Your search resulted in multiple matches. Please select a position:

Gencode Genes

HCK (ENST00000375852.5) at chr20:32052242-32101856 - <b>HCK</b> ENST00000375852.5 Homo sapiens HCK proto-oncogene Src family tyrosine kinase 
CSK (ENST00000220003.14) at chr15:74782080-74803197 -  ... the C-terminal tails of Src-family kinases SFKs including LCK SRC <b>HCK</b> FYN LYN or YES1 Upon tail phosphorylation Src-family members 
FCGR1A (ENST00000369168.5) at chr1:149782694-149791675 -  ... FCGR1A degradation Interacts with EPB41L2 LAT and PPL Interacts with <b>HCK</b> and LYN Cell membrane Single-pass type I membrane protein 
FCGR2A (ENST00000271450.12) at chr1:161505457-161519829 -  ... regulating its function Interacts with APCS and FGR Interacts with <b>HCK</b> Cell membrane Single-pass type I membrane protein Event Alternative 
GAB1 (ENST00000262994.9) at chr4:143336876-143474565 -  ... GAB1 PIK3R1 and SOS1 Interacts phosphorylated with PTPN11 Interacts with <b>HCK</b> Q06124 PTPN11 NbExp 3 IntAct EBI-517684 EBI-297779 Event Alternative 
ELMO1 (ENST00000310758.9) at chr7:36852906-37448864 -  ... DOCK1 and CRK isoform CRK-II Interacts with PLEKHG6 Interacts with <b>HCK</b> via SH3 domain Q14185 DOCK1 NbExp 5 IntAct EBI-346417 
WIPF1 (ENST00000679041.1) at chr2:174559574-174597804 -  ... EBI-346356 EBI-397955 P62993 GRB2 NbExp 3 IntAct EBI-346356 EBI-401755 P08631 <b>HCK</b> NbExp 3 IntAct EBI-346356 EBI-346340 P16333 NCK1 NbExp 2 
BCR (ENST00000305877.13) at chr22:23180509-23318037 -  ... Interacts with FES FPS ABL1 PIK3R1 and GRB2 Interacts with <b>HCK</b> Q9H2K2 TNKS2 NbExp 3 IntAct EBI-712838 EBI-4398527 Event Alternative 
VAV1 (ENST00000602142.6) at chr19:6772708-6857361 -  ... SHB and CLNK By similarity Interacts with THEMIS2 Interacts with <b>HCK</b> By similarity Interacts with NEK3 and this interaction is 
GAB2 (ENST00000361507.5) at chr11:78215293-78417820 -  ... prevents interaction with GRB2 and attenuates GAB2 signaling Interacts with <b>HCK</b> P62993 GRB2 NbExp 4 IntAct EBI-975200 EBI-401755 Cytoplasm Cell 
SKAP2 (ENST00000345317.7) at chr7:26667068-26864590 -  ... with LAT GRB2 PTK2B and PRAM1 May interact with FYN <b>HCK</b> and LYN Interacts with FASLG Cytoplasm Ubiquitously expressed Present 
IL6ST (ENST00000381298.7) at chr5:55935095-55994963 -  ... two molecules each of IL6 IL6R and IL6ST Interacts with <b>HCK</b> P42227 Stat3 xeno NbExp 2 IntAct EBI-1030834 EBI-602878 Isoform 
TP73 (ENST00000378295.9) at chr1:3652516-3736201 -  ... B30.2 SPRY domain Interacts with YAP1 phosphorylated form Interacts with <b>HCK</b> via SH3 domain this inhibits TP73 activity and degradation 
TRPV4 (ENST00000261740.7) at chr12:109783089-109833398 -  ... Map7 and Src family Tyr protein kinases LYN SRC FYN <b>HCK</b> LCK and YES Interacts with CTNNB1 The TRPV4 and 
KHDRBS1 (ENST00000327300.12) at chr1:32013868-32043877 -  ... EBI-1364 EBI-515315 P62993 GRB2 NbExp 8 IntAct EBI-1364 EBI-401755 P08631 <b>HCK</b> NbExp 2 IntAct EBI-1364 EBI-346340 P52333 JAK3 NbExp 2 
FLT3 (ENST00000241453.12) at chr13:28003274-28100576 -  ... ligand activation By similarity Interacts with FES FER LYN FGR <b>HCK</b> SRC and GRB2 Interacts with PTPRJ DEP-1 and PTPN11 
WAS (ENST00000376701.5) at chrX:48683799-48691427 -  ... via SH3 domains By similarity Interacts with CDC42 RAC NCK <b>HCK</b> FYN SRC kinase FGR BTK ABL1 PSTPIP1 WIP and 
CHST15 (ENST00000435907.6) at chr10:124007668-124093598 -  ... unsure May interact with phosphorylated proteins in resting B-cells including <b>HCK</b> Golgi apparatus membrane Single-pass type II membrane protein Probable 
CBL (ENST00000264033.6) at chr11:119206339-119308149 -  ... EGFR CSF1R EPHA8 and KDR and terminates signaling Recognizes membrane-bound <b>HCK</b> and other kinases of the SRC family and mediates 
YAP1 (ENST00000282441.10) at chr11:102110447-102233424 -  ... and TEAD4 Interacts with TP73 Interacts with RUNX1 Interacts with <b>HCK</b> Q15797 SMAD1 NbExp 3 IntAct EBI-1044059 EBI-1567153 Cytoplasm Nucleus 
PIK3R1 (ENST00000521381.6) at chr5:68215756-68301821 -  ... FGFR1 FGFR2 FGFR3 and FGFR4 phosphorylated Interacts with FGR and <b>HCK</b> Interacts with PDGFRA tyrosine phosphorylated and PDGFRB tyrosine phosphorylated 
STAT5B (ENST00000293328.8) at chr17:42199177-42276391 -  ... be phosphorylated by JAK2 Phosphoryation at Tyr-699 by PTK6 or <b>HCK</b> leads to an increase of its transcriptional activity Defects 
ADAM15 (ENST00000356955.7) at chr1:155051316-155062775 -  ... PTKs Interacts with SH3PXD2A Interacts with ITAGV-ITGB1 Interacts with GRB2 <b>HCK</b> ITSN1 ITSN2 LYN MAPK1 MAPK3 NCF1 NCK1 nephrocystin PTK6 
FES (ENST00000328850.8) at chr15:90884504-90895776 -  ... Phosphorylated by LYN in response to FCER1 activation Phosphorylated by <b>HCK</b> Note Has been shown to act as proto-oncogene in 
ITGB1 (ENST00000302278.8) at chr10:32900318-32958230 -  ... RAB25 via the hypervariable C-terminal region Interacts with FGR and <b>HCK</b> By similarity Interacts with MYO10 Interacts with DAB2 Interacts 
SH3KBP1 (ENST00000397821.8) at chrX:19533977-19887600 -  ... of SRC tyrosine-protein kinases SRC LCK LYN FGR FYN and <b>HCK</b> Interacts with TRADD BIRC2 TRAF1 TRAF2 and TNFR1 and 
ABL1 (ENST00000318560.6) at chr9:130835254-130887675 -  ... Interacts with CABLES1 and PSTPIP1 Interacts with ZDHHC16 ITGB1 and <b>HCK</b> By similarity Interacts with INPPL1 SHIP2 Interacts with the 
ARRB1 (ENST00000420843.7) at chr11:75260122-75351661 -  ... MAPK3 activated By similarity Interacts with MAP2K4 MKK4 Interacts with <b>HCK</b> and CXCR1 phosphorylated P62158 CALM3 NbExp 3 IntAct EBI-743313 
ARRB2 (ENST00000269260.7) at chr17:4710632-4721497 -  ... activation of MAPK1 and MAPK3 Interacts with GPR143 Interacts with <b>HCK</b> and CXCR1 phosphorylated P31750 Akt1 xeno NbExp 3 IntAct 
CSNK1D (ENST00000314028.11) at chr17:82242667-82273700 -  ... ENST00000314028.1 ENST00000314028.10 ENST00000314028.2 ENST00000314028.3 ENST00000314028.4 ENST00000314028.5 ENST00000314028.6 ENST00000314028.7 ENST00000314028.8 ENST00000314028.9 <b>HCKID</b> KC1D_HUMAN NM_001893 P48730 Q96KZ6 Q9BTN5 uc002kej.1 uc002kej.2 uc002kej.3 uc002kej.4