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Gencode Genes

CASP9 (ENST00000333868.10) at chr1:15491401-15524215 - <b>CASP9</b> ENST00000333868.10 Homo sapiens caspase 9 CASP9 transcript variant 5 
EFHD2 (ENST00000375980.9) at chr1:15409888-15430339 -  ... through the regulation of BCL2L1 abundance By similarity Interacts with <b>CASP9</b> with inactive form Membrane raft By similarity Note In 
FAM162A (ENST00000477892.5) at chr3:122384182-122412334 -  ... cells implicating cytochrome C release and caspase activation such as <b>CASP9</b> and inducing mitochondrial permeability transition May be involved in 
CASP8 (ENST00000673742.1) at chr2:201260536-201287709 -  ... in the DISC Cleaves and activates CASP3 CASP4 CASP6 CASP7 <b>CASP9</b> and CASP10 May participate in the GZMB apoptotic pathways 
MZB1 (ENST00000302125.9) at chr5:139387467-139389913 -  ... heavy chains By similarity Isoform 2 interacts with CASP2 and <b>CASP9</b> Isoform 1 Endoplasmic reticulum By similarity Isoform 2 Cytoplasm 
BIRC7 (ENST00000217169.8) at chr20:63235905-63240495 -  ... activity is mediated through the inhibition of CASP3 CASP7 and <b>CASP9</b> as well as by its E3 ubiquitin-protein ligase activity 
HAX1 (ENST00000328703.12) at chr1:154272629-154275875 -  ... in internalization of ABC transporters such as ABCB11 May inhibit <b>CASP9</b> and CASP3 May regulate intracellular calcium pools Interacts with 
XIAP (ENST00000371199.8) at chrX:123860053-123913972 -  ... pocket of CASP3 and CASP7 and obstructs substrate entry Inactivates <b>CASP9</b> by keeping it in a monomeric inactive state Acts 
TAOK2 (ENST00000308893.9) at chr16:29973868-29988393 -  ... C-terminally truncated isoform 1 may be linked to the mitochondrial <b>CASP9-associated</b> death pathway Isoform 1 binds to microtubules and affects 
BIRC6 (ENST00000421745.7) at chr2:32357023-32618878 -  ... forming a chimeric E2 E3 ubiquitin ligase Its tragets include <b>CASP9</b> and DIABLO SMAC Acts as an inhibitor of CASP3 
APAF1 (ENST00000551964.6) at chr12:98645290-98735433 -  ... and NACHT domains with NAIP BIRC1 via NACHT domain P55211 <b>CASP9</b> NbExp 17 IntAct EBI-446492 EBI-516799 P99999 CYCS NbExp 6 
NAIP (ENST00000517649.6) at chr5:70968166-71025339 -  ... which acts by inhibiting the activities of CASP3 CASP7 and <b>CASP9</b> Can inhibit the autocleavage of pro-CASP9 and cleavage of 
CSNK2A1 (ENST00000217244.9) at chr20:472498-543790 -  ... UV irradiation Can also negatively regulate apoptosis Phosphorylates the caspases <b>CASP9</b> and CASP2 and the apoptotic regulator NOL3 Phosphorylation protects 
CSNK2A2 (ENST00000262506.8) at chr16:58157907-58198106 -  ... UV irradiation Can also negatively regulate apoptosis Phosphorylates the caspases <b>CASP9</b> and CASP2 and the apoptotic regulator NOL3 Phosphorylation protects 
MAPK3 (ENST00000263025.9) at chr16:30114105-30123220 -  ... SORBS3 or STMN1 regulators of apoptosis such as BAD BTG2 <b>CASP9</b> DAPK1 IER3 MCL1 or PPARG regulators of translation such 
BIRC2 (ENST00000227758.7) at chr11:102347214-102378670 -  ... with PRSS25 these interactions inhibit apoptotic suppressor activity Interacts with <b>CASP9</b> Interacts via BIR domains with TRAF2 Interacts with E2F1 
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