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NOTCH4 — SMAD5

Text-mined interactions from Literome

Quillien et al., Development 2011 : However, the activation of Notch dependent transcription does not require a canonical Smad5-DNA interaction
Grabias et al., American journal of physiology. Renal physiology 2013 (Fibrosis...) : Depletion of Notch4 in shear stimulated PTECs eventually increases the levels of active TGF-ß1 protein by approximately fivefold, recovers stable SMAD phosphorylation and ubiquitinated SMAD species, and attenuates collagen accumulation