Gene interactions and pathways from curated databases and text-mining

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MAP3K8 — TRAF6

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Chan et al., Biochem Biophys Res Commun 2005 : TRAF dependent association of protein kinase Tpl2/COT1 ( MAP3K8 ) with CD40
Loniewski et al., Mol Immunol 2007 : We demonstrate here that reduced level of TRAF6 ( approximately 80 % decrease ) in macrophages does not significantly affect any of the components of the TLR4 stimulated ERK pathway, including p105 phosphorylation, TPL2 degradation and ERK1/2 phosphorylation