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PTGS2 — SOAT1
Text-mined interactions from Literome
Bian et al., Proc Natl Acad Sci U S A 2005
:
We now demonstrate that ( i ) an IL-4 receptor alpha-subunit ( IL-4Ralpha )
/Stat6 dependent but T cell independent pathway is the key for the nematode induced host NOS-2 inhibition ; ( ii ) endogenous IL-4 and IL-13, the only known IL-4Ralpha ligands, are not required for activating the pathway ; and ( iii ) treatment of RAW264.7 cells with parasite cultured medium
inhibits NOS-2 expression but not
cyclooxygenase 2 expression
Orth et al., J Biol Chem 2007
:
Moreover, stimulation of Swiss 3T3 cells with PMT increased transcription of the cancer associated
STAT dependent gene
cyclooxygenase-2