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Gencode Genes

GNAZ (ENST00000615612.2) at chr22:23070519-23125032 - Homo sapiens G protein subunit alpha z (GNAZ), mRNA. (from RefSeq NM_002073)
GNAZ (ENST00000492538.1) at chr22:23070574-23095716 - G protein subunit alpha z (from HGNC GNAZ)
GNAZ (ENST00000479571.1) at chr22:23122378-23123342 - G protein subunit alpha z (from HGNC GNAZ)
GPRIN2 (ENST00000374314.5) at chr10:46549049-46550744 - May be involved in neurite outgrowth. (from UniProt O60269)
GPRIN2 (ENST00000374317.1) at chr10:46549044-46555530 - Homo sapiens G protein regulated inducer of neurite outgrowth 2 (GPRIN2), mRNA. (from RefSeq NM_014696)
GPRIN1 (ENST00000303991.5) at chr5:176595802-176610156 - Homo sapiens G protein regulated inducer of neurite outgrowth 1 (GPRIN1), mRNA. (from RefSeq NM_052899)
EYA2 (ENST00000497062.6) at chr20:46894870-47188844 - Tyrosine phosphatase that specifically dephosphorylates  'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation  of histone H2AX plays a central role in DNA repair and acts as a  mark that distinguishes between apoptotic and repair responses to  genotoxic stress. Promotes efficient DNA repair by  dephosphorylating H2AX, promoting the recruitment of DNA repair  complexes containing MDC1. Its function as histone phosphatase  probably explains its role in transcription regulation during  organogenesis. Coactivates SIX1. Seems to coactivate SIX2, SIX4  and SIX5. Together with SIX1 and DACH2 seem to be involved in  myogenesis. May be involved in development of the eye. Interaction  with GNAZ and GNAI2 prevents nuclear translocation and  transcriptional activity. (from UniProt O00167)
OPRM1 (ENST00000524150.2) at chr6:154039479-154246860 - Receptor for endogenous opioids such as beta-endorphin  and endomorphin. Receptor for natural and synthetic opioids  including morphine, heroin, DAMGO, fentanyl, etorphine,  buprenorphin and methadone. Agonist binding to the receptor  induces coupling to an inactive GDP-bound heterotrimeric G-protein  complex and subsequent exchange of GDP for GTP in the G-protein  alpha subunit leading to dissociation of the G-protein complex  with the free GTP-bound G-protein alpha and the G-protein beta-  gamma dimer activating downstream cellular effectors. The agonist-  and cell type-specific activity is predominantly coupled to  pertussis toxin-sensitive G(i) and G(o) G alpha proteins, GNAI1,  GNAI2, GNAI3 and GNAO1 isoforms Alpha-1 and Alpha-2, and to a  lesser extend to pertussis toxin-insensitive G alpha proteins GNAZ  and GNA15. They mediate an array of downstream cellular responses,  including inhibition of adenylate cyclase activity and both N-type  and L-type calcium channels, activation of inward rectifying  potassium channels, mitogen-activated protein kinase (MAPK),  phospholipase C (PLC), phosphoinositide/protein kinase (PKC),  phosphoinositide 3-kinase (PI3K) and regulation of NF-kappa-B.  Also couples to adenylate cyclase stimulatory G alpha proteins.  The selective temporal coupling to G-proteins and subsequent  signaling can be regulated by RGSZ proteins, such as RGS9, RGS17  and RGS4. Phosphorylation by members of the GPRK subfamily of  Ser/Thr protein kinases and association with beta-arrestins is  involved in short-term receptor desensitization. Beta-arrestins  associate with the GPRK-phosphorylated receptor and uncouple it  from the G-protein thus terminating signal transduction. The  phosphorylated receptor is internalized through endocytosis via  clathrin-coated pits which involves beta-arrestins. The activation  of the ERK pathway occurs either in a G-protein-dependent or a  beta-arrestin-dependent manner and is regulated by agonist-  specific receptor phosphorylation. Acts as a class A G-protein  coupled receptor (GPCR) which dissociates from beta-arrestin at or  near the plasma membrane and undergoes rapid recycling. Receptor  down-regulation pathways are varying with the agonist and occur  dependent or independent of G-protein coupling. Endogenous ligands  induce rapid desensitization, endocytosis and recycling whereas  morphine induces only low desensitization and endocytosis.  Heterooligomerization with other GPCRs can modulate agonist  binding, signaling and trafficking properties. Involved in  neurogenesis. Isoform 12 couples to GNAS and is proposed to be  involved in excitatory effects. Isoform 16 and isoform 17 do not  bind agonists but may act through oligomerization with binding-  competent OPRM1 isoforms and reduce their ligand binding activity. (from UniProt P35372)
EYA2 (ENST00000357410.7) at chr20:46894624-47188844 - Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 5, mRNA. (from RefSeq NM_172110)
EYA2 (ENST00000327619.10) at chr20:46894843-47188844 - Homo sapiens EYA transcriptional coactivator and phosphatase 2 (EYA2), transcript variant 1, mRNA. (from RefSeq NM_005244)
OPRM1 (ENST00000519083.5) at chr6:154039495-154109018 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1Y, non-coding RNA. (from RefSeq NR_104351)
OPRM1 (ENST00000522739.5) at chr6:154039475-154118807 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1Y3, non-coding RNA. (from RefSeq NR_104348)
OPRM1 (ENST00000522555.5) at chr6:154086507-154118969 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1K2, mRNA. (from RefSeq NM_001285526)
OPRM1 (ENST00000524163.5) at chr6:154039495-154107652 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1B4, mRNA. (from RefSeq NM_001145285)
OPRM1 (ENST00000518759.5) at chr6:154010501-154118809 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1G2, mRNA. (from RefSeq NM_001145281)
OPRM1 (ENST00000435918.6) at chr6:154039495-154109018 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1B2, mRNA. (from RefSeq NM_001145283)
OPRM1 (ENST00000419506.6) at chr6:154039495-154107652 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1B5, mRNA. (from RefSeq NM_001145286)
OPRM1 (ENST00000337049.8) at chr6:154039495-154246867 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1O, mRNA. (from RefSeq NM_001008503)
OPRM1 (ENST00000229768.9) at chr6:154039495-154093520 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1X, mRNA. (from RefSeq NM_001008505)
OPRM1 (ENST00000522236.1) at chr6:154086507-154118969 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1K1, mRNA. (from RefSeq NM_001145287)
OPRM1 (ENST00000520708.5) at chr6:154010501-154118809 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1W, mRNA. (from RefSeq NM_001285527)
OPRM1 (ENST00000452687.6) at chr6:154039456-154110453 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1Y2, non-coding RNA. (from RefSeq NR_104349)
OPRM1 (ENST00000434900.6) at chr6:154010501-154118754 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1CA, mRNA. (from RefSeq NM_001285524)
OPRM1 (ENST00000428397.6) at chr6:154039349-154091593 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1A, mRNA. (from RefSeq NM_001008504)
OPRM1 (ENST00000414028.6) at chr6:154039495-154109018 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1B3, mRNA. (from RefSeq NM_001145284)
OPRM1 (ENST00000330432.12) at chr6:154039240-154132356 - Homo sapiens opioid receptor mu 1 (OPRM1), transcript variant MOR-1S, mRNA. (from RefSeq NM_001285522)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_002073.3 at chr22:23070349-23125037

NCBI RefSeq genes, predicted subset (XM_* or XR_*)

XM_017028786.2 at chr22:23070542-23114689
XR_937843.3 at chr22:23070542-23125037

NCBI RefSeq and Ensembl transcripts from the MANE Project (v0.6)

GNAZ at chr22:23070519-23125032

RefSeq Genes

GNAZ at chr22:23070519-23125032 - (NM_002073) guanine nucleotide-binding protein G(z) subunit alpha

Non-Human RefSeq Genes

GNAZ at chr22:23070491-23125033 - (NM_001261596) guanine nucleotide-binding protein G(z) subunit alpha
gnaz at chr22:23095687-23123431 - (NM_001079121) guanine nucleotide-binding protein G(z) subunit alpha
Gnaz at chr22:23095682-23123624 - (NM_013189) guanine nucleotide-binding protein G(z) subunit alpha
Gnaz at chr22:23070413-23125035 - (NM_001358848) guanine nucleotide-binding protein G(z) subunit alpha
Gnaz at chr22:23070413-23125035 - (NM_010311) guanine nucleotide-binding protein G(z) subunit alpha

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

GNAZ at chr22:23070519-23125032

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

GNAZ at chr22:23070519-23125032
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

GNAZ at chr22:23070361-23125037

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

GNAZ at chr22:23070361-23125037
GNAZ at chr22:23070574-23095716
GNAZ at chr22:23122378-23123342

International Knockout Mouse Consortium Genes Mapped to Human Genome

Gnaz_45760 at chr22:23070483-23125034
Gnaz_73491 at chr22:23070483-23125034
Gnaz_VG17377 at chr22:23070483-23125034

Alias of STS Marker

GNAZ at chr22:22996224-23196370 - (GNAZ)

Human Aligned mRNA Search Results

AF055013 - Homo sapiens clone 24695 guanine nucleotide-binding protein alpha-i subunit (GNAZ) mRNA, complete cds.
AF493899 - Homo sapiens guanine nucleotide binding protein alpha z (GNAZ) mRNA, complete cds.
BC026342 - Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide, mRNA (cDNA clone MGC:26547 IMAGE:4814858), complete cds.
BC037333 - Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide, mRNA (cDNA clone MGC:43258 IMAGE:5264642), complete cds.
BC078163 - Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide, mRNA (cDNA clone MGC:88028 IMAGE:6180193), complete cds.
BC096828 - Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide, mRNA (cDNA clone MGC:111695 IMAGE:6519151), complete cds.
CR456495 - Homo sapiens GNAZ full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.GNAZ.V4).
J03260 - Human transducin alpha-subunit (GNAZ) mRNA, complete cds.
M14631 - Human guanine nucleotide-binding protein G-s, alpha subunit mRNA, partial cds.
M17219 - Human brain guanine nucleotide-binding protein alpha-i subunit mRNA, 5' end.
AK312519 - Homo sapiens cDNA, FLJ92884, Homo sapiens guanine nucleotide binding protein (G protein), alphaz polypeptide (GNAZ), mRNA.

Non-Human Aligned mRNA Search Results

FJ958357 - Ovis aries GNAZ (GNAZ) mRNA, complete cds.
BC014702 - Mus musculus guanine nucleotide binding protein, alpha z subunit, mRNA (cDNA clone MGC:25486 IMAGE:4501587), complete cds.
JT406039 - TSA: Ictalurus punctatus clc_264772 mRNA sequence.
JU334060 - TSA: Macaca mulatta Mamu_501703 mRNA sequence.