrophils Responsible for integrin beta-2 <b>ITGB2</b> mediated macrophage adhesion and to a lesser extent contributes 
STAB2 (ENST00000388887.7) at chr12:103587273-103766719 -  ... and heparin Also interacts with alpha-M beta-2 integrin ITGAM and <b>ITGB2</b> and thymosin beta 4 TMSB4X and or TMSB4Y Cell 
MYLK (ENST00000360304.8) at chr3:123610049-123884332 -  ... cells and tumor metastasis PTK2B PYK2 activation by phosphorylation mediates <b>ITGB2</b> activation and is thus essential to trigger neutrophil transmigration 
COPS5 (ENST00000357849.9) at chr8:67043079-67062133 -  ... HIF1A CDKN1B BCL3 GFER PGR LHCGR SMAD4 SMAD7 ID1 ID3 <b>ITGB2</b> and TOP2A Part of a complex consisting of RANBP9 
SYK (ENST00000375754.9) at chr9:90801819-90898549 -  ... mediates neutrophils and macrophages integrin-mediated activation By similarity Interacts with <b>ITGB2</b> and FGR involved in ITGB2 downstream signaling By similarity 
PTK2B (ENST00000346049.10) at chr8:27325552-27459386 -  ... induce autophosphorylation and increase kinase activity Phosphorylation by MYLK promotes <b>ITGB2</b> activation and is thus essential to trigger neutrophil transmigration