Your search resulted in multiple matches. Please select a position:

Gencode Genes

BRCA1 (ENST00000471181.7) at chr17:43044295-43125483 - Homo sapiens BRCA1 DNA repair associated (BRCA1), transcript variant 2, mRNA. (from RefSeq NM_007300)
BRCA1 (ENST00000652672.1) at chr17:43093585-43125483 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000644555.1) at chr17:43104225-43125326 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000644379.1) at chr17:43045086-43091851 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000642945.1) at chr17:43094482-43125343 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000634433.1) at chr17:43093013-43170245 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000621897.1) at chr17:43076488-43082760 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000618469.1) at chr17:43124026-43125364 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000591849.5) at chr17:43045563-43125329 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000591534.5) at chr17:43045563-43125329 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000586385.5) at chr17:43045563-43125329 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000497488.1) at chr17:43094112-43125300 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt C9IZW4)
BRCA1 (ENST00000494123.5) at chr17:43094112-43125450 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000493919.5) at chr17:43063360-43125402 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000493795.5) at chr17:43045629-43125402 - Homo sapiens BRCA1 DNA repair associated (BRCA1), transcript variant 3, mRNA. (from RefSeq NM_007297)
BRCA1 (ENST00000492859.5) at chr17:43094112-43125300 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt E9PC22)
BRCA1 (ENST00000491747.6) at chr17:43045678-43125356 - Homo sapiens BRCA1 DNA repair associated (BRCA1), transcript variant 4, mRNA. (from RefSeq NM_007298)
BRCA1 (ENST00000489037.1) at chr17:43104189-43125321 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt E7ENB7)
BRCA1 (ENST00000487825.5) at chr17:43076488-43104916 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt H0Y881)
BRCA1 (ENST00000484087.5) at chr17:43063344-43104916 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt H0Y8B8)
BRCA1 (ENST00000478531.5) at chr17:43063344-43125359 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt E7EUM2)
BRCA1 (ENST00000477152.5) at chr17:43093586-43125364 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt E9PH68)
BRCA1 (ENST00000476777.5) at chr17:43095846-43125353 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt E7EQW4)
BRCA1 (ENST00000473961.5) at chr17:43094170-43104891 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt H0Y8D8)
BRCA1 (ENST00000472490.1) at chr17:43067274-43071066 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000470026.5) at chr17:43093584-43125323 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt E7EWN5)
BRCA1 (ENST00000468300.5) at chr17:43044805-43125451 - Homo sapiens BRCA1 DNA repair associated (BRCA1), transcript variant 5, mRNA. (from RefSeq NM_007299)
BRCA1 (ENST00000461798.5) at chr17:43099831-43125370 - E3 ubiquitin-protein ligase that specifically mediates  the formation of 'Lys-6'-linked polyubiquitin chains and plays a  central role in DNA repair by facilitating cellular responses to  DNA damage. It is unclear whether it also mediates the formation  of other types of polyubiquitin chains. The E3 ubiquitin-protein  ligase activity is required for its tumor suppressor function. The  BRCA1-BARD1 heterodimer coordinates a diverse range of cellular  pathways such as DNA damage repair, ubiquitination and  transcriptional regulation to maintain genomic stability.  Regulates centrosomal microtubule nucleation. Required for normal  cell cycle progression from G2 to mitosis. Required for  appropriate cell cycle arrests after ionizing irradiation in both  the S-phase and the G2 phase of the cell cycle. Involved in  transcriptional regulation of P21 in response to DNA damage.  Required for FANCD2 targeting to sites of DNA damage. May function  as a transcriptional regulator. Inhibits lipid synthesis by  binding to inactive phosphorylated ACACA and preventing its  dephosphorylation. Contributes to homologous recombination repair  (HRR) via its direct interaction with PALB2, fine-tunes  recombinational repair partly through its modulatory role in the  PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA  breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1  activation and controls cell cycle G2/M checkpoints on DNA damage  via BRCA1-mediated ubiquitination of RBBP8. (from UniProt P38398)
BRCA1 (ENST00000461574.1) at chr17:43076537-43091824 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt H0Y850)
BRCA1 (ENST00000461221.5) at chr17:43045678-43125288 - Homo sapiens BRCA1 DNA repair associated (BRCA1), transcript variant 6, non-coding RNA. (from RefSeq NR_027676)
BRCA1 (ENST00000412061.3) at chr17:43093570-43095866 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000357654.8) at chr17:43044295-43125483 - Homo sapiens BRCA1 DNA repair associated (BRCA1), transcript variant 1, mRNA. (from RefSeq NM_007294)
BRCA1 (ENST00000354071.7) at chr17:43091098-43125315 - BRCA1, DNA repair associated (from HGNC BRCA1)
BRCA1 (ENST00000352993.7) at chr17:43044295-43125370 - E3 ubiquitin-protein ligase that specifically mediates  the formation of 'Lys-6'-linked polyubiquitin chains and plays a  central role in DNA repair by facilitating cellular responses to  DNA damage. It is unclear whether it also mediates the formation  of other types of polyubiquitin chains. The E3 ubiquitin-protein  ligase activity is required for its tumor suppressor function. The  BRCA1-BARD1 heterodimer coordinates a diverse range of cellular  pathways such as DNA damage repair, ubiquitination and  transcriptional regulation to maintain genomic stability.  Regulates centrosomal microtubule nucleation. Required for normal  cell cycle progression from G2 to mitosis. Required for  appropriate cell cycle arrests after ionizing irradiation in both  the S-phase and the G2 phase of the cell cycle. Involved in  transcriptional regulation of P21 in response to DNA damage.  Required for FANCD2 targeting to sites of DNA damage. May function  as a transcriptional regulator. Inhibits lipid synthesis by  binding to inactive phosphorylated ACACA and preventing its  dephosphorylation. Contributes to homologous recombination repair  (HRR) via its direct interaction with PALB2, fine-tunes  recombinational repair partly through its modulatory role in the  PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA  breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1  activation and controls cell cycle G2/M checkpoints on DNA damage  via BRCA1-mediated ubiquitination of RBBP8. (from UniProt P38398)
BRCC3P1 (ENST00000508559.1) at chr5:176308063-176309013 - BRCA1/BRCA2-containing complex subunit 3 pseudogene 1 (from HGNC BRCC3P1)
BARD1 (ENST00000650978.1) at chr2:214728571-214797117 - BRCA1 associated RING domain 1 (from HGNC BARD1)
BARD1 (ENST00000613706.5) at chr2:214728585-214809683 - BRCA1 associated RING domain 1 (from HGNC BARD1)
BARD1 (ENST00000613192.2) at chr2:214728676-214809683 - BRCA1 associated RING domain 1 (from HGNC BARD1)
BARD1 (ENST00000479904.1) at chr2:214796794-214809660 - BRCA1 associated RING domain 1 (from HGNC BARD1)
BARD1 (ENST00000471787.1) at chr2:214780897-214809670 - BRCA1 associated RING domain 1 (from HGNC BARD1)
BARD1 (ENST00000471590.5) at chr2:214728424-214731145 - BRCA1 associated RING domain 1 (from HGNC BARD1)
BARD1 (ENST00000465841.1) at chr2:214745712-214752478 - BRCA1 associated RING domain 1 (from HGNC BARD1)
BAP1 (ENST00000615113.1) at chr3:52401673-52402161 - BRCA1 associated protein 1 (from HGNC BAP1)
BAP1 (ENST00000490804.1) at chr3:52403703-52405653 - BRCA1 associated protein 1 (from HGNC BAP1)
BAP1 (ENST00000483984.5) at chr3:52406646-52409878 - BRCA1 associated protein 1 (from HGNC BAP1)
BAP1 (ENST00000471532.5) at chr3:52405811-52408047 - BRCA1 associated protein 1 (from HGNC BAP1)
BAP1 (ENST00000466093.1) at chr3:52402024-52403551 - BRCA1 associated protein 1 (from HGNC BAP1)
BRAT1 (ENST00000493232.5) at chr7:2537881-2544252 - BRCA1 associated ATM activator 1 (from HGNC BRAT1)
BRAT1 (ENST00000473879.1) at chr7:2538412-2541024 - BRCA1 associated ATM activator 1 (from HGNC BRAT1)
BRAT1 (ENST00000469750.5) at chr7:2537881-2555694 - BRCA1 associated ATM activator 1 (from HGNC BRAT1)
BRAT1 (ENST00000467558.5) at chr7:2537881-2554447 - BRCA1 associated ATM activator 1 (from HGNC BRAT1)
BRAP (ENST00000547043.1) at chr12:111644339-111673311 - BRCA1 associated protein (from HGNC BRAP)
BRIP1 (ENST00000583837.5) at chr17:61775878-61780277 - BRCA1 interacting protein C-terminal helicase 1 (from HGNC BRIP1)
BRCC3 (ENST00000630295.1) at chrX:155071528-155120150 - BRCA1/BRCA2-containing complex subunit 3 (from HGNC BRCC3)
BRCC3 (ENST00000620502.4) at chrX:155071528-155120150 - BRCA1/BRCA2-containing complex subunit 3 (from HGNC BRCC3)
BRCC3 (ENST00000411985.5) at chrX:155071518-155116183 - BRCA1/BRCA2-containing complex subunit 3 (from HGNC BRCC3)
BRCC3 (ENST00000399026.1) at chrX:155073411-155078930 - BRCA1/BRCA2-containing complex subunit 3 (from HGNC BRCC3)
BARD1 (ENST00000260947.9) at chr2:214725646-214809683 - Homo sapiens BRCA1 associated RING domain 1 (BARD1), transcript variant 8, non-coding RNA. (from RefSeq NR_104216)
BAP1 (ENST00000460680.6) at chr3:52401008-52410008 - Homo sapiens BRCA1 associated protein 1 (BAP1), mRNA. (from RefSeq NM_004656)
BRAT1 (ENST00000340611.9) at chr7:2537810-2555524 - Homo sapiens BRCA1 associated ATM activator 1 (BRAT1), transcript variant 4, non-coding RNA. (from RefSeq NR_146879)
BRAP (ENST00000419234.9) at chr12:111642146-111685956 - Homo sapiens BRCA1 associated protein (BRAP), mRNA. (from RefSeq NM_006768)
NBR2 (ENST00000657841.1) at chr17:43125551-43153649 - neighbor of BRCA1 gene 2 (non-protein coding) (from HGNC NBR2)
BRIP1 (ENST00000259008.6) at chr17:61681266-61863521 - Homo sapiens BRCA1 interacting protein C-terminal helicase 1 (BRIP1), mRNA. (from RefSeq NM_032043)
BARD1 (ENST00000619009.5) at chr2:214728553-214809597 - Homo sapiens BRCA1 associated RING domain 1 (BARD1), transcript variant 5, mRNA. (from RefSeq NM_001282549)
BARD1 (ENST00000617164.5) at chr2:214728553-214809642 - Homo sapiens BRCA1 associated RING domain 1 (BARD1), transcript variant 2, mRNA. (from RefSeq NM_001282543)
BARD1 (ENST00000613374.5) at chr2:214728562-214809642 - Homo sapiens BRCA1 associated RING domain 1 (BARD1), transcript variant 4, mRNA. (from RefSeq NM_001282548)
BABAM2 (ENST00000604932.1) at chr2:27894620-28025488 - BRISC and BRCA1 A complex member 2 (from HGNC BABAM2)
BABAM2 (ENST00000603461.1) at chr2:27890784-28025488 - BRISC and BRCA1 A complex member 2 (from HGNC BABAM2)
BABAM2 (ENST00000496951.1) at chr2:27890787-27930361 - BRISC and BRCA1 A complex member 2 (from HGNC BABAM2)
BABAM2 (ENST00000492702.1) at chr2:27890763-27895068 - BRISC and BRCA1 A complex member 2 (from HGNC BABAM2)
BARD1 (ENST00000455743.5) at chr2:214728704-214809673 - Homo sapiens BRCA1 associated RING domain 1 (BARD1), transcript variant 6, non-coding RNA. (from RefSeq NR_104212)
BARD1 (ENST00000421162.2) at chr2:214728675-214809597 - Homo sapiens BRCA1 associated RING domain 1 (BARD1), transcript variant 3, mRNA. (from RefSeq NM_001282545)
ABRAXAS1 (ENST00000611288.4) at chr4:83463723-83470333 - abraxas 1, BRCA1 A complex subunit (from HGNC ABRAXAS1)
ABRAXAS1 (ENST00000505489.5) at chr4:83467454-83523348 - abraxas 1, BRCA1 A complex subunit (from HGNC ABRAXAS1)
ABRAXAS1 (ENST00000504777.1) at chr4:83462075-83469901 - abraxas 1, BRCA1 A complex subunit (from HGNC ABRAXAS1)
ABRAXAS1 (ENST00000503217.2) at chr4:83470274-83485100 - abraxas 1, BRCA1 A complex subunit (from HGNC ABRAXAS1)
NBR2 (ENST00000356906.7) at chr17:43125640-43140333 - neighbor of BRCA1 gene 2 (non-protein coding) (from HGNC NBR2)
BABAM1 (ENST00000602066.5) at chr19:17268685-17276602 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000601938.5) at chr19:17268559-17276550 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000601436.5) at chr19:17267474-17275825 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000601232.1) at chr19:17276814-17279342 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000601171.5) at chr19:17267457-17274173 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000599474.5) at chr19:17267437-17276525 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000599057.5) at chr19:17267443-17274185 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000598567.1) at chr19:17268997-17279339 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000598382.1) at chr19:17276428-17278984 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000596335.5) at chr19:17267471-17276556 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000595393.5) at chr19:17267443-17277523 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000594247.5) at chr19:17267376-17281249 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BABAM1 (ENST00000448635.2) at chr19:17267478-17276555 - BRISC and BRCA1 A complex member 1 (from HGNC BABAM1)
BRCC3 (ENST00000369462.5) at chrX:155071503-155123074 - Homo sapiens BRCA1/BRCA2-containing complex subunit 3 (BRCC3), transcript variant 1, mRNA. (from RefSeq NM_024332)
BRCC3 (ENST00000340647.8) at chrX:155071420-155121318 - Homo sapiens BRCA1/BRCA2-containing complex subunit 3 (BRCC3), transcript variant 3, mRNA. (from RefSeq NM_001242640)
BRCC3 (ENST00000330045.11) at chrX:155071431-155122727 - Homo sapiens BRCA1/BRCA2-containing complex subunit 3 (BRCC3), transcript variant 2, mRNA. (from RefSeq NM_001018055)
BABAM1 (ENST00000601043.5) at chr19:17267443-17279337 - Component of the BRCA1-A complex, a complex that  specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A  and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1  heterodimer to sites of DNA damage at double-strand breaks (DSBs).  The BRCA1-A complex also possesses deubiquitinase activity that  specifically removes 'Lys-63'-linked ubiquitin on histones H2A and  H2AX. In the BRCA1-A complex, it is required for the complex  integrity and its localization at DSBs. Probably also plays a role  as a component of the BRISC complex, a multiprotein complex that  specifically cleaves 'Lys-63'-linked ubiquitin. In these 2  complexes, it is probably required to maintain the stability of  BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity  mediated by BRCC3/BRCC36 component. (from UniProt Q9NWV8)
BABAM2 (ENST00000379624.5) at chr2:27890750-28338901 - Homo sapiens BRISC and BRCA1 A complex member 2 (BABAM2), transcript variant 11, non-coding RNA. (from RefSeq NR_137437)
ABRAXAS1 (ENST00000321945.12) at chr4:83459517-83485100 - Homo sapiens abraxas 1, BRCA1 A complex subunit (ABRAXAS1), transcript variant 1, mRNA. (from RefSeq NM_139076)
BABAM1 (ENST00000359435.8) at chr19:17267386-17279337 - Homo sapiens BRISC and BRCA1 A complex member 1 (BABAM1), transcript variant 3, mRNA. (from RefSeq NM_001288756)
BABAM2 (ENST00000379632.6) at chr2:27890793-28338901 - Homo sapiens BRISC and BRCA1 A complex member 2 (BABAM2), transcript variant 4, mRNA. (from RefSeq NM_199193)
BABAM2 (ENST00000361704.6) at chr2:27890793-28338901 - Homo sapiens BRISC and BRCA1 A complex member 2 (BABAM2), transcript variant 12, non-coding RNA. (from RefSeq NR_137438)
BABAM2 (ENST00000344773.6) at chr2:27890729-28338901 - Homo sapiens BRISC and BRCA1 A complex member 2 (BABAM2), transcript variant 14, non-coding RNA. (from RefSeq NR_137440)
BABAM2 (ENST00000342045.6) at chr2:27890792-28338901 - Homo sapiens BRISC and BRCA1 A complex member 2 (BABAM2), transcript variant 2, mRNA. (from RefSeq NM_199194)
ABRAXAS1 (ENST00000506553.5) at chr4:83462009-83485555 - Homo sapiens abraxas 1, BRCA1 A complex subunit (ABRAXAS1), transcript variant 2, mRNA. (from RefSeq NM_001345962)
NBR2 (ENST00000467245.5) at chr17:43125644-43153671 - Homo sapiens neighbor of BRCA1 lncRNA 2 (NBR2), transcript variant 2, long non-coding RNA. (from RefSeq NR_138145)
NBR2 (ENST00000460115.5) at chr17:43125610-43145113 - Homo sapiens neighbor of BRCA1 lncRNA 2 (NBR2), transcript variant 1, long non-coding RNA. (from RefSeq NR_003108)
BABAM1 (ENST00000598188.6) at chr19:17267443-17279337 - Homo sapiens BRISC and BRCA1 A complex member 1 (BABAM1), transcript variant 2, mRNA. (from RefSeq NM_014173)
BABAM1 (ENST00000447614.6) at chr19:17267376-17279048 - Homo sapiens BRISC and BRCA1 A complex member 1 (BABAM1), transcript variant 4, mRNA. (from RefSeq NM_001288757)
BARD1 (ENST00000620057.4) at chr2:214728677-214809642 - Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1  heterodimer specifically mediates the formation of 'Lys-6'-linked  polyubiquitin chains and coordinates a diverse range of cellular  pathways such as DNA damage repair, ubiquitination and  transcriptional regulation to maintain genomic stability. Plays a  central role in the control of the cell cycle in response to DNA  damage. Acts by mediating ubiquitin E3 ligase activity that is  required for its tumor suppressor function. Also forms a  heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and  RNAP II stability by inhibiting pre-mRNA 3' cleavage. (from UniProt Q99728)
UIMC1 (ENST00000510698.2) at chr5:176905066-176970793 - Ubiquitin-binding protein that specifically recognizes  and binds 'Lys-63'-linked ubiquitin. Plays a central role in the  BRCA1-A complex by specifically binding 'Lys-63'-linked  ubiquitinated histones H2A and H2AX at DNA lesions sites, leading  to target the BRCA1-BARD1 heterodimer to sites of DNA damage at  double-strand breaks (DSBs). The BRCA1-A complex also possesses  deubiquitinase activity that specifically removes 'Lys-63'-linked  ubiquitin on histones H2A and H2AX. Also weakly binds  monoubiquitin but with much less affinity than 'Lys-63'-linked  ubiquitin. May interact with monoubiquitinated histones H2A and  H2B; the relevance of such results is however unclear in vivo.  Does not bind Lys-48'-linked ubiquitin. May indirectly act as a  transcriptional repressor by inhibiting the interaction of NR6A1  with the corepressor NCOR1. (from UniProt Q96RL1)
BRCC3 (ENST00000369459.6) at chrX:155071499-155123072 - Metalloprotease that specifically cleaves 'Lys-63'-  linked polyubiquitin chains. Does not have activity toward 'Lys-  48'-linked polyubiquitin chains. Component of the BRCA1-A complex,  a complex that specifically recognizes 'Lys-63'-linked  ubiquitinated histones H2A and H2AX at DNA lesions sites, leading  to target the BRCA1-BARD1 heterodimer to sites of DNA damage at  double-strand breaks (DSBs). In the BRCA1-A complex, it  specifically removes 'Lys-63'-linked ubiquitin on histones H2A and  H2AX, antagonizing the RNF8-dependent ubiquitination at double-  strand breaks (DSBs). Catalytic subunit of the BRISC complex, a  multiprotein complex that specifically cleaves 'Lys-63'-linked  ubiquitin in various substrates. Mediates the specific 'Lys-63'-  specific deubiquitination associated with the COP9 signalosome  complex (CSN), via the interaction of the BRISC complex with the  CSN complex. (from UniProt P46736)
BRCA2 (ENST00000544455.5) at chr13:32315480-32399668 - Homo sapiens BRCA2 DNA repair associated (BRCA2), mRNA. (from RefSeq NM_000059)
PHF11 (ENST00000357596.7) at chr13:49496392-49528981 - Positive regulator of Th1-type cytokine gene expression. (from UniProt Q9UIL8)
UBXN1 (ENST00000301935.9) at chr11:62676498-62679090 - Homo sapiens UBX domain protein 1 (UBXN1), transcript variant 2, mRNA. (from RefSeq NM_001286077)
UBXN1 (ENST00000294119.6) at chr11:62676498-62679055 - Homo sapiens UBX domain protein 1 (UBXN1), transcript variant 1, mRNA. (from RefSeq NM_015853)
ZCCHC8 (ENST00000536306.5) at chr12:122472870-122499325 - May be involved in pre-mRNA splicing. (from UniProt Q6NZY4)
PES1 (ENST00000405677.5) at chr22:30576632-30606988 - Homo sapiens pescadillo ribosomal biogenesis factor 1 (PES1), transcript variant 4, mRNA. (from RefSeq NM_001282328)
PES1 (ENST00000402281.5) at chr22:30576628-30607083 - Homo sapiens pescadillo ribosomal biogenesis factor 1 (PES1), transcript variant 2, mRNA. (from RefSeq NM_001282327)
PES1 (ENST00000354694.12) at chr22:30576625-30591910 - Homo sapiens pescadillo ribosomal biogenesis factor 1 (PES1), transcript variant 1, mRNA. (from RefSeq NM_014303)
PES1 (ENST00000335214.8) at chr22:30576835-30591858 - Homo sapiens pescadillo ribosomal biogenesis factor 1 (PES1), transcript variant 3, mRNA. (from RefSeq NM_001243225)
ZNF350 (ENST00000243644.9) at chr19:51964340-51986840 - Homo sapiens zinc finger protein 350 (ZNF350), mRNA. (from RefSeq NM_021632)
UIMC1 (ENST00000506128.5) at chr5:176905050-177006581 - Homo sapiens ubiquitin interaction motif containing 1 (UIMC1), transcript variant 4, mRNA. (from RefSeq NM_001317961)
UIMC1 (ENST00000377227.8) at chr5:176905005-177006408 - Homo sapiens ubiquitin interaction motif containing 1 (UIMC1), transcript variant 2, mRNA. (from RefSeq NM_016290)
UIMC1 (ENST00000511320.6) at chr5:176905006-177006779 - Homo sapiens ubiquitin interaction motif containing 1 (UIMC1), transcript variant 6, non-coding RNA. (from RefSeq NR_146150)
BRIP1 (ENST00000577598.5) at chr17:61684772-61861539 - DNA-dependent ATPase and 5' to 3' DNA helicase required  for the maintenance of chromosomal stability. Acts late in the  Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in  the repair of DNA double-strand breaks by homologous recombination  in a manner that depends on its association with BRCA1. (from UniProt Q9BX63)
MDC1 (ENST00000427406.6) at chr6_GL000250v2_alt:2029312-2047393 - Homo sapiens mediator of DNA damage checkpoint 1 (MDC1), mRNA. (from RefSeq NM_014641)
MDC1 (ENST00000420019.6) at chr6_GL000251v2_alt:2179547-2197629 - Homo sapiens mediator of DNA damage checkpoint 1 (MDC1), mRNA. (from RefSeq NM_014641)
MDC1 (ENST00000440369.6) at chr6_GL000253v2_alt:2010059-2028140 - Homo sapiens mediator of DNA damage checkpoint 1 (MDC1), mRNA. (from RefSeq NM_014641)
MDC1 (ENST00000449153.6) at chr6_GL000254v2_alt:2043883-2061964 - Homo sapiens mediator of DNA damage checkpoint 1 (MDC1), mRNA. (from RefSeq NM_014641)
MDC1 (ENST00000383566.8) at chr6_GL000255v2_alt:1954920-1973001 - Homo sapiens mediator of DNA damage checkpoint 1 (MDC1), mRNA. (from RefSeq NM_014641)
MDC1 (ENST00000435664.6) at chr6_GL000256v2_alt:2000593-2018675 - Homo sapiens mediator of DNA damage checkpoint 1 (MDC1), mRNA. (from RefSeq NM_014641)
BABAM2 (ENST00000436924.5) at chr2:27889941-28025385 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt C9J2G0)
BABAM2 (ENST00000379629.7) at chr2:27894545-28233315 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt F8W733)
MDC1 (ENST00000420320.6) at chr6_GL000252v2_alt:1955659-1973740 - Homo sapiens mediator of DNA damage checkpoint 1 (MDC1), mRNA. (from RefSeq NM_014641)
MDC1 (ENST00000376406.8) at chr6:30699807-30717281 - Homo sapiens mediator of DNA damage checkpoint 1 (MDC1), mRNA. (from RefSeq NM_014641)
OLA1 (ENST00000344357.9) at chr2:174075008-174248599 - Homo sapiens Obg like ATPase 1 (OLA1), transcript variant 2, mRNA. (from RefSeq NM_001011708)
UIMC1 (ENST00000512031.5) at chr5:176905053-177006715 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt D6RCQ3)
UIMC1 (ENST00000509236.5) at chr5:176969283-177022602 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt D6RC40)
UIMC1 (ENST00000507513.1) at chr5:176970832-177006714 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt D6RDZ5)
OLA1 (ENST00000284719.8) at chr2:174072447-174248532 - Homo sapiens Obg like ATPase 1 (OLA1), transcript variant 1, mRNA. (from RefSeq NM_013341)
BRCC3 (ENST00000399042.4) at chrX:155071528-155120150 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt H9KVA9)
BABAM1 (ENST00000595632.5) at chr19:17267502-17279172 - The sequence shown here is derived from an Ensembl  automatic analysis pipeline and should be considered as  preliminary data. (from UniProt J3KQS6)
RNF169 (ENST00000299563.5) at chr11:74748849-74842413 - Homo sapiens ring finger protein 169 (RNF169), mRNA. (from RefSeq NM_001098638)
HMMR (ENST00000432118.6) at chr5:163460634-163491238 - Homo sapiens hyaluronan mediated motility receptor (HMMR), transcript variant 4, mRNA. (from RefSeq NM_001142557)
HMMR (ENST00000358715.3) at chr5:163460657-163491941 - Homo sapiens hyaluronan mediated motility receptor (HMMR), transcript variant 2, mRNA. (from RefSeq NM_012484)
HMMR (ENST00000353866.7) at chr5:163460366-163491579 - Homo sapiens hyaluronan mediated motility receptor (HMMR), transcript variant 3, mRNA. (from RefSeq NM_012485)
HMMR (ENST00000393915.9) at chr5:163460632-163491941 - Homo sapiens hyaluronan mediated motility receptor (HMMR), transcript variant 1, mRNA. (from RefSeq NM_001142556)
ATM (ENST00000639240.1) at chr11:108223174-108229363 - Homo sapiens ATM serine/threonine kinase (ATM), transcript variant 3, mRNA. (from RefSeq NM_001351835)
ATM (ENST00000526567.5) at chr11:108223529-108229364 - Homo sapiens ATM serine/threonine kinase (ATM), transcript variant 4, mRNA. (from RefSeq NM_001351836)
ATM (ENST00000278616.8) at chr11:108222832-108369099 - Homo sapiens ATM serine/threonine kinase (ATM), transcript variant 2, mRNA. (from RefSeq NM_000051)
RBBP8 (ENST00000399725.6) at chr18:22933841-23026486 - Homo sapiens RB binding protein 8, endonuclease (RBBP8), transcript variant 3, mRNA. (from RefSeq NM_203292)
RBBP8 (ENST00000399722.6) at chr18:22933826-23026488 - Homo sapiens RB binding protein 8, endonuclease (RBBP8), transcript variant 2, mRNA. (from RefSeq NM_203291)
RBBP8 (ENST00000327155.10) at chr18:22933328-23026486 - Homo sapiens RB binding protein 8, endonuclease (RBBP8), transcript variant 1, mRNA. (from RefSeq NM_002894)
ATM (ENST00000452508.6) at chr11:108223116-108369102 - Homo sapiens ATM serine/threonine kinase (ATM), transcript variant 1, mRNA. (from RefSeq NM_001351834)
AURKA (ENST00000371356.6) at chr20:56369390-56392196 - Mitotic serine/threonine kinases that contributes to the  regulation of cell cycle progression. Associates with the  centrosome and the spindle microtubules during mitosis and plays a  critical role in various mitotic events including the  establishment of mitotic spindle, centrosome duplication,  centrosome separation as well as maturation, chromosomal  alignment, spindle assembly checkpoint, and cytokinesis. Required  for initial activation of CDK1 at centrosomes. Phosphorylates  numerous target proteins, including ARHGEF2, BORA, BRCA1, CDC25B,  DLGP5, HDAC6, KIF2A, LATS2, NDEL1, PARD3, PPP1R2, PLK1, RASSF1,  TACC3, p53/TP53 and TPX2. Regulates KIF2A tubulin depolymerase  activity. Required for normal axon formation. Plays a role in  microtubule remodeling during neurite extension. Important for  microtubule formation and/or stabilization. Also acts as a key  regulatory component of the p53/TP53 pathway, and particularly the  checkpoint-response pathways critical for oncogenic transformation  of cells, by phosphorylating and stabilizating p53/TP53.  Phosphorylates its own inhibitors, the protein phosphatase type 1  (PP1) isoforms, to inhibit their activity. Necessary for proper  cilia disassembly prior to mitosis. (from UniProt O14965)
ABRAXAS2 (ENST00000298492.6) at chr10:124801819-124836667 - Homo sapiens abraxas 2, BRISC complex subunit (ABRAXAS2), mRNA. (from RefSeq NM_032182)
NUFIP1 (ENST00000379161.5) at chr13:44939249-44989471 - Homo sapiens nuclear FMR1 interacting protein 1 (NUFIP1), mRNA. (from RefSeq NM_012345)
RNF8 (ENST00000229866.10) at chr6:37354015-37391168 - E3 ubiquitin-protein ligase that plays a key role in DNA  damage signaling via 2 distinct roles: by mediating the 'Lys-63'-  linked ubiquitination of histones H2A and H2AX and promoting the  recruitment of DNA repair proteins at double-strand breaks (DSBs)  sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove  target proteins from DNA damage sites. Following DNA DSBs, it is  recruited to the sites of damage by ATM-phosphorylated MDC1 and  catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and  H2AX, thereby promoting the formation of TP53BP1 and BRCA1  ionizing radiation-induced foci (IRIF). Also controls the  recruitment of UIMC1-BRCC3 (RAP80-BRCC36) and PAXIP1/PTIP to DNA  damage sites. Also recruited at DNA interstrand cross-links (ICLs)  sites and catalyzes 'Lys-63'-linked ubiquitination of histones H2A  and H2AX, leading to recruitment of FAAP20/C1orf86 and Fanconi  anemia (FA) complex, followed by interstrand cross-link repair.  H2A ubiquitination also mediates the ATM-dependent transcriptional  silencing at regions flanking DSBs in cis, a mechanism to avoid  collision between transcription and repair intermediates. Promotes  the formation of 'Lys-63'-linked polyubiquitin chains via  interactions with the specific ubiquitin-conjugating UBE2N/UBC13  and ubiquitinates non-histone substrates such as PCNA. Substrates  that are polyubiquitinated at 'Lys-63' are usually not targeted  for degradation. Also catalyzes the formation of 'Lys-48'-linked  polyubiquitin chains via interaction with the ubiquitin-  conjugating UBE2L6/UBCH8, leading to degradation of substrate  proteins such as CHEK2, JMJD2A/KDM4A and KU80/XRCC5: it is still  unclear how the preference toward 'Lys-48'- versus 'Lys-63'-linked  ubiquitination is regulated but it could be due to RNF8 ability to  interact with specific E2 specific ligases. For instance,  interaction with phosphorylated HERC2 promotes the association  between RNF8 and UBE2N/UBC13 and favors the specific formation of  'Lys-63'-linked ubiquitin chains. Promotes non-homologous end  joining (NHEJ) by promoting the 'Lys-48'-linked ubiquitination and  degradation the of KU80/XRCC5. Following DNA damage, mediates the  ubiquitination and degradation of JMJD2A/KDM4A in collaboration  with RNF168, leading to unmask H4K20me2 mark and promote the  recruitment of TP53BP1 at DNA damage sites. In addition to its  function in damage signaling, also plays a role in higher-order  chromatin structure by mediating extensive chromatin  decondensation. Involved in the activation of ATM by promoting  histone H2B ubiquitination, which indirectly triggers histone H4  'Lys-16' acetylation (H4K16ac), establishing a chromatin  environment that promotes efficient activation of ATM kinase.  Required in the testis, where it plays a role in the replacement  of histones during spermatogenesis. At uncapped telomeres,  promotes the joining of deprotected chromosome ends by inducing  H2A ubiquitination and TP53BP1 recruitment, suggesting that it may  enhance cancer development by aggraving telomere-induced genome  instability in case of telomeric crisis. Promotes the assembly of  RAD51 at DNA DSBs in the absence of BRCA1 and TP53BP1 Also  involved in class switch recombination in immune system, via its  role in regulation of DSBs repair. May be required for proper exit  from mitosis after spindle checkpoint activation and may regulate  cytokinesis. May play a role in the regulation of RXRA-mediated  transcriptional activity. Not involved in RXRA ubiquitination by  UBE2E2. (from UniProt O76064)
PHF11 (ENST00000488958.5) at chr13:49497113-49528976 - Homo sapiens PHD finger protein 11 (PHF11), transcript variant 2, mRNA. (from RefSeq NM_001040444)
RND2 (ENST00000587250.4) at chr17:43025231-43032041 - Homo sapiens Rho family GTPase 2 (RND2), mRNA. (from RefSeq NM_005440)
RBBP7 (ENST00000380087.6) at chrX:16844341-16870414 - Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2, mRNA. (from RefSeq NM_002893)
RBBP7 (ENST00000380084.8) at chrX:16844654-16869886 - Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 1, mRNA. (from RefSeq NM_001198719)
PHF11 (ENST00000378319.8) at chr13:49495953-49528976 - Homo sapiens PHD finger protein 11 (PHF11), transcript variant 1, mRNA. (from RefSeq NM_001040443)
NBR1 (ENST00000542611.5) at chr17:43171202-43209993 - Homo sapiens NBR1 autophagy cargo receptor (NBR1), transcript variant 5, mRNA. (from RefSeq NM_001291572)
RAD51 (ENST00000645673.2) at chr15:40695174-40732340 - Homo sapiens RAD51 recombinase (RAD51), transcript variant 2, mRNA. (from RefSeq NM_133487)
RAD51 (ENST00000423169.6) at chr15:40695129-40731592 - Homo sapiens RAD51 recombinase (RAD51), transcript variant 3, mRNA. (from RefSeq NM_001164270)
PCLAF (ENST00000380258.6) at chr15:64365365-64381444 - Homo sapiens PCNA clamp associated factor (PCLAF), transcript variant 2, mRNA. (from RefSeq NM_001029989)
PCLAF (ENST00000300035.9) at chr15:64364304-64381441 - Homo sapiens PCNA clamp associated factor (PCLAF), transcript variant 1, mRNA. (from RefSeq NM_014736)
RAD51 (ENST00000267868.8) at chr15:40695174-40732340 - Homo sapiens RAD51 recombinase (RAD51), transcript variant 1, mRNA. (from RefSeq NM_002875)
NBR1 (ENST00000589872.1) at chr17:43171243-43209857 - Homo sapiens NBR1 autophagy cargo receptor (NBR1), transcript variant 4, mRNA. (from RefSeq NM_001291571)
NBR1 (ENST00000341165.10) at chr17:43170481-43211689 - Homo sapiens NBR1 autophagy cargo receptor (NBR1), transcript variant 3, mRNA. (from RefSeq NM_031862)
NBR1 (ENST00000590996.6) at chr17:43171214-43211688 - Homo sapiens NBR1 autophagy cargo receptor (NBR1), transcript variant 1, mRNA. (from RefSeq NM_005899)
IFI16 (ENST00000448393.6) at chr1:159014681-159055124 - Binds double-stranded DNA. Binds preferentially to  supercoiled DNA and cruciform DNA structures. Seems to be involved  in transcriptional regulation. May function as a transcriptional  repressor. Could have a role in the regulation of hematopoietic  differentiation through activation of unknown target genes.  Controls cellular proliferation by modulating the functions of  cell cycle regulatory factors including p53/TP53 and the  retinoblastoma protein. May be involved in TP53-mediated  transcriptional activation by enhancing TP53 sequence-specific DNA  binding and modulating TP53 phosphorylation status. Seems to be  involved in energy-level-dependent activation of the ATM/  AMPK/TP53 pathway coupled to regulation of autophagy. May be  involved in regulation of TP53-mediated cell death also involving  BRCA1. May be involved in the senescence of prostate epithelial  cells. Involved in innate immune response by recognizing viral  dsDNA in the cytosol and probably in the nucleus. After binding to  viral DNA in the cytoplasm recruits TMEM173/STING and mediates the  induction of IFN-beta. Has anti-inflammatory activity and inhibits  the activation of the AIM2 inflammasome, probably via association  with AIM2. Proposed to bind viral DNA in the nucleus, such as of  Kaposi's sarcoma-associated herpesvirus, and to induce the  formation of nuclear caspase-1-activating inflammasome formation  via association with PYCARD. Inhibits replication of herpesviruses  such as human cytomegalovirus (HCMV) probably by interfering with  promoter recruitment of members of the Sp1 family of transcription  factors. (from UniProt Q16666)
IFI16 (ENST00000368132.7) at chr1:159009918-159055151 - Binds double-stranded DNA. Binds preferentially to  supercoiled DNA and cruciform DNA structures. Seems to be involved  in transcriptional regulation. May function as a transcriptional  repressor. Could have a role in the regulation of hematopoietic  differentiation through activation of unknown target genes.  Controls cellular proliferation by modulating the functions of  cell cycle regulatory factors including p53/TP53 and the  retinoblastoma protein. May be involved in TP53-mediated  transcriptional activation by enhancing TP53 sequence-specific DNA  binding and modulating TP53 phosphorylation status. Seems to be  involved in energy-level-dependent activation of the ATM/  AMPK/TP53 pathway coupled to regulation of autophagy. May be  involved in regulation of TP53-mediated cell death also involving  BRCA1. May be involved in the senescence of prostate epithelial  cells. Involved in innate immune response by recognizing viral  dsDNA in the cytosol and probably in the nucleus. After binding to  viral DNA in the cytoplasm recruits TMEM173/STING and mediates the  induction of IFN-beta. Has anti-inflammatory activity and inhibits  the activation of the AIM2 inflammasome, probably via association  with AIM2. Proposed to bind viral DNA in the nucleus, such as of  Kaposi's sarcoma-associated herpesvirus, and to induce the  formation of nuclear caspase-1-activating inflammasome formation  via association with PYCARD. Inhibits replication of herpesviruses  such as human cytomegalovirus (HCMV) probably by interfering with  promoter recruitment of members of the Sp1 family of transcription  factors. (from UniProt Q16666)
SMC1A (ENST00000375340.10) at chrX:53374149-53422728 - Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 2, mRNA. (from RefSeq NM_001281463)
SMARCA4 (ENST00000646693.1) at chr19:10960932-11062279 - Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 1, mRNA. (from RefSeq NM_001128849)
CLSPN (ENST00000251195.9) at chr1:35720218-35769967 - Homo sapiens claspin (CLSPN), transcript variant 3, mRNA. (from RefSeq NM_001330490)
CLSPN (ENST00000373220.7) at chr1:35736405-35769928 - Homo sapiens claspin (CLSPN), transcript variant 2, mRNA. (from RefSeq NM_001190481)
CTCFL (ENST00000422109.6) at chr20:57499554-57524867 - Testis-specific DNA binding protein responsible for  insulator function, nuclear architecture and transcriptional  control, which probably acts by recruiting epigenetic chromatin  modifiers. Plays a key role in gene imprinting in male germline,  by participating in the establishment of differential methylation  at the IGF2/H19 imprinted control region (ICR). Directly binds the  unmethylated H19 ICR and recruits the PRMT7 methyltransferase,  leading to methylate histone H4 'Arg-3' to form H4R3sme2. This  probably leads to recruit de novo DNA methyltransferases at these  sites (By similarity). Seems to act as tumor suppressor. In  association with DNMT1 and DNMT3B, involved in activation of BAG1  gene expression by binding to its promoter. Required for  dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters. (from UniProt Q8NI51)
CTCFL (ENST00000243914.7) at chr20:57497168-57525209 - Testis-specific DNA binding protein responsible for  insulator function, nuclear architecture and transcriptional  control, which probably acts by recruiting epigenetic chromatin  modifiers. Plays a key role in gene imprinting in male germline,  by participating in the establishment of differential methylation  at the IGF2/H19 imprinted control region (ICR). Directly binds the  unmethylated H19 ICR and recruits the PRMT7 methyltransferase,  leading to methylate histone H4 'Arg-3' to form H4R3sme2. This  probably leads to recruit de novo DNA methyltransferases at these  sites (By similarity). Seems to act as tumor suppressor. In  association with DNMT1 and DNMT3B, involved in activation of BAG1  gene expression by binding to its promoter. Required for  dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters. (from UniProt Q8NI51)
CLSPN (ENST00000318121.8) at chr1:35732112-35769978 - Homo sapiens claspin (CLSPN), transcript variant 1, mRNA. (from RefSeq NM_022111)
SMC1A (ENST00000322213.8) at chrX:53374149-53422728 - Homo sapiens structural maintenance of chromosomes 1A (SMC1A), transcript variant 1, mRNA. (from RefSeq NM_006306)
DUSP3 (ENST00000226004.8) at chr17:43766125-43778977 - Homo sapiens dual specificity phosphatase 3 (DUSP3), mRNA. (from RefSeq NM_004090)
SMARCA4 (ENST00000647230.1) at chr19:10960957-11062276 - Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 6, mRNA. (from RefSeq NM_001128847)
SMARCA4 (ENST00000645460.1) at chr19:10961043-11062271 - Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 7, mRNA. (from RefSeq NM_001128848)
SMARCA4 (ENST00000643296.1) at chr19:10960957-11062276 - Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 4, mRNA. (from RefSeq NM_001128845)
SMARCA4 (ENST00000589677.5) at chr19:10961105-11061816 - Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 5, mRNA. (from RefSeq NM_001128846)
SMARCA4 (ENST00000429416.8) at chr19:10961001-11062256 - Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 2, mRNA. (from RefSeq NM_001128844)
SMARCA4 (ENST00000344626.9) at chr19:10960825-11062282 - Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 3, mRNA. (from RefSeq NM_003072)
UBE2D3 (ENST00000349311.12) at chr4:102797264-102827849 - Accepts ubiquitin from the E1 complex and catalyzes its  covalent attachment to other proteins. In vitro catalyzes 'Lys-  11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates  with the E2 CDC34 and the SCF(FBXW11) E3 ligase complex for the  polyubiquitination of NFKBIA leading to its subsequent proteasomal  degradation. Acts as an initiator E2, priming the phosphorylated  NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a  monoubiquitin. Ubiquitin chain elongation is then performed by  CDC34, building ubiquitin chains from the UBE2D3-primed NFKBIA-  linked ubiquitin. Acts also as an initiator E2, in conjunction  with RNF8, for the priming of PCNA. Monoubiquitination of PCNA,  and its subsequent polyubiquitination, are essential events in the  operation of the DNA damage tolerance (DDT) pathway that is  activated after DNA damage caused by UV or chemical agents during  S-phase. Associates with the BRCA1/BARD1 E3 ligase complex to  perform ubiquitination at DNA damage sites following ionizing  radiation leading to DNA repair. Targets DAPK3 for ubiquitination  which influences promyelocytic leukemia protein nuclear body (PML-  NB) formation in the nucleus. In conjunction with the MDM2 and  TOPORS E3 ligases, functions ubiquitination of p53/TP53. Supports  NRDP1-mediated ubiquitination and degradation of ERBB3 and of  BRUCE which triggers apoptosis. In conjunction with the CBL E3  ligase, targets EGFR for polyubiquitination at the plasma membrane  as well as during its internalization and transport on endosomes.  In conjunction with the STUB1 E3 quality control E3 ligase,  ubiquitinates unfolded proteins to catalyze their immediate  destruction (By similarity). (from UniProt P61077)
UBE2D3 (ENST00000321805.11) at chr4:102797235-102827553 - Accepts ubiquitin from the E1 complex and catalyzes its  covalent attachment to other proteins. In vitro catalyzes 'Lys-  11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates  with the E2 CDC34 and the SCF(FBXW11) E3 ligase complex for the  polyubiquitination of NFKBIA leading to its subsequent proteasomal  degradation. Acts as an initiator E2, priming the phosphorylated  NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a  monoubiquitin. Ubiquitin chain elongation is then performed by  CDC34, building ubiquitin chains from the UBE2D3-primed NFKBIA-  linked ubiquitin. Acts also as an initiator E2, in conjunction  with RNF8, for the priming of PCNA. Monoubiquitination of PCNA,  and its subsequent polyubiquitination, are essential events in the  operation of the DNA damage tolerance (DDT) pathway that is  activated after DNA damage caused by UV or chemical agents during  S-phase. Associates with the BRCA1/BARD1 E3 ligase complex to  perform ubiquitination at DNA damage sites following ionizing  radiation leading to DNA repair. Targets DAPK3 for ubiquitination  which influences promyelocytic leukemia protein nuclear body (PML-  NB) formation in the nucleus. In conjunction with the MDM2 and  TOPORS E3 ligases, functions ubiquitination of p53/TP53. Supports  NRDP1-mediated ubiquitination and degradation of ERBB3 and of  BRUCE which triggers apoptosis. In conjunction with the CBL E3  ligase, targets EGFR for polyubiquitination at the plasma membrane  as well as during its internalization and transport on endosomes.  In conjunction with the STUB1 E3 quality control E3 ligase,  ubiquitinates unfolded proteins to catalyze their immediate  destruction (By similarity). (from UniProt P61077)
RAD51 (ENST00000557850.5) at chr15:40695172-40731590 - Participates in a common DNA damage response pathway  associated with the activation of homologous recombination and  double-strand break repair. Binds to single and double stranded  DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex  DNA and forms helical nucleoprotein filaments. Plays a role in  regulating mitochondrial DNA copy number under conditions of  oxidative stress in the presence of RAD51C and XRCC3. (from UniProt Q06609)
ZCCHC8 (ENST00000633063.2) at chr12:122472899-122501073 - Homo sapiens zinc finger CCHC-type containing 8 (ZCCHC8), transcript variant 1, mRNA. (from RefSeq NM_017612)
BLM (ENST00000355112.8) at chr15:90717346-90816166 - Homo sapiens BLM RecQ like helicase (BLM), transcript variant 4, mRNA. (from RefSeq NM_001287248)
NELFB (ENST00000634710.2) at chr9:137255366-137272928 - Essential component of the NELF complex, a complex that  negatively regulates the elongation of transcription by RNA  polymerase II. The NELF complex, which acts via an association  with the DSIF complex and causes transcriptional pausing, is  counteracted by the P-TEFb kinase complex. May be able to induce  chromatin unfolding. (from UniProt Q8WX92)
ZCCHC8 (ENST00000543897.5) at chr12:122471600-122500595 - Homo sapiens zinc finger CCHC-type containing 8 (ZCCHC8), transcript variant 5, mRNA. (from RefSeq NM_001350938)
RAD51 (ENST00000532743.6) at chr15:40695526-40731594 - Participates in a common DNA damage response pathway  associated with the activation of homologous recombination and  double-strand break repair. Binds to single and double stranded  DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex  DNA and forms helical nucleoprotein filaments. Plays a role in  regulating mitochondrial DNA copy number under conditions of  oxidative stress in the presence of RAD51C and XRCC3. (from UniProt Q06609)
RAD51 (ENST00000382643.7) at chr15:40695174-40731593 - Participates in a common DNA damage response pathway  associated with the activation of homologous recombination and  double-strand break repair. Binds to single and double stranded  DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex  DNA and forms helical nucleoprotein filaments. Plays a role in  regulating mitochondrial DNA copy number under conditions of  oxidative stress in the presence of RAD51C and XRCC3. (from UniProt Q06609)
UBE2T (ENST00000646651.1) at chr1:202331657-202341936 - Homo sapiens ubiquitin conjugating enzyme E2 T (UBE2T), transcript variant 1, mRNA. (from RefSeq NM_014176)
FANCD2 (ENST00000419585.5) at chr3:10026499-10101930 - Homo sapiens FA complementation group D2 (FANCD2), transcript variant 3, mRNA. (from RefSeq NM_001319984)
FANCD2 (ENST00000383807.5) at chr3:10026429-10101930 - Homo sapiens FA complementation group D2 (FANCD2), transcript variant 2, mRNA. (from RefSeq NM_001018115)
CHEK2 (ENST00000649563.1) at chr22:28687751-28741806 - Homo sapiens checkpoint kinase 2 (CHEK2), transcript variant 4, mRNA. (from RefSeq NM_001257387)
CHEK2 (ENST00000348295.7) at chr22:28687743-28741834 - Homo sapiens checkpoint kinase 2 (CHEK2), transcript variant 2, mRNA. (from RefSeq NM_145862)
ATR (ENST00000350721.9) at chr3:142449235-142578733 - Homo sapiens ATR serine/threonine kinase (ATR), transcript variant 1, mRNA. (from RefSeq NM_001184)
CHEK2 (ENST00000404276.6) at chr22:28687743-28741820 - Homo sapiens checkpoint kinase 2 (CHEK2), transcript variant 1, mRNA. (from RefSeq NM_007194)
CHEK2 (ENST00000382580.6) at chr22:28687763-28741838 - Homo sapiens checkpoint kinase 2 (CHEK2), transcript variant 3, mRNA. (from RefSeq NM_001005735)
FANCD2 (ENST00000287647.7) at chr3:10026414-10099660 - Homo sapiens FA complementation group D2 (FANCD2), transcript variant 1, mRNA. (from RefSeq NM_033084)
PALB2 (ENST00000261584.8) at chr16:23603170-23641310 - Homo sapiens partner and localizer of BRCA2 (PALB2), mRNA. (from RefSeq NM_024675)
UBE2K (ENST00000503368.5) at chr4:39698163-39778710 - Homo sapiens ubiquitin conjugating enzyme E2 K (UBE2K), transcript variant 6, mRNA. (from RefSeq NM_001312648)
UBE2K (ENST00000445950.2) at chr4:39698176-39779983 - Homo sapiens ubiquitin conjugating enzyme E2 K (UBE2K), transcript variant 2, mRNA. (from RefSeq NM_001111112)
UBE2K (ENST00000261427.10) at chr4:39698136-39782792 - Homo sapiens ubiquitin conjugating enzyme E2 K (UBE2K), transcript variant 1, mRNA. (from RefSeq NM_005339)
LMO4 (ENST00000370542.1) at chr1:87331668-87345408 - Homo sapiens LIM domain only 4 (LMO4), transcript variant 2, mRNA. (from RefSeq NM_001369491)
KDM5B (ENST00000367265.8) at chr1:202724495-202809470 - Homo sapiens lysine demethylase 5B (KDM5B), transcript variant 2, mRNA. (from RefSeq NM_006618)
KDM5B (ENST00000367264.7) at chr1:202727435-202808481 - Homo sapiens lysine demethylase 5B (KDM5B), transcript variant 1, mRNA. (from RefSeq NM_001314042)
BRD7 (ENST00000394688.7) at chr16:50315957-50368934 - Homo sapiens bromodomain containing 7 (BRD7), transcript variant 2, mRNA. (from RefSeq NM_013263)
DCLRE1A (ENST00000369305.1) at chr10:113834729-113854383 - Homo sapiens DNA cross-link repair 1A (DCLRE1A), transcript variant 1, mRNA. (from RefSeq NM_001271816)
BRD7 (ENST00000394689.2) at chr16:50319030-50368779 - Homo sapiens bromodomain containing 7 (BRD7), transcript variant 1, mRNA. (from RefSeq NM_001173984)
DCLRE1A (ENST00000361384.7) at chr10:113834725-113854082 - Homo sapiens DNA cross-link repair 1A (DCLRE1A), transcript variant 2, mRNA. (from RefSeq NM_014881)
HSPD1 (ENST00000345042.6) at chr2:197486586-197500274 - Homo sapiens heat shock protein family D (Hsp60) member 1 (HSPD1), transcript variant 2, mRNA. (from RefSeq NM_199440)
HSPD1 (ENST00000388968.8) at chr2:197486584-197499840 - Homo sapiens heat shock protein family D (Hsp60) member 1 (HSPD1), transcript variant 1, mRNA. (from RefSeq NM_002156)
LMO4 (ENST00000370544.10) at chr1:87328880-87348923 - Homo sapiens LIM domain only 4 (LMO4), transcript variant 1, mRNA. (from RefSeq NM_006769)
MORF4L1 (ENST00000558502.5) at chr15:78873030-78897077 - Homo sapiens mortality factor 4 like 1 (MORF4L1), transcript variant 3, mRNA. (from RefSeq NM_001265603)
MORF4L1 (ENST00000559345.5) at chr15:78873005-78897389 - Homo sapiens mortality factor 4 like 1 (MORF4L1), transcript variant 5, mRNA. (from RefSeq NM_001265605)
MORF4L1 (ENST00000331268.9) at chr15:78872814-78898133 - Homo sapiens mortality factor 4 like 1 (MORF4L1), transcript variant 2, mRNA. (from RefSeq NM_206839)
MORF4L1 (ENST00000426013.7) at chr15:78872890-78898139 - Homo sapiens mortality factor 4 like 1 (MORF4L1), transcript variant 1, mRNA. (from RefSeq NM_006791)
AURKA (ENST00000395914.5) at chr20:56369389-56392295 - Homo sapiens aurora kinase A (AURKA), transcript variant 3, mRNA. (from RefSeq NM_198434)
AURKA (ENST00000395911.5) at chr20:56369390-56392215 - Homo sapiens aurora kinase A (AURKA), transcript variant 1, mRNA. (from RefSeq NM_198433)
AURKA (ENST00000395913.7) at chr20:56369390-56392337 - Homo sapiens aurora kinase A (AURKA), transcript variant 4, mRNA. (from RefSeq NM_198435)
AURKA (ENST00000395915.7) at chr20:56369390-56392296 - Homo sapiens aurora kinase A (AURKA), transcript variant 6, mRNA. (from RefSeq NM_198437)
AURKA (ENST00000347343.6) at chr20:56369390-56392205 - Homo sapiens aurora kinase A (AURKA), transcript variant 2, mRNA. (from RefSeq NM_003600)
AURKA (ENST00000312783.10) at chr20:56369390-56392295 - Homo sapiens aurora kinase A (AURKA), transcript variant 5, mRNA. (from RefSeq NM_198436)
RNF8 (ENST00000469731.5) at chr6:37354091-37391231 - Homo sapiens ring finger protein 8 (RNF8), transcript variant 2, mRNA. (from RefSeq NM_183078)
RNF8 (ENST00000373479.9) at chr6:37353983-37394734 - Homo sapiens ring finger protein 8 (RNF8), transcript variant 3, non-coding RNA. (from RefSeq NR_046399)
CHEK2 (ENST00000650281.1) at chr22:28687766-28741806 - Serine/threonine-protein kinase which is required for  checkpoint-mediated cell cycle arrest, activation of DNA repair  and apoptosis in response to the presence of DNA double-strand  breaks. May also negatively regulate cell cycle progression during  unperturbed cell cycles. Following activation, phosphorylates  numerous effectors preferentially at the consensus sequence [L-X-  R-X-X-S/T]. Regulates cell cycle checkpoint arrest through  phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their  activity. Inhibition of CDC25 phosphatase activity leads to  increased inhibitory tyrosine phosphorylation of CDK-cyclin  complexes and blocks cell cycle progression. May also  phosphorylate NEK6 which is involved in G2/M cell cycle arrest.  Regulates DNA repair through phosphorylation of BRCA2, enhancing  the association of RAD51 with chromatin which promotes DNA repair  by homologous recombination. Also stimulates the transcription of  genes involved in DNA repair (including BRCA2) through the  phosphorylation and activation of the transcription factor FOXM1.  Regulates apoptosis through the phosphorylation of p53/TP53, MDM4  and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may  alleviate inhibition by MDM2, leading to accumulation of active  p53/TP53. Phosphorylation of MDM4 may also reduce degradation of  p53/TP53. Also controls the transcription of pro-apoptotic genes  through phosphorylation of the transcription factor E2F1. Tumor  suppressor, it may also have a DNA damage-independent function in  mitotic spindle assembly by phosphorylating BRCA1. Its absence may  be a cause of the chromosomal instability observed in some cancer  cells. (from UniProt O96017)
CHEK2 (ENST00000448511.5) at chr22:28687887-28734721 - Serine/threonine-protein kinase which is required for  checkpoint-mediated cell cycle arrest, activation of DNA repair  and apoptosis in response to the presence of DNA double-strand  breaks. May also negatively regulate cell cycle progression during  unperturbed cell cycles. Following activation, phosphorylates  numerous effectors preferentially at the consensus sequence [L-X-  R-X-X-S/T]. Regulates cell cycle checkpoint arrest through  phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their  activity. Inhibition of CDC25 phosphatase activity leads to  increased inhibitory tyrosine phosphorylation of CDK-cyclin  complexes and blocks cell cycle progression. May also  phosphorylate NEK6 which is involved in G2/M cell cycle arrest.  Regulates DNA repair through phosphorylation of BRCA2, enhancing  the association of RAD51 with chromatin which promotes DNA repair  by homologous recombination. Also stimulates the transcription of  genes involved in DNA repair (including BRCA2) through the  phosphorylation and activation of the transcription factor FOXM1.  Regulates apoptosis through the phosphorylation of p53/TP53, MDM4  and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may  alleviate inhibition by MDM2, leading to accumulation of active  p53/TP53. Phosphorylation of MDM4 may also reduce degradation of  p53/TP53. Also controls the transcription of pro-apoptotic genes  through phosphorylation of the transcription factor E2F1. Tumor  suppressor, it may also have a DNA damage-independent function in  mitotic spindle assembly by phosphorylating BRCA1. Its absence may  be a cause of the chromosomal instability observed in some cancer  cells. (from UniProt O96017)
CHEK2 (ENST00000433728.5) at chr22:28687887-28734721 - Serine/threonine-protein kinase which is required for  checkpoint-mediated cell cycle arrest, activation of DNA repair  and apoptosis in response to the presence of DNA double-strand  breaks. May also negatively regulate cell cycle progression during  unperturbed cell cycles. Following activation, phosphorylates  numerous effectors preferentially at the consensus sequence [L-X-  R-X-X-S/T]. Regulates cell cycle checkpoint arrest through  phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their  activity. Inhibition of CDC25 phosphatase activity leads to  increased inhibitory tyrosine phosphorylation of CDK-cyclin  complexes and blocks cell cycle progression. May also  phosphorylate NEK6 which is involved in G2/M cell cycle arrest.  Regulates DNA repair through phosphorylation of BRCA2, enhancing  the association of RAD51 with chromatin which promotes DNA repair  by homologous recombination. Also stimulates the transcription of  genes involved in DNA repair (including BRCA2) through the  phosphorylation and activation of the transcription factor FOXM1.  Regulates apoptosis through the phosphorylation of p53/TP53, MDM4  and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may  alleviate inhibition by MDM2, leading to accumulation of active  p53/TP53. Phosphorylation of MDM4 may also reduce degradation of  p53/TP53. Also controls the transcription of pro-apoptotic genes  through phosphorylation of the transcription factor E2F1. Tumor  suppressor, it may also have a DNA damage-independent function in  mitotic spindle assembly by phosphorylating BRCA1. Its absence may  be a cause of the chromosomal instability observed in some cancer  cells. (from UniProt O96017)
CHEK2 (ENST00000417588.5) at chr22:28687887-28734721 - Serine/threonine-protein kinase which is required for  checkpoint-mediated cell cycle arrest, activation of DNA repair  and apoptosis in response to the presence of DNA double-strand  breaks. May also negatively regulate cell cycle progression during  unperturbed cell cycles. Following activation, phosphorylates  numerous effectors preferentially at the consensus sequence [L-X-  R-X-X-S/T]. Regulates cell cycle checkpoint arrest through  phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their  activity. Inhibition of CDC25 phosphatase activity leads to  increased inhibitory tyrosine phosphorylation of CDK-cyclin  complexes and blocks cell cycle progression. May also  phosphorylate NEK6 which is involved in G2/M cell cycle arrest.  Regulates DNA repair through phosphorylation of BRCA2, enhancing  the association of RAD51 with chromatin which promotes DNA repair  by homologous recombination. Also stimulates the transcription of  genes involved in DNA repair (including BRCA2) through the  phosphorylation and activation of the transcription factor FOXM1.  Regulates apoptosis through the phosphorylation of p53/TP53, MDM4  and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may  alleviate inhibition by MDM2, leading to accumulation of active  p53/TP53. Phosphorylation of MDM4 may also reduce degradation of  p53/TP53. Also controls the transcription of pro-apoptotic genes  through phosphorylation of the transcription factor E2F1. Tumor  suppressor, it may also have a DNA damage-independent function in  mitotic spindle assembly by phosphorylating BRCA1. Its absence may  be a cause of the chromosomal instability observed in some cancer  cells. (from UniProt O96017)
CHEK2 (ENST00000405598.5) at chr22:28687762-28741800 - Serine/threonine-protein kinase which is required for  checkpoint-mediated cell cycle arrest, activation of DNA repair  and apoptosis in response to the presence of DNA double-strand  breaks. May also negatively regulate cell cycle progression during  unperturbed cell cycles. Following activation, phosphorylates  numerous effectors preferentially at the consensus sequence [L-X-  R-X-X-S/T]. Regulates cell cycle checkpoint arrest through  phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their  activity. Inhibition of CDC25 phosphatase activity leads to  increased inhibitory tyrosine phosphorylation of CDK-cyclin  complexes and blocks cell cycle progression. May also  phosphorylate NEK6 which is involved in G2/M cell cycle arrest.  Regulates DNA repair through phosphorylation of BRCA2, enhancing  the association of RAD51 with chromatin which promotes DNA repair  by homologous recombination. Also stimulates the transcription of  genes involved in DNA repair (including BRCA2) through the  phosphorylation and activation of the transcription factor FOXM1.  Regulates apoptosis through the phosphorylation of p53/TP53, MDM4  and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may  alleviate inhibition by MDM2, leading to accumulation of active  p53/TP53. Phosphorylation of MDM4 may also reduce degradation of  p53/TP53. Also controls the transcription of pro-apoptotic genes  through phosphorylation of the transcription factor E2F1. Tumor  suppressor, it may also have a DNA damage-independent function in  mitotic spindle assembly by phosphorylating BRCA1. Its absence may  be a cause of the chromosomal instability observed in some cancer  cells. (from UniProt O96017)
CHEK2 (ENST00000403642.5) at chr22:28687897-28734721 - Serine/threonine-protein kinase which is required for  checkpoint-mediated cell cycle arrest, activation of DNA repair  and apoptosis in response to the presence of DNA double-strand  breaks. May also negatively regulate cell cycle progression during  unperturbed cell cycles. Following activation, phosphorylates  numerous effectors preferentially at the consensus sequence [L-X-  R-X-X-S/T]. Regulates cell cycle checkpoint arrest through  phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their  activity. Inhibition of CDC25 phosphatase activity leads to  increased inhibitory tyrosine phosphorylation of CDK-cyclin  complexes and blocks cell cycle progression. May also  phosphorylate NEK6 which is involved in G2/M cell cycle arrest.  Regulates DNA repair through phosphorylation of BRCA2, enhancing  the association of RAD51 with chromatin which promotes DNA repair  by homologous recombination. Also stimulates the transcription of  genes involved in DNA repair (including BRCA2) through the  phosphorylation and activation of the transcription factor FOXM1.  Regulates apoptosis through the phosphorylation of p53/TP53, MDM4  and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may  alleviate inhibition by MDM2, leading to accumulation of active  p53/TP53. Phosphorylation of MDM4 may also reduce degradation of  p53/TP53. Also controls the transcription of pro-apoptotic genes  through phosphorylation of the transcription factor E2F1. Tumor  suppressor, it may also have a DNA damage-independent function in  mitotic spindle assembly by phosphorylating BRCA1. Its absence may  be a cause of the chromosomal instability observed in some cancer  cells. (from UniProt O96017)
CHEK2 (ENST00000402731.5) at chr22:28687897-28734721 - Serine/threonine-protein kinase which is required for  checkpoint-mediated cell cycle arrest, activation of DNA repair  and apoptosis in response to the presence of DNA double-strand  breaks. May also negatively regulate cell cycle progression during  unperturbed cell cycles. Following activation, phosphorylates  numerous effectors preferentially at the consensus sequence [L-X-  R-X-X-S/T]. Regulates cell cycle checkpoint arrest through  phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their  activity. Inhibition of CDC25 phosphatase activity leads to  increased inhibitory tyrosine phosphorylation of CDK-cyclin  complexes and blocks cell cycle progression. May also  phosphorylate NEK6 which is involved in G2/M cell cycle arrest.  Regulates DNA repair through phosphorylation of BRCA2, enhancing  the association of RAD51 with chromatin which promotes DNA repair  by homologous recombination. Also stimulates the transcription of  genes involved in DNA repair (including BRCA2) through the  phosphorylation and activation of the transcription factor FOXM1.  Regulates apoptosis through the phosphorylation of p53/TP53, MDM4  and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may  alleviate inhibition by MDM2, leading to accumulation of active  p53/TP53. Phosphorylation of MDM4 may also reduce degradation of  p53/TP53. Also controls the transcription of pro-apoptotic genes  through phosphorylation of the transcription factor E2F1. Tumor  suppressor, it may also have a DNA damage-independent function in  mitotic spindle assembly by phosphorylating BRCA1. Its absence may  be a cause of the chromosomal instability observed in some cancer  cells. (from UniProt O96017)
IFI16 (ENST00000368131.8) at chr1:159009892-159055155 - Homo sapiens interferon gamma inducible protein 16 (IFI16), transcript variant 2, mRNA. (from RefSeq NM_005531)
IFI16 (ENST00000295809.11) at chr1:159009927-159055155 - Homo sapiens interferon gamma inducible protein 16 (IFI16), transcript variant 3, mRNA. (from RefSeq NM_001364867)
IFI16 (ENST00000359709.7) at chr1:159010010-159055148 - Homo sapiens interferon gamma inducible protein 16 (IFI16), transcript variant 1, mRNA. (from RefSeq NM_001206567)
BRCA2 (ENST00000380152.7) at chr13:32315474-32400266 - Involved in double-strand break repair and/or homologous  recombination. Binds RAD51 and potentiates recombinational DNA  repair by promoting assembly of RAD51 onto single-stranded DNA  (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded  DNA, enabling RAD51 to displace replication protein-A (RPA) from  ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP  hydrolysis. May participate in S phase checkpoint activation.  Binds selectively to ssDNA, and to ssDNA in tailed duplexes and  replication fork structures. In concert with NPM1, regulates  centrosome duplication. (from UniProt P51587)
FANCD2 (ENST00000431693.1) at chr3:10028620-10041562 - Required for maintenance of chromosomal stability.  Promotes accurate and efficient pairing of homologs during  meiosis. Involved in the repair of DNA double-strand breaks, both  by homologous recombination and single-strand annealing. May  participate in S phase and G2 phase checkpoint activation upon DNA  damage. Plays a role in preventing breakage and loss of  missegregating chromatin at the end of cell division, particularly  after replication stress. Required for the targeting, or  stabilization, of BLM to non-centromeric abnormal structures  induced by replicative stress. Promotes BRCA2/FANCD1 loading onto  damaged chromatin. May also be involved in B-cell immunoglobulin  isotype switching. (from UniProt Q9BXW9)
ACACA (ENST00000614428.4) at chr17:37084994-37359116 - Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 2, mRNA. (from RefSeq NM_198839)
ACACA (ENST00000613687.4) at chr17_KI270857v1_alt:1320994-1595124 - Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 2, mRNA. (from RefSeq NM_198839)
ACACA (ENST00000616317.5) at chr17:37084992-37406836 - Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 1, mRNA. (from RefSeq NM_198834)
ACACA (ENST00000621312.4) at chr17_KI270857v1_alt:1322817-1535757 - Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 5, mRNA. (from RefSeq NM_198838)
ACACA (ENST00000619487.4) at chr17_KI270857v1_alt:1320988-1645936 - Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 1, mRNA. (from RefSeq NM_198834)
ACACA (ENST00000611803.2) at chr17_KI270857v1_alt:1320994-1535757 - Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 4, mRNA. (from RefSeq NM_198837)
ACACA (ENST00000617649.4) at chr17:37086817-37299767 - Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 5, mRNA. (from RefSeq NM_198838)
ACACA (ENST00000612895.4) at chr17:37084994-37299767 - Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 4, mRNA. (from RefSeq NM_198837)
UBE2D3 (ENST00000394804.6) at chr4:102794386-102827948 - Homo sapiens ubiquitin conjugating enzyme E2 D3 (UBE2D3), transcript variant 2, mRNA. (from RefSeq NM_181886)
UBE2D3 (ENST00000394801.8) at chr4:102795976-102827948 - Homo sapiens ubiquitin conjugating enzyme E2 D3 (UBE2D3), transcript variant 4, mRNA. (from RefSeq NM_181888)
UBE2D3 (ENST00000343106.9) at chr4:102796134-102827122 - Homo sapiens ubiquitin conjugating enzyme E2 D3 (UBE2D3), transcript variant 8, mRNA. (from RefSeq NM_181892)
UBE2D3 (ENST00000394803.9) at chr4:102795976-102828159 - Homo sapiens ubiquitin conjugating enzyme E2 D3 (UBE2D3), transcript variant 5, mRNA. (from RefSeq NM_181889)
UBE2D3 (ENST00000357194.10) at chr4:102797357-102868896 - Homo sapiens ubiquitin conjugating enzyme E2 D3 (UBE2D3), transcript variant 9, mRNA. (from RefSeq NM_181893)
UBE2D3 (ENST00000338145.7) at chr4:102797252-102868875 - Homo sapiens ubiquitin conjugating enzyme E2 D3 (UBE2D3), transcript variant 6, mRNA. (from RefSeq NM_181890)
CTCFL (ENST00000422869.6) at chr20:57506742-57525652 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 9, mRNA. (from RefSeq NM_001269047)
CTCFL (ENST00000609232.5) at chr20:57497164-57525652 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 2, mRNA. (from RefSeq NM_080618)
UBE2D3 (ENST00000453744.7) at chr4:102794383-102827551 - Homo sapiens ubiquitin conjugating enzyme E2 D3 (UBE2D3), transcript variant 7, mRNA. (from RefSeq NM_181891)
CTCFL (ENST00000608903.5) at chr20:57506742-57525107 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 16, mRNA. (from RefSeq NM_001269055)
CTCFL (ENST00000608263.5) at chr20:57497164-57524867 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 3, mRNA. (from RefSeq NM_001269041)
CTCFL (ENST00000432255.6) at chr20:57506742-57524867 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 10, mRNA. (from RefSeq NM_001269048)
CTCFL (ENST00000423479.7) at chr20:57495966-57525107 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 5, mRNA. (from RefSeq NM_001269043)
CTCFL (ENST00000371196.6) at chr20:57497168-57525579 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 4, mRNA. (from RefSeq NM_001269042)
CTCFL (ENST00000539382.5) at chr20:57506742-57525107 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 12, mRNA. (from RefSeq NM_001269050)
CTCFL (ENST00000429804.7) at chr20:57497164-57525652 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 8, mRNA. (from RefSeq NM_001269046)
CTCFL (ENST00000608440.5) at chr20:57499554-57524257 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 6, mRNA. (from RefSeq NM_001269044)
CTCFL (ENST00000433949.7) at chr20:57499554-57525107 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 11, mRNA. (from RefSeq NM_001269049)
CTCFL (ENST00000502686.6) at chr20:57499554-57525107 - Homo sapiens CCCTC-binding factor like (CTCFL), transcript variant 15, mRNA. (from RefSeq NM_001269054)
RNF168 (ENST00000318037.3) at chr3:196468783-196503768 - Homo sapiens ring finger protein 168 (RNF168), mRNA. (from RefSeq NM_152617)
H2AFX (ENST00000375167.1) at chr11:119093879-119095449 - Variant histone H2A which replaces conventional H2A in a  subset of nucleosomes. Nucleosomes wrap and compact DNA into  chromatin, limiting DNA accessibility to the cellular machineries  which require DNA as a template. Histones thereby play a central  role in transcription regulation, DNA repair, DNA replication and  chromosomal stability. DNA accessibility is regulated via a  complex set of post-translational modifications of histones, also  called histone code, and nucleosome remodeling. Required for  checkpoint-mediated arrest of cell cycle progression in response  to low doses of ionizing radiation and for efficient repair of DNA  double strand breaks (DSBs) specifically when modified by C-  terminal phosphorylation. (from UniProt P16104)
TOPBP1 (ENST00000260810.10) at chr3:133600238-133661941 - Homo sapiens DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant 1, mRNA. (from RefSeq NM_007027)
CCNE1 (ENST00000262643.8) at chr19:29811991-29824312 - Homo sapiens cyclin E1 (CCNE1), transcript variant 4, mRNA. (from RefSeq NM_001322261)
DHX9 (ENST00000367549.4) at chr1:182839347-182887982 - Homo sapiens DExH-box helicase 9 (DHX9), transcript variant 2, non-coding RNA. (from RefSeq NR_033302)
MRE11 (ENST00000407439.7) at chr11:94419866-94493843 - Component of the MRN complex, which plays a central role  in double-strand break (DSB) repair, DNA recombination,  maintenance of telomere integrity and meiosis. The complex  possesses single-strand endonuclease activity and double-strand-  specific 3'-5' exonuclease activity, which are provided by MRE11A.  RAD50 may be required to bind DNA ends and hold them in close  proximity. This could facilitate searches for short or long  regions of sequence homology in the recombining DNA templates, and  may also stimulate the activity of DNA ligases and/or restrict the  nuclease activity of MRE11A to prevent nucleolytic degradation  past a given point. The complex may also be required for DNA  damage signaling via activation of the ATM kinase. In telomeres  the MRN complex may modulate t-loop formation. (from UniProt P49959)
DCLRE1C (ENST00000378255.5) at chr10:14908171-14954048 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant h, mRNA. (from RefSeq NM_001289079)
DCLRE1C (ENST00000378254.5) at chr10:14908171-14954048 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant f, mRNA. (from RefSeq NM_001289077)
DCLRE1C (ENST00000378246.6) at chr10:14907879-14954095 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant b, mRNA. (from RefSeq NM_022487)
DCLRE1C (ENST00000357717.6) at chr10:14908166-14954058 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant e, mRNA. (from RefSeq NM_001289076)
DCLRE1C (ENST00000396817.6) at chr10:14908171-14954048 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant i, non-coding RNA. (from RefSeq NR_110297)
GTF2I (ENST00000443166.5) at chr7:74658031-74717066 - Homo sapiens general transcription factor IIi (GTF2I), transcript variant 6, mRNA. (from RefSeq NM_001280800)
MSH2 (ENST00000233146.6) at chr2:47402969-47483228 - Homo sapiens mutS homolog 2 (MSH2), transcript variant 1, mRNA. (from RefSeq NM_000251)
MSH2 (ENST00000543555.5) at chr2:47403067-47483227 - Homo sapiens mutS homolog 2 (MSH2), transcript variant 2, mRNA. (from RefSeq NM_001258281)
PTP4A2 (ENST00000602683.5) at chr1:31908658-31919109 - Homo sapiens protein tyrosine phosphatase 4A2 (PTP4A2), transcript variant 3, mRNA. (from RefSeq NM_001195100)
PTP4A2 (ENST00000647444.2) at chr1:31906421-31938368 - Homo sapiens protein tyrosine phosphatase 4A2 (PTP4A2), transcript variant 1, mRNA. (from RefSeq NM_080391)
MSH6 (ENST00000540021.5) at chr2:47783082-47806945 - Homo sapiens mutS homolog 6 (MSH6), transcript variant 2, mRNA. (from RefSeq NM_001281492)
MSH6 (ENST00000538136.1) at chr2:47783955-47806945 - Homo sapiens mutS homolog 6 (MSH6), transcript variant 4, mRNA. (from RefSeq NM_001281494)
MSH6 (ENST00000614496.4) at chr2:47783082-47806945 - Homo sapiens mutS homolog 6 (MSH6), transcript variant 3, mRNA. (from RefSeq NM_001281493)
MSH6 (ENST00000234420.9) at chr2:47783082-47810101 - Homo sapiens mutS homolog 6 (MSH6), transcript variant 1, mRNA. (from RefSeq NM_000179)
NBN (ENST00000265433.7) at chr8:89933336-89984716 - Homo sapiens nibrin (NBN), transcript variant 1, mRNA. (from RefSeq NM_002485)
H2AFX (ENST00000530167.1) at chr11:119093854-119095467 - Homo sapiens H2A histone family member X (H2AFX), mRNA. (from RefSeq NM_002105)
MLH1 (ENST00000536378.5) at chr3:36993350-37050842 - Homo sapiens mutL homolog 1 (MLH1), transcript variant 19, mRNA. (from RefSeq NM_001354626)
MLH1 (ENST00000455445.6) at chr3:36993798-37050706 - Homo sapiens mutL homolog 1 (MLH1), transcript variant 20, mRNA. (from RefSeq NM_001354627)
MLH1 (ENST00000435176.5) at chr3:36993804-37050844 - Homo sapiens mutL homolog 1 (MLH1), transcript variant 13, mRNA. (from RefSeq NM_001354620)
MLH1 (ENST00000539477.5) at chr3:36993777-37050842 - Homo sapiens mutL homolog 1 (MLH1), transcript variant 8, mRNA. (from RefSeq NM_001354615)
MRE11 (ENST00000323977.7) at chr11:94419876-94493874 - Homo sapiens MRE11 homolog, double strand break repair nuclease (MRE11), transcript variant 2, mRNA. (from RefSeq NM_005590)
MLH1 (ENST00000458205.6) at chr3:36993776-37050846 - Homo sapiens mutL homolog 1 (MLH1), transcript variant 7, mRNA. (from RefSeq NM_001258274)
MRE11 (ENST00000323929.7) at chr11:94415578-94493908 - Homo sapiens MRE11 homolog, double strand break repair nuclease (MRE11), transcript variant 1, mRNA. (from RefSeq NM_005591)
CCNE1 (ENST00000444983.6) at chr19:29812654-29824212 - Homo sapiens cyclin E1 (CCNE1), transcript variant 5, mRNA. (from RefSeq NM_001322262)
KPNA2 (ENST00000537025.6) at chr17:68035960-68046842 - Homo sapiens karyopherin subunit alpha 2 (KPNA2), transcript variant 1, mRNA. (from RefSeq NM_001320611)
KPNA2 (ENST00000330459.8) at chr17:68035735-68046854 - Homo sapiens karyopherin subunit alpha 2 (KPNA2), transcript variant 2, mRNA. (from RefSeq NM_002266)
PMS2 (ENST00000643595.1) at chr7:5973361-6009041 - Component of the post-replicative DNA mismatch repair  system (MMR). Heterodimerizes with MLH1 to form MutL alpha. DNA  repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-  MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to  the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary  complex in presence of RFC and PCNA is sufficient to activate  endonuclease activity of PMS2. It introduces single-strand breaks  near the mismatch and thus generates new entry points for the  exonuclease EXO1 to degrade the strand containing the mismatch.  DNA methylation would prevent cleavage and therefore assure that  only the newly mutated DNA strand is going to be corrected. MulL  alpha (MLH1-PMS2) interacts physically with the clamp loader  subunits of DNA polymerase III, suggesting that it may play a role  to recruit the DNA polymerase III to the site of the MMR. Also  implicated in DNA damage signaling, a process which induces cell  cycle arrest and can lead to apoptosis in case of major DNA  damages. (from UniProt P54278)
PMS2 (ENST00000382321.5) at chr7:5973399-6009019 - Component of the post-replicative DNA mismatch repair  system (MMR). Heterodimerizes with MLH1 to form MutL alpha. DNA  repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-  MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to  the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary  complex in presence of RFC and PCNA is sufficient to activate  endonuclease activity of PMS2. It introduces single-strand breaks  near the mismatch and thus generates new entry points for the  exonuclease EXO1 to degrade the strand containing the mismatch.  DNA methylation would prevent cleavage and therefore assure that  only the newly mutated DNA strand is going to be corrected. MulL  alpha (MLH1-PMS2) interacts physically with the clamp loader  subunits of DNA polymerase III, suggesting that it may play a role  to recruit the DNA polymerase III to the site of the MMR. Also  implicated in DNA damage signaling, a process which induces cell  cycle arrest and can lead to apoptosis in case of major DNA  damages. (from UniProt P54278)
DCLRE1C (ENST00000378289.8) at chr10:14897359-14954432 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant m, non-coding RNA. (from RefSeq NR_146960)
DCLRE1C (ENST00000378258.5) at chr10:14908171-14954072 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant n, non-coding RNA. (from RefSeq NR_146961)
DCLRE1C (ENST00000378249.5) at chr10:14908171-14954048 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant k, mRNA. (from RefSeq NM_001350966)
DCLRE1C (ENST00000378278.7) at chr10:14904613-14954096 - Homo sapiens DNA cross-link repair 1C (DCLRE1C), transcript variant o, non-coding RNA. (from RefSeq NR_146962)
RAD50 (ENST00000378823.8) at chr5:132556977-132646349 - Homo sapiens RAD50 double strand break repair protein (RAD50), mRNA. (from RefSeq NM_005732)
PTP4A2 (ENST00000649841.1) at chr1:31908263-31937775 - Homo sapiens protein tyrosine phosphatase 4A2 (PTP4A2), transcript variant 6, mRNA. (from RefSeq NM_001369859)
PTP4A2 (ENST00000602725.5) at chr1:31906421-31919483 - Homo sapiens protein tyrosine phosphatase 4A2 (PTP4A2), transcript variant 7, mRNA. (from RefSeq NM_001369860)
FOXA1 (ENST00000250448.3) at chr14:37589552-37595113 - Homo sapiens forkhead box A1 (FOXA1), mRNA. (from RefSeq NM_004496)
PTP4A2 (ENST00000457805.6) at chr1:31908534-31919368 - Homo sapiens protein tyrosine phosphatase 4A2 (PTP4A2), transcript variant 5, mRNA. (from RefSeq NM_001369858)
PMS2 (ENST00000265849.12) at chr7:5970925-6009049 - Homo sapiens PMS1 homolog 2, mismatch repair system component (PMS2), transcript variant 15, non-coding RNA. (from RefSeq NR_136154)
MLH1 (ENST00000231790.6) at chr3:36993332-37050918 - Homo sapiens mutL homolog 1 (MLH1), transcript variant 23, mRNA. (from RefSeq NM_001354630)
TRRAP (ENST00000355540.7) at chr7:98878490-99013243 - Homo sapiens transformation/transcription domain associated protein (TRRAP), transcript variant 2, mRNA. (from RefSeq NM_003496)
TRRAP (ENST00000359863.8) at chr7:98878490-99013243 - Homo sapiens transformation/transcription domain associated protein (TRRAP), transcript variant 1, mRNA. (from RefSeq NM_001244580)
RBBP4 (ENST00000373485.5) at chr1:32651234-32680657 - Core histone-binding subunit that may target chromatin  assembly factors, chromatin remodeling factors and histone  deacetylases to their histone substrates in a manner that is  regulated by nucleosomal DNA. Component of several complexes which  regulate chromatin metabolism. These include the chromatin  assembly factor 1 (CAF-1) complex, which is required for chromatin  assembly following DNA replication and DNA repair; the core  histone deacetylase (HDAC) complex, which promotes histone  deacetylation and consequent transcriptional repression; the  nucleosome remodeling and histone deacetylase complex (the NuRD  complex), which promotes transcriptional repression by histone  deacetylation and nucleosome remodeling; the PRC2/EED-EZH2  complex, which promotes repression of homeotic genes during  development; and the NURF (nucleosome remodeling factor) complex. (from UniProt Q09028)
PPP1CC (ENST00000340766.9) at chr12:110719908-110742939 - Homo sapiens protein phosphatase 1 catalytic subunit gamma (PPP1CC), transcript variant 2, mRNA. (from RefSeq NM_001244974)
PPP1CC (ENST00000335007.10) at chr12:110719680-110742891 - Homo sapiens protein phosphatase 1 catalytic subunit gamma (PPP1CC), transcript variant 1, mRNA. (from RefSeq NM_002710)
RBBP4 (ENST00000458695.6) at chr1:32651356-32680040 - Homo sapiens RB binding protein 4, chromatin remodeling factor (RBBP4), transcript variant 3, mRNA. (from RefSeq NM_001135256)
RBBP4 (ENST00000373493.10) at chr1:32651208-32686211 - Homo sapiens RB binding protein 4, chromatin remodeling factor (RBBP4), transcript variant 1, mRNA. (from RefSeq NM_005610)
RBBP4 (ENST00000414241.7) at chr1:32651142-32680053 - Homo sapiens RB binding protein 4, chromatin remodeling factor (RBBP4), transcript variant 2, mRNA. (from RefSeq NM_001135255)
CHEK1 (ENST00000428830.6) at chr11:125625974-125676255 - Homo sapiens checkpoint kinase 1 (CHEK1), transcript variant 2, mRNA. (from RefSeq NM_001114121)
CHEK1 (ENST00000534070.5) at chr11:125626341-125657147 - Homo sapiens checkpoint kinase 1 (CHEK1), transcript variant 3, mRNA. (from RefSeq NM_001274)
CHEK1 (ENST00000532449.6) at chr11:125626229-125656845 - Homo sapiens checkpoint kinase 1 (CHEK1), transcript variant 6, non-coding RNA. (from RefSeq NR_045205)
CHEK1 (ENST00000438015.6) at chr11:125625976-125657147 - Homo sapiens checkpoint kinase 1 (CHEK1), transcript variant 1, mRNA. (from RefSeq NM_001114122)
CHEK1 (ENST00000544373.5) at chr11:125625977-125655710 - Homo sapiens checkpoint kinase 1 (CHEK1), transcript variant 8, mRNA. (from RefSeq NM_001330428)
PPP1CA (ENST00000358239.8) at chr11:67398431-67401871 - Homo sapiens protein phosphatase 1 catalytic subunit alpha (PPP1CA), transcript variant 2, mRNA. (from RefSeq NM_206873)
PPP1CA (ENST00000312989.11) at chr11:67398183-67401793 - Homo sapiens protein phosphatase 1 catalytic subunit alpha (PPP1CA), transcript variant 3, mRNA. (from RefSeq NM_001008709)
PPP1CA (ENST00000376745.9) at chr11:67398183-67401858 - Homo sapiens protein phosphatase 1 catalytic subunit alpha (PPP1CA), transcript variant 1, mRNA. (from RefSeq NM_002708)
ESR1 (ENST00000440973.5) at chr6:151690496-152103274 - Homo sapiens estrogen receptor 1 (ESR1), transcript variant 4, mRNA. (from RefSeq NM_001122742)
ESR1 (ENST00000443427.5) at chr6:151807319-152103274 - Homo sapiens estrogen receptor 1 (ESR1), transcript variant 2, mRNA. (from RefSeq NM_001122740)
ESR1 (ENST00000206249.7) at chr6:151807551-152103274 - Homo sapiens estrogen receptor 1 (ESR1), transcript variant 6, mRNA. (from RefSeq NM_001291241)
CHEK1 (ENST00000524737.6) at chr11:125626558-125676041 - Serine/threonine-protein kinase which is required for  checkpoint-mediated cell cycle arrest and activation of DNA repair  in response to the presence of DNA damage or unreplicated DNA. May  also negatively regulate cell cycle progression during unperturbed  cell cycles. This regulation is achieved by a number of mechanisms  that together help to preserve the integrity of the genome.  Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to  and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of  CDC25A at 'Ser-178' and 'Thr-507' and phosphorylation of CDC25C at  'Ser-216' creates binding sites for 14-3-3 proteins which inhibit  CDC25A and CDC25C. Phosphorylation of CDC25A at 'Ser-76', 'Ser-  124', 'Ser-178', 'Ser-279' and 'Ser-293' promotes proteolysis of  CDC25A. Phosphorylation of CDC25A at 'Ser-76' primes the protein  for subsequent phosphorylation at 'Ser-79', 'Ser-82' and 'Ser-88'  by NEK11, which is required for polyubiquitination and degradation  of CDCD25A. Inhibition of CDC25 leads to increased inhibitory  tyrosine phosphorylation of CDK-cyclin complexes and blocks cell  cycle progression. Also phosphorylates NEK6. Binds to and  phosphorylates RAD51 at 'Thr-309', which promotes the release of  RAD51 from BRCA2 and enhances the association of RAD51 with  chromatin, thereby promoting DNA repair by homologous  recombination. Phosphorylates multiple sites within the C-terminus  of TP53, which promotes activation of TP53 by acetylation and  promotes cell cycle arrest and suppression of cellular  proliferation. Also promotes repair of DNA cross-links through  phosphorylation of FANCE. Binds to and phosphorylates TLK1 at  'Ser-743', which prevents the TLK1-dependent phosphorylation of  the chromatin assembly factor ASF1A. This may enhance chromatin  assembly both in the presence or absence of DNA damage. May also  play a role in replication fork maintenance through regulation of  PCNA. May regulate the transcription of genes that regulate cell-  cycle progression through the phosphorylation of histones.  Phosphorylates histone H3.1 (to form H3T11ph), which leads to  epigenetic inhibition of a subset of genes. May also phosphorylate  RB1 to promote its interaction with the E2F family of  transcription factors and subsequent cell cycle arrest. (from UniProt O14757)
ESR1 (ENST00000338799.9) at chr6:151804431-152099053 - Nuclear hormone receptor. The steroid hormones and their  receptors are involved in the regulation of eukaryotic gene  expression and affect cellular proliferation and differentiation  in target tissues. Ligand-dependent nuclear transactivation  involves either direct homodimer binding to a palindromic estrogen  response element (ERE) sequence or association with other DNA-  binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2,  Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding  induces a conformational change allowing subsequent or  combinatorial association with multiprotein coactivator complexes  through LXXLL motifs of their respective components. Mutual  transrepression occurs between the estrogen receptor (ER) and NF-  kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-  binding activity and inhibits NF-kappa-B-mediated transcription  from the IL6 promoter and displace RELA/p65 and associated  coregulators from the promoter. Recruited to the NF-kappa-B  response element of the CCL2 and IL8 promoters and can displace  CREBBP. Present with NF-kappa-B components RELA/p65 and NFKB1/p50  on ERE sequences. Can also act synergistically with NF-kappa-B to  activate transcription involving respective recruitment adjacent  response elements; the function involves CREBBP. Can activate the  transcriptional activity of TFF1. Also mediates membrane-initiated  estrogen signaling involving various kinase cascades. Isoform 3 is  involved in activation of NOS3 and endothelial nitric oxide  production. Isoforms lacking one or several functional domains are  thought to modulate transcriptional activity by competitive ligand  or DNA binding and/or heterodimerization with the full length  receptor. Isoform 3 can bind to ERE and inhibit isoform 1. (from UniProt P03372)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_007298.3 at chr17:43044295-43124115
NR_027676.1 at chr17:43044295-43125323
NM_007299.3 at chr17:43044295-43125451
NM_007297.3 at chr17:43044295-43125451
NM_007300.3 at chr17:43044295-43125483
NM_007294.3 at chr17:43044295-43125483

RefSeq Genes

BRCA1 at chr17:43044295-43125364 - (NM_007299) breast cancer type 1 susceptibility protein isoform 5
BRCA1 at chr17:43044295-43124115 - (NM_007298) breast cancer type 1 susceptibility protein isoform 4
BRCA1 at chr17:43044295-43125364 - (NM_007297) breast cancer type 1 susceptibility protein isoform 3
BRCA1 at chr17:43044295-43125364 - (NM_007294) breast cancer type 1 susceptibility protein isoform 1
BRCA1 at chr17:43044295-43125364 - (NM_007300) breast cancer type 1 susceptibility protein isoform 2
BRCA1 at chr17:43044295-43125364 - (NR_027676) 
NBR1 at chr17:43171214-43209862 - (NM_001291571) next to BRCA1 gene 1 protein isoform b
NBR1 at chr17:43171214-43211688 - (NM_001291572) next to BRCA1 gene 1 protein isoform c
NBR1 at chr17:43170409-43211688 - (NM_031862) next to BRCA1 gene 1 protein isoform a
NBR1 at chr17:43171214-43211688 - (NM_005899) next to BRCA1 gene 1 protein isoform a
BRAP at chr12:111642146-111685956 - (NM_006768) BRCA1-associated protein
BARD1 at chr2:214725646-214809683 - (NM_000465) BRCA1-associated RING domain protein 1 isoform 1
UIMC1 at chr5:176905006-177006779 - (NM_001199298) BRCA1-A complex subunit RAP80 isoform 1
BABAM1 at chr19:17267443-17279337 - (NM_014173) BRISC and BRCA1-A complex member 1 isoform 1
BARD1 at chr2:214725646-214809683 - (NM_001282543) BRCA1-associated RING domain protein 1 isoform 2
UIMC1 at chr5:176905005-177006794 - (NM_001317961) BRCA1-A complex subunit RAP80 isoform 2
UIMC1 at chr5:176905005-177006442 - (NM_016290) BRCA1-A complex subunit RAP80 isoform 1
BARD1 at chr2:214725646-214809683 - (NM_001282545) BRCA1-associated RING domain protein 1 isoform 3
BARD1 at chr2:214725646-214809683 - (NM_001282548) BRCA1-associated RING domain protein 1 isoform 4
BARD1 at chr2:214725646-214809683 - (NM_001282549) BRCA1-associated RING domain protein 1 isoform 5
UIMC1 at chr5:176905005-177006794 - (NM_001199297) BRCA1-A complex subunit RAP80 isoform 1
BABAM1 at chr19:17267376-17279353 - (NM_001288756) BRISC and BRCA1-A complex member 1 isoform 1
BABAM1 at chr19:17267376-17279353 - (NM_001033549) BRISC and BRCA1-A complex member 1 isoform 1
BRAT1 at chr7:2537810-2555524 - (NM_152743) BRCA1-associated ATM activator 1 isoform 2
ABRAXAS1 at chr4:83459517-83485100 - (NM_139076) BRCA1-A complex subunit Abraxas 1 isoform 1
BABAM2 at chr2:27890615-28338900 - (NM_001329113) BRISC and BRCA1-A complex member 2 isoform 1
BABAM2 at chr2:27890615-28338900 - (NM_001329115) BRISC and BRCA1-A complex member 2 isoform 6
BABAM2 at chr2:27890615-28338900 - (NM_001329114) BRISC and BRCA1-A complex member 2 isoform 5
BABAM2 at chr2:27888709-28338900 - (NM_001329112) BRISC and BRCA1-A complex member 2 isoform 2
BABAM2 at chr2:27890615-28338900 - (NM_004899) BRISC and BRCA1-A complex member 2 isoform 1
BABAM2 at chr2:27890615-28338900 - (NM_199194) BRISC and BRCA1-A complex member 2 isoform 2
BABAM2 at chr2:27890615-28338900 - (NM_199192) BRISC and BRCA1-A complex member 2 isoform 3
BABAM2 at chr2:27890729-28338900 - (NM_001261840) BRISC and BRCA1-A complex member 2 isoform 4
BABAM2 at chr2:27890615-28338900 - (NM_199191) BRISC and BRCA1-A complex member 2 isoform 2
BABAM2 at chr2:27890615-28338900 - (NM_199193) BRISC and BRCA1-A complex member 2 isoform 3
BRAT1 at chr7:2537810-2555524 - (NM_001350626) BRCA1-associated ATM activator 1 isoform 1
BRAT1 at chr7:2537810-2555524 - (NM_001350627) BRCA1-associated ATM activator 1 isoform 3
ABRAXAS1 at chr4:83459517-83485100 - (NM_001345962) BRCA1-A complex subunit Abraxas 1 isoform 2
BABAM1 at chr19:17267376-17279353 - (NM_001288757) BRISC and BRCA1-A complex member 1 isoform 2

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

neighbor of BRCA1 gene 2 (non-protein coding), transcript variant 2 at chr17:43125557-43153671 - (NR_138145.1)
BRISC and BRCA1 A complex member 2, transcript variant 13 at chr2:27890615-28338901 - (NR_137439.1)
BRISC and BRCA1 A complex member 2, transcript variant 11 at chr2:27890615-28338901 - (NR_137437.1)
BRCA1 associated RING domain 1, transcript variant 7 at chr2:214725646-214809711 - (NR_104215.1)
BRCA1, DNA repair associated, transcript variant 6 at chr17:43044295-43125323 - (NR_027676.1)
BRISC and BRCA1 A complex member 2, transcript variant 2 at chr2:27890615-28338901 - (NM_199194.2)
BRISC and BRCA1 A complex member 2, transcript variant 5 at chr2:27890615-28338901 - (NM_199192.2)
BRCA1 associated ATM activator 1, transcript variant 2 at chr7:2537810-2555758 - (NM_152743.3)
BRCA1 interacting protein C-terminal helicase 1 at chr17:61679186-61863559 - (NM_032043.2)
BRISC and BRCA1 A complex member 1, transcript variant 2 at chr19:17267376-17279353 - (NM_014173.3)
BRCA1, DNA repair associated, transcript variant 5 at chr17:43044295-43125451 - (NM_007299.3)
BRCA1, DNA repair associated, transcript variant 3 at chr17:43044295-43125451 - (NM_007297.3)
BRCA1 associated protein at chr12:111642146-111685996 - (NM_006768.4)
BRCA1 associated protein 1 at chr3:52401004-52410105 - (NM_004656.3)
BRCA1 associated ATM activator 1, transcript variant 1 at chr7:2537810-2555758 - (NM_001350626.1)
BRISC and BRCA1 A complex member 2, transcript variant 10 at chr2:27890615-28338901 - (NM_001329115.1)
BRISC and BRCA1 A complex member 2, transcript variant 8 at chr2:27890615-28338901 - (NM_001329113.1)
BRISC and BRCA1 A complex member 1, transcript variant 4 at chr19:17267376-17279353 - (NM_001288757.1)
BRCA1 associated RING domain 1, transcript variant 5 at chr2:214725646-214809711 - (NM_001282549.1)
BRCA1 associated RING domain 1, transcript variant 3 at chr2:214725646-214809711 - (NM_001282545.1)
BRISC and BRCA1 A complex member 2, transcript variant 6 at chr2:27890615-28338901 - (NM_001261840.1)
BRISC and BRCA1 A complex member 1, transcript variant 1 at chr19:17267376-17279353 - (NM_001033549.2)
BRCA1 associated RING domain 1, transcript variant 1 at chr2:214725646-214809711 - (NM_000465.3)
BRCA1/BRCA2-containing complex subunit 3, transcript variant 2 at chrX:155071420-155123074 - (NM_001018055.2)
BRCA1/BRCA2-containing complex subunit 3, transcript variant 3 at chrX:155071420-155123074 - (NM_001242640.1)
BRCA1 associated RING domain 1, transcript variant 2 at chr2:214725646-214809711 - (NM_001282543.1)
BRCA1 associated RING domain 1, transcript variant 4 at chr2:214725646-214809711 - (NM_001282548.1)
BRISC and BRCA1 A complex member 1, transcript variant 3 at chr19:17267376-17279353 - (NM_001288756.1)
BRISC and BRCA1 A complex member 2, transcript variant 7 at chr2:27888709-28338901 - (NM_001329112.1)
BRISC and BRCA1 A complex member 2, transcript variant 9 at chr2:27890615-28338901 - (NM_001329114.1)
abraxas 1, BRCA1 A complex subunit, transcript variant 2 at chr4:83460939-83485178 - (NM_001345962.1)
BRCA1 associated ATM activator 1, transcript variant 3 at chr7:2537810-2555758 - (NM_001350627.1)
BRISC and BRCA1 A complex member 2, transcript variant 1 at chr2:27890615-28338901 - (NM_004899.4)
BRCA1, DNA repair associated, transcript variant 1 at chr17:43044295-43125483 - (NM_007294.3)
BRCA1, DNA repair associated, transcript variant 4 at chr17:43044295-43124115 - (NM_007298.3)
BRCA1, DNA repair associated, transcript variant 2 at chr17:43044295-43125483 - (NM_007300.3)
BRCA1/BRCA2-containing complex subunit 3, transcript variant 1 at chrX:155071420-155123074 - (NM_024332.3)
abraxas 1, BRCA1 A complex subunit, transcript variant 1 at chr4:83460939-83485137 - (NM_139076.2)
BRISC and BRCA1 A complex member 2, transcript variant 3 at chr2:27890615-28338901 - (NM_199191.2)
BRISC and BRCA1 A complex member 2, transcript variant 4 at chr2:27890615-28338901 - (NM_199193.2)
neighbor of BRCA1 gene 2 (non-protein coding), transcript variant 1 at chr17:43125557-43145228 - (NR_003108.2)
BRCA1 associated RING domain 1, transcript variant 6 at chr2:214725646-214809711 - (NR_104212.1)
BRCA1 associated RING domain 1, transcript variant 8 at chr2:214725646-214809711 - (NR_104216.1)
BRISC and BRCA1 A complex member 2, transcript variant 12 at chr2:27890615-28338901 - (NR_137438.1)
BRISC and BRCA1 A complex member 2, transcript variant 14 at chr2:27890615-28338901 - (NR_137440.1)
BRCA1 associated ATM activator 1, transcript variant 4 at chr7:2537810-2555758 - (NR_146879.1)

NCBI RefSeq genes, predicted subset (XM_* or XR_*)

abraxas 1, BRCA1 A complex subunit, transcript variant X2 at chr4:83463547-83485137 - (XR_001741334.2)
BRCA1/BRCA2-containing complex subunit 3, transcript variant X1 at chrX:155071403-155120169 - (XM_017029838.1)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X13 at chr17:61681266-61779349 - (XM_017025202.1)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X8 at chr17:61681266-61857178 - (XM_017025200.1)
BRCA1 associated protein, transcript variant X4 at chr12:111642146-111686023 - (XM_017019994.1)
BRCA1 associated protein, transcript variant X2 at chr12:111642311-111685966 - (XM_017019992.1)
BRCA1 associated ATM activator 1, transcript variant X6 at chr7:2537851-2555715 - (XM_017011834.1)
BRCA1 associated protein 1, transcript variant X5 at chr3:52401004-52410030 - (XM_017007303.2)
BRCA1 associated RING domain 1, transcript variant X1 at chr2:214725645-214809660 - (XM_017004613.1)
BRCA1 associated protein 1, transcript variant X4 at chr3:52401004-52410030 - (XM_011534152.2)
BRCA1 associated protein 1, transcript variant X2 at chr3:52401004-52410030 - (XM_011534150.3)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X12 at chr17:61778679-61863990 - (XM_011525341.3)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X10 at chr17:61715992-61864120 - (XM_011525339.3)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X6 at chr17:61681266-61863988 - (XM_011525337.2)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X4 at chr17:61681266-61863991 - (XM_011525335.3)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X2 at chr17:61681266-61863992 - (XM_011525333.3)
BRCA1 associated ATM activator 1, transcript variant X10 at chr7:2537851-2555717 - (XM_011515186.2)
BRCA1 associated ATM activator 1, transcript variant X9 at chr7:2537851-2555753 - (XM_011515183.1)
BRCA1 associated ATM activator 1, transcript variant X5 at chr7:2537851-2555716 - (XM_011515181.2)
BRCA1 associated ATM activator 1, transcript variant X1 at chr7:2537851-2555490 - (XM_011515178.1)
BRCA1/BRCA2-containing complex subunit 3, transcript variant X2 at chrX:155071410-155126766 - (XM_005274751.4)
BRCA1 associated protein, transcript variant X1 at chr12:111642146-111685973 - (XM_005253944.4)
abraxas 1, BRCA1 A complex subunit, transcript variant X1 at chr4:83460939-83485095 - (XM_005263280.5)
BRCA1 associated ATM activator 1, transcript variant X7 at chr7:2537851-2555725 - (XM_011515177.2)
BRCA1 associated ATM activator 1, transcript variant X3 at chr7:2537851-2555719 - (XM_011515179.2)
BRCA1 associated ATM activator 1, transcript variant X2 at chr7:2537851-2555506 - (XM_011515182.2)
BRCA1 associated ATM activator 1, transcript variant X8 at chr7:2537851-2554402 - (XM_011515184.3)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X1 at chr17:61681266-61863991 - (XM_011525332.3)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X3 at chr17:61681266-61863273 - (XM_011525334.2)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X5 at chr17:61681266-61863988 - (XM_011525336.2)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X7 at chr17:61681266-61857178 - (XM_011525338.2)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X11 at chr17:61686060-61864116 - (XM_011525340.3)
BRCA1 associated protein 1, transcript variant X1 at chr3:52401004-52410030 - (XM_011534149.3)
BRCA1 associated protein 1, transcript variant X3 at chr3:52401004-52410030 - (XM_011534151.3)
BRCA1 associated protein, transcript variant X6 at chr12:111642146-111685935 - (XM_011538789.3)
BRCA1 associated RING domain 1, transcript variant X3 at chr2:214739081-214809660 - (XM_017004614.1)
BRCA1 associated ATM activator 1, transcript variant X4 at chr7:2537851-2555519 - (XM_017011833.1)
BRCA1 associated ATM activator 1, transcript variant X11 at chr7:2537851-2555715 - (XM_017011836.2)
BRCA1 associated protein, transcript variant X3 at chr12:111642311-111685986 - (XM_017019993.1)
BRCA1 associated protein, transcript variant X5 at chr12:111642311-111680462 - (XM_017019995.1)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X9 at chr17:61681266-61817977 - (XM_017025201.1)
BRCA1 interacting protein C-terminal helicase 1, transcript variant X14 at chr17:61681266-61780343 - (XM_017025203.1)
BRCA1 associated ATM activator 1, transcript variant X12 at chr7:2537851-2540883 - (XM_024446682.1)
BRCA1 associated RING domain 1, transcript variant X2 at chr2:214728538-214809660 - (XR_002959322.1)

Non-Human RefSeq Genes

BRCA1 at chr17:43045678-43124096 - (NM_001045493) breast cancer type 1 susceptibility protein homolog
BRCA1 at chr17:43045692-43124096 - (NM_001013416) breast cancer type 1 susceptibility protein homolog
BRCA1 at chr17:43045702-43124096 - (NM_178573) breast cancer type 1 susceptibility protein homolog
Brca1 at chr17:43045686-43168272 - (NM_012514) breast cancer type 1 susceptibility protein homolog
Brca1 at chr17:43044303-43124119 - (NM_009764) breast cancer type 1 susceptibility protein homolog
BRCA1 at chr17:43045678-43124096 - (NM_001301366) breast cancer type 1 susceptibility protein
BRCA1 at chr17:43045678-43124096 - (NM_001302103) breast cancer type 1 susceptibility protein
BRCA1 at chr17:43045678-43124096 - (NM_001114949) breast cancer type 1 susceptibility protein homolog
BRCA1 at chr17:43045678-43124096 - (NM_001308668) breast cancer type 1 susceptibility protein
BRCA1 at chr17:43045678-43124096 - (NM_001301758) breast cancer type 1 susceptibility protein
NBR1 at chr17:43171249-43211471 - (NM_001133837) next to BRCA1 gene 1 protein
NBR1 at chr17:43171222-43210130 - (NM_001100367) next to BRCA1 gene 1 protein
UIMC1 at chr5:176905045-176982625 - (NM_001038061) BRCA1-A complex subunit RAP80 isoform 1
FAM175A at chr4:83462826-83485079 - (NM_001031144) BRCA1-A complex subunit Abraxas
BRAT1 at chr7:2537939-2555648 - (NM_001206455) BRCA1-associated ATM activator 1
Brap at chr12:111642507-111685990 - (NM_028227) BRCA1-associated protein isoform 1
Abraxas1 at chr4:83462604-83485081 - (NM_172405) BRCA1-A complex subunit Abraxas 1
Babam1 at chr19:17267447-17279051 - (NM_026636) BRISC and BRCA1-A complex member 1
BRE at chr2:27894557-28338519 - (NM_001008458) BRISC and BRCA1-A complex member 2
Babam2 at chr2:27890792-28338637 - (NM_199270) BRISC and BRCA1-A complex member 2
Bard1 at chr2:214728607-214809543 - (NM_022622) BRCA1-associated RING domain protein 1
babam1 at chr19:17268876-17279018 - (NM_001003752) BRISC and BRCA1-A complex member 1
brap at chr12:111644199-111685792 - (NM_001002466) BRCA1-associated protein
babam2 at chr2:27894560-28338513 - (NM_001017777) BRISC and BRCA1-A complex member 2
BABAM2 at chr2:27890796-28338637 - (NM_001102274) BRISC and BRCA1-A complex member 2
Uimc1 at chr5:176905039-176982621 - (NM_001013884) BRCA1-A complex subunit RAP80
Babam2 at chr2:27894527-28338570 - (NM_144541) BRISC and BRCA1-A complex member 2 isoform V
Bard1 at chr2:214728249-214809543 - (NM_007525) BRCA1-associated RING domain protein 1
Brap at chr12:111642507-111683308 - (NM_001289544) BRCA1-associated protein isoform 3
Brap at chr12:111642507-111685990 - (NM_001289543) BRCA1-associated protein isoform 2
ABRAXAS1 at chr8:18088210-18089884 - (NM_001015516) BRCA1-A complex subunit Abraxas 1
ABRAXAS1 at chr4:83462462-83485072 - (NM_001015516) BRCA1-A complex subunit Abraxas 1
Babam1 at chr19:17267461-17279048 - (NM_001006964) BRISC and BRCA1-A complex member 1
Uimc1 at chr5:176904842-176982621 - (NM_001359758) BRCA1-A complex subunit RAP80 isoform 3
Uimc1 at chr5:176904842-176982621 - (NM_011307) BRCA1-A complex subunit RAP80 isoform 1
Uimc1 at chr5:176904842-176982621 - (NM_001359757) BRCA1-A complex subunit RAP80 isoform 1
UIMC1 at chr5:176905061-176982621 - (NM_001097447) BRCA1-A complex subunit RAP80
Uimc1 at chr5:176904842-176982621 - (NM_001293660) BRCA1-A complex subunit RAP80 isoform 2
Brat1 at chr7:2538064-2554437 - (NM_001276287) BRCA1-associated ATM activator 1 isoform 3
Brat1 at chr7:2538064-2554437 - (NM_181066) BRCA1-associated ATM activator 1 isoform 2
Babam2 at chr2:27929336-28338570 - (NM_181280) BRISC and BRCA1-A complex member 2 isoform IV
Babam2 at chr2:27894527-28338570 - (NM_181279) BRISC and BRCA1-A complex member 2 isoform I
Babam2 at chr2:27987995-28338570 - (NM_181281) BRISC and BRCA1-A complex member 2 isoform III
Babam2 at chr2:27929833-28338570 - (NM_181282) BRISC and BRCA1-A complex member 2 isoform II
BABAM1 at chr19:17268759-17279332 - (NM_001076801) BRISC and BRCA1-A complex member 1
Nbr1 at chr17:43171097-43211476 - (NM_001252223) next to BRCA1 gene 1 protein isoform 3
Nbr1 at chr17:43171097-43211476 - (NM_008676) next to BRCA1 gene 1 protein isoform 1
Nbr1 at chr17:43171097-43211476 - (NM_001252222) next to BRCA1 gene 1 protein isoform 2
Nbr1 at chr17:43170467-43211476 - (NM_001252220) next to BRCA1 gene 1 protein isoform 1
Nbr1 at chr17:43171211-43211401 - (NM_001024765) next to BRCA1 gene 1 protein
BARD1 at chr2:214728568-214809550 - (NM_001192701) BRCA1-associated RING domain protein 1
BARD1 at chr2:214728688-214781459 - (NM_001031246) BRCA1-associated RING domain protein 1
BRAP at chr12:111643936-111683254 - (NM_001079761) BRCA1-associated protein
BRAP at chr12:111643129-111685926 - (NM_001099008) BRCA1-associated protein
UIMC1 at chr5:176905045-176982625 - (NM_001113222) BRCA1-A complex subunit RAP80 isoform 2
Babam2 at chr2:27894527-28338569 - (NM_001281577) BRISC and BRCA1-A complex member 2
babam2 at chr2:27894557-28338513 - (NM_001005716) BRISC and BRCA1-A complex member 2
babam1.L at chr19:17268870-17279048 - (NM_001092916) BRISC and BRCA1-A complex member 1
babam2.L at chr2:27894557-28338513 - (NM_001092182) BRISC and BRCA1-A complex member 2
BABAM1 at chr19:17267454-17279337 - (NM_001132843) BRISC and BRCA1-A complex member 1
BABAM2 at chr2:27890771-28338900 - (NM_001131287) BRISC and BRCA1-A complex member 2
Abraxas1 at chr4:83462610-83485081 - (NM_001009633) BRCA1-A complex subunit Abraxas 1
babam1 at chr19:17268870-17279048 - (NM_001011287) BRISC and BRCA1-A complex member 1
Brap at chr12:111643249-111685899 - (NM_001271194) BRCA1-associated protein
brip1.L at chr17:61776398-61861551 - (NM_001089803) BRCA1 interacting protein C-terminal helicase 1 L homeolog
BRAP at chr12:111642348-111685813 - (NM_001265936) BRCA1-associated protein
BRAP at chr12:111644088-111685971 - (NM_001246552) BRCA1-associated protein
brap.S at chr12:111644283-111685792 - (NM_001089891) BRCA1 associated protein S homeolog
brap.L at chr12:111644283-111685792 - (NM_001090983) BRCA1 associated protein L homeolog
bard1.L at chr2:214728688-214797110 - (NM_001088662) BRCA1 associated RING domain 1 L homeolog
nbr1.L at chr17:43175797-43210074 - (NM_001086498) neighbor of BRCA1 gene 1 L homeolog
UIMC1 at chr5:176905006-177006756 - (NM_001280463) BRCA1-A complex subunit RAP80
BABAM1 at chr19:17267460-17279337 - (NM_001287628) BRISC and BRCA1-A complex member 1
BABAM1 at chr19:17267417-17279353 - (NM_001194597) BRISC and BRCA1-A complex member 1

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045086-43091851
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093013-43170245
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093585-43125483
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43094482-43125343
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43104225-43125326
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045086-43091851
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093013-43170245
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43094482-43125343
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43104225-43125326
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044295-43125483
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045086-43091851
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093013-43170245
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43094482-43125343
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43104225-43125326
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093013-43170245
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093013-43170245
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093013-43170245
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093013-43170245
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43124026-43125364

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43091098-43125315

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044295-43125370
BRCA1 at chr17:43044805-43125451
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045563-43125329
BRCA1 at chr17:43045629-43125402
BRCA1 at chr17:43045629-43125483
BRCA1 at chr17:43045678-43125288
BRCA1 at chr17:43045678-43125356
BRCA1 at chr17:43063344-43104916
BRCA1 at chr17:43063344-43125359
BRCA1 at chr17:43063360-43125402
BRCA1 at chr17:43067274-43071066
BRCA1 at chr17:43076488-43082760
BRCA1 at chr17:43076488-43104916
BRCA1 at chr17:43076537-43091824
BRCA1 at chr17:43091098-43125315
BRCA1 at chr17:43093570-43095866
BRCA1 at chr17:43093584-43125323
BRCA1 at chr17:43093586-43125364
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125300
BRCA1 at chr17:43094112-43125450
BRCA1 at chr17:43094170-43104891
BRCA1 at chr17:43095846-43125353
BRCA1 at chr17:43099831-43125370
BRCA1 at chr17:43104189-43125321
BRCA1 at chr17:43124026-43125364

International Knockout Mouse Consortium Genes Mapped to Human Genome

Brca1_44161 at chr17:43044295-43125483
Brca1_VG15642 at chr17:43044295-43125483

Alias of STS Marker

BRCA1 at chr17:42991679-43191967 - (BRCA1)

Human Aligned mRNA Search Results

U76638 - Human BRCA1-associated RING domain protein (BARD1) mRNA, complete cds.
U64805 - Homo sapiens Brca1-delta11b (Brca1) mRNA, complete cds.
JF790287 - Homo sapiens BRCA1 associated RING domain 1 isoform pi (BARD1) mRNA, partial cds.
JF790286 - Homo sapiens BRCA1 associated RING domain 1 isoform eta (BARD1) mRNA, complete cds.
JF790285 - Homo sapiens BRCA1 associated RING domain 1 isoform epsilon (BARD1) mRNA, partial cds.
JF790284 - Homo sapiens BRCA1 associated RING domain 1 isoform delta (BARD1) mRNA, complete cds.
JF790283 - Homo sapiens BRCA1 associated RING domain 1 isoform phi (BARD1) mRNA, complete cds.
JF790282 - Homo sapiens BRCA1 associated RING domain 1 isoform gamma (BARD1) mRNA, complete cds.
JF790281 - Homo sapiens BRCA1 associated RING domain 1 isoform beta (BARD1) mRNA, complete cds.
JF790280 - Homo sapiens BRCA1 associated RING domain 1 isoform alfa (BARD1) mRNA, complete cds.
DQ333387 - Homo sapiens BRCA1 isoform PI21-delta2-21 mRNA, complete cds, alternatively spliced.
DQ333386 - Homo sapiens BRCA1 isoform E1aA-delta2-17 mRNA, complete cds, alternatively spliced.
BC136698 - Homo sapiens BRCA1 associated protein, mRNA (cDNA clone MGC:168311 IMAGE:9020688), complete cds.
BC136699 - Homo sapiens BRCA1 associated protein, mRNA (cDNA clone MGC:168312 IMAGE:9020689), complete cds.
BC126426 - Homo sapiens BRCA1 associated RING domain 1, mRNA (cDNA clone MGC:161704 IMAGE:8992142), complete cds.
BC126428 - Homo sapiens BRCA1 associated RING domain 1, mRNA (cDNA clone MGC:161706 IMAGE:8992144), complete cds.
BC101472 - Homo sapiens BRCA1 interacting protein C-terminal helicase 1, mRNA (cDNA clone MGC:126521 IMAGE:8068978), complete cds.
BC101474 - Homo sapiens BRCA1 interacting protein C-terminal helicase 1, mRNA (cDNA clone MGC:126523 IMAGE:8068980), complete cds.
BC002999 - Homo sapiens BRCA1/BRCA2-containing complex, subunit 3, mRNA (cDNA clone MGC:3961 IMAGE:2821917), complete cds.
BC006540 - Homo sapiens BRCA1/BRCA2-containing complex, subunit 3, mRNA (cDNA clone MGC:2329 IMAGE:2821917), complete cds.
BC001596 - Homo sapiens BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase), mRNA (cDNA clone MGC:1530 IMAGE:3543914), complete cds.
AB208878 - Homo sapiens mRNA for BRCA1 associated protein variant protein.
AY597810 - Homo sapiens chromosome 17 neighbor of BRCA1 gene 2 (NBR2) mRNA, complete cds, alternatively spliced.
AY438031 - Homo sapiens BRCA1/BRCA2-containing complex subunit 45 (BRE) mRNA, complete cds.
AY438030 - Homo sapiens BRCA1/BRCA2-containing complex subunit 36 (BRCC36) mRNA, complete cds.
AK223409 - Homo sapiens mRNA for BRCA1 associated RING domain 1 variant, clone: FCC109A11.
AF464935 - Homo sapiens cofactor of BRCA1 (COBRA1) mRNA, complete cds.
AF360549 - Homo sapiens BRCA1-binding helicase-like protein BACH1 mRNA, complete cds.
AF151109 - Homo sapiens putative BRCA1-interacting protein (BRIP1) mRNA, partial cds.
AF035620 - Homo sapiens BRCA1-associated protein 2 (BRAP2) mRNA, complete cds.
BC030969 - Homo sapiens breast cancer 1, early onset, mRNA (cDNA clone IMAGE:4804551), partial cds.
BC062429 - Homo sapiens breast cancer 1, early onset, mRNA (cDNA clone IMAGE:3686198), partial cds.
BC072418 - Homo sapiens breast cancer 1, early onset, mRNA (cDNA clone IMAGE:6181860), complete cds.
BC085615 - Homo sapiens breast cancer 1, early onset, mRNA (cDNA clone IMAGE:6042052), partial cds.
BC106745 - Homo sapiens breast cancer 1, early onset, mRNA (cDNA clone IMAGE:40017569), partial cds.
BC106746 - Homo sapiens breast cancer 1, early onset, mRNA (cDNA clone IMAGE:40017570), partial cds.
BC115037 - Homo sapiens breast cancer 1, early onset, mRNA (cDNA clone MGC:131629 IMAGE:7961446), complete cds.
MG566100 - Homo sapiens isolate B5 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566101 - Homo sapiens isolate B6 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566102 - Homo sapiens isolate B7 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566103 - Homo sapiens isolate B10 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566104 - Homo sapiens isolate B11 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566105 - Homo sapiens isolate B12 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566106 - Homo sapiens isolate B15 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566107 - Homo sapiens isolate B25 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566108 - Homo sapiens isolate B36 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566109 - Homo sapiens isolate B38 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566110 - Homo sapiens isolate B39 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566111 - Homo sapiens isolate B40 BRCA1 protein (BRCA1) mRNA, partial cds.
MG566112 - Homo sapiens isolate CONTROL1B BRCA1 protein (BRCA1) mRNA, partial cds.
MG566113 - Homo sapiens isolate CONTROL2B BRCA1 protein (BRCA1) mRNA, partial cds.
MG566114 - Homo sapiens isolate CONTROL3B BRCA1 protein (BRCA1) mRNA, partial cds.
AF045581 - Homo sapiens BRCA1 associated protein 1 (BAP1) mRNA, complete cds.
MF590173 - Homo sapiens isolate D-patient-1 BRCA1 mRNA, partial cds.
MF590174 - Homo sapiens isolate D-patient-2 BRCA1 mRNA, partial cds.
MF590175 - Homo sapiens isolate D-patient-3 BRCA1 mRNA, partial cds.
MF590176 - Homo sapiens isolate D-patient-4 BRCA1 mRNA, partial cds.
MF590177 - Homo sapiens isolate D-patient-5 BRCA1 mRNA, partial cds.
MF590178 - Homo sapiens isolate D-patient-6 BRCA1 mRNA, partial cds.
MF590179 - Homo sapiens isolate D-patient-7 BRCA1 mRNA, partial cds.
MF590180 - Homo sapiens isolate D-patient-8 BRCA1 mRNA, partial cds.
MF590181 - Homo sapiens isolate D-patient-9 BRCA1 mRNA, partial cds.
MF590182 - Homo sapiens isolate D-patient-10 BRCA1 mRNA, partial cds.
AF005068 - Homo sapiens breast and ovarian cancer susceptibility protein splice variant (BRCA1) mRNA, complete cds.
AF274503 - Homo sapiens breast and ovarian cancer susceptibility (BRCA1) pseudogene, partial mRNA sequence.
AY751490 - Homo sapiens breast and ovarian cancer susceptibility protein (BRCA1) mRNA, BRCA1-2201T/2430C/2731T/3232G/3667G/4427C/4956G allele, partial cds.
AB621825 - Homo sapiens BRCA1 mRNA for breast cancer type 1 susceptibility protein, partial cds, clone: HP08575-RBd67C11.
DQ363751 - Homo sapiens breast and ovarian cancer sususceptibility protein (BRCA1) mRNA, complete cds, alternatively spliced.
JN686490 - Homo sapiens breast and ovarian cancer sususceptibility protein 1 (BRCA1) mRNA, complete cds.
KP272105 - Homo sapiens isolate TMH3501 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, partial cds.
KP272106 - Homo sapiens isolate TWH94001 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, partial cds.
MG494347 - Homo sapiens isolate TWH-1562-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494348 - Homo sapiens isolate TWH-1326-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494352 - Homo sapiens isolate HKSH-0090-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494353 - Homo sapiens isolate TWH-1519-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494354 - Homo sapiens isolate HKSH-0246-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494355 - Homo sapiens isolate HKSH-0181-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494356 - Homo sapiens isolate QMH-0112-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494357 - Homo sapiens isolate TWH-1558-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494358 - Homo sapiens isolate FP-0148-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494359 - Homo sapiens isolate FP-0163-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494360 - Homo sapiens isolate QMH-0260-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494361 - Homo sapiens isolate OV-0102-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494362 - Homo sapiens isolate TWH-1330-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494363 - Homo sapiens isolate OV-0167-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494364 - Homo sapiens isolate OV-0215-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494365 - Homo sapiens isolate HKSH-0177-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494366 - Homo sapiens isolate OV-0104-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494367 - Homo sapiens isolate FP-0157-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494368 - Homo sapiens isolate HKSH-0229-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494369 - Homo sapiens isolate TWH-0468-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494370 - Homo sapiens isolate OV-0205-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494371 - Homo sapiens isolate OV-0051-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494372 - Homo sapiens isolate TWH-1552-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494373 - Homo sapiens isolate HKSH-0186-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MG494374 - Homo sapiens isolate TWH-1304-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
U14680 - Homo sapiens breast and ovarian cancer susceptibility (BRCA1) mRNA, complete cds.
U68041 - Human breast and ovarian cancer susceptibility protein (BRCA1) mRNA, partial cds.
Y08864 - H.sapiens mRNA for breast and ovarian cancer susceptibility protein (BRCA1), 3'UTR.
MK028699 - Homo sapiens isolate FP-0217-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.
MK028700 - Homo sapiens isolate TWH-1917-0-1 truncated breast and ovarian cancer susceptibility protein 1 (BRCA1) mRNA, complete cds.

GeneReviews

BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer at chr17:43044295-43125483 - (BRCA1)
BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer at chr13:32315474-32400266 - (BRCA2)