miRNA Tissue Atlas Track Settings
 
Tissue-Specific microRNA Expression from Two Individuals   (All Expression tracks)

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 Sample 1  miRNA Tissue Atlas microRna Expression   Schema 
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 Sample 2  miRNA Tissue Atlas microRna Expression   Schema 

Description

The Human miRNA Tissue Atlas is a catalog of tissue-specific microRNA (miRNA) expression across 62 tissues. This track contains quantile normalized miRNA expression data sampled from two individuals and mapped to miRBase v21 coordinates. The track contains two subtracks, one for each individual sampled.

The Tissue Specificity Index (TSI) is analogous to the "tau" value for mRNA expression, and is calculated as described in the associated publication. Values closer to 0 indicate miRNAs expressed in many or all tissues, while values closer to 1 indicate miRNAs expressed only in a specific tissue or tissues. To browse miRNAs by TSI value, please see the miRNA Tissue Atlas.

Display Conventions and Configuration

This track is formatted as a barChart track, similar to the GTEx or the TCGA Cancer Expression tracks, where the heights of each bar indicate the expression value for the miRNA in a specific tissue. The tissues sampled are described in the table below:

Bar ColorSample 1Sample 2
AdipocyteAdipocyte
ArteryArtery
ColonColon
Dura materDura mater
KidneyKidney
LiverLiver
LungLung
MuscleMuscle
MyocardiumMyocardium
SkinSkin
SpleenSpleen
StomachStomach
TestisTestis
ThyroidThyroid
Small intestine
Bone
Gallbladder
Fascia
Bladder
Epididymis
Tunica albuginea
Nervus intercostalis
Arachnoid mater
Brain
Small intestine duodenum
Small intestine jejunum
Pancreas
Kidney glandula suprarenalis
Kidney cortex renalis
Esophagus
Prostate
Bone marrow
Vein
Lymph node
Nerve not specified
Pleura
Pituitary gland
Spinal cord
Thalamus
Brain white matter
Nucleus caudatus
Kidney medulla renalis
Brain gray_matter
Cerebral cortex temporal
Cerebral cortex frontal
Cerebral cortex occipital
Cerebellum

The 14 shared tissues sampled across both individuals are presented in the same order for easier comparison.

Data Access

The underlying expression matrix and TSI values can be obtained from the miRNA tissue atlas website, in the data_matrix_quantile.txt and tsi_quantile.csv files.

References

Ludwig N, Leidinger P, Becker K, Backes C, Fehlmann T, Pallasch C, Rheinheimer S, Meder B, Stähler C, Meese E et al. Distribution of miRNA expression across human tissues. Nucleic Acids Res. 2016 May 5;44(8):3865-77. PMID: 26921406; PMC: PMC4856985