Gene interactions and pathways from curated databases and text-mining

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MAPK4 — WNT2

Text-mined interactions from Literome

Coe et al., Br J Cancer 2006 (Carcinoma, Non-Small-Cell Lung...) : Small cell lung cancer exhibited increased expression of MRP5, activation of Wnt pathway inhibitors, and upregulation of p38 MAPK activating genes, while NSCLC showed downregulation of CDKN2A, and upregulation of MAPK9 and EGFR
Bikkavilli et al., J Cell Sci 2008 : Activation of p38 MAPK is critical for canonical Wnt-beta-catenin signaling
Jeong et al., Cell cycle (Georgetown, Tex.) 2009 : In addition, PPARdelta increased protein kinase C ( PKC ), cytosolic phospholipase A ( 2 ) ( cPLA(2) ) and p38 mitogen activated protein kinase ( p38 MAPK ) phosphorylation, and Wnt/beta-catenin activation
An et al., Bone 2010 : As a mechanism for Wnt mediated mitochondrial biogenesis, we found that Wnt increased the expression of PGC-1alpha, a critical molecules in mitochondrial biogenesis, through Erk and p38 MAPK pathway independent of beta-catenin signaling
Horst et al., Cancer Res 2012 (Cell Transformation, Neoplastic...) : Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling