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Gencode Genes

CC2D1A (ENST00000318003.11) at chr19:13906201-13930879 - Homo sapiens coiled-coil and C2 domain containing 1A (CC2D1A), mRNA. (from RefSeq NM_017721)
CC2D1A (ENST00000589679.5) at chr19:13919694-13923399 - coiled-coil and C2 domain containing 1A (from HGNC CC2D1A)
CC2D1A (ENST00000589606.5) at chr19:13906442-13930659 - Transcription factor that binds specifically to the DRE  (dual repressor element) and represses HTR1A gene transcription in  neuronal cells. The combination of calcium and ATP specifically  inactivates the binding with FRE. May play a role in the altered  regulation of HTR1A associated with anxiety and major depression.  Mediates HDAC-independent repression of HTR1A promoter in neuronal  cell. Performs essential function in controlling functional  maturation of synapses (By similarity). Plays distinct roles  depending on its localization. When cytoplasmic, acts as a  scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A  when nuclear. In the centrosome, regulates spindle pole  localization of the cohesin subunit SCC1/RAD21, thereby mediating  centriole cohesion during mitosis. (from UniProt Q6P1N0)
CC2D1A (ENST00000589224.1) at chr19:13923579-13927553 - coiled-coil and C2 domain containing 1A (from HGNC CC2D1A)
CC2D1A (ENST00000589138.5) at chr19:13918507-13929537 - coiled-coil and C2 domain containing 1A (from HGNC CC2D1A)
CC2D1A (ENST00000588932.1) at chr19:13920277-13923753 - coiled-coil and C2 domain containing 1A (from HGNC CC2D1A)
CC2D1A (ENST00000587508.1) at chr19:13923328-13930845 - coiled-coil and C2 domain containing 1A (from HGNC CC2D1A)
CC2D1A (ENST00000586955.5) at chr19:13913253-13930879 - coiled-coil and C2 domain containing 1A (from HGNC CC2D1A)
CC2D1A (ENST00000585896.5) at chr19:13906203-13920381 - coiled-coil and C2 domain containing 1A (from HGNC CC2D1A)
CDK1 (ENST00000373809.2) at chr10:60780153-60794852 - Plays a key role in the control of the eukaryotic cell  cycle by modulating the centrosome cycle as well as mitotic onset;  promotes G2-M transition, and regulates G1 progress and G1-S  transition via association with multiple interphase cyclins.  Required in higher cells for entry into S-phase and mitosis.  Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-  xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C,  CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1,  DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG,  FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1  proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR,  LATS1, MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1, MYB, NEFH, NFIC,  NPC/nuclear pore complex, PITPNM1/NIR2, NPM1, NCL, NUCKS1,  NPM1/numatrin, ORC1, PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53,  NONO/p54NRB, PAPOLA, PLEC/plectin, RB1, UL40/R2, RAB4A, RAP1GAP,  RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin,  STIP1, TEX14, beta-tubulins, MAPT/TAU, NEDD1, VIM/vimentin, TK1,  FOXO1, RUNX1/AML1 and RUNX2. CDK1/CDC2-cyclin-B controls  pronuclear union in interphase fertilized eggs. Essential for  early stages of embryonic development. During G2 and early  mitosis, CDC25A/B/C-mediated dephosphorylation activates  CDK1/cyclin complexes which phosphorylate several substrates that  trigger at least centrosome separation, Golgi dynamics, nuclear  envelope breakdown and chromosome condensation. Once chromosomes  are condensed and aligned at the metaphase plate, CDK1 activity is  switched off by WEE1- and PKMYT1-mediated phosphorylation to allow  sister chromatid separation, chromosome decondensation,  reformation of the nuclear envelope and cytokinesis. Inactivated  by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage  to stop cell cycle and genome replication at the G2 checkpoint  thus facilitating DNA repair. Reactivated after successful DNA  repair through WIP1-dependent signaling leading to CDC25A/B/C-  mediated dephosphorylation and restoring cell cycle progression.  In proliferating cells, CDK1-mediated FOXO1 phosphorylation at the  G2-M phase represses FOXO1 interaction with 14-3-3 proteins and  thereby promotes FOXO1 nuclear accumulation and transcription  factor activity, leading to cell death of postmitotic neurons. The  phosphorylation of beta-tubulins regulates microtubule dynamics  during mitosis. NEDD1 phosphorylation promotes PLK1-mediated NEDD1  phosphorylation and subsequent targeting of the gamma-tubulin ring  complex (gTuRC) to the centrosome, an important step for spindle  formation. In addition, CC2D1A phosphorylation regulates CC2D1A  spindle pole localization and association with SCC1/RAD21 and  centriole cohesion during mitosis. The phosphorylation of Bcl-  xL/BCL2L1 after prolongated G2 arrest upon DNA damage triggers  apoptosis. In contrast, CASP8 phosphorylation during mitosis  prevents its activation by proteolysis and subsequent apoptosis.  This phosphorylation occurs in cancer cell lines, as well as in  primary breast tissues and lymphocytes. EZH2 phosphorylation  promotes H3K27me3 maintenance and epigenetic gene silencing. CALD1  phosphorylation promotes Schwann cell migration during peripheral  nerve regeneration. (from UniProt P06493)
CDK1 (ENST00000395284.8) at chr10:60778478-60794852 - Homo sapiens cyclin dependent kinase 1 (CDK1), transcript variant 1, mRNA. (from RefSeq NM_001786)
CDK1 (ENST00000316629.8) at chr10:60778454-60794843 - Homo sapiens cyclin dependent kinase 1 (CDK1), transcript variant 2, mRNA. (from RefSeq NM_033379)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_017721.4 at chr19:13906143-13930880

NCBI RefSeq genes, predicted subset (XM_* or XR_*)

XM_024451565.1 at chr19:13906149-13930879
XM_005259974.3 at chr19:13906149-13930879
XM_024451564.1 at chr19:13906149-13930879
XM_024451563.1 at chr19:13906149-13930879
XM_005259973.3 at chr19:13906149-13930879
XM_024451562.1 at chr19:13906149-13930879

NCBI RefSeq and Ensembl transcripts from the MANE Project (v0.6)

CC2D1A at chr19:13906201-13930879

RefSeq Genes

CC2D1A at chr19:13906201-13930879 - (NM_017721) coiled-coil and C2 domain-containing protein 1A

Non-Human RefSeq Genes

CC2D1A at chr19:13906214-13930791 - (NM_001243031) coiled-coil and C2 domain-containing protein 1A
CC2D1A at chr19:13906230-13930791 - (NM_001098954) coiled-coil and C2 domain-containing protein 1A
Cc2d1a at chr19:13906411-13930877 - (NM_145970) coiled-coil and C2 domain-containing protein 1A
Cc2d1a at chr19:13906411-13930753 - (NM_001013869) coiled-coil and C2 domain-containing protein 1A

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906442-13930659

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

CC2D1A at chr19:13906201-13930879
CC2D1A at chr19:13906203-13920381
CC2D1A at chr19:13906442-13930659
CC2D1A at chr19:13913253-13930879
CC2D1A at chr19:13918507-13929537
CC2D1A at chr19:13919694-13923399
CC2D1A at chr19:13920277-13923753
CC2D1A at chr19:13923328-13930845
CC2D1A at chr19:13923579-13927553

Retroposed Genes V9, Including Pseudogenes

CC2D1A at chr1:22958149-22958922 - (AK023399.1-13)

International Knockout Mouse Consortium Genes Mapped to Human Genome

Cc2d1a_26642 at chr19:13906143-13930880
Cc2d1a_26643 at chr19:13906143-13930880

Human Aligned mRNA Search Results

BC048345 - Homo sapiens coiled-coil and C2 domain containing 1A, mRNA (cDNA clone IMAGE:5242270), partial cds.
BC113968 - Homo sapiens coiled-coil and C2 domain containing 1A, mRNA (cDNA clone IMAGE:40032936), partial cds.
BC064981 - Homo sapiens coiled-coil and C2 domain containing 1A, mRNA (cDNA clone MGC:71119 IMAGE:6585236), complete cds.

Non-Human Aligned mRNA Search Results

BC027028 - Mus musculus coiled-coil and C2 domain containing 1A, mRNA (cDNA clone MGC:38983 IMAGE:5363547), complete cds.
BC030439 - Synthetic construct Mus musculus coiled-coil and C2 domain containing 1A, mRNA (cDNA clone IMAGE:5373578), complete cds.
BC142501 - Bos taurus coiled-coil and C2 domain containing 1A, mRNA (cDNA clone MGC:151642 IMAGE:8224290), complete cds.
BC016188 - Mus musculus coiled-coil and C2 domain containing 1A, mRNA (cDNA clone MGC:27560 IMAGE:4482793), complete cds.
BC081948 - Rattus norvegicus coiled-coil and C2 domain containing 1A, mRNA (cDNA clone MGC:94029 IMAGE:7122187), complete cds.
DQ329239 - Mus musculus Freud-1 (Cc2d1a) mRNA, complete cds.
JU335134 - TSA: Macaca mulatta Mamu_509068 mRNA sequence.
JU476135 - TSA: Macaca mulatta Mamu_362762 mRNA sequence.