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IRAK2 — TAB1

Pathways - manually collected, often from reviews:

• Reactome Reaction: IRAK2 → TAB1 (indirect_complex) Kishimoto et al., J Biol Chem 2000, Sakurai et al., FEBS Lett 2000, Takaesu et al., Mol Cell 2000, Ono et al., J Biol Chem 2001, Kanayama et al., Mol Cell 2004, Sato et al., Nat Immunol 2005, Shim et al., Genes Dev 2005, Brown et al., J Mol Biol 2005, Xia et al., Nature 2009, Kulathu et al., Nature structural & molecular biology 2009*, Shibuya et al., Science 1996
• Reactome Reaction: IRAK2 → TAB1 (reaction) Kishimoto et al., J Biol Chem 2000, Sakurai et al., FEBS Lett 2000, Takaesu et al., Mol Cell 2000, Ono et al., J Biol Chem 2001, Kanayama et al., Mol Cell 2004, Sato et al., Nat Immunol 2005, Shim et al., Genes Dev 2005, Brown et al., J Mol Biol 2005, Xia et al., Nature 2009, Kulathu et al., Nature structural & molecular biology 2009*, Shibuya et al., Science 1996

Text-mined interactions from Literome

Qian et al., J Biol Chem 2001 : Our results show that IRAK is required for the IL-1 induced phosphorylation of TAK1, TAB1 , and TAB2 ... Our results show that IRAK is required for the IL-1 induced phosphorylation of TAK1, TAB1 , and TAB2
Xiao et al., J Biol Chem 2008 : Importantly, the negative impact of Pellino 3b on IL-1 induced IRAK degradation correlated with the inhibitory effect of Pellino 3b on the IL-1 induced TAK1 dependent pathway, suggesting that a positive role of IRAK degradation in IL-1 induced TAK1 activation