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Gencode Genes

ATF4 (ENST00000674920.3) at chr22:39520562-39522683 - <b>ATF4</b> ENST00000674920.3 Homo sapiens activating transcription factor 4 ATF4 transcript 
KLHDC2 (ENST00000298307.10) at chr14:49768153-49786385 -  ... CREB3-DNA binding Directly interacts with CREB3 but not with CREB1 <b>ATF4</b> ATF6 JUN FOS CEBPA and herpes simplex virus transactivator 
NEK6 (ENST00000320246.10) at chr9:124257949-124353307 -  ... at metaphase-anaphase transition robust mitotic spindle formation and cytokinesis Phosphorylates <b>ATF4</b> CIR1 PTN RAD26L RBBP6 RPS7 RPS6KB1 TRIP4 STAT3 and 
TXLNG (ENST00000380122.10) at chrX:16786466-16844519 -  ... Dec 2009 May be involved in intracellular vesicle traffic Inhibits <b>ATF4-mediated</b> transcription possibly by dimerizing with ATF4 to form inactive 
TRIB3 (ENST00000217233.9) at chr20:380760-397559 -  ... and mask the Thr-308 phosphorylation site in AKT1 Binds to <b>ATF4</b> and inhibits its transcriptional activation activity Interacts with the 
HAUS7 (ENST00000370211.10) at chrX:153447668-153470576 -  ... this interaction is required for spindle assembly Binds UCHL5 Q96AQ3 <b>ATF4</b> NbExp 2 IntAct EBI-395719 EBI-740263 Cytoplasm cytoskeleton centrosome Cytoplasm 
CHAC1 (ENST00000617768.5) at chr15:40953471-40956512 -  ... protein response pathway by mediating the pro-apoptotic effects of the <b>ATF4-ATF3-DDIT3</b> CHOP cascade Interacts with NOTCH1 via extracellular region By 
CUL1 (ENST00000325222.9) at chr7:148698903-148801110 -  ... of phosphorylated NFKBIA SCF BTRC directs ubiquitination of NFKBIB NFKBIE <b>ATF4</b> SMAD3 SMAD4 CDC25A FBXO5 and probably NFKB2 SCF SKP2 
CEP290 (ENST00000552810.6) at chr12:88049016-88142088 -  ... ciliogenesis and may regulate ciliary membrane composition By similarity Activates <b>ATF4-mediated</b> transcription Required for the correct localization of ciliary and 
SATB2 (ENST00000417098.6) at chr2:199269505-199457939 -  ... transcriptional network regulating skeletal development and osteoblast differentiation Interacts with <b>ATF4</b> and RUNX2 resulting in enhanced DNA binding and transactivation 
FOXO1 (ENST00000379561.6) at chr13:40555667-40666641 -  ... of the skeleton in regulating glucose metabolism Acts syngernistically with <b>ATF4</b> to suppress osteocalcin BGLAP activity increasing glucose levels and 
DISC1 (ENST00000439617.8) at chr1:231626790-232041272 -  ... with GSK3B By similarity Interacts with tubulin alpha ACTN2 ANKHD1 <b>ATF4</b> ATF5 CEP63 EIF3S3 MAP1A NDEL1 PAFAH1B1 RANBP9 SPTBN4 SYNE1 
DAPK2 (ENST00000457488.6) at chr15:63907036-64046485 -  ... similarity Isoform 2 but not isoform 1 can interact with <b>ATF4</b> Self NbExp 4 IntAct EBI-77154 EBI-77154 Cytoplasm Cytoplasmic vesicle 
BTRC (ENST00000370187.8) at chr10:101354165-101557313 -  ... the ubiquitination of phosphorylated NFKB1 nuclear factor NF-kappa-B p105 subunit <b>ATF4</b> SMAD3 SMAD4 CDC25A DLG1 FBXO5 and probably NFKB2 SCF 
GABBR2 (ENST00000259455.4) at chr9:98288109-98708935 -  ... and homodimeric assembly does not seem to happen Interacts with <b>ATF4</b> via its C-terminal region Cell membrane Multi-pass membrane protein 
GABBR1 (ENST00000377034.9) at chr6:29602238-29633183 -  ... with the leucine zipper of the C-terminal bZIP domain of <b>ATF4</b> via its C-terminal region Interacts with JAKMIP1 P61244 MAX 
GABBR1 (ENST00000449163.5) at chr6_GL000250v2_alt:821307-893756 -  ... with the leucine zipper of the C-terminal bZIP domain of <b>ATF4</b> via its C-terminal region Interacts with JAKMIP1 P61244 MAX 
GABBR1 (ENST00000438094.5) at chr6_GL000251v2_alt:1042093-1114519 -  ... with the leucine zipper of the C-terminal bZIP domain of <b>ATF4</b> via its C-terminal region Interacts with JAKMIP1 P61244 MAX 
GABBR1 (ENST00000417759.5) at chr6_GL000252v2_alt:821155-893588 -  ... with the leucine zipper of the C-terminal bZIP domain of <b>ATF4</b> via its C-terminal region Interacts with JAKMIP1 P61244 MAX 
GABBR1 (ENST00000448754.5) at chr6_GL000253v2_alt:820771-893182 -  ... with the leucine zipper of the C-terminal bZIP domain of <b>ATF4</b> via its C-terminal region Interacts with JAKMIP1 P61244 MAX 
GABBR1 (ENST00000383639.6) at chr6_GL000255v2_alt:821111-893551 -  ... with the leucine zipper of the C-terminal bZIP domain of <b>ATF4</b> via its C-terminal region Interacts with JAKMIP1 P61244 MAX 
GABBR1 (ENST00000383543.7) at chr6_GL000254v2_alt:821016-893432 -  ... with the leucine zipper of the C-terminal bZIP domain of <b>ATF4</b> via its C-terminal region Interacts with JAKMIP1 P61244 MAX 
DAPK3 (ENST00000545797.7) at chr19:3958453-3971099 -  ... homotrimer Can also exist as homodimer or form heterodimers with <b>ATF4</b> Homodimerization is required for activation segment autophosphorylation Both interactions 
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