Gene interactions and pathways from curated databases and text-mining

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EPHB2 — PRKCB

Text-mined interactions from Literome

Cao et al., J Biol Chem 2001 : Inhibition of anti-IgM induced translocation of protein kinase C beta I inhibits ERK2 activation and increases apoptosis
Tuttle et al., Kidney Int 2005 (Fibrosis) : PKC-beta inhibition prevented ERK 1,2 activation and fibrosis induction
Guo et al., Cancer Sci 2008 (Carcinoma, Hepatocellular...) : The phosphorylation of ERK ( 1/2 ) and p38 MAPK was regulated by upregulated protein kinase C beta (PKC beta) in HCC cells through the integrated use of PKC beta RNA interference, the PKC beta specific inhibitor enzastaurin and a PKC activator phorbol-12-myristate-13-acetate
Sauma et al., J Biol Chem 1996 (Colonic Neoplasms) : Increased expression of protein kinase C beta activates ERK3 ... Thus, while overexpression of transfected PKC beta does not lead to overexpression of ERK3 , it does lead to constitutive activation of ERK3