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Gencode Genes

ADRB2 (ENST00000305988.5) at chr5:148825245-148828687 - Homo sapiens adrenoceptor beta 2 (ADRB2), mRNA. (from RefSeq NM_000024)
USP33 (ENST00000357428.5) at chr1:77695991-77745462 - Deubiquitinating enzyme involved in various processes  such as cellular migration and beta-2 adrenergic receptor/ADRB2  recycling. Involved in cell migration via its interaction with  intracellular domain of ROBO1, leading to regulate the Slit  signaling. Plays a role in commissural axon guidance cross the  ventral midline of the neural tube in a Slit-dependent manner,  possibly by mediating the deubiquitination of ROBO1. Acts as a  regulator of G-protein coupled receptor (GPCR) signaling by  mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2)  and beta-2 adrenergic receptor (ADRB2). Plays a central role in  ADRB2 recycling and resensitization after prolonged agonist  stimulation by constitutively binding ADRB2, mediating  deubiquitination of ADRB2 and inhibiting lysosomal trafficking of  ADRB2. Upon dissociation, it is probably transferred to the  translocated beta-arrestins, leading to beta-arrestins  deubiquitination and disengagement from ADRB2. This suggests the  existence of a dynamic exchange between the ADRB2 and beta-  arrestins. Deubiquitinates DIO2, thereby regulating thyroid  hormone regulation. Mediates deubiquitination of both 'Lys-48'-  and 'Lys-63'-linked polyubiquitin chains. (from UniProt Q8TEY7)
SLC9A3R1 (ENST00000413388.2) at chr17:74762003-74769296 - Scaffold protein that connects plasma membrane proteins  with members of the ezrin/moesin/radixin family and thereby helps  to link them to the actin cytoskeleton and to regulate their  surface expression. Necessary for recycling of internalized ADRB2.  Was first known to play a role in the regulation of the activity  and subcellular location of SLC9A3. Necessary for cAMP-mediated  phosphorylation and inhibition of SLC9A3. May enhance Wnt  signaling. May participate in HTR4 targeting to microvilli (By  similarity). Involved in the regulation of phosphate reabsorption  in the renal proximal tubules. (from UniProt O14745)
MGRN1 (ENST00000586183.5) at chr16:4624961-4689039 - E3 ubiquitin-protein ligase. Mediates monoubiquitination  at multiple sites of TSG101 in the presence of UBE2D1, but not of  UBE2G1, nor UBE2H. Plays a role in the regulation of endosome-to-  lysosome trafficking. Impairs MC1R- and MC4R-signaling by  competing with GNAS-binding to MCRs and inhibiting agonist-induced  cAMP production. Does not inhibit ADRB2-signaling. Does not  promote MC1R ubiquitination. (from UniProt O60291)
GPRASP1 (ENST00000652542.1) at chrX:102651092-102659074 - May modulate lysosomal sorting and functional down-  regulation of a variety of G-protein coupled receptors. Targets  receptors for degradation in lysosomes. (from UniProt Q5JY77)
GPRASP1 (ENST00000537097.2) at chrX:102651483-102659083 - Homo sapiens G protein-coupled receptor associated sorting protein 1 (GPRASP1), transcript variant 4, mRNA. (from RefSeq NM_001184727)
GPRASP1 (ENST00000444152.5) at chrX:102651366-102659080 - Homo sapiens G protein-coupled receptor associated sorting protein 1 (GPRASP1), transcript variant 3, mRNA. (from RefSeq NM_001099411)
GPRASP1 (ENST00000415986.5) at chrX:102651366-102659080 - Homo sapiens G protein-coupled receptor associated sorting protein 1 (GPRASP1), transcript variant 2, mRNA. (from RefSeq NM_001099410)
GPRASP1 (ENST00000361600.9) at chrX:102651366-102659083 - Homo sapiens G protein-coupled receptor associated sorting protein 1 (GPRASP1), transcript variant 1, mRNA. (from RefSeq NM_014710)
USP33 (ENST00000370794.7) at chr1:77695987-77759852 - Homo sapiens ubiquitin specific peptidase 33 (USP33), transcript variant 2, mRNA. (from RefSeq NM_201624)
USP33 (ENST00000370793.5) at chr1:77695991-77759852 - Homo sapiens ubiquitin specific peptidase 33 (USP33), transcript variant 1, mRNA. (from RefSeq NM_015017)
USP33 (ENST00000370792.7) at chr1:77711652-77759852 - Homo sapiens ubiquitin specific peptidase 33 (USP33), transcript variant 3, mRNA. (from RefSeq NM_201626)
MGRN1 (ENST00000415496.5) at chr16:4624824-4690974 - Homo sapiens mahogunin ring finger 1 (MGRN1), transcript variant 4, mRNA. (from RefSeq NM_001142291)
MGRN1 (ENST00000588994.5) at chr16:4624961-4688908 - Homo sapiens mahogunin ring finger 1 (MGRN1), transcript variant 2, mRNA. (from RefSeq NM_001142289)
MGRN1 (ENST00000399577.9) at chr16:4624868-4690972 - Homo sapiens mahogunin ring finger 1 (MGRN1), transcript variant 3, mRNA. (from RefSeq NM_001142290)
MGRN1 (ENST00000262370.12) at chr16:4624826-4690972 - Homo sapiens mahogunin ring finger 1 (MGRN1), transcript variant 1, mRNA. (from RefSeq NM_015246)
USP20 (ENST00000358355.5) at chr9:129835478-129881828 - Homo sapiens ubiquitin specific peptidase 20 (USP20), transcript variant 2, mRNA. (from RefSeq NM_001008563)
USP20 (ENST00000372429.7) at chr9:129835446-129881838 - Homo sapiens ubiquitin specific peptidase 20 (USP20), transcript variant 1, mRNA. (from RefSeq NM_006676)
USP20 (ENST00000315480.9) at chr9:129835458-129881828 - Homo sapiens ubiquitin specific peptidase 20 (USP20), transcript variant 3, mRNA. (from RefSeq NM_001110303)
GRK4 (ENST00000504933.1) at chr4:2963821-3040747 - Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant 3, mRNA. (from RefSeq NM_001004057)
GRK4 (ENST00000398051.8) at chr4:2963608-3040727 - Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant 4, mRNA. (from RefSeq NM_005307)
GRK4 (ENST00000345167.10) at chr4:2963821-3040747 - Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant 5, mRNA. (from RefSeq NM_001350173)
GRK4 (ENST00000398052.9) at chr4:2963571-3040760 - Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant 1, mRNA. (from RefSeq NM_182982)
EGLN3 (ENST00000250457.8) at chr14:33924227-33951074 - Homo sapiens egl-9 family hypoxia inducible factor 3 (EGLN3), transcript variant 1, mRNA. (from RefSeq NM_022073)
SLC9A3R2 (ENST00000424542.7) at chr16:2026902-2039026 - Homo sapiens SLC9A3 regulator 2 (SLC9A3R2), transcript variant 1, mRNA. (from RefSeq NM_001130012)
SLC9A3R2 (ENST00000566198.1) at chr16:2033271-2038421 - Homo sapiens SLC9A3 regulator 2 (SLC9A3R2), transcript variant 5, mRNA. (from RefSeq NM_001252076)
SLC9A3R2 (ENST00000432365.6) at chr16:2026928-2038489 - Homo sapiens SLC9A3 regulator 2 (SLC9A3R2), transcript variant 2, mRNA. (from RefSeq NM_004785)
VHL (ENST00000256474.2) at chr3:10141008-10152220 - Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA. (from RefSeq NM_000551)
VHL (ENST00000345392.2) at chr3:10141788-10152082 - Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 2, mRNA. (from RefSeq NM_198156)
PLCE1 (ENST00000371375.1) at chr10:94089095-94325609 - The production of the second messenger molecules  diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is  mediated by activated phosphatidylinositol-specific phospholipase  C enzymes. PLCE1 is a bifunctional enzyme which also regulates  small GTPases of the Ras superfamily through its Ras guanine-  exchange factor (RasGEF) activity. As an effector of  heterotrimeric and small G-protein, it may play a role in cell  survival, cell growth, actin organization and T-cell activation. (from UniProt Q9P212)
SLC9A3R1 (ENST00000262613.10) at chr17:74748628-74769353 - Homo sapiens SLC9A3 regulator 1 (SLC9A3R1), mRNA. (from RefSeq NM_004252)
TPM2 (ENST00000645482.2) at chr9:35682926-35690056 - Homo sapiens tropomyosin 2 (TPM2), transcript variant Tpm2.2, mRNA. (from RefSeq NM_003289)
PLCE1 (ENST00000371380.7) at chr10:94030812-94332823 - Homo sapiens phospholipase C epsilon 1 (PLCE1), transcript variant 1, mRNA. (from RefSeq NM_016341)
ARRB1 (ENST00000360025.7) at chr11:75265599-75351705 - Homo sapiens arrestin beta 1 (ARRB1), transcript variant 2, mRNA. (from RefSeq NM_020251)
ARRB1 (ENST00000420843.7) at chr11:75260122-75351661 - Homo sapiens arrestin beta 1 (ARRB1), transcript variant 1, mRNA. (from RefSeq NM_004041)
PLCE1 (ENST00000371385.7) at chr10:94089026-94328389 - Homo sapiens phospholipase C epsilon 1 (PLCE1), transcript variant 2, mRNA. (from RefSeq NM_001165979)
ARRB2 (ENST00000412477.7) at chr17:4710693-4721496 - Homo sapiens arrestin beta 2 (ARRB2), transcript variant 3, mRNA. (from RefSeq NM_001257328)
ARRB2 (ENST00000381488.10) at chr17:4710693-4721061 - Homo sapiens arrestin beta 2 (ARRB2), transcript variant 2, mRNA. (from RefSeq NM_199004)
ARRB2 (ENST00000346341.6) at chr17:4710634-4721499 - Homo sapiens arrestin beta 2 (ARRB2), transcript variant 6, mRNA. (from RefSeq NM_001257331)
ARRB2 (ENST00000269260.7) at chr17:4710632-4721497 - Homo sapiens arrestin beta 2 (ARRB2), transcript variant 1, mRNA. (from RefSeq NM_004313)

NCBI RefSeq genes, curated subset (NM_*, NR_*, NP_* or YP_*)

NM_000024.5 at chr5:148826593-148828634

RefSeq Genes

ADRB2 at chr5:148826593-148828634 - (NM_000024) beta-2 adrenergic receptor

Non-Human RefSeq Genes

ADRB2 at chr5:148826832-148828073 - (NM_001130154) beta-2 adrenergic receptor
ADRB2 at chr5:148826832-148828073 - (NM_001287285) beta-2 adrenergic receptor
adrb2 at chr5:148826924-148827893 - (NM_001123425) beta-2 adrenergic receptor
ADRB2 at chr5:148826832-148828073 - (NM_001257120) beta-2 adrenergic receptor
ADRB2 at chr5:148826593-148828634 - (NM_001195264) beta-2 adrenergic receptor
ADRB2 at chr5:148826792-148828105 - (NM_001042774) beta-2 adrenergic receptor
ADRB2 at chr5:148826691-148828623 - (NM_174231) beta-2 adrenergic receptor
ADRB2 at chr5:148826832-148828073 - (NM_001009247) beta-2 adrenergic receptor
ADRB2 at chr5:148826731-148828623 - (NM_001003234) beta-2 adrenergic receptor
ADRB2 at chr5:148826832-148828073 - (NM_001128436) beta-2 adrenergic receptor
Adrb2 at chr5:148826800-148828622 - (NM_001281948) beta-2 adrenergic receptor
Adrb2 at chr5:148826817-148828623 - (NM_012492) beta-2 adrenergic receptor
Adrb2 at chr5:148826785-148828696 - (NM_007420) beta-2 adrenergic receptor
adrb2.L at chr5:148826924-148827893 - (NM_001092322) adrenoceptor beta 2 L homeolog
adrb2.S at chr5:148826919-148827893 - (NM_001089949) uncharacterized protein LOC398915
adrb2a at chr5:148826949-148827866 - (NM_001102652) beta-2 adrenergic receptor

Basic Gene Annotation Set from GENCODE Version 33 (Ensembl 99)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 33 (Ensembl 99)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 31 (Ensembl 97)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 29 (Ensembl 94)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 28 (Ensembl 92)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 27 (Ensembl 90)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 26 (Ensembl 88)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 25 (Ensembl 85)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 24 (Ensembl 83)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 23 (Ensembl 81)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 22 (Ensembl 79)

ADRB2 at chr5:148825245-148828687

Basic Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

ADRB2 at chr5:148825245-148828687

Comprehensive Gene Annotation Set from GENCODE Version 20 (Ensembl 76)

ADRB2 at chr5:148825245-148828687

International Knockout Mouse Consortium Genes Mapped to Human Genome

Adrb2_VG12777 at chr5:148826593-148828634

Human Aligned mRNA Search Results

KJ534762 - Homo sapiens clone ADRB2_iso-A_adult-A03 adrenoceptor beta 2 surface isoform A (ADRB2) mRNA, partial cds, alternatively spliced.
AY136741 - Homo sapiens beta 2 adrenergic receptor (ADRB2) mRNA, complete cds.
BC012481 - Homo sapiens adrenergic, beta-2-, receptor, surface, mRNA (cDNA clone MGC:21367 IMAGE:4538187), complete cds.
BC063486 - Homo sapiens adrenergic, beta-2-, receptor, surface, mRNA (cDNA clone MGC:74793 IMAGE:5241774), complete cds.
BC073856 - Homo sapiens adrenergic, beta-2-, receptor, surface, mRNA (cDNA clone MGC:90247 IMAGE:5217922), complete cds.
M15169 - Human beta-2-adrenergic receptor mRNA, complete cds.
AK313151 - Homo sapiens cDNA, FLJ93644, highly similar to Homo sapiens adrenergic, beta-2-, receptor, surface (ADRB2), mRNA.

Non-Human Aligned mRNA Search Results

BC160515 - Xenopus tropicalis adrenergic, beta-2-, receptor, surface, mRNA (cDNA clone MGC:135860 IMAGE:7712531), complete cds.
BC030346 - Mus musculus adrenergic receptor, beta 2, mRNA (cDNA clone IMAGE:4987488), partial cds.
AB469813 - Danio rerio adrb2b mRNA for beta-2b-adrenergic receptor, complete cds.
AB294718 - Danio rerio adrb2a mRNA for beta-2-adrenergic receptor a, complete cds.
FR823440 - Cyprinus carpio mRNA for beta 2a adrenergic receptor (adrb2a gene), strain R3xR8.
BC032883 - Mus musculus adrenergic receptor, beta 2, mRNA (cDNA clone MGC:41462 IMAGE:1349283), complete cds.
BC086538 - Rattus norvegicus adrenergic, beta-2-, receptor, surface, mRNA (cDNA clone MGC:105506 IMAGE:7114502), complete cds.
MK209639 - Oryctolagus cuniculus breed New Zealand White beta-2 adrenergic receptor (Adrb2) mRNA, partial cds.
EU723260 - Ovis aries adrenergic receptor beta-2 (ADRB2) mRNA, partial cds.
BC114132 - Bos taurus adrenergic, beta-2-, receptor, surface, mRNA (cDNA clone MGC:137344 IMAGE:8169617), complete cds.
KC503765 - Anguilla anguilla beta 2 adrenergic receptor (ADRB2) mRNA, partial cds.
MK139003 - Gallus gallus adrenoceptor beta 2 (ADRB2) mRNA, complete cds.