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Gencode Genes

ALPL (ENST00000374840.8) at chr1:21509423-21578410 - Homo sapiens alkaline phosphatase, biomineralization associated (ALPL), transcript variant 6, mRNA. (from RefSeq NM_001369805)
ALPL (ENST00000540617.5) at chr1:21509428-21578175 - Homo sapiens alkaline phosphatase, biomineralization associated (ALPL), transcript variant 2, mRNA. (from RefSeq NM_001127501)
ALPL (ENST00000539907.5) at chr1:21509426-21578399 - Homo sapiens alkaline phosphatase, biomineralization associated (ALPL), transcript variant 3, mRNA. (from RefSeq NM_001177520)
ALPL (ENST00000468526.1) at chr1:21509397-21564211 - alkaline phosphatase, liver/bone/kidney (from HGNC ALPL)
ALPL (ENST00000374832.5) at chr1:21551279-21578012 - Homo sapiens alkaline phosphatase, biomineralization associated (ALPL), transcript variant 4, mRNA. (from RefSeq NM_001369803)
ALPL (ENST00000374830.2) at chr1:21570303-21577731 - alkaline phosphatase, liver/bone/kidney (from HGNC ALPL)
ALPL (ENST00000374829.2) at chr1:21574478-21578399 - alkaline phosphatase, liver/bone/kidney (from HGNC ALPL)
DLX5 (ENST00000486603.2) at chr7:97021978-97024950 - Transcriptional factor involved in bone development.  Acts as an immediate early BMP-responsive transcriptional  activator essential for osteoblast differentiation. Stimulates  ALPL promoter activity in a RUNX2-independent manner during  osteoblast differentiation. Stimulates SP7 promoter activity  during osteoblast differentiation. Promotes cell proliferation by  up-regulating MYC promoter activity. Involved as a positive  regulator of both chondrogenesis and chondrocyte hypertrophy in  the endochondral skeleton. Binds to the homeodomain-response  element of the ALPL and SP7 promoter. Binds to the MYC promoter.  Requires the 5'-TAATTA-3' consensus sequence for DNA-binding. (from UniProt P56178)
MSX2 (ENST00000239243.7) at chr5:174724582-174730896 - Homo sapiens msh homeobox 2 (MSX2), transcript variant 1, mRNA. (from RefSeq NM_002449)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_001177520.2 at chr1:21509358-21578412
NM_001127501.3 at chr1:21509358-21578412
NM_000478.5 at chr1:21509358-21578412

NCBI RefSeq genes, predicted subset (XM_* or XR_*)

XM_005245818.1 at chr1:21508982-21578412
XM_006710546.3 at chr1:21551320-21578412
XM_017000903.1 at chr1:21560680-21578412

NCBI RefSeq and Ensembl transcripts from the MANE Project (v0.6)

ALPL at chr1:21509423-21578410

RefSeq Genes

ALPL at chr1:21509423-21578410 - (NM_001127501) alkaline phosphatase, tissue-nonspecific isozyme isoform 2
ALPL at chr1:21509423-21578410 - (NM_000478) alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein
ALPL at chr1:21509423-21578410 - (NM_001177520) alkaline phosphatase, tissue-nonspecific isozyme isoform 3
ALPL at chr1:21551270-21578410 - (NM_001369803) alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein
ALPL at chr1:21508984-21578410 - (NM_001369804) alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein
ALPL at chr1:21508984-21578410 - (NM_001369805) alkaline phosphatase, tissue-nonspecific isozyme isoform 1 precursor preproprotein

Non-Human RefSeq Genes

ALPL at chr1:21561080-21577564 - (NM_205360) alkaline phosphatase, tissue-nonspecific isozyme precursor
ALPL at chr1:21553976-21577683 - (NM_001266869) alkaline phosphatase, tissue-nonspecific isozyme precursor
ALPL at chr1:21509474-21578397 - (NM_001185034) alkaline phosphatase, tissue-nonspecific isozyme precursor
Alpl at chr1:21554082-21577656 - (NM_001290262) alkaline phosphatase, tissue-nonspecific isozyme precursor
alpl at chr1:21560624-21577567 - (NM_001032651) alkaline phosphatase, tissue-nonspecific isozyme precursor
Alpl at chr1:21553976-21578399 - (NM_013059) alkaline phosphatase, tissue-nonspecific isozyme precursor
ALPL at chr1:21560587-21578500 - (NM_001197137) alkaline phosphatase, tissue-nonspecific isozyme
ALPL at chr1:21553976-21578400 - (NM_176858) alkaline phosphatase, tissue-nonspecific isozyme precursor
alpl at chr1:21561096-21577564 - (NM_201007) alkaline phosphatase, tissue-nonspecific isozyme
ALPL at chr1:21553976-21577986 - (NM_001042563) alkaline phosphatase, tissue-nonspecific isozyme precursor
alpl at chr1:21560625-21577564 - (NM_001303340) alkaline phosphatase, tissue-nonspecific isozyme
Alpl at chr1:21547386-21578408 - (NM_001287172) alkaline phosphatase, tissue-nonspecific isozyme preproprotein
Alpl at chr1:21553976-21578408 - (NM_007431) alkaline phosphatase, tissue-nonspecific isozyme preproprotein
alpl.L at chr1:21560625-21577564 - (NM_001087426) tissue-nonspecific alkaline phosphatase precursor

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

ALPL at chr1:21509423-21578410
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

ALPL at chr1:21509397-21564211
ALPL at chr1:21509423-21578410
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

ALPL at chr1:21509372-21578412
ALPL at chr1:21509397-21564211
ALPL at chr1:21509426-21578399
ALPL at chr1:21509428-21578175
ALPL at chr1:21551279-21578012
ALPL at chr1:21570303-21577731
ALPL at chr1:21574478-21578399

International Knockout Mouse Consortium Genes Mapped to Human Genome

Alpl_33808 at chr1:21509365-21578412
Alpl_33809 at chr1:21509365-21578412
Alpl_33810 at chr1:21509365-21578412
Alpl_33811 at chr1:21509365-21578412
Alpl_75483 at chr1:21509365-21578412
Alpl_76494 at chr1:21509365-21578412
Alpl_VG17306 at chr1:21509365-21578412

Human Aligned mRNA Search Results

AB209814 - Homo sapiens mRNA for ALPL protein variant protein.
BC021289 - Homo sapiens alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:29601 IMAGE:5087597), complete cds.
BC066116 - Homo sapiens alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:60186 IMAGE:5754297), complete cds.
BC090861 - Homo sapiens alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:102779 IMAGE:6181160), complete cds.
BC110909 - Homo sapiens alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:131983 IMAGE:5752191), complete cds.
BC126165 - Homo sapiens alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:161443 IMAGE:8991881), complete cds.
BC136325 - Homo sapiens alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:167935 IMAGE:9020312), complete cds.
AK312667 - Homo sapiens cDNA, FLJ93059, highly similar to Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), mRNA.

Non-Human Aligned mRNA Search Results

BC108491 - Xenopus laevis alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:130818 IMAGE:7977142), complete cds.
BC043760 - Xenopus laevis alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:52917 IMAGE:4889595), complete cds.
AB473959 - Mus musculus Alpl mRNA for alkaline phosphatase, complete cds.
BC065175 - Mus musculus alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:90091 IMAGE:6807509), complete cds.
BC088399 - Rattus norvegicus alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:93545 IMAGE:7128677), complete cds.
JQ928734 - Mesocricetus auratus alkaline phosphatase (Alpl) mRNA, partial cds.
U31569 - Felis catus alkaline phosphatase (alpl) mRNA, complete cds.
JX847415 - Danio rerio strain AB/Tuebingen tissue-nonspecific alkaline phosphatase (alpl) mRNA, complete cds.
KX218235 - Eptesicus fuscus alkaline phosphatase (ALPL) mRNA, partial cds.
KX218236 - Carollia perspicillata alkaline phosphatase (ALPL) mRNA, partial cds.
BC118208 - Bos taurus alkaline phosphatase, liver/bone/kidney, mRNA (cDNA clone MGC:139479 IMAGE:8215256), complete cds.
GQ465850 - Callithrix jacchus brain tissue nonspecific alkaline phosphatase (ALPL) mRNA, complete cds.
JU324639 - TSA: Macaca mulatta Mamu_527497 mRNA sequence.
JU329142 - TSA: Macaca mulatta Mamu_518543 mRNA sequence.
JU330780 - TSA: Macaca mulatta Mamu_529480 mRNA sequence.
JV045034 - TSA: Macaca mulatta Mamu_423618 mRNA sequence.
JV635823 - TSA: Macaca mulatta Mamu_480695 mRNA sequence.
MK310189 - Bos taurus alkaline phosphatase (ALPL) mRNA, partial cds.
AB171589 - Macaca fascicularis brain cDNA clone: QflA-15503, similar to human alkaline phosphatase, liver/bone/kidney (ALPL), mRNA, RefSeq: NM_000478.2.

GeneReviews

ALPL at chr1:21509423-21578410