Gene interactions and pathways from curated databases and text-mining

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CASP3 — IL7

Text-mined interactions from Literome

Guo et al., Blood 2003 : In the present study we confirm that Fas signaling induces both phenotypic and functional maturation of murine DCs, and we demonstrate that phenotypic maturation is associated with phosphorylation of extracellular signal regulated kinase ( ERK ) 1/2, activation of caspase-1 , and secretion of interleukin-beta ( IL-1beta )
Wang et al., Ann Thorac Surg 2005 (Reperfusion Injury) : Myocardial tissue was then assessed for products of p38 MAPK activation, expression of tumor necrosis factor, interleukin-1beta and interleukin-6, and activation of caspase-1, caspase-3 and caspase-11
Harman et al., J Immunol 2008 : Furthermore, unlike common lymphoid progenitors that readily generate B cells upon stimulation with IL-7, c-Kit ( - ) Sca-1 ( high ) Flt3 ( + ) precursors do not express abundant levels of the IL-7R , and require costimulation with Flt3 ligand and IL-7 to generate B cells in vitro
Shushanov et al., Bull Exp Biol Med 2010 : Insulin-like growth factor-1 and insulin inhibit caspase-3/7 activation initiated by interleukin-1ß in the rat eye retinal neurons
Liao et al., Inflamm Res 2013 : Lipopolysaccharide/adenosine triphosphate mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1 mediated interleukin-1ß secretion
Lee et al., Oncogene 1996 (Lymphoma, T-Cell) : Interleukin-7 inhibits apoptosis of mouse malignant T-lymphoma cells by both suppressing the CPP32-like protease activation and inducing the Bcl-2 expression