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IL11 — IL22
Text-mined interactions from Literome
Andoh et al., Gastroenterology 2005
(Inflammatory Bowel Diseases) :
cDNA microarray analyses demonstrated that, in colonic SEMFs,
IL-22 increased the messenger RNA ( mRNA ) expression of inflammatory cytokines ( IL-6, IL-8,
IL-11 , and leukemia inhibitory factor [LIF ] ), chemokines, and matrix metalloproteinases ...
IL-22 induced an activation of nuclear factor (NF)-kappaB and activating protein (AP)-1 within 1 hour, and a blockade of NF-kappaB and AP-1 activation markedly
reduced IL-22 induction of IL-6, IL-8,
IL-11 , and LIF mRNA
Marijnissen et al., Arthritis Rheum 2011
(Arthritis, Experimental...) :
Increased expression of
interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is
controlled by
interleukin-1 and enhances bone degradation
Leng et al., J Immunol 1997
(Leukemia, Monocytic, Acute) :
Interleukin-11 inhibits macrophage
interleukin-12 production