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Gencode Genes

DDB2 (ENST00000256996.9) at chr11:47214974-47239217 - <b>DDB2</b> ENST00000256996.9 Required for DNA repair Binds to DDB1 to 
WDR76 (ENST00000263795.11) at chr15:43827002-43868412 -  ... with CUL4A and or CUL4B Belongs to the WD repeat <b>DDB2</b> WDR76 family Contains 7 WD repeats heterochromatin DNA binding 
GPS1 (ENST00000578552.6) at chr17:82051898-82057470 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
COPS7B (ENST00000350033.8) at chr2:231786445-231809253 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
COPS2 (ENST00000388901.10) at chr15:49122727-49155599 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
COPS7A (ENST00000543155.6) at chr12:6724046-6731865 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
CUL4A (ENST00000375440.9) at chr13:113209613-113267108 -  ... substrate recognition component DCX DET1-COP1 directs ubiquitination of JUN DCX <b>DDB2</b> directs ubiquitination of XPC In association with RBX1 DDB1 
COPS3 (ENST00000268717.10) at chr17:17246616-17281246 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
COPS4 (ENST00000264389.7) at chr4:83035183-83075818 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
COPS8 (ENST00000354371.7) at chr2:237085889-237100474 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
CUL4B (ENST00000371322.11) at chrX:120523858-120560962 -  ... radiation induced DNA damage Targeted to UV damaged chromatin by <b>DDB2</b> and may be important for DNA repair and DNA 
COPS6 (ENST00000303904.8) at chr7:100088969-100092187 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
DDB1 (ENST00000301764.12) at chr11:61299451-61333105 -  ... single protein-coding transcript RefSeq-Attributes-END Required for DNA repair Binds to <b>DDB2</b> to form the UV damaged DNA-binding protein complex the 
COPS5 (ENST00000357849.9) at chr8:67043079-67062133 -  ... ligase activity of SCF-type complexes such as SCF CSA or <b>DDB2</b> The complex is also involved in phosphorylation of p53 
ABL1 (ENST00000318560.6) at chr9:130835254-130887675 -  ... apoptosis Many substrates are known mediators of DNA repair DDB1 <b>DDB2</b> ERCC3 ERCC6 RAD9A RAD51 RAD52 or WRN Activates the 
E2F1 (ENST00000343380.6) at chr20:33675477-33686385 -  ... BIR domains Interacts with human cytomegalovirus HHV-5 protein UL123 Q92466 <b>DDB2</b> NbExp 2 IntAct EBI-448924 EBI-1176171 Q9Y618 NCOR2 NbExp 2 
RBX1 (ENST00000216225.9) at chr22:40951378-40973309 -  ... Part of an E3 ligase complex composed of RBX1 DDB1 <b>DDB2</b> and CUL4A or CUL4B Interacts with UBE2M Part of 
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