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Gencode Genes

EPHA4 (ENST00000281821.7) at chr2:221418027-221572304 - Homo sapiens EPH receptor A4 (EPHA4), transcript variant 2, mRNA. (from RefSeq NM_004438)
EPHA4 (ENST00000541600.5) at chr2:221564106-221572358 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt F5GZZ5)
EPHA4 (ENST00000495693.1) at chr2:221436457-221437496 - EPH receptor A4 (from HGNC EPHA4)
EPHA4 (ENST00000472696.1) at chr2:221420445-221425540 - EPH receptor A4 (from HGNC EPHA4)
EPHA4 (ENST00000469354.1) at chr2:221418027-221425575 - EPH receptor A4 (from HGNC EPHA4)
EPHA4 (ENST00000463446.1) at chr2:221482440-221501344 - EPH receptor A4 (from HGNC EPHA4)
EPHA4 (ENST00000443796.5) at chr2:221457889-221572300 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt C9JFX5)
EPHA4 (ENST00000441679.1) at chr2:221457954-221502560 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt H7C1N8)
EPHA4 (ENST00000434266.1) at chr2:221564279-221574158 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt C9JIX8)
EPHA4 (ENST00000424339.1) at chr2:221425915-221434249 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt H7C2W7)
EPHA4 (ENST00000419964.1) at chr2:221563997-221569481 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt C9JEM6)
EPHA4 (ENST00000415749.1) at chr2:221563993-221572300 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt F8WBU0)
EPHA4 (ENST00000409938.5) at chr2:221425901-221574202 - Receptor tyrosine kinase which binds membrane-bound  ephrin family ligands residing on adjacent cells, leading to  contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as  forward signaling while the signaling pathway downstream of the  ephrin ligand is referred to as reverse signaling. Highly  promiscuous, it has the unique property among Eph receptors to  bind and to be physiologically activated by both GPI-anchored  ephrin-A and transmembrane ephrin-B ligands including EFNA1 and  EFNB3. Upon activation by ephrin ligands, modulates cell  morphology and integrin-dependent cell adhesion through regulation  of the Rac, Rap and Rho GTPases activity. Plays an important role  in the development of the nervous system controlling different  steps of axonal guidance including the establishment of the  corticospinal projections. May also control the segregation of  motor and sensory axons during neuromuscular circuit development.  Beside its role in axonal guidance plays a role in synaptic  plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15'  which in turn phosphorylates NGEF regulating RHOA and dendritic  spine morphogenesis. In the nervous system, plays also a role in  repair after injury preventing axonal regeneration and in  angiogenesis playing a role in central nervous system vascular  formation. Additionally, its promiscuity makes it available to  participate in a variety of cell-cell signaling regulating for  instance the development of the thymic epithelium. (from UniProt P54764)
EPHA4 (ENST00000409854.5) at chr2:221425599-221572283 - Homo sapiens EPH receptor A4 (EPHA4), transcript variant 4, mRNA. (from RefSeq NM_001363748)
NGEF (ENST00000409079.1) at chr2:232894602-232928154 - Acts as a guanine nucleotide exchange factor (GEF) which  differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a  role in axon guidance regulating ephrin-induced growth cone  collapse and dendritic spine morphogenesis. Upon activation by  ephrin through EPHA4, the GEF activity switches toward RHOA  resulting in its activation. Activated RHOA promotes cone  retraction at the expense of RAC1- and CDC42-stimulated growth  cone extension (By similarity). (from UniProt Q8N5V2)
NGEF (ENST00000373552.8) at chr2:232879215-232928154 - Homo sapiens neuronal guanine nucleotide exchange factor (NGEF), transcript variant 2, mRNA. (from RefSeq NM_001114090)
NGEF (ENST00000264051.8) at chr2:232878701-233013256 - Homo sapiens neuronal guanine nucleotide exchange factor (NGEF), transcript variant 1, mRNA. (from RefSeq NM_019850)
SIPA1L1 (ENST00000555818.5) at chr14:71529325-71741229 - Homo sapiens signal induced proliferation associated 1 like 1 (SIPA1L1), transcript variant 1, mRNA. (from RefSeq NM_015556)
SIPA1L1 (ENST00000381232.7) at chr14:71529325-71739405 - Homo sapiens signal induced proliferation associated 1 like 1 (SIPA1L1), transcript variant 2, mRNA. (from RefSeq NM_001284245)
SIPA1L1 (ENST00000358550.6) at chr14:71586281-71739401 - Homo sapiens signal induced proliferation associated 1 like 1 (SIPA1L1), transcript variant 8, mRNA. (from RefSeq NM_001354288)
CHN1 (ENST00000409156.7) at chr2:174799989-175005369 - Homo sapiens chimerin 1 (CHN1), transcript variant 2, mRNA. (from RefSeq NM_001025201)
CHN1 (ENST00000409900.8) at chr2:174799313-175005381 - Homo sapiens chimerin 1 (CHN1), transcript variant 1, mRNA. (from RefSeq NM_001822)
CHN1 (ENST00000295497.12) at chr2:174799313-174847555 - Homo sapiens chimerin 1 (CHN1), transcript variant 3, mRNA. (from RefSeq NM_001206602)
EFNA1 (ENST00000368406.2) at chr1:155127876-155134857 - Homo sapiens ephrin A1 (EFNA1), transcript variant 2, mRNA. (from RefSeq NM_182685)
EFNA1 (ENST00000368407.8) at chr1:155127876-155134899 - Homo sapiens ephrin A1 (EFNA1), transcript variant 1, mRNA. (from RefSeq NM_004428)
VAPB (ENST00000395802.7) at chr20:58389313-58445552 - Homo sapiens VAMP associated protein B and C (VAPB), transcript variant 2, mRNA. (from RefSeq NM_001195677)
ARHGEF15 (ENST00000421050.2) at chr17:8310822-8322514 - Homo sapiens Rho guanine nucleotide exchange factor 15 (ARHGEF15), transcript variant 2, mRNA. (from RefSeq NM_025014)
ARHGEF15 (ENST00000361926.8) at chr17:8310241-8322511 - Homo sapiens Rho guanine nucleotide exchange factor 15 (ARHGEF15), transcript variant 1, mRNA. (from RefSeq NM_173728)
KIDINS220 (ENST00000473731.5) at chr2:8728929-8837630 - Homo sapiens kinase D interacting substrate 220 (KIDINS220), transcript variant 8, mRNA. (from RefSeq NM_001348738)
KIDINS220 (ENST00000319688.5) at chr2:8757194-8837600 - Homo sapiens kinase D interacting substrate 220 (KIDINS220), transcript variant 14, mRNA. (from RefSeq NM_001348745)
KIDINS220 (ENST00000256707.7) at chr2:8728857-8837625 - Homo sapiens kinase D interacting substrate 220 (KIDINS220), transcript variant 1, mRNA. (from RefSeq NM_020738)
EFNB2 (ENST00000646441.1) at chr13:106489745-106535662 - Homo sapiens ephrin B2 (EFNB2), mRNA. (from RefSeq NM_004093)
CDK5R1 (ENST00000313401.4) at chr17:32486993-32491253 - Homo sapiens cyclin dependent kinase 5 regulatory subunit 1 (CDK5R1), mRNA. (from RefSeq NM_003885)
EFNA2 (ENST00000215368.4) at chr19:1285873-1301431 - Homo sapiens ephrin A2 (EFNA2), mRNA. (from RefSeq NM_001405)
CDK5 (ENST00000297518.4) at chr7:151054009-151057848 - Homo sapiens cyclin dependent kinase 5 (CDK5), transcript variant 2, mRNA. (from RefSeq NM_001164410)
CDK5 (ENST00000485972.6) at chr7:151053815-151057897 - Homo sapiens cyclin dependent kinase 5 (CDK5), transcript variant 1, mRNA. (from RefSeq NM_004935)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_004438.4 at chr2:221418027-221572358
NM_001304537.1 at chr2:221418027-221572358
NM_001304536.1 at chr2:221418027-221574202

NCBI RefSeq genes, predicted subset (XM_* or XR_*)

XM_005246374.3 at chr2:221418986-221572304

NCBI RefSeq and Ensembl transcripts from the MANE Project (v0.6)

EPHA4 at chr2:221418027-221572304

RefSeq Genes

EPHA4 at chr2:221418027-221572304 - (NM_004438) ephrin type-A receptor 4 isoform a precursor
EPHA4 at chr2:221418027-221574202 - (NM_001304536) ephrin type-A receptor 4 isoform a precursor
EPHA4 at chr2:221418027-221572304 - (NM_001304537) ephrin type-A receptor 4 isoform b
EPHA4 at chr2:221418027-221572304 - (NM_001363748) ephrin type-A receptor 4 isoform c precursor

Non-Human RefSeq Genes

epha4 at chr2:221418076-221572251 - (NM_001142103) ephrin type-A receptor 4 precursor
EPHA4 at chr2:221426028-221572248 - (NM_001134967) ephrin type-A receptor 4 precursor
EPHA4 at chr2:221425405-221572280 - (NM_001260870) ephrin type-A receptor 4 precursor
EPHA4 at chr2:221514908-221572277 - (NM_001083441) ephrin type-A receptor 4 precursor
Epha4 at chr2:221418030-221572305 - (NM_007936) ephrin type-A receptor 4 precursor
Epha4 at chr2:221418035-221572304 - (NM_001162411) ephrin type-A receptor 4 precursor
EPHA4 at chr2:221425601-221572248 - (NM_204781) ephrin type-A receptor 4 precursor
epha4.L at chr2:221425933-221572251 - (NM_001085992) ephrin type-A receptor 4-B precursor
epha4.S at chr2:221426028-221572251 - (NM_001096714) ephrin type-A receptor 4-A precursor
epha4a at chr2:221425969-221564394 - (NM_001005919) ephrin type-A receptor 4a isoform 2 precursor
epha4a at chr2:221425969-221564394 - (NM_001365171) ephrin type-A receptor 4a isoform 1 precursor
epha4b at chr2:221426499-221564394 - (NM_153658) eph receptor A4b precursor

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

EPHA4 at chr2:221418027-221572304
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418027-221572304
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

EPHA4 at chr2:221418027-221425575
EPHA4 at chr2:221418029-221572290
EPHA4 at chr2:221420445-221425540
EPHA4 at chr2:221425599-221572283
EPHA4 at chr2:221425901-221574202
EPHA4 at chr2:221425915-221434249
EPHA4 at chr2:221436457-221437496
EPHA4 at chr2:221457889-221572300
EPHA4 at chr2:221457954-221502560
EPHA4 at chr2:221482440-221501344
EPHA4 at chr2:221563993-221572300
EPHA4 at chr2:221563997-221569481
EPHA4 at chr2:221564106-221572358
EPHA4 at chr2:221564279-221574158

International Knockout Mouse Consortium Genes Mapped to Human Genome

Epha4_66074 at chr2:221418027-221572290
Epha4_81367 at chr2:221418027-221572290

Human Aligned mRNA Search Results

BC105002 - Homo sapiens EPH receptor A4, mRNA (cDNA clone MGC:132662 IMAGE:8144005), complete cds.
BC026327 - Homo sapiens EPH receptor A4, mRNA (cDNA clone MGC:26318 IMAGE:4814429), complete cds.
BC105000 - Homo sapiens EPH receptor A4, mRNA (cDNA clone MGC:132660 IMAGE:8144003), complete cds.
AK290306 - Homo sapiens cDNA FLJ78431 complete cds, highly similar to Homo sapiens EPH receptor A4 (EPHA4), mRNA.
AK225181 - Homo sapiens mRNA for ephrin receptor EphA4 variant, clone: CBR06796.
BC036860 - Homo sapiens mRNA similar to EphA4 (cDNA clone IMAGE:5165840).
AK312380 - Homo sapiens cDNA, FLJ92707, highly similar to Homo sapiens EphA4 (EPHA4), mRNA.

Non-Human Aligned mRNA Search Results

BC098529 - Danio rerio eph receptor A4a, mRNA (cDNA clone MGC:109882 IMAGE:2639282), complete cds.
LC382454 - Carassius auratus EphA4a mRNA for ephA4a protein, complete cds.
AF369381 - Danio rerio Eph receptor EphA4b (RTK2) mRNA, complete cds.
AY335759 - Synthetic construct Homo sapiens EphA4 (EPHA4) mRNA, partial cds.
EU232010 - Pantherophis guttatus EphA4 mRNA, partial cds.
AY667434 - Scyliorhinus canicula EphA4 mRNA, partial cds.
BC004782 - Mus musculus Eph receptor A4, mRNA (cDNA clone MGC:8084 IMAGE:3588285), complete cds.
BC133500 - Bos taurus EPH receptor A4, mRNA (cDNA clone MGC:142975 IMAGE:8316217), complete cds.
KM655611 - Danio rerio Epha4a mRNA, partial cds.
BC052164 - Mus musculus Eph receptor A4, mRNA (cDNA clone MGC:59362 IMAGE:6512978), complete cds.
JT409635 - TSA: Ictalurus punctatus clc_366228 mRNA sequence.
JU333343 - TSA: Macaca mulatta Mamu_514161 mRNA sequence.
AB794079 - Lacerta agilis EPHA4 mRNA for EPH receptor A4, partial cds.
EU983276 - Sus scrofa ephrin receptor A4 (EphA4) mRNA, complete cds.
AB736187 - Pelodiscus sinensis EphA4 mRNA for Eph receptor A4, partial cds.
AB173364 - Macaca fascicularis brain cDNA clone: QflA-22235, similar to human EphA4 (EPHA4), mRNA, RefSeq: NM_004438.3.
AB171643 - Macaca fascicularis brain cDNA clone: QflA-22251, similar to human EphA4 (EPHA4), mRNA, RefSeq: NM_004438.3.
AB171573 - Macaca fascicularis brain cDNA clone: QflA-13703, similar to human EphA4 (EPHA4), mRNA, RefSeq: NM_004438.3.